目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收...目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收集肿瘤大小、病理分级、分期、肾功能水平、住院时间等数据并结合患者生存情况进行统计学分析。结果:共有39例患者进行了手术治疗,包括Boari膀胱肌瓣术16例,输尿管癌根治术23例。中位随访时间为53个月(10~84个月),18名患者死亡,其中Boari膀胱肌瓣术组死亡6例,输尿管癌根治术组死亡12例。2组的5年无膀胱癌复发存活率分别为63%和59%(P>0.05),5年肿瘤特异性生存率分别为73.8%和73.5%(P>0.05),5年生存率分别为61%和57%(P>0.05),总体存活率分别为64.8%和58.1%(P>0.05)。2组间术前肾功能无明显差异[肌酐清除率57(32~104)mL/min vs 55(30~102)mL/min,P>0.05],术后Boari膀胱肌瓣术组肾功能优于输尿管癌根治术组[肌酐清除率55(35~102)mL/min vs 43(30~89)mL/min,P<0.05]。Cox比例风险回归模型多因素分析发现肾功能水平、肿瘤大小、病理分级和病理分期是影响肿瘤患者总生存期的独立因素(P<0.05),肿瘤越大、病理分级和分期越高,患者死亡风险越大,而术后高水平的肌酐清除率可以降低疾病的死亡风险。结论:Boari膀胱肌瓣术治疗中下段输尿管癌是可行的方式。相比输尿管癌根治术,Boari膀胱肌瓣术治疗后的生存率并无明显差别,而且能保护患者肾功能。展开更多
目的探讨腹腔镜Boari膀胱壁瓣法输尿管膀胱再植术(laparoscopic ureteroneocystostomy with a Boari flap,LUBF)治疗中下段输尿管尿路上皮癌的可行性和预后。方法筛选首都医科大学附属北京朝阳医院泌尿外科2005至2016年的数据库,共19例...目的探讨腹腔镜Boari膀胱壁瓣法输尿管膀胱再植术(laparoscopic ureteroneocystostomy with a Boari flap,LUBF)治疗中下段输尿管尿路上皮癌的可行性和预后。方法筛选首都医科大学附属北京朝阳医院泌尿外科2005至2016年的数据库,共19例患者因原发性中下段输尿管尿路上皮癌接受LUBF治疗(2D腹腔镜治疗5例,3D腹腔镜治疗14例),其中,男12例,女7例,中位年龄68.0(60.0,75.0)岁,术前肾积水中度12例,重度3例,统计患者的围手术期数据、病理结果和随访结果。结果19例患者的手术均为腹腔镜下完成,未中转开放手术。手术时间180.0(145.0,210.0)min,出血量50.0(20.0,100.0)mL,住院天数14.0(12.0,18.0)d,术前和术后血清肌酐(serum creatinine,SCr)分别为(94.1±25.2)μmol/L和(88.9±32.2)μmol/L,术后1年和3年总生存率(overall survival,OS)分别为94.4%和82.6%。与2D腹腔镜手术相比,3D腹腔镜治疗的手术时间更短(P=0.033),术中出血量更少(P=0.044)。结论LUBF手术时间短、出血量少、创伤小,能帮助改善患者肾功能,是一种值得推广的手术方式;与传统2D腹腔镜技术相比,3D-LUBF具有明显的手术时间和失血量优势。展开更多
BACKGROUND Ureteroscopy is well-established as a primary treatment modality for urolithiasis.Ureteral avulsion,particularly complete or full-length avulsion with a resultant long segment of the ureter left attached to...BACKGROUND Ureteroscopy is well-established as a primary treatment modality for urolithiasis.Ureteral avulsion,particularly complete or full-length avulsion with a resultant long segment of the ureter left attached to the ureteroscope,is a rare but devastating complication of the procedure.Management of this complication is challenging.Moreover,general consensus regarding the optimal management is undetermined.We report our experience of managing a complete ureteral avulsion case via an extended Boari flap technique with long-term results.CASE SUMMARY A 41-year-old female patient subjected to complete ureteral avulsion caused by ureteroscopy was referred to our hospital.A modified,extended Boari flap technique was successfully performed to repair the full-length ureteral defect.Maximal mobilization of the bladder and affected kidney followed by psoas hitch and downward nephropexy maximized the probability of a tension-free anastomosis.Meticulous blood supply preservation to the flap also contributed to the success.During the 4-year study period,no complications except for a mild urinary frequency and a slightly lower maximum urinary flow rate were reported.The patient was satisfied with the surgical outcomes.CONCLUSION The extended Boari flap procedure is a feasible and preferred technique to manage complete ureteral avulsion,particularly in emergencies.展开更多
Introduction: Ureteral lesions, most often iatrogenic, generally follow pelvic surgery. They are serious and can be life-threatening. Uretero-vesical reimplantation using the BOARI technique, modified by KUSS, was pop...Introduction: Ureteral lesions, most often iatrogenic, generally follow pelvic surgery. They are serious and can be life-threatening. Uretero-vesical reimplantation using the BOARI technique, modified by KUSS, was popularized in humans in 1954, and appears to be the most appropriate treatment for lesions of the lower ureter with significant loss of substance. Observation: We report in this work a case of iatrogenic ligation of the pelvic ureter on a single functional kidney (of fortuitous discovery) during gynecological surgery, having led to an Alteration of the General State (important Urinoma and collapse of the renal function) and treated by the surgical technique of BOARI KUSS at the urology department of the CHU Le Luxembourg. Follow-up and postoperative follow-up were excellent. Conclusion: Surgical repair of the ureter is very often indicated in cases of stenosis or iatrogenic lesions of the ureter. The BOARI KUSS technique is a good choice in cases of significant loss of substance due to injury to the lower ureter. Gynecological surgery is the main source of these lesions, and the prognosis of the treatment depends on how early the diagnosis is made, the anatomical condition of the ureter and the expertise of the surgical team.展开更多
