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广东惠州地区46例血红蛋白J-Bangkok的分子诊断及血液学特征分析 被引量:2
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作者 徐志邦 官志扬 +2 位作者 叶健翔 曾惠华 陈剑虹 《分子诊断与治疗杂志》 2023年第3期489-492,共4页
目的分析血红蛋白J-Bangkok(Hb J-Bangkok)患者的血液学特征。方法收集2015年10月至2021年3月于惠州市第一妇幼保健院就诊的患者共86645例,使用全自动毛细管电泳仪检测其外周血样本,对筛查出Hb J条带的样本行血细胞分析和DNA测序。采用... 目的分析血红蛋白J-Bangkok(Hb J-Bangkok)患者的血液学特征。方法收集2015年10月至2021年3月于惠州市第一妇幼保健院就诊的患者共86645例,使用全自动毛细管电泳仪检测其外周血样本,对筛查出Hb J条带的样本行血细胞分析和DNA测序。采用悬浮阵列技术检测α和β地中海贫血(简称地贫)基因。结果共检出46例Hb J-Bangkok(HBB:c.170G>A)患者,人群发生率为0.053%。单纯Hb J-Bangkok杂合子患者无血液学表型;Hb J-Bangkok合并SEA杂合子患者表现为轻型α地贫特征。首次报道了两例罕见类型,分别为Hb J-Bangkok合并Hb New York杂合子和Hb J-Bangkok合并SEA及βCD81杂合子。前者患者无明显血液学改变,其Hb J、Hb K和Hb A2分别为59.7%、39.5%和0.8%;后者患者表现为轻型α地贫特征。结论惠州地区人群Hb J-Bangkok发生率高,本研究有助于为疾病筛查提供参考数据以及完善惠州地区的地贫防控工作。 展开更多
关键词 血红蛋白J-bangkok 地中海贫血 血液学 基因型 DNA测序
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异常血红蛋白Hb J-Bangkok和Hb G-Coushatta的基因型与表型分析
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作者 裴元元 温丽娟 +1 位作者 冉健 魏凤香 《中国产前诊断杂志(电子版)》 2022年第4期28-31,共4页
目的分析2种β珠蛋白基因突变所致异常血红蛋白Hb J-Bangkok和Hb G-Coushatta的基因型及其血液学特征。方法收集深圳市龙岗区妇幼保健院2020年4至10月毛细管血红蛋白电泳检测出异常血红蛋白条带的病例4例,采用PCR-流式荧光杂交法及基因... 目的分析2种β珠蛋白基因突变所致异常血红蛋白Hb J-Bangkok和Hb G-Coushatta的基因型及其血液学特征。方法收集深圳市龙岗区妇幼保健院2020年4至10月毛细管血红蛋白电泳检测出异常血红蛋白条带的病例4例,采用PCR-流式荧光杂交法及基因测序方法进行基因诊断,对明确诊断的异常血红蛋白病例进行回顾性血液学参数分析。结果4个病例中检测到2种β珠蛋白基因突变,均为杂合子。3例为Hb J-Bangkok,血液学表型正常,血红蛋白电泳可见Hb A峰前Z12区有一条快速的异常血红蛋白;1例为Hb G-Coushatta,血液学表型未见异常,血红蛋白电泳Z(D)区有一条慢速异常血红蛋白。结论异常血红蛋白Hb J-Bangkok和Hb G-Coushatta的携带者均无小细胞低色素贫血的表现。毛细管电泳和基因测序技术联合应用,可以分辨和发现更多的异常血红蛋白。 展开更多
关键词 异常血红蛋白 Hb J-bangkok Hb G-Coushatta
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我国异常血红蛋白的研究3例Hb J Bangkok及其一级结构分析
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作者 王荷碧 蔡英林 +10 位作者 杨学庸 杨天楹 叶民刚 陈佩贞 周玉玲 林泽嬉 刘艳彤 高效曾 符清顺 谭谓泉 杨建中 《天津医药》 CAS 1984年第6期323-326,共4页
1981年本文部分作者在陕西商洛地区普查血红蛋白病时,在两个无关家系中发现一种泳动速度相同的快速血红蛋白,其电泳位置相当于J组,同年,又在福建龙岩地区发现一家系与上述相同之快速Hb。
关键词 Hb J bangkok ATPS 家系调查 嗜热菌蛋白酶 X型蛋白酶 异常血红蛋白
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Influence of Dimensions of UHMW-PE Protuberances on Sliding Resistance and Normal Adhesion of Bangkok Clay Soil to Biomimetic Plates 被引量:13
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作者 P.Soni V.M.Salokhe 《Journal of Bionic Engineering》 SCIE EI CSCD 2006年第2期63-71,共9页
A number of investigations into application of polymers for macro-morphological modification of tool surface have been carried out. These researches, with extensive stress on convex or domed protuberations as one of t... A number of investigations into application of polymers for macro-morphological modification of tool surface have been carried out. These researches, with extensive stress on convex or domed protuberations as one of the widely used construction units, have tried to harness benefits from using polymers in agriculture. Ultra high molecular weight polyethylene (UHMW-PE) has proved an emerging polymer in its application to reduce soil adhesion. This research was conducted to study the effect of shape (flat, semi-spherical, semi-oblate, semi short-prolate and semi long-prolate) and dimensions (base diameter and dome height) on sliding resistance and normal adhesion of biomimetic plates. To incorporate both shape and size, a dimensionless ratio of height to diameter (HDR) was introduced to characterize the effect of construction unit's physique. Experiments were conducted in Bangkok clay soil with