Endoscopic characteristics of small intestinal malignant tumors observed by balloon-assisted enteroscopy

BACKGROUND Capsule endoscopy and balloon-assisted enteroscopy(BAE) enable visualization of rare small bowel conditions such as small intestinal malignant tumors.However,details of the endoscopic characteristics of small intestinal malignant tumors are still unknown.AIM To elucidate the endoscopic characteristics of small intestinal malignant tumors.METHODS From March 2005 to February 2017,1329 BAE procedures were performed at Keio University Hospital. Of these procedures,malignant tumors were classified into three groups,Group 1: epithelial tumors including primary small intestinal cancer,metastatic small intestinal cancer,and direct small intestinal invasion by an adjacent organ cancer; Group 2: small intestinal malignant lymphoma; and Group 3,small intestinal gastrointestinal stromal tumors. We systematically collected clinical and endoscopic data from patients' medical records to determine the endoscopic characteristics for each group.RESULTS The number of patients in each group was 16(Group 1),23(Group 2),and 6(Group 3),and the percentage of solitary tumors was 100%,43.5%,and 100%,respectively(P < 0.001). Patients' clinical background parameters including age,symptoms,and laboratory data were not significantly different between the groups. Seventy-five percent of epithelial tumors(Group 1) were located in the upper small intestine(duodenum and ileum),and approximately 70% of gastrointestinal stromal tumors(Group 3) were located in the jejunum. Solitary protruding or mass-type tumors were not seen in malignant lymphoma(Group2)(P < 0.001). Stenosis was seen more often in Group 1,(68.8%,27.3%,and 0%;Group 1,2,and 3,respectively; P = 0.004). Enlarged white villi inside and/or surrounding the tumor were seen in 12.5%,54.5%,and 0% in Group 1,2,and 3,respectively(P = 0.001).CONCLUSION The differential diagnosis of small intestinal malignant tumors could be tentatively made based on BAE findings.

Balloon-assisted enteroscopy for suspected Meckel's diverticulum and indefinite diagnostic imaging workup

Meckel&rsquo;s diverticulum (MD) is estimated to affect 1%-2% of the general population, and it represents a clinically silent finding of a congenital anomaly in up to 85% of the cases. In adults, MD may cause symptoms, such as overt occult lower gastrointestinal bleeding. The diagnostic imaging workup includes computed tomography scan, magnetic resonance imaging enterography, technetium 99m scintigraphy (99mTc) using either labeled red blood cells or pertechnetate (known as the Meckel&rsquo;s scan) and angiography. The preoperative detection rate of MD in adults is low, and many patients ultimately undergo exploratory laparoscopy. More recently, however, endoscopic identification of MD has been possible with the use of balloon-assisted enteroscopy via direct luminal access, which also provides visualization of the diverticular ostium. The aim of this study was to review the diagnosis by double-balloon enteroscopy of 4 adults with symptomatic MD but who had negative diagnostic imaging workups. These cases indicate that balloon-assisted enteroscopy is a valuable diagnostic method and should be considered in adult patients who have suspected MD and indefinite findings on diagnostic imaging workup, including negative Meckel&rsquo;s scan.

Device-assisted enteroscopy: Are we ready to dismiss the spiral?

Motorized spiral enteroscopy(MSE)is the latest advance in device-assisted enteroscopy.Adverse events related to MSE were discussed in a recent large systematic review and meta-analysis and were directly compared with those of balloon enteroscopy in a case-matched study and a randomized controlled trial.Following the real-life application of MSE,an unexpected safety issue emerged regarding esophageal injury and the technique has been withdrawn from the global market,despite encouraging results in terms of diagnostic and therapeutic yield.We conducted an Italian multicenter real-life prospective study,which was prematurely terminated after the withdrawal of MSE from the market.The primary goals were the evaluation of MSE performance(both diagnostic and therapeutic)and its safety in routine endoscopic practice,particularly in the early phase of introduction in the endoscopic unit.A subanalysis,which involved patients who underwent MSE after unsuccessful balloon enteroscopy,demonstrated,for the first time,the promising performance of MSE as a rescue procedure.Given its remarkable performance in clinical practice and its potential role as a backup technique following a previously failed enteroscopy,it may be more appropriate to refine and enhance MSE in the future rather than completely abandoning it.

