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Evaluation of Topical Application of Vajradanti Gel in Prevention of Gingivitis
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作者 Anjani Kumar Pathak Vibha Singh +3 位作者 Mahesh Pal Tripti Mishra Kopal Goel Vaibhav Sheel Gupta 《Open Journal of Stomatology》 2017年第2期105-112,共8页
Vajradanti means strong teeth in Hindi. The medicinal properties of Vajradanti plant are well reported in Ayurveda. Its botanical name is Barleria prionitis L. and it belongs to family Acanthaecae. The use of herbal p... Vajradanti means strong teeth in Hindi. The medicinal properties of Vajradanti plant are well reported in Ayurveda. Its botanical name is Barleria prionitis L. and it belongs to family Acanthaecae. The use of herbal products in the field of medicine has gained popularity in recent years. In India, herbal plants are used as a regular source of medicine. Plants, such as Turmeric, Ashoka and Triphala, are some common household names being widely used nowadays. One such name is Barleria prionitis L. or Vajradanti, having anti-arthritic, anti-inflammatory and anti-fertility properties. The leaves of this flower are also believed to provide relief in tooth ache. So these properties lead us to the use of this shrub in the remedy of dental diseases. Materials and Methods: The study was conducted in the Department of Periodontology, in collaboration with the Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King George’s Medical University, Lucknow, India and N.B.R.I. Lucknow. A total of 80 subjects, from age group 20 - 50 years, were selected. The study unit consisted of patients of chronic gingivitis. Simple random sampling, utilizing computer generated random numbers, was employed to assign the participants to two groups, “I” and “II”, each having 40 participants. In patients of Group-I scaling and root planing was performed, whereas in patients of Group-II, scaling and root planing was performed and subjects were advised to apply Vajradanti gel twice daily after brushing. Statistical Analysis: Data were summarized as mean ± SD. Pre and post outcome results of two groups were compared by the paired t-test. Conclusions: Based on the observations and results of our study, it can be concluded that scaling and root planing remains the gold standard for the treatment of gingival and periodontal diseases while the Vajradanti gel (Barleria prionitis L.) can be effectively used as an adjunct to mechanical plaque control in prevention of chronic gingivitis. The beneficial effect of Vajradanti can be attributed to its anti inflammatory properties. 展开更多
关键词 Vajradanti CHRONIC GINGIVITIS barleria prionitis l. Bio FIlM PlAQUE
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Gastroprotective effect of the iridoid fraction from Barleria prionitis leaves on experimentally-induced gastric ulceration 被引量:2
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作者 Sunil K.Jaiswal Mukesh K.Dubey +1 位作者 Sanjib Das Ch.V.Rao 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2014年第10期738-744,共7页
AIM: To study the gastroprotective effect and in vivo antioxidant potential of a standardized iridoid fraction from B. prionitis leaves(BPE) against different gastric ulcer models in rats. METHOD: The standardized iri... AIM: To study the gastroprotective effect and in vivo antioxidant potential of a standardized iridoid fraction from B. prionitis leaves(BPE) against different gastric ulcer models in rats. METHOD: The standardized iridoid fraction from BPE at 50, 100, and 200 mg/kg body weight was administered orally, twice daily for 5 days for prevention from aspirin, ethanol, cold-restraint stress(CRS), and pylorus ligation(PL)-induced ulcers. Estimation of the antioxidant enzyme activity was carried out in a CRS-induced ulcer model, and various gastric secretion parameters including volume of gastric juice, acid output, and pH value were estimated in the PL-induced ulcer model. RESULTS: BPE showed a dose-dependent ulcer protective effect in PL(18.67%–66.26% protection), aspirin(24.65%–63.25% protection), CRS(20.77%–59.42% protection), and EtOH(16.93%–77.04% protection)-induced ulcers. BPE treatment in PL-rats showed a decrease in acid-pepsin secretion, and enhanced mucin and mucosal glycoproteins. However, BPE reduced the ulcer index with significant decrease in LPO(P < 0.01–0.001), SOD(P < 0.01–0.001), and an increase in CAT(P < 0.01–0.001), activity in the CRS-induced model. CONCLUSION: The data shows that the iridoid fraction from BPE possesses anti-ulcerogenic and antioxidant potential. 展开更多
关键词 barleria prionitis IRIDOID HPTlC Anti-ulcer activity Antioxidant enzymes
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假杜鹃中总黄酮的含量测定 被引量:3
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作者 刘冬珠 朱全红 张宏伟 《中医药导报》 2009年第2期77-78,共2页
目的:建立假杜鹃中总黄酮含量的测定方法,并测定其含量。方法:以硝酸铝、亚硝酸钠及氢氧化钠为显色剂,利用紫外分光光度计测定假杜鹃中总黄酮的含量。结果:最佳检测波长为510nm,芦丁质量浓度在0.0151-0.30897mg/mL范围内,吸收度与质量... 目的:建立假杜鹃中总黄酮含量的测定方法,并测定其含量。方法:以硝酸铝、亚硝酸钠及氢氧化钠为显色剂,利用紫外分光光度计测定假杜鹃中总黄酮的含量。结果:最佳检测波长为510nm,芦丁质量浓度在0.0151-0.30897mg/mL范围内,吸收度与质量浓度呈良好的线性关系,回归方程为y=11.471x+0.005(r=0.9998),测定的平均回收率为RSD%=0.88%,精密度试验RSD%=0.0247%,重复性试验RSD%=2.79%,稳定性实验RSD%=0.13%。结论:利用紫外分光光度法测定假杜鹃中总黄酮的含量,简便快速且有良好的稳定性、准确性和重现性,可用于药材的质量控制。 展开更多
关键词 假杜鹃 总黄酮
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