dry ( 19.8% d.b.), sticky (36.9% d.b.) and flooded (60.1% d.b.) soil conditions respectively. Soil at sticky limit exhibited the highest sliding resistance (77.8 N) and normal adhesion (3 kPa to 7 kPa), whereas these values were 61.7 N and 〈0.2 kPa in dry, and 53.7 N and 0.5 kPa to 1.5 kPa in flooded soil conditions. Protuberances with HDR ≤ 0.5 lowered sliding resistance by 10% - 30% and the same reduced normal adhesion by 10% - 60%. The amount of reduction in both sliding resistance and normal adhesion was higher in flooded soil. Lighter normal loads obviously produced lesser resistance and adhesion. 展开更多
关键词 biomimetics UHMW-PE HDR convex domed protuberances sliding resistance normal adhesion bangkok clay soil
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Epidemiology of pediculosis capitis among schoolchildren in the eastern area of Bangkok,Thailand 被引量:3
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作者 Watcharawit Rassami Mayura Soonwera 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2012年第11期901-904,共4页
Objective:To determine the prevalence of infestation with head lice in primary schoolchildren in the eastern area of Bangkok,Thailand.Methods:The present study was to determine the head lice infestation(Pediculosis) l... Objective:To determine the prevalence of infestation with head lice in primary schoolchildren in the eastern area of Bangkok,Thailand.Methods:The present study was to determine the head lice infestation(Pediculosis) levels in primary schoolchildren,during May,2011 to July, 2011,A total of 3747 schoolchildren aged 5-12 years old from 12 selected primary school of Ladkrabang district,the eastern area of Bangkok were examined for head lice.Pediculosis was defined as the presence of at least on living adult,nymph and viable egg.Results:The overall head lice infestation rate was 23.32%and infestation rate was higher in girls(47.12%) than in boys(0%).The infestation rate among schoolchildren varied from 12.62%to 29.76%.The infestation rate among girls varied from 26.07%(12 years old group) to 55.89%(8 years old group).Conclusions: Pediculosis is a common public healtli problem affecting primary schoolchildren in eastern area of Bangkok and those levels are epidemic importance. 展开更多
关键词 PEDICULOSIS capitis Epidermiology SCHOOLCHILDREN EASTERN area of bangkok
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异常血红蛋白Hb J-Bangkok的分子诊断及血液学特征分析 被引量:9
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作者 胡听听 郭浩 +2 位作者 秦丹卿 杜丽 尹爱华 《临床检验杂志》 CAS 2020年第3期171-174,共4页
目的分析基因检测为异常血红蛋白Hb J-Bangkok患者的血液学特征。方法采集9例经血红蛋白电泳筛查为Hb J带患者的外周血标本进行血常规检测和血红蛋白电泳检测;采用液相芯片检测和基因测序方法检测患者的基因型。结果9例患者均检出β珠... 目的分析基因检测为异常血红蛋白Hb J-Bangkok患者的血液学特征。方法采集9例经血红蛋白电泳筛查为Hb J带患者的外周血标本进行血常规检测和血红蛋白电泳检测;采用液相芯片检测和基因测序方法检测患者的基因型。结果9例患者均检出β珠蛋白基因c.170 G>A突变(codon 56 GGC>GAC),为异常血红蛋白Hb J-Bangkok;其红细胞参数指标中血红蛋白含量(Hb)、平均红细胞体积(MCV)和平均血红蛋白含量(MCH)正常或轻度异常;5例红细胞参数完全正常;1例血红蛋白筛查Hb A2(1.9%)降低,其他红细胞参数略有降低,基因芯片检测结果为(αQSα/)杂合突变;1例Hb和MCV均降低,血清铁蛋白(FER)降低;1例Hb较低(103 g/L),其他红细胞参数正常;1例血红蛋白轻度降低(114 g/L),其他血液学指标正常,其测序结果为β珠蛋白基因c.170 G>A纯合突变(homo codon 56 GGC>GAC)。结论单纯的Hb J-Bangkok杂合子或纯合子对临床血液学影响不明显,但合并其他血液学疾病时其红细胞参数多可改变。 展开更多
关键词 HB J-bangkok 异常血红蛋白 地中海贫血 纯合突变
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An environmental approach for used oil management in Asian cities: a Bangkok's experience 被引量:1
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作者 SHING TET LEONG PREECHA LAORTANAKUL 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2003年第6期734-743,共10页
