BACKGROUND Diabetic ketoacidosis(DKA)is a serious complication of type 1 diabetes mellitus(T1DM).Very rarely does DKA lead to cerebral edema,and it is even rarer for it to result in cerebral infarction.Bilateral inter...BACKGROUND Diabetic ketoacidosis(DKA)is a serious complication of type 1 diabetes mellitus(T1DM).Very rarely does DKA lead to cerebral edema,and it is even rarer for it to result in cerebral infarction.Bilateral internal carotid artery occlusion(BICAO)is also rare and can cause fatal stroke.Moreover,case reports about acute cerebral infarction throughout both internal carotid arteries with simultaneous BICAO are very scarce.In this study,we present a patient with BICAO,T1DM,hypertension,and hyperlipidemia,who had a catastrophic bilateral cerebral infarction after a DKA episode.We briefly introduce BICAO and the mechanisms by which DKA results in cerebral infarction.CASE SUMMARY A 41-year-old woman presented with ischemic stroke that took place 3 mo prior over the left corona radiata,bilateral frontal lobe,and parietal lobe with right hemiplegia and Broca’s aphasia.She had a history of hypertension for 5 years,hyperlipidemia for 4 years,hyperthyroidism for 3 years,and T1DM for 31 years.The first brain magnetic resonance imaging not only revealed the aforementioned ischemic lesions but also bilateral internal carotid artery occlusion.She was admitted to our ward for rehabilitation due to prior stroke sequalae.DKA took place on hospital day 2.On hospital day 6,she had a new massive infarction over the bilateral anterior cerebral artery and middle cerebral artery territory.After weeks of aggressive treatment,she remained in a coma and on mechanical ventilation due to respiratory failure.After discussion with her family,compassionate extubation was performed on hospital day 29 and she died.CONCLUSION DKA can lead to cerebral infarction due to several mechanisms.In people with existing BICAO and several stroke risk factors such as hypertension, T1DM,hyperlipidemia, DKA has the potential to cause more serious ischemic strokes.展开更多
BACKGROUND Cesarean scar pregnancy(CSP)is rare but may result in uterine rupture during pregnancy or massive hemorrhage during abortion procedures.Awareness of this condition is increasing,and most patients with CSP a...BACKGROUND Cesarean scar pregnancy(CSP)is rare but may result in uterine rupture during pregnancy or massive hemorrhage during abortion procedures.Awareness of this condition is increasing,and most patients with CSP are now diagnosed early and can be managed safely.However,some atypical patients are misdiagnosed,and their surgical risks are underestimated,increasing the risk of fatal hemorrhage.CASE SUMMARY A 27-year-old Asian woman visited our institution because of abnormal pregnancy,and she was diagnosed with a hydatidiform mole through transvaginal ultrasound(TVS).Under hysteroscopy,a large amount of placental tissue was found in the scar of the lower uterine segment,and a sudden massive hemorrhage occurred during the removal process.The bilateral internal iliac arteries were temporarily blocked under laparoscopy,and scar resection and repair were rapidly performed.She was discharged in good condition 5 d after the operation.CONCLUSION Although TVS is widely used in the diagnosis of CSP,delays in the diagnosis of atypical CSP remain.Surgical treatment following internal iliac artery temporary occlusion may be an appropriate management method for unanticipated massive hemorrhage during CSP surgery.展开更多