Motorized spiral enteroscopy:A cautious step forward in technological innovation

With the continuous advancement in medical technology,endoscopy has gained significant attention as a crucial diagnostic tool.The introduction of motorized spiral enteroscopy(MSE)represents a significant advancement in the diagnosis and treatment of small bowel diseases.While there are safety concerns and a high reliance on the operator’s skills,MSE should not be disregarded entirely.Instead,it should be considered as a supplementary endoscopic technique,particularly in situations where conventional endoscopy proves ineffective.Through continuous research and technical optimization,MSE has the potential to become an im-portant addition to the endoscopy toolbox in the future.We call on colleagues in the industry to work together to promote the improvement of MSE technology through continuous research and practice,with the aim to bring out its unique value in endoscopy while ensuring patient safety.

Endoscopic treatment of biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants: Lessons learned from single-balloon enteroscopy-assisted ERCP

Background: Endoscopic treatment of biliopancreatic pathology is challenging due to surgically altered anatomy after Whipple's pancreaticoduodenectomy. This study aimed to evaluate the feasibility and safety of single-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography(SBE-ERCP) to treat biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants. Methods: We retrospectively analyzed 106 SBE-ERCP procedures in 46 patients with Whipple's variants. Technical and clinical success rates and adverse events were evaluated. Results: Biliary SBE-ERCP was performed in 34 patients and pancreatic SBE-ERCP in 17, including 5 with both indications. From a total of 106 SBE-ERCP procedures, 76 were biliary indication with technical success rate of 68/76(90%) procedures and clinical success rate of 30/34(88%) patients. Mild adverse event rate was 8/76(11%), without serious adverse events. From a total of 106 SBE-ERCP procedures, 30 were pancreatic indication with technical success rate of 24/30(80%) procedures( P = 0.194 vs. biliary SBEERCP) and clinical success rate of 11/17(65%) patients( P = 0.016 vs. biliary SBE-ERCP). Mild adverse event rate was 6/30(20%)( P = 0.194 vs. biliary SBE-ERCP), without serious adverse events. After SBE-ERCP failure, endoscopic ultrasound-guided drainage, percutaneous drainage and redo surgery were alternative therapeutic options. Conclusions: Biliopancreatic pathology after Whipple's pancreaticoduodenectomy variants can be treated using SBE-ERCP without serious adverse events. Technical and clinical success rates are high for biliary indications, whereas clinical success rate of pancreatic indications is significantly lower. SBE-ERCP can be considered as first-line treatment option in this patient group with surgically altered anatomy.

Balloon-assisted endoscopic submucosal dissection for treating small intestinal lipomas:Report of two cases

BACKGROUND Most small intestinal lipomas are treated surgically,and some require repeated surgeries for multiple lipomas.However,application of endoscopic submucosal dissection(ESD)technology in the deep small intestine is rarely reported owing to the special anatomical structure of the small intestine,medical equipment limitations,and the lack of relevant experience among endoscopists.CASE SUMMARY Two patients with small intestinal lipomas treated at the Air Force Medical Center from November 2015 to September 2019 were selected to undergo balloonassisted ESD to treat the lipomas and explore the technical feasibility and safety of ESD for treating small intestinal lipomas.The two patients successfully underwent balloon-assisted ESD to treat four small intestinal lipomas,with a complete resection rate of 100%(4/4),without intraoperative or postoperative bleeding,perforation,or other complications.After 3-6 mo of postoperative follow-up,the clinical symptoms caused by the lipomas were significantly relieved or disappeared after treatment.CONCLUSION Balloon-assisted ESD is a safe and reliable new method for treating deep intestinal lipomas and shows good clinical feasibility.

右美托咪定辅助全身麻醉对老年无痛肠镜检查患者血流动力学及认知功能的影响

目的探讨右美托咪定(DEX)辅助全身麻醉对老年无痛肠镜检查患者血流动力学及认知功能的影响。方法将2020年7月至2022年2月在焦作市第二人民医院门诊手术室行无痛肠镜检查的老年患者180例,根据随机数字表法分为对照组(n=90)和观察组(n=90)。对照组患者给予常规全身麻醉(舒芬太尼+丙泊酚麻醉诱导,丙泊酚麻醉维持);观察组患者在术前准备后加用DEX辅助全身麻醉。比较2组患者的血流动力学指标[平均动脉压(MAP)、心率(HR)]、全麻用药量、苏醒时间、认知功能[简易精神状况检查量表(MMSE)]评分、不良反应发生率。结果2组患者麻醉前(T0)各项指标的差异均无统计学意义(P>0.05);与T0时比较,麻醉10 min后(T1)、肠镜达回盲部(T2)、检查后退镜(T3)、术后10 min(T4)时两组患者的MAP、HR均显著降低,但观察组患者在T1、T2、T3、T4时的MAP、HR均显著高于对照组(P<0.05)。与对照组比较,观察组患者的全麻用药量显著降低,苏醒时间显著缩短,术后1、2、3 d的MMSE评分显著升高,认知功能障碍发生率及不良反应发生率均显著降低(P<0.05)。结论DEX可有效改善老年无痛肠镜检查患者的血流动力学及认知功能,减少全麻用药量,缩短患者苏醒时间,且安全性较好。