This paper addresses increasing concern about the pollution threat of used oil being illegally dumped and the impact of oil on air pollution and freshwater ecosystems in Asian countries. Used oil is a very serious was... This paper addresses increasing concern about the pollution threat of used oil being illegally dumped and the impact of oil on air pollution and freshwater ecosystems in Asian countries. Used oil is a very serious waste management problem. These results call for management action such as maximising the collection and recovery of used oil. The Thai government recognizes the need to recycle used oil and has been active in encouraging programs to accomplish this goal. Thus unless new approaches and incentives are developed, used oil generation may become an increasing serious problem to our environment. The purpose of this study is to examine the technical and economic feasibility, of recycling used oils. In addition, this paper briefly discusses the problems to be overcome and outlines potential mechanisms for providing the necessary disposal controls in order to maximize the protection to public health and environmental quality from potential hazards posed by used lube oil disposal. 展开更多
关键词 bangkok health effects oil pollution recycling used oil collection
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Managing the Chao Phraya River and Delta in Bangkok, Thailand: Flood Control, Navigation and Land Subsidence Mitigation 被引量:1
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作者 Kenneth R. Olson William Kreznor 《Open Journal of Soil Science》 2021年第4期197-215,共19页
Land subsidence as a result of the groundwater withdrawals in the Chao Phraya Delta in Thailand will be studied along with any successful remediation efforts. Most of the deltas of South East Asia are sinking for a va... Land subsidence as a result of the groundwater withdrawals in the Chao Phraya Delta in Thailand will be studied along with any successful remediation efforts. Most of the deltas of South East Asia are sinking for a variety of reasons. Thailand has national concerns related to land subsidence as a result of sea level rise, climate change, flooding, storm surges, skyscrapers, compaction, and groundwater extraction for rice paddies, shrimp ponds and the drinking water and household needs of approximately 15 million people living on the Chao Phraya Delta. The Chao Phraya River shoreline line is eroding and significant land areas and wetlands are being lost and becoming open water. Urban areas are periodically flooded and require earthen levees or floodwalls. The objective is to assess and mitigate land subsidence as a result of groundwater withdrawals for rice paddies, aquaculture, shrimp ponds, industry, drinking water and household needs of 15 million people living on Chao Phraya Delta in Bangkok. The impact of groundwater extraction and reduced sedimentation on land subsidence in the Chao Phraya Delta will be assessed and mitigation methods recommended. Lessons learned and successful remediation efforts in one Southeast Asia delta may or may not be applicable to other South East Asia deltas. There need to be mitigation methods identified to add sediment to existing Chao Phraya Delta wetlands. River water also needs to be injected deep into the underlying alluvial sediments in the delta. Navigation in the canal systems could be adversely affected by proposed massive Chao Phraya River water injections into the Chao Phraya Delta alluvial sediments underlying Bangkok. 展开更多