目的:探讨髂内动脉球囊预置阻断术在植入型凶险性前置胎盘中的临床价值。方法:选取2021年7月—2024年1月阳江市人民医院收治的60例植入型凶险性前置胎盘患者。根据随机数表法将其分为对照组与观察组,各30例。两组均行剖宫产,对照组应用...目的:探讨髂内动脉球囊预置阻断术在植入型凶险性前置胎盘中的临床价值。方法:选取2021年7月—2024年1月阳江市人民医院收治的60例植入型凶险性前置胎盘患者。根据随机数表法将其分为对照组与观察组,各30例。两组均行剖宫产,对照组应用常规止血措施,观察组应用双侧髂内动脉球囊预置术。比较两组围手术期指标、新生儿情况、子宫切除率、并发症。结果:观察组术中出血量少于对照组,手术时间与住院时间均短于对照组,差异有统计学意义(P<0.05)。两组新生儿出生1 min、5 min、10 min Apgar评分比较,差异无统计学意义(P>0.05)。观察组子宫切除率、并发症发生率均低于对照组,差异有统计学意义(P<0.05)。结论:双侧髂内动脉球囊预置术应用于植入型凶险性前置胎盘患者中效果显著,能够减少产妇术中出血量,降低大出血风险,缩短手术时间和住院时间,降低患者子宫切除率与术后并发症发生率。展开更多
目的采用meta分析方法对比远端腹主动脉球囊阻断和双侧髂内动脉球囊阻断在辅助凶险型前置胎盘(PPP)患者剖宫产术的安全性和有效性。方法计算机系统检索中国知网、万方和维普数据库并手工检索PPP预置球囊阻断治疗相关文献,检索时限均自...目的采用meta分析方法对比远端腹主动脉球囊阻断和双侧髂内动脉球囊阻断在辅助凶险型前置胎盘(PPP)患者剖宫产术的安全性和有效性。方法计算机系统检索中国知网、万方和维普数据库并手工检索PPP预置球囊阻断治疗相关文献,检索时限均自建库至2018年8月30日。由2名独立评价者对纳入文献进行质量评价,采用Review Manager 5.0 for Mac软件进行meta分析。结果共有11篇文献纳入分析,结果显示腹主动脉球囊阻断组患者在术中胎儿射线接触量、手术时间、术中出血量、子宫切除率方面优于双侧髂总动脉球囊阻断组,OR(95%CI)分别为-2.57(-2.85^-2.29)、-13.28(-16.56^-10.00)、-0.35(-0.53^-0.17)、0.70(0.50~0.78),P值均<0.05。结论PPP患者剖宫产术中远端腹主动脉球囊阻断技术在术中胎儿射线接触量、总体手术时间、术中出血量和子宫切除率方面优于双侧髂内动脉球囊阻断技术,为临床治疗方式选择提供依据。展开更多
目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异...目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异体血输入,B组采用自体血输入,C组采用自体输血联合双侧髂内动脉球囊预置术。结果术中出血量(1600 mL vs 1500 mL vs 800 mL)、术后住院时间(7 d vs 7 d vs 6 d)和手术时间(107 min vs 104.50 min vs 77 min)C组均低于A、B 2组(P<0.05),A、B 2组比较无差异(P>0.05);C组输入自体血量低于B组(525.5 mL vs 261 mL,P<0.05)。C组异体红细胞的输入占比低于A组(22.22%vs 100.00%,P<0.0167);C组血浆的输入占比低于A、B 2组(18.50%vs 66.70%/18.50%vs 44.40%,P<0.0167);C组凝血功能障碍发生率低于A组(7.41%vs 25.93%,P<0.0167);C组子宫切除发生率低于A组(1.85%vs 16.67%,P<0.0167),A、B 2组比较无差异(16.67%vs 11.11%,P>0.0167)。结论在出血高危患者剖宫产术中采用回收式自体输血联合双侧髂内动脉球囊预置术效果理想,能明显减少术中失血量、术中自体血回输量、异体红细胞和血浆成分的输入量,同时减少手术时间和术后住院时间。此外,还改善凝血功能和子宫切除情况,有利于保障产妇的生命安全和促进早期康复,且一定程度保留患者生育能力,值得临床进一步推广。展开更多
文摘BACKGROUND Diabetic ketoacidosis(DKA)is a serious complication of type 1 diabetes mellitus(T1DM).Very rarely does DKA lead to cerebral edema,and it is even rarer for it to result in cerebral infarction.Bilateral internal carotid artery occlusion(BICAO)is also rare and can cause fatal stroke.Moreover,case reports about acute cerebral infarction throughout both internal carotid arteries with simultaneous BICAO are very scarce.In this study,we present a patient with BICAO,T1DM,hypertension,and hyperlipidemia,who had a catastrophic bilateral cerebral infarction after a DKA episode.We briefly introduce BICAO and the mechanisms by which DKA results in cerebral infarction.CASE SUMMARY A 41-year-old woman presented with ischemic stroke that took place 3 mo prior over the left corona radiata,bilateral frontal lobe,and parietal lobe with right hemiplegia and Broca’s aphasia.She had a history of hypertension for 5 years,hyperlipidemia for 4 years,hyperthyroidism for 3 years,and T1DM for 31 years.The first brain magnetic resonance imaging not only revealed the aforementioned ischemic lesions but also bilateral internal carotid artery occlusion.She was admitted to our ward for rehabilitation due to prior stroke sequalae.DKA took place on hospital day 2.On hospital day 6,she had a new massive infarction over the bilateral anterior cerebral artery and middle cerebral artery territory.After weeks of aggressive treatment,she remained in a coma and on mechanical ventilation due to respiratory failure.After discussion with her family,compassionate extubation was performed on hospital day 29 and she died.CONCLUSION DKA can lead to cerebral infarction due to several mechanisms.In people with existing BICAO and several stroke risk factors such as hypertension, T1DM,hyperlipidemia, DKA has the potential to cause more serious ischemic strokes.