疑似小肠出血患者双气囊小肠镜全小肠对接检查的临床研究

背景:双气囊小肠镜(DBE)全小肠对接检查在疑似小肠出血(SSBB)患者诊治中发挥重要作用。目的:调查SSBB患者DBE全小肠对接检查情况并分析其临床特征。方法:纳入2018年6月—2023年4月安徽省蚌埠市第三人民医院和安徽医科大学第一附属医院需行DBE对接检查的94例SSBB患者,并分析其临床特征。结果:共54例SSBB患者完成DBE全小肠对接检查,对接成功率为57.4%。因发现出血病变而中止对接检查者10例(10.6%),肠腔狭窄而中止对接检查者5例(5.3%),操作中出现进镜困难而中止对接检查者25例(26.5%)。SSBB患者DBE全小肠对接率与不同对接时间、医师既往小肠镜操作例数有关(P<0.05),而与患者性别、年龄、出血表现形式、烟酒嗜好、营养风险、腹部手术史、肛周病变、自身免疫病、术前贫血、术前白蛋白水平、进镜途径均无关(P>0.05)。ROC曲线结果显示,先进镜深度的截断值为385 cm时,评估SSBB患者完成全小肠对接检查的敏感性为72.2%,特异性为77.5%,曲线下面积为0.800(95%CI:0.705~0.875,P<0.001)。结论:SSBB患者DBE全小肠对接率与不同对接时间、医师既往小肠镜操作例数有关。先进镜深度达到385 cm以上,80%的SSBB患者有望实现全小肠对接检查。

小肠镜联合探头式共聚焦激光显微内镜对小肠疾病的观察研究

目的 探索小肠疾病在探头式共聚焦激光显微内镜(pCLE)图像中的特有表现,以揭示其在小肠疾病实时诊断中的潜在应用价值。方法 纳入2023年2月~2023年6月我院接受小肠镜和pCLE检查的小肠疾病患者48例。结合组织病理学图片特征,分析小肠疾病在pCLE图像中的特殊征象。结果 回顾性分析采集的pCLE图像,可清晰观察到与小肠疾病病理诊断相符的一系列特殊征象,包括但不限于上皮细胞脱落、杯状细胞增多、腺体间距增宽、上皮连续性中断或缺失、腺体结构破坏、隐窝结构异常、荧光素钠渗漏、血管增粗迂曲等。结论 pCLE技术在小肠疾病的诊断中与病理特征具有一致性,其图像中观察到的特有表现可为小肠疾病的实时诊断提供依据,有一定的应用潜力。

老年病人经肛双气囊小肠镜进镜效率及其影响因素研究

目的 探讨老年病人经肛双气囊小肠镜检查(DBE)的进镜效率及影响因素。方法 纳入2022年3月至2023年10月在南京医科大学第一附属医院老年内镜中心行经肛DBE的180例60岁以上的老年病人,收集其一般资料,采用渥太华肠道准备评分(OBPS)评估病人肠道准备质量,统计经肛DBE的进镜深度及操作时间,计算进镜效率,根据进镜效率分为高效组和低效组,分析进镜效率的影响因素。结果 单因素分析显示,手术部位、息肉或憩室疾病、盲肠插管时间(CIT)与经肛DBE进镜效率相关。多因素Logistic回归分析显示,息肉等病史、手术部位及CIT是经肛DBE进镜效率的独立影响因素,有下腹部手术史的病人进镜效率较低。结论 下腹部手术史、息肉或憩室疾病、CIT长会降低老年病人经肛DBE的进镜效率。