文摘目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收集肿瘤大小、病理分级、分期、肾功能水平、住院时间等数据并结合患者生存情况进行统计学分析。结果:共有39例患者进行了手术治疗,包括Boari膀胱肌瓣术16例,输尿管癌根治术23例。中位随访时间为53个月(10~84个月),18名患者死亡,其中Boari膀胱肌瓣术组死亡6例,输尿管癌根治术组死亡12例。2组的5年无膀胱癌复发存活率分别为63%和59%(P>0.05),5年肿瘤特异性生存率分别为73.8%和73.5%(P>0.05),5年生存率分别为61%和57%(P>0.05),总体存活率分别为64.8%和58.1%(P>0.05)。2组间术前肾功能无明显差异[肌酐清除率57(32~104)mL/min vs 55(30~102)mL/min,P>0.05],术后Boari膀胱肌瓣术组肾功能优于输尿管癌根治术组[肌酐清除率55(35~102)mL/min vs 43(30~89)mL/min,P<0.05]。Cox比例风险回归模型多因素分析发现肾功能水平、肿瘤大小、病理分级和病理分期是影响肿瘤患者总生存期的独立因素(P<0.05),肿瘤越大、病理分级和分期越高,患者死亡风险越大,而术后高水平的肌酐清除率可以降低疾病的死亡风险。结论:Boari膀胱肌瓣术治疗中下段输尿管癌是可行的方式。相比输尿管癌根治术,Boari膀胱肌瓣术治疗后的生存率并无明显差别,而且能保护患者肾功能。
文摘目的探讨腹腔镜Boari膀胱壁瓣法输尿管膀胱再植术(laparoscopic ureteroneocystostomy with a Boari flap,LUBF)治疗中下段输尿管尿路上皮癌的可行性和预后。方法筛选首都医科大学附属北京朝阳医院泌尿外科2005至2016年的数据库,共19例患者因原发性中下段输尿管尿路上皮癌接受LUBF治疗(2D腹腔镜治疗5例,3D腹腔镜治疗14例),其中,男12例,女7例,中位年龄68.0(60.0,75.0)岁,术前肾积水中度12例,重度3例,统计患者的围手术期数据、病理结果和随访结果。结果19例患者的手术均为腹腔镜下完成,未中转开放手术。手术时间180.0(145.0,210.0)min,出血量50.0(20.0,100.0)mL,住院天数14.0(12.0,18.0)d,术前和术后血清肌酐(serum creatinine,SCr)分别为(94.1±25.2)μmol/L和(88.9±32.2)μmol/L,术后1年和3年总生存率(overall survival,OS)分别为94.4%和82.6%。与2D腹腔镜手术相比,3D腹腔镜治疗的手术时间更短(P=0.033),术中出血量更少(P=0.044)。结论LUBF手术时间短、出血量少、创伤小,能帮助改善患者肾功能,是一种值得推广的手术方式;与传统2D腹腔镜技术相比,3D-LUBF具有明显的手术时间和失血量优势。
文摘BACKGROUND Ureteroscopy is well-established as a primary treatment modality for urolithiasis.Ureteral avulsion,particularly complete or full-length avulsion with a resultant long segment of the ureter left attached to the ureteroscope,is a rare but devastating complication of the procedure.Management of this complication is challenging.Moreover,general consensus regarding the optimal management is undetermined.We report our experience of managing a complete ureteral avulsion case via an extended Boari flap technique with long-term results.CASE SUMMARY A 41-year-old female patient subjected to complete ureteral avulsion caused by ureteroscopy was referred to our hospital.A modified,extended Boari flap technique was successfully performed to repair the full-length ureteral defect.Maximal mobilization of the bladder and affected kidney followed by psoas hitch and downward nephropexy maximized the probability of a tension-free anastomosis.Meticulous blood supply preservation to the flap also contributed to the success.During the 4-year study period,no complications except for a mild urinary frequency and a slightly lower maximum urinary flow rate were reported.The patient was satisfied with the surgical outcomes.CONCLUSION The extended Boari flap procedure is a feasible and preferred technique to manage complete ureteral avulsion,particularly in emergencies.
文摘Introduction: Ureteral lesions, most often iatrogenic, generally follow pelvic surgery. They are serious and can be life-threatening. Uretero-vesical reimplantation using the BOARI technique, modified by KUSS, was popularized in humans in 1954, and appears to be the most appropriate treatment for lesions of the lower ureter with significant loss of substance. Observation: We report in this work a case of iatrogenic ligation of the pelvic ureter on a single functional kidney (of fortuitous discovery) during gynecological surgery, having led to an Alteration of the General State (important Urinoma and collapse of the renal function) and treated by the surgical technique of BOARI KUSS at the urology department of the CHU Le Luxembourg. Follow-up and postoperative follow-up were excellent. Conclusion: Surgical repair of the ureter is very often indicated in cases of stenosis or iatrogenic lesions of the ureter. The BOARI KUSS technique is a good choice in cases of significant loss of substance due to injury to the lower ureter. Gynecological surgery is the main source of these lesions, and the prognosis of the treatment depends on how early the diagnosis is made, the anatomical condition of the ureter and the expertise of the surgical team.
