Organization of pattern information in the pattern based software development:A POMSDP model

Foeused on the lack of proper organization for patterns in the development of pattern based software, a POMSDP model with layered tree structure for organizing patterns during the process of development was put torward. The model and its interrelated eoneepts were strictly defined and introduced by applying the theory of set, symbolie logic and pattern, which ensures the correctness, maturity and expansibility of the model. The expansibility of the model was discussed mainly. The basic realization and the application in the automatic query system were presented. Based on the existing software development methods, the POMSDP model resolves the problem of chaos in the application of patterns, strengthens the controllability of the system, and facilitates the improvement, maintenance, expansion, and especially the reengineering of the software system.

User Interface Development Based on Ontologies

The user interface is a central component of any mo de rn application program. It determines how well end users accept, learn, and effi ciently work with the application program. The user interface is very difficult to design, to implement, to modify. It takes approximately 70% of the time requ ired for designing an application program. All the existing tools for user interface design can be divided into two basic c ategories-Interface Builders and Model-based Interface development tools, whic h trace their roots from user interface management systems. Interface Builders a re the most widespread and excellent to create layouts and manipulate widgets. H owever, Interface Builders have the follow demerits. An interface designed using Interface Builders can contain hundreds of procedures. Interface Builders give us no possibility to develop different pieces of the same interface separately. They do not help us in managing user tasks and can be used only by programmers. Model-based interface development tools have attracted a high degree of interes t in last few years. The basic premise of model based technology is that the interface development can be fully supported by declarative models of all user interface characteristics such as their presen tation, dialogue, domain of application etc, and then the user interface develop ment can be centered around such models. The high potential of this technology has not been realized yet. This fact has the following reasons. The known interface models are partial representations of interfaces. They cannot be readily modified by developers, and are not publicly available to the HCI community. The central ingredient for success in model-ba sed systems is a declarative, complete, versatile interface model that can expre ss a wide variety of interface designs. Therefore tool developers have to avoid the following disadvantages of current interface models: inflexibility, system- dependence, and incompleteness. The main idea to achieve these model character istics mention above is to use ontologies. This broadened interest in ontologies is based on the fact that they provide ma chine-understandable representation of semantics for information, and a shared and common understanding of a domain that can be communicated between people and across application systems. Support in data, information, and knowledge exchang e becomes the key issue in current computer technology. At the moment we are on the brink of the second Web generation called Semantic Web or Knowledgeable Web. Given the increasing amount of information available on-line, this kind of sup port is becoming more important day by day. The main idea of the proposed approach is to replace interface models by appropr iate ontologies. Some parts of these ontologies will be available from the Inter net; the other parts will be built by developers. As a result of the Semantic We b development we will have increasing the number of ontologies formally describe d in the Internet. The terminology and content of these ontologies will be inter nationally standardized. Reusing these ontologies will bring down the cost of de velopment and improve the quality of user interface. The parts of a user interface model are-a domain ontology model, a dialog ontol ogy model, presentation ontology model, "business- logic" variable ontology mod el and correspondences between these parts. Thus, the user interface development based on ontologies is an evolution of th e model-based approach, where appropriate ontologies are used instead of models .

The Development of Gear Pump CAD/CAPP Based on Solid Works

Nowadays, many kinds of software, which have succes sf ully created the integration of CAD, CAPP and CAM, find their disadvantages in p ractical manufacturing. As a result, it is welcomed to develop small CAD/CAPP sy stems on a proper CAD platform, which aim at requirements of factories. Based on the one of the most popular three-dimensional design software SolidWorks, we successfully developed a set of gear pump CAD /CAPP software for Huaiyin Gene ral Factory of Mechanics. 1 The architecture and function of the software According to the need of the enterprises, the general structure of the software contain two subsystems, which are detailed as follows: · The gear pump CAD subsystem contains four main modules, including the optiona l design module of gear pump, module of part design, the module of entity modeli ng and the module of drawing which creates 2 D drawings of parts and assembly c orresponding 3 D modals. · The gear pump CAPP subsystem, which is a combination of creative mode and der ivate mode, also includes four modules, they are the module of access to feature s, the module of planning process route, the module of designing process sheets and the module of generating process documents. 2 The developing environment of the system Basing on Windows 98 and SolidWorks2001 platform, this system creates all functi ons by using Visual C++ 6.0 as developing tools. 3 The keys to the CAD/CAPP integration 3.1 The establishment of product information modal The information of parts is the basis of process planning. In this system, we us e feature modeling to describe the information of parts and assembly of gear pum p, and set up a fundamental basis for the whole system. The information module o f gear pump includes the information of both the assembly and the parts; the par t-describing module uses four-layer structure that is subassembly layer, part layer, feature layer and geometric layer. 3.2 The operation of the information on feature modeling After establishment of information mode of gear pump, the next key problem is ho w to transmit information of product to CAPP subsystem. In order to integrate pe rfectly, connecting CAD with CAPP directly can be a good method. In this system, all information of parts is store in the part drawing files, and the CAPP syste m can load these files to get information. The gear pumps, which are produced by Huaiyin General Factory of Mechanics, are usually belong to several similar typ es, and this means that most products possess large number of similar feature. T herefore, we can easily establish a specific feature for gear pump CAD/CAPP syst em. All parts are created by selecting these features and/or adding few special features. In the module of access to feature of CAPP subsystem, the main task is to find the features and the information will be easily got. 4 Conclusion This system successfully creates gear pump CAD/CAPP integration based on SolidWo rks. 3D CAD software provide more convenient platform for integration and will i nevitably become the mainstream of product design. By developing this system, we clearly realize the promising future of SolidWorks.