关键词 Ayutthaya Port of bangkok Shore Erosion Gulf of Thailand Rice SHRIMP
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Blossoms in Southeast Asia to serve thousands of enterprises——METAL AP 2018 Successfully Held in Bangkok, Thailand
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《China Foundry》 SCIE 2018年第6期476-477,共2页
Asia-Pacific Metal Industry Exhibition (METAL AP 2018)was successfully held in Bangkok International Trade and Exhibition Center (BITEC)on September 19-21,2018,attracting about 70 exhibitors of global foundry (especia... Asia-Pacific Metal Industry Exhibition (METAL AP 2018)was successfully held in Bangkok International Trade and Exhibition Center (BITEC)on September 19-21,2018,attracting about 70 exhibitors of global foundry (especially die casting),metallurgy and furnace industries,and trade visitors on automobile, electronics,communication. 展开更多
关键词 METAL AP bangkok Thailand ASIA-PACIFIC METAL Industry Exhibition BITEC
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Investigating Users’Perspectives of Coworking Space:Cases of Bangkok CBD
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作者 Sonthya Vanichvatana 《Chinese Business Review》 2018年第9期465-478,共14页
investment of this type of business is not complex.Hence,the survival of this type of business is not easily guaranteed because of not only high competitiveness but also unclear information from the user side.Entrepre... investment of this type of business is not complex.Hence,the survival of this type of business is not easily guaranteed because of not only high competitiveness but also unclear information from the user side.Entrepreneurs of coworking spaces need to understand the characteristics and perspectives of users which may differ in various regions and cultures.This research investigated the users of coworking spaces in terms of their characteristics,behaviors,and perspectives.The scope focused on coworking spaces locating on or closed to the mass train transit stations of CBD Bangkok.The research applied quantitative approach through questionnaire surveys with 300 respondents during November,2017.There are many interesting results found from the analysis and somehow differ from past studies.The majority of respondents were younger than 25 years old who were students.However,a quarter of those were“Corporate Employee”.Coffee shop was the top place to work outside own office,seconded by coworking spaces.The behaviors of the majority of the respondents included:80%visited coworking spaces at least one a week and almost half visited 3-4 times a week;they spent at least three hours per visit and about 15%spent longer than six hours.The perspectives of most respondents were used coworking spaces to increase productivity and chose a place based on location.The results call for further analysis and studies. 展开更多
关键词 bangkok CBD(Central BUSINESS District) coworking coworking space ENTREPRENEUR user perspective
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Tianjin Temple Fair in Bangkok
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《China & The World Cultural Exchange》 2019年第2期5-5,共1页
On January 29, Tianjin Culture Temple Fair, part of the 201 9 "Happy Chinese New Year" in Thailand, was held at Central? World一a very popular shopping mall in Bangkok.