双气囊小肠镜在疑似小肠出血中的临床应用:一项单中心回顾性队列研究

目的探讨近10年双气囊小肠镜(double-balloon enteroscopy,DBE)检查疑似小肠出血(suspected small bowel bleeding,SSBB)的适应证、诊断率及不良事件的变化。方法回顾性分析某三级医院第1阶段(较早阶段,2013年9月至2018年8月)和第2阶段(较晚阶段,2018年9月至2023年8月)完成DBE检查患者的临床及内镜资料。结果共纳入451例患者(第1阶段214例,第2阶段237例)。第2阶段中从最后一次出血到DBE检查的时间间隔比第1阶段更短[(5.8±1.3)d vs(6.6±1.8),P<0.001]。第2阶段显性出血比例和全小肠检查率(total enteroscopy rate,TER)均高于第1阶段(89.9%vs 79.9%,P<0.05;88.4%vs 59.0%,P<0.001)。肿瘤(26.4%)、克罗恩病(15.7%)和憩室(12.6%)是SSBB的前三大常见病因。第2阶段血管病变的诊断率和比例高于第1阶段(85.7%vs 66.8%,P<0.01;13.5%vs 3.7%,P<0.05)。两阶段检查相关不良事件发生率差异无统计学意义(2.1%vs 3.7%,P>0.05)。结论DBE诊断SSBB有效、安全。随着时间推移,显性出血作为DBE检查的适应症变得越来越普遍。与第1阶段相比,第2阶段DBE的诊断率有所提高,并发症发生率无显著差异。

基于Web of Science数据库中小肠镜研究的文献计量与可视化分析

目的分析全球小肠镜领域研究现状和研究热点,为小肠镜领域相关研究提供参考依据。方法限定发表年份为“1998-2022”、语言为“English”、文献类型为“Article”,于2022年9月25日在Web of Science(WoS)数据库中采用主题词“Enteroscopy”进行检索;采用VOSviewer 1.6.17软件和文献计量在线分析平台(https://bibliometric.com)对纳入文献的发文国家、机构、作者及关键词等进行分析,并绘制相应可视化知识图谱。结果共有2204篇论著纳入分析。小肠镜领域发文量前3位的国家分别是美国、日本和中国;美国梅奥诊所(69篇)、巴黎公共医疗救助机构(62篇)、法国Udice研究型大学(62篇)占研究机构发文量前3位;小肠镜领域发文量前3位的作者分别是Yamamoto(49篇)、Nakamura(42篇)和Tanaka(40篇);Yamamoto(1688次)、Yano(1514次)和Tanaka(947次)为该领域高被引作者;关键词共现网络中胶囊内镜(出现625次)、小肠镜(出现555次)、双气囊小肠镜(出现516次)、诊断(出现424次)等为小肠镜领域高频词。结论在过去20多年中,小肠镜领域的研究发展迅猛,中国在全球小肠镜领域的地位也逐步提高。胶囊内镜和小肠镜用于小肠疾病的诊治一直是小肠镜领域的研究热点。

Application of novel magnified single balloon enteroscopy for a patient with Cronkhite-Canada syndrome

We present a case of Cronkhite-Canada syndrome(CCS) in which the entire intestine was observed using a prototype of magnifying single-balloon enteroscope(SIF Y-0007, Olympus). CCS is a rare, non-familial gastrointestinal polyposis with ectodermal abnormalities. To our knowledge, this is the first report showing magnified intestinal lesions of CCS. A 73-year-old female visited our hospital with complaints of diarrhea and dysgeusia. The blood test showed mild anemia and hypoalbuminemia. The esophagogastroduodenoscopy and colonoscopy revealed diffuse and reddened sessile to semi-pedunculated polyps, resulting in the diagnosis of CCS. In addition to the findings of conventional balloon-assisted enteroscopy or capsule endoscopy, magnifying observation revealed tiny granular structures, non-uniformity of the villus, irregular caliber of the loop-like capillaries, scattered white spots in the villous tip, and patchy redness of the villus. Histologically, the scattered white spots and patchy redness of the villus reflect lymphangiectasia and bleeding to interstitium, respectively.