Development of a Single-Longitudinal-Mode Ho:YAG Laser Based on Corner Cube

We present a Tm-doped fiber laser pumped Fabry-Perot etalons Ho：YAG laser based on a corner cube. A maximum single-longitudinal-mode and fundamental transverse mode output power of 478 m W at the wavelength of 2091.06 nm is achieved with a pump power of 16.3 W, corresponding to an optical-to-optical efficiency of 2.9% and a slope efficiency of 7.9%. The single-longitudinal-mode and fundamental transverse mode are less sensitive to the rotating of the corner cube. The results indicate the potential impact of a single-longitudinal-mode Ho： YA G laser with corner cube geometry to improve the anti-maladjustment stability.

Optimization of fault management system in power plants based on DD-RCM and TPN

A method of optimizing the fault management system in power plants based on DD-RCM （resultchain based modeling for digital developing） and TPN （temporal Petri net） is proposed. First, the model of the fault management system was set using DD-RCM. Then, it was transformed to the temporal Petri net model by corresponding rules. Secondly, relationships among all the activities, such as choice, conflict, synchronization and concurrency, were confirmed according to the Petri net model and described employing the reengineering algorithm of incidence matrix. Thirdly, the Petri net model was reduced by combining reduction rules and conflict, synchronization relationships to optimize the fault management system in power plants. Finally, the functionality of the reduced net was proved by the temporal logic of the temporal Petri net.

Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide

The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base editor(ABE) allow generating precise and irreversible base mutations in a programmable manner and have been used in many different types of cells and organisms. However, their applications are limited by low editing efficiency at certain genomic target sites or at specific target cytosine(C) or adenine(A) residues. Using a strategy of combining optimized synergistic core components, we developed a new multiplex super-assembled ABE(sABE) in rice that showed higher base-editing efficiency than previously developed ABEs. We also designed a new type of nuclear localization signal(NLS) comprising a FLAG epitope tag with four copies of a codon-optimized NLS(F4NLS^(r2)) to generate another ABE named F4NLS-sABE. This new NLS increased editing efficiency or edited additional A at several target sites. A new multiplex super-assembled CBE(sCBE) and F4NLS^(r2) involved F4NLS-sCBE were also created using the same strategy. F4NLS-sCBE was proven to be much more efficient than sCBE in rice. These optimized base editors will serve as powerful genome-editing tools for basic research or molecular breeding in rice and will provide a reference for the development of superior editing tools for other plants or animals.

OBE理念下Seminar教学法在发展心理学课程中的应用

为适应当前社会发展对应用型心理学人才的需求,结合发展心理学课程的特点,尝试将OBE理念和Seminar教学方法相融合用于发展心理学课程的教学,旨在提升学生的职业能力。以社会需求为导向,通过“社会需求-职业能力-毕业要求”来反向设计课程目标;以学生为中心,通过教师带领小组研讨式学习完成Seminar教学法的具体教学模式,串起“课前导学-课中研讨交流-课后巩固拓展”三个环节,从而弥补传统教学的不足,提升学生的综合素质,达到更好的教学效果。

Hiatt-Neu-Cooper神经发育综合征一例

Hiatt-Neu-Cooper神经发育综合征(HINCONS)是一种与7p14上RALA的杂合突变密切相关、以智力发育障碍或全面性发育落后为突出表现的罕见神经发育遗传病,目前尚无有效治疗手段。本文报道1例HINCONS患儿,主要表现为全面性发育落后,特别是语言和运动发育落后、全身肌张力减低、身材矮小、特殊面容及先天性室间隔缺损,实验室生化检查未见明显异常,头颅MRI提示透明隔间隙、穹窿间隙增宽,家系全外显子组测序提示患儿携带RALA基因c.475(exon4)A>G(p.K159E)变异,为新发变异。现结合文献报道的12例HINCONS患者临床特征进行回顾分析,以期为HINCONS的临床诊断与遗传咨询提供参考依据。