关键词 TIANJIN CULTURE HELD at CENTRAL bangkok
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The Traditional Handicraft Industries of Macao Exhibition in Bangkok
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作者 Chen Boqian 《China & The World Cultural Exchange》 2018年第12期31-31,共1页
In order to support the prosperity and development of the cultural undertakings and promote international cultural exchanges in Macao,The Memorable Time--the Traditional Handicraft Industries of Macao exhibition opene... In order to support the prosperity and development of the cultural undertakings and promote international cultural exchanges in Macao,The Memorable Time--the Traditional Handicraft Industries of Macao exhibition opened in China Cultural Center in Bangkok on November 10.It was co-hosted by the Bureau of International Exchanges and Cooperation Department of Hong Kong,Macao and Taiwan Affairs ,Ministry of Culture and Tourism of the People's Republic of China,Cultural Affairs Bureau of the Macao Special Administrative Region Government and China Cultural Center in Bangkok. 展开更多
关键词 MACAO China bangkok CULTURAL BUREAU
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ZTE Shines at Bangkok ICT EXPO 2005
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《ZTE Communications》 2005年第3期69-69,共1页
关键词 EXPO ZTE Shines at bangkok ICT EXPO 2005 ICT
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ZTE Brings 3G to Bangkok International ICT EXPO 2006
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《ZTE Communications》 2006年第3期1-1,共1页
关键词 ICT EXPO ZTE Brings 3G to bangkok International ICT EXPO 2006
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CNTO Bangkok:Infinite Possibilities for Overseas Promotion of Culture and Tourism
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作者 Zheng Haohao 《China & The World Cultural Exchange》 2021年第12期15-17,共3页
The China National Tourism Office,Bangkok(CNTO Bangkok)has developed several work methods and models through its successful organization of the"Together for Beijing Winter Olympics"series in Thailand as well... The China National Tourism Office,Bangkok(CNTO Bangkok)has developed several work methods and models through its successful organization of the"Together for Beijing Winter Olympics"series in Thailand as well as many other innovative promotions. 展开更多
关键词 PROMOTION TOGETHER bangkok
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Sanya-Bangkok Direct Flight
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《China Report ASEAN》 2019年第2期9-9,共1页
A direct air route launched on February 1 connects Sanya, a resort city at the southern tip of China’s southern Hainan Province, to Bangkok, capital of Thailand.
关键词 Sanya bangkok FLIGHT
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World Judicial Experts Discuss Strategies for Eradicating Violence Against Children——Summary of Intergovernmental Experts Meeting in Bangkok
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作者 YAN JIA 《The Journal of Human Rights》 2014年第5期36-38,共3页
From February 18-21, 2014, a panel of experts, which was established by a resolution of the United Nations Economic and Social Council to draft exemplary strategies and implementation measures for eradicating violence... From February 18-21, 2014, a panel of experts, which was established by a resolution of the United Nations Economic and Social Council to draft exemplary strategies and implementation measures for eradicating violence against children in crime prevention and criminal judicature, convened in Bangkok, Thailand, for an intergovernmental experts meeting mainly to discuss the draft. After general discussion, delib- eration by the presidium and detailed negotiations, the meeting produced the report, "Exemplary Strategies and Implementation Measures for Eradicating Violence Against Children in Crime Prevention and Criminal Judicature." 展开更多
关键词 Summary of Intergovernmental Experts Meeting in bangkok World Judicial Experts Discuss Strategies for Eradicating Violence Against Children
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The Thai GoodWalk Index and the Thai Walkability Index:their application to urban regeneration exemplified by a historic riverside neighbourhood in Bangkok,Thailand
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作者 Niramon Serisakul Adisak Guntamueanglee +2 位作者 Thanaporn Ovatvoravarunyou Munchuchada Dechakaneewong Preechaya Navaraj 《Built Heritage》 CSCD 2024年第2期89-102,共14页