气囊辅助式小肠镜在诊断Meckel憩室中的应用价值

目的:探讨气囊辅助式小肠镜及其他不同检查方法对小肠Meckel憩室的诊断价值。方法:回顾性分析2010年1月—2023年12月于南京医科大学第一附属医院确诊为小肠Meckel憩室的87例患者,收集患者的一般资料、临床表现、诊断方法、治疗及病理结果等资料,总结归纳临床特征,比较气囊辅助式小肠镜与其他检查方法对小肠Meckel憩室的诊断价值。结果:87例小肠Meckel憩室患者中,55例合并消化道出血、肠梗阻、憩室炎、肠穿孔等并发症。与无并发症患者相比,伴并发症患者中位年龄较小(P=0.003),憩室直径更长[(5.2±2.6)cm vs.(3.3±1.4)cm,P=0.001],开口更宽[(2.4±1.1)cm vs.(1.6±0.7)cm,P=0.002],手术率也更高(89.1%vs.56.3%,P <0.001)。不同检查方法的诊断灵敏度分别为:气囊辅助式小肠镜94.4%,核素显像(异位胃黏膜显像)58.3%,胶囊内镜30.0%,小肠CT 9.4%,腹部CT 8.2%,数字减影血管造影0。结论:年轻患者、憩室直径长、开口宽的小肠Meckel憩室更易合并憩室炎、穿孔、出血、梗阻等并发症。气囊辅助式小肠镜对Meckel憩室的术前诊断价值最高,应作为疑诊小肠Meckel憩室患者的首选检查方法。

基于多靶点粪便FIT-DNA联合检测技术的结直肠癌早筛应用研究

目的评价多靶点粪便FIT-DNA联合检测技术在结直肠癌早期筛查中的效果并进一步分析其应用前景。方法选取内蒙古医科大学附属医院就诊人群,每位受试者分别行血清肿瘤标志物检测、多靶点粪便FIT-DNA联合检测、肠镜检查,以接受多靶点粪便FIT-DNA联合检测人群为实验组,以接受肠镜检查及血清肿瘤标志物检测人群为对照组,以病理结果为金标准,评价新型粪便分子检测技术对于结直肠癌筛查的效果,对筛出的阳性人群给予及时干预。结果共分析了115例患者。血清肿瘤标志物检测敏感度63.2%(43/68),特异度74.5%(35/47);肠镜检查敏感度97.1%(66/68),特异度80.7%(38/47);而多靶点粪便FIT-DNA联合检测敏感度89.7%(61/68),特异度87.2%(41/47)。多靶点粪便FIT-DNA联合检测敏感度、特异度等均优于血清肿瘤标志物检测,敏感度虽低于肠镜检查,但相较肠镜检查操作简单,可居家自测。

Treatment of hemolymphangioma by robotic surgery: A case report

BACKGROUND Hemolymphangioma of the jejunum is rare and lacks clinical specificity,and can manifest as gastrointestinal bleeding,abdominal pain,and intestinal obstruction.Computed tomography,magnetic resonance imaging,and other examinations show certain characteristics of the disease,but lack accuracy.Although capsule endoscopy and enteroscopy make up for this deficiency,the diagnosis also still re-quires pathology.CASE SUMMARY A male patient was admitted to the hospital due to abdominal distension and abdominal pain,but a specific diagnosis by computed tomography examination was not obtained.Partial resection of the small intestine was performed by robotic surgery,and postoperative pathological biopsy confirmed the diagnosis of hemo-lymphangioma.No recurrence in the follow-up examination was observed.CONCLUSION Robotic surgery is an effective way to treat hemolymphangioma through minima-lly invasive techniques under the concept of rapid rehabilitation.

黄河三角洲地区135例小肠溃疡的临床分析

目的:总结黄河三角洲地区小肠溃疡患者的病因构成、内镜表现及临床特点,为临床诊治提供依据。方法:回顾性分析2020年5月1日—2023年3月1日于滨州医学院附属医院经小肠镜或胶囊内镜首次诊断为小肠溃疡的135例患者的临床资料。结果:黄河三角洲地区小肠溃疡多发于40~59岁,男女比例为1.55︰1。小肠溃疡的病因主要以克罗恩病最多见,临床表现多为腹痛、腹泻、便血和黑便,影像学检查特点为小肠管壁增厚、肠系膜淋巴结肿大及小肠管腔狭窄。小肠镜及胶囊内镜检出率分别为26.83%及8.67%,常见溃疡部位为回肠、回盲部和空肠,内镜下溃疡特点以不规则样、纵行、环形、节段性为主,病理改变主要是黏膜慢性炎和伴炎细胞浸润。结论:小肠溃疡的病因复杂,临床特点缺乏特异性,小肠镜及胶囊内镜有助于小肠溃疡的诊断,但内镜下的表现常有重叠,病理活检在疾病的诊断中仍具有一定的局限性,应进一步探究CT等辅助检查在小肠溃疡诊断及鉴别诊断中的作用。

