Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countri...Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countries.Patient concerns:A 26-year-old male complained of weakness,severe vomiting,and reduced breathlessness when lying on the left side.He had a history of pulmonary tuberculosis two years ago.Diagnosis:Symptomatic bradycardia in tuberculosis-related giant bullae.Interventions:The patient was recommended to undergo an elective bullectomy,but he decided not to proceed with the procedure.Atropine sulfate was administered to alleviate symptoms of bradycardia,while a standardized anti-tuberculosis regimen were started for the next six months.Outcomes:Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate,the patient achieved hemodynamic stability,opting against bullectomy despite residual symptoms of dyspnea.Subsequent six months of antituberculosis therapy notably alleviated symptoms without requiring bullectomy.Lessons:Increasing intrathoracic pressure can also be caused mechanically by giant bullae.Cardiac symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is addressed.In this case,symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention。展开更多
A 67-year-old man was referred for further evaluation of an abnormal chest roentgenogram. Computed tomography showed a 40 × 30 mm mass in the left upper lobe. A giant bulla occupying about two-thirds of the right...A 67-year-old man was referred for further evaluation of an abnormal chest roentgenogram. Computed tomography showed a 40 × 30 mm mass in the left upper lobe. A giant bulla occupying about two-thirds of the right thorax was found compressing the adjacent lung parenchyma, shifting the mediastinum to the left. The mass was a primary lung cancer, clinical T2aN0M0, stage IB. Preoperative respiratory function evaluation showed poor pulmonary function, with a forced expiratory volume in 1 second of 1070 ml (29.2% of predicted). Therefore, we first performed giant bullectomy by video-assisted thoracoscopic surgery. At 1 month after this operation, improvement of the forced expiratory volume in 1 second significantly to 2140 ml (80.1% of predicted) was observed. Therefore, we performed resection for the tumor. He was discharged after an uneventful postoperative course, and has remained in good condition for 6 months after the operation.展开更多
目的比较4种手术方法治疗重度慢性阻塞性肺疾病伴肺大疱的临床疗效。方法回顾性选取2019年1月—2021年12月广元市第一人民医院心胸外科79例重度慢性阻塞性肺疾病伴肺大疱手术患者,根据切口类型不同为开胸组(n=12)、小切口组(n=15)、单孔...目的比较4种手术方法治疗重度慢性阻塞性肺疾病伴肺大疱的临床疗效。方法回顾性选取2019年1月—2021年12月广元市第一人民医院心胸外科79例重度慢性阻塞性肺疾病伴肺大疱手术患者,根据切口类型不同为开胸组(n=12)、小切口组(n=15)、单孔组(n=23)、两孔组(n=29),4组患者均施行单侧肺减容、肺大疱切除术。统计患者一般资料、手术时间、术中出血量、重症加强护理病房(intensive care unit,ICU)时间、术后总引流量、胸管留置时间、住院时间、不良事件发生率、肺功能、血气指标、6 min步行距离并进行对比分析。结果79例患者无围术期死亡,术后2个月开胸组因严重的肺部感染合并呼吸衰竭死亡1例。4组患者手术时间、死亡发生率比较,差异无统计学意义(P>0.05)。单孔和两孔胸腔镜组术中出血量、ICU时间、术后总引流量、胸管留置时间、住院时间、不良事件发生率较小切口及开胸手术比较,差异有统计学意义(P<0.05)。4组患者术后7 d第1秒用力呼气容积占预计值百分比(63.55±25.15)、(61.69±24.53)、(64.02±24.22)、(64.20±30.09)较术前比较(44.48±12.55)、(42.01±13.15)、(43.89±13.21)、(42.59±14.76)均明显改善,差异有统计学意义(P<0.05)。结论单孔和两孔明显优于小切口及开胸手术,术后患者呼吸困难及生活质量明显改善。是一种创伤小、有效、可靠和安全的手术技术,可以让患者在几年内获得更好的生活质量,更适合肺功能差的患者。展开更多
文摘Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countries.Patient concerns:A 26-year-old male complained of weakness,severe vomiting,and reduced breathlessness when lying on the left side.He had a history of pulmonary tuberculosis two years ago.Diagnosis:Symptomatic bradycardia in tuberculosis-related giant bullae.Interventions:The patient was recommended to undergo an elective bullectomy,but he decided not to proceed with the procedure.Atropine sulfate was administered to alleviate symptoms of bradycardia,while a standardized anti-tuberculosis regimen were started for the next six months.Outcomes:Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate,the patient achieved hemodynamic stability,opting against bullectomy despite residual symptoms of dyspnea.Subsequent six months of antituberculosis therapy notably alleviated symptoms without requiring bullectomy.Lessons:Increasing intrathoracic pressure can also be caused mechanically by giant bullae.Cardiac symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is addressed.In this case,symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention。
文摘A 67-year-old man was referred for further evaluation of an abnormal chest roentgenogram. Computed tomography showed a 40 × 30 mm mass in the left upper lobe. A giant bulla occupying about two-thirds of the right thorax was found compressing the adjacent lung parenchyma, shifting the mediastinum to the left. The mass was a primary lung cancer, clinical T2aN0M0, stage IB. Preoperative respiratory function evaluation showed poor pulmonary function, with a forced expiratory volume in 1 second of 1070 ml (29.2% of predicted). Therefore, we first performed giant bullectomy by video-assisted thoracoscopic surgery. At 1 month after this operation, improvement of the forced expiratory volume in 1 second significantly to 2140 ml (80.1% of predicted) was observed. Therefore, we performed resection for the tumor. He was discharged after an uneventful postoperative course, and has remained in good condition for 6 months after the operation.
文摘目的比较4种手术方法治疗重度慢性阻塞性肺疾病伴肺大疱的临床疗效。方法回顾性选取2019年1月—2021年12月广元市第一人民医院心胸外科79例重度慢性阻塞性肺疾病伴肺大疱手术患者,根据切口类型不同为开胸组(n=12)、小切口组(n=15)、单孔组(n=23)、两孔组(n=29),4组患者均施行单侧肺减容、肺大疱切除术。统计患者一般资料、手术时间、术中出血量、重症加强护理病房(intensive care unit,ICU)时间、术后总引流量、胸管留置时间、住院时间、不良事件发生率、肺功能、血气指标、6 min步行距离并进行对比分析。结果79例患者无围术期死亡,术后2个月开胸组因严重的肺部感染合并呼吸衰竭死亡1例。4组患者手术时间、死亡发生率比较,差异无统计学意义(P>0.05)。单孔和两孔胸腔镜组术中出血量、ICU时间、术后总引流量、胸管留置时间、住院时间、不良事件发生率较小切口及开胸手术比较,差异有统计学意义(P<0.05)。4组患者术后7 d第1秒用力呼气容积占预计值百分比(63.55±25.15)、(61.69±24.53)、(64.02±24.22)、(64.20±30.09)较术前比较(44.48±12.55)、(42.01±13.15)、(43.89±13.21)、(42.59±14.76)均明显改善,差异有统计学意义(P<0.05)。结论单孔和两孔明显优于小切口及开胸手术,术后患者呼吸困难及生活质量明显改善。是一种创伤小、有效、可靠和安全的手术技术,可以让患者在几年内获得更好的生活质量,更适合肺功能差的患者。