The urban heritage regeneration strategy through walkability is widely accepted.However,in the context of a developing country,the tools to measure walkability,which are crucial for urban planning and development,stil... The urban heritage regeneration strategy through walkability is widely accepted.However,in the context of a developing country,the tools to measure walkability,which are crucial for urban planning and development,still need to be improved.This article investigates ways to revitalise a run-down historic riverside area in Bangkok.It develops two indices,the Thai GoodWalk Index(TGWI)and the Thai Walkability Index(TWI).A hybrid of both indices is based on geospatial techniques and technology to optimise problem analysis processes,create problem-solving options,enhance spatial site selection decision capabilities,and assist urban planners in carrying out spatial scenario planning processes.It demonstrates how the GoodWalk Index has been employed to plan and prioritise urban development projects.This is exemplified by the Master Plan for the Regeneration of Kadeejeen-Klongsan,a historic riverside neighbourhood in Bangkok with limitations in density,functional mix of spaces,and access networks,especially in riverfront areas.The TGWI and TWI can be applied to the regeneration of other historic districts throughout Thailand. 展开更多
关键词 Thai GoodWalk Index Thai Walkability Index Measuring walkability Spatial scenario planning processes Historic riverside neighbourhood bangkok
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Improvements in rainfall estimation over Bangkok,Thailand by merging satellite,radar,and gauge rainfall datasets with the geostatistical method
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作者 Parichat Wetchayont Chaiwat Ekkawatpanit +1 位作者 Sunsern Rueangrit Jittawat Manduang 《Big Earth Data》 EI CSCD 2023年第2期251-275,共25页
Bangkok is located in a low land area,and floods frequently occur from rainfall,river discharge,and tides.High-accuracy rainfall data are needed to achieve high-accuracy flood predictions from hydrological models.The ... Bangkok is located in a low land area,and floods frequently occur from rainfall,river discharge,and tides.High-accuracy rainfall data are needed to achieve high-accuracy flood predictions from hydrological models.The main objective of this study is to establish a method that improves the accuracy of precipitation estimates by merging rainfall from three sources:an infrared channel from the Himawari-8 satellite,rain gauges,and ground-based radar observations.This study applied cloud classification and bias correction using rain gauges to discriminate these errors.The bias factors were interpolated using the ordinary kriging(OK)method to fill in the areas of estimated rainfall where no rain gauge was available.The results show that bias correction improved the accuracy of radar and Himawari-8 rainfall estimates before their combination.The merged algorithm was then adopted to produce hourly merged rainfall products(GSR).Compared to the initial estimated product,the GSR is significantly more accurate.The merging algorithm increases the spatial resolution and quality of rainfall estimates and is simple to use.Furthermore,these findings not only reveal the potential and limitations of the merged algorithm but also provide useful information for future retrieval algorithm enhancement. 展开更多
关键词 QPE MERGING weather radar Himawari-8 bangkok
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异常血红蛋白(Hb J-Bangkok)合并β地中海贫血的临床表型分析 被引量:19
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作者 赵颖 商璇 +3 位作者 熊符 刘彦慧 娄季武 徐湘民 《中华医学遗传学杂志》 CAS CSCD 北大核心 2013年第2期148-151,共4页
目的分析异常血红蛋白[HbJ—Bangkok(βCDS6〉GAC)]杂合子及其合并β地中海贫血(简称β地贫)突变的双重杂合子的血液学指标,分析携带该异常血红蛋白突变的表型特征及其对β地中海贫血表型的修饰作用。方法收集1个携带有HbJ—Bangko... 目的分析异常血红蛋白[HbJ—Bangkok(βCDS6〉GAC)]杂合子及其合并β地中海贫血(简称β地贫)突变的双重杂合子的血液学指标,分析携带该异常血红蛋白突变的表型特征及其对β地中海贫血表型的修饰作用。方法收集1个携带有HbJ—Bangkok/β-地贫突变的家系以及3例散发的Hb J—Bangkok携带者样本,对其进行血常规分析和血红蛋白电泳,分析并测定α和β珠蛋白基因型。结果家系中的父亲和3例散发样本均为Hb J—Bangkok杂合子,红细胞参数均正常,但血红蛋白电泳显示有Hb J异常带,无其他临床表型。先证者为HbJ—Bangkok合并B地贫IVS-Ⅱ-654突变的双重杂合子,其血液学表型与单纯β地贫杂合子类似,具有小细胞低色素贫血特征,血红蛋白电泳结果HbA2上升,并有高含量Hb J异常带。结论单纯HbJ—Bangkok杂合子无临床表型。Hb J-Bangkok合并B地贫突变不会加重其临床症状。因此携带Hb J—Bangkok突变不会对个体的临床表型产生影响。当HbJ—Bangkok突变携带者与β地贫携带者婚配时无需进行产前诊断。 展开更多
关键词 异常血红蛋白 Β地中海贫血 HB J-bangkok 临床表型
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