双气囊小肠镜对小肠出血的临床诊治价值

目的探讨双气囊小肠镜对小肠出血性疾病的临床诊疗价值。方法回顾性分析汕头市中心医院内镜中心2019年8月至2023年5月因小肠出血行双气囊小肠镜检查87例患者的临床资料,分析双气囊小肠镜对小肠出血病因的诊疗情况。结果87例小肠出血患者共进行117次双气囊小肠镜检查,其中,单侧经口进镜29次,单侧经肛进镜28次,30例患者同时进行经口经肛双侧进镜检查,经口进镜深度大于经肛进镜,且经口进镜检查时间少于经肛进镜检查时间。双气囊小肠镜诊断率为83.91%,病理诊断准确率为83.78%。小肠肿瘤是本研究中导致小肠出血的主要病因,小肠间质瘤是小肠肿瘤中最常见的病理类型,年龄>40岁人群中出现小肠肿瘤的频率要高于年龄≤40岁人群,差异有统计学意义(P<0.05)。克罗恩病发生在回肠的频率高于空肠,年龄≤40岁人群中发生克罗恩病的频率高于年龄>40岁人群,差异均有统计学意义(P<0.05)。共有14例小肠出血患者经双气囊小肠镜行内镜下止血成功,所有患者术中均未出现消化道穿孔、严重出血等并发症。结论双气囊小肠镜对小肠出血性疾病具有较高的诊断价值,必要时可进行内镜下治疗,是一种安全、可靠、实用的诊疗方法。

2023年小肠疾病诊治进展

2023年,小肠疾病领域取得了多项重要发现和突破。基于数据库的小肠肿瘤全球流行病学研究首次发布。研究显示,2020年全球的小肠癌发病率为0.6/10万,较2010年至2020年的全球平均小肠癌发病率呈上升趋势(不同大洲平均年变化百分比为2.20%~21.67%)。小肠癌的发病负担存在地域差异性,其中北美最高,年龄标化发病率为1.4/10万人。我国男性的小肠癌发病率为0.32/10万人,女性为1.95/10万人。小肠癌发病危险因素(β为0.008~0.198;OR为1.07~10.01)包括较高的人类发展指数、国内生产总值;存在吸烟、饮酒习惯;缺乏运动、肥胖;存在糖尿病、脂代谢紊乱及炎症性肠病病史。在治疗方面,舒林达克和厄洛替尼联合治疗可有效减少家族性腺瘤息肉病患者的息肉负荷。对于小肠克罗恩病,软件方面,人工智能辅助内镜识别被证实可减少漏诊率,提高医疗质量;硬件方面,电动螺旋小肠镜是一把双刃剑,虽然具有更高的全小肠检查率,但在安全性得到充分保障前,仍无法大规模临床推广;药物方面,随着对疾病发病机制的深入了解,针对炎症过程的靶向治疗逐渐成为研究的热点,小分子制剂如乌帕替尼、filgotinib临床数据不断积累;外科方面,最新证据支持新诊断的回肠或回结肠克罗恩病患者接受回结肠切除术作为一线治疗的疗效不劣于肿瘤坏死因子α单抗治疗。小肠出血的诊治也在不断进步,沙利度胺作为突破性药物用于治疗毛细血管畸形所致小肠出血,为广大患者带去福音。此外,小肠梗阻的外科治疗理念逐步更新,通过评分体系,可预测小肠梗阻患者适宜接受外科手术切除或接受内科保守治疗。未来随着医疗技术、理念和人工智能的不断发展和创新,小肠疾病的诊治将会更加精准和高效。

不同时间口服西甲硅油祛泡剂对肠镜检查前肠道准备的效果影响

目的 探讨不同时间点服用西甲硅油在肠镜检查前肠道准备中的作用。方法 选取2022年1月至12月于温州医科大学附属第一医院行肠镜检查的330例患者为研究对象,根据随机数字法将患者分为A、B、C三组,每组各110例。A组患者于肠镜检查前1h服用西甲硅油,B组于检查前2h服用西甲硅油,C组于检查前4h服用西甲硅油。比较三组患者肠腔内的气泡量评分、生理盐水冲洗量及操作医生满意度。结果 三组间肠腔内的气泡含量、生理盐水冲洗量及操作医生满意度比较,差异均有统计学意义(P<0.05),但B组最好。结论 在行肠镜检查前2h口服西甲硅油,可明显减少肠腔内的气泡,提升肠镜检查观察视野的清晰度,提高操作医生的满意度。