基金Supported by Medical Health Science and Technology Project of Zhejiang Province,China,No.2020ZH003。
文摘BACKGROUND Cesarean scar pregnancy(CSP)is rare but may result in uterine rupture during pregnancy or massive hemorrhage during abortion procedures.Awareness of this condition is increasing,and most patients with CSP are now diagnosed early and can be managed safely.However,some atypical patients are misdiagnosed,and their surgical risks are underestimated,increasing the risk of fatal hemorrhage.CASE SUMMARY A 27-year-old Asian woman visited our institution because of abnormal pregnancy,and she was diagnosed with a hydatidiform mole through transvaginal ultrasound(TVS).Under hysteroscopy,a large amount of placental tissue was found in the scar of the lower uterine segment,and a sudden massive hemorrhage occurred during the removal process.The bilateral internal iliac arteries were temporarily blocked under laparoscopy,and scar resection and repair were rapidly performed.She was discharged in good condition 5 d after the operation.CONCLUSION Although TVS is widely used in the diagnosis of CSP,delays in the diagnosis of atypical CSP remain.Surgical treatment following internal iliac artery temporary occlusion may be an appropriate management method for unanticipated massive hemorrhage during CSP surgery.
文摘目的:探讨髂内动脉球囊预置阻断术在植入型凶险性前置胎盘中的临床价值。方法:选取2021年7月—2024年1月阳江市人民医院收治的60例植入型凶险性前置胎盘患者。根据随机数表法将其分为对照组与观察组,各30例。两组均行剖宫产,对照组应用常规止血措施,观察组应用双侧髂内动脉球囊预置术。比较两组围手术期指标、新生儿情况、子宫切除率、并发症。结果:观察组术中出血量少于对照组,手术时间与住院时间均短于对照组,差异有统计学意义(P<0.05)。两组新生儿出生1 min、5 min、10 min Apgar评分比较,差异无统计学意义(P>0.05)。观察组子宫切除率、并发症发生率均低于对照组,差异有统计学意义(P<0.05)。结论:双侧髂内动脉球囊预置术应用于植入型凶险性前置胎盘患者中效果显著,能够减少产妇术中出血量,降低大出血风险,缩短手术时间和住院时间,降低患者子宫切除率与术后并发症发生率。
文摘目的采用meta分析方法对比远端腹主动脉球囊阻断和双侧髂内动脉球囊阻断在辅助凶险型前置胎盘(PPP)患者剖宫产术的安全性和有效性。方法计算机系统检索中国知网、万方和维普数据库并手工检索PPP预置球囊阻断治疗相关文献,检索时限均自建库至2018年8月30日。由2名独立评价者对纳入文献进行质量评价,采用Review Manager 5.0 for Mac软件进行meta分析。结果共有11篇文献纳入分析,结果显示腹主动脉球囊阻断组患者在术中胎儿射线接触量、手术时间、术中出血量、子宫切除率方面优于双侧髂总动脉球囊阻断组,OR(95%CI)分别为-2.57(-2.85^-2.29)、-13.28(-16.56^-10.00)、-0.35(-0.53^-0.17)、0.70(0.50~0.78),P值均<0.05。结论PPP患者剖宫产术中远端腹主动脉球囊阻断技术在术中胎儿射线接触量、总体手术时间、术中出血量和子宫切除率方面优于双侧髂内动脉球囊阻断技术,为临床治疗方式选择提供依据。
文摘目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异体血输入,B组采用自体血输入,C组采用自体输血联合双侧髂内动脉球囊预置术。结果术中出血量(1600 mL vs 1500 mL vs 800 mL)、术后住院时间(7 d vs 7 d vs 6 d)和手术时间(107 min vs 104.50 min vs 77 min)C组均低于A、B 2组(P<0.05),A、B 2组比较无差异(P>0.05);C组输入自体血量低于B组(525.5 mL vs 261 mL,P<0.05)。C组异体红细胞的输入占比低于A组(22.22%vs 100.00%,P<0.0167);C组血浆的输入占比低于A、B 2组(18.50%vs 66.70%/18.50%vs 44.40%,P<0.0167);C组凝血功能障碍发生率低于A组(7.41%vs 25.93%,P<0.0167);C组子宫切除发生率低于A组(1.85%vs 16.67%,P<0.0167),A、B 2组比较无差异(16.67%vs 11.11%,P>0.0167)。结论在出血高危患者剖宫产术中采用回收式自体输血联合双侧髂内动脉球囊预置术效果理想,能明显减少术中失血量、术中自体血回输量、异体红细胞和血浆成分的输入量,同时减少手术时间和术后住院时间。此外,还改善凝血功能和子宫切除情况,有利于保障产妇的生命安全和促进早期康复,且一定程度保留患者生育能力,值得临床进一步推广。