基于前馈控制的母乳口腔护理结合发展性照顾预防早产儿喂养不耐受的效果及对生长发育、内环境的影响

目的探讨基于前馈控制的母乳口腔护理结合发展性照顾预防早产儿喂养不耐受的效果及对生长发育、内环境的影响。方法选取2020年1月至2022年1月我院收治的280例早产儿为研究对象,根据护理方法的不同将其分为对照组和观察组,各140例。对照组施以常规护理,观察组在常规护理基础上施以基于前馈控制的母乳口腔护理结合发展性照顾。比较两组的干预效果。结果观察组的开始母乳喂养时间、达全肠道营养时间、恢复正常体重时间及住院时间短于对照组,喂养不耐受发生率低于对照组,差异具有统计学意义(P<0.05)。干预后,观察组的头围、身长、体重及Peabody运动发育量表各维度评分高于对照组,差异具有统计学意义(P<0.05)。干预后,观察组的钙(Ca)水平高于对照组,碱性磷酸酶(ALP)水平低于对照组,差异具有统计学意义(P<0.05)。结论基于前馈控制的母乳口腔护理结合发展性照顾干预有助于提高早产儿喂养不耐受的预防效果,促进生长发育,改善内环境,值得推广。

新生儿重症监护室住院早产儿发育支持护理的最佳证据总结

目的整合新生儿重症监护室(neonatal intensive care units,NICUs)住院早产儿发育支持护理的最佳证据,为临床医护人员提供规范化评估和管理早产儿发育支持护理的循证依据。方法在指南网站和中英文数据库中系统检索有关早产儿发育支持护理的指南、专家共识、证据总结、系统评价和Meta分析,检索时限为2013年1月—2023年10月。结果共纳入29篇文献,包括7篇指南、3篇专家共识、3篇证据总结以及16篇系统评价。从7个方面总结了36条最佳证据。结论本研究总结了NICU住院早产儿发育支持护理的最佳证据,为医护人员提供循证支持。在临床实际应用中,应结合具体的临床情景,以规范管理早产儿的发育支持护理。

历史唯物主义发展辩证法:对邓小平发展思想哲学基础的一种阐释

列宁领导布尔什维克夺取政权之后,把“马克思主义的革命辩证法”发展为历史唯物主义发展辩证法;邓小平予以继承、完善和发展。对邓小平发展思想中的历史唯物主义发展辩证法的渊源与内涵的探讨,分析列宁把马克思主义革命辩证法发展为历史唯物主义发展辩证法的历史与理论逻辑,得出历史唯物主义发展辩证法具有两个主要维度:在贫穷落后国家建设社会主义的发展辩证法,在世界体系中推动社会主义发展的辩证法。

教学评一体化视角下微项目式学习的实践与探索

项目式学习能有效融合传统知识体系,培养学生自主研究与合作创新等核心职业素养,实现高校专业课程在理论研究、能力培养及价值引领的多元统一。针对当前培养中教、学、评三者脱节的困境,以《发展心理学》课程为例,将“研究特定领域发展的问题”作为微项目式学习的议题串联课程,探讨教学评一体化理念下微项目式学习的课程实践与应用。通过微项目式学习模式,重构课堂活动、目标与评价体系,实现三者的深度融合。经过教学实践得出,微项目式学习能有效培养学生深度研究与合作探索的职业素养,创新与优化教评机制,为高校教学改革提供新思路。

PBL联合CBL教学法提升专科医生诊疗能力的实践效果

目的探讨以问题为基础的教学法(problem-based learning,PBL)结合案例教学法(cased-based learning,CBL)对专科医生培训的作用及意义。方法对从事儿童生长发育疾病诊疗的53名专科医生进行培训,采用自身对照研究,比较2016年10月—2022年10月参加深圳市儿童医院内分泌科PBL联合CBL教学法工作坊培训前后的临床能力及学习能力。结果参加培训后,学员的自学能力[(5.96±0.39)分vs.(7.90±0.36)分]、文献检索能力[(5.25±0.92)分vs.(7.32±0.70)分]、医患沟通能力[(5.13±0.72)分vs.(7.74±0.69)分]和临床思维能力[(5.60±0.98)分vs.(7.32±0.70)分]均有所提高,差异有统计学意义(P<0.05)。结论应用PBL联合CBL教学法在加强专科医生的培训效果方面有显著优势,为提高内分泌专科医师培训质量提供了新的思路和方法。

全面性发育迟缓患儿大脑白质纤维束微结构异常的扩散峰度成像研究

目的使用扩散峰度成像(diffusion kurtosis imaging,DKI)评估全面性发育迟缓(global developmental delay,GDD)患儿大脑白质纤维束微结构的改变。材料与方法这项前瞻性研究纳入了37例GDD儿童作为试验组和32例性别、年龄相匹配的健康儿童作为对照组。对所有参与者进行了DKI序列扫描,经过后处理得到扩散张量和峰度张量参数。使用基于束的空间统计学方法(tract-based spatial statistics,TBSS)比较了这些参数在两组之间的差异,并将组间有显著差异纤维束内的参数值与GDD儿童的神经发育得分进行Spearman相关分析。结果与对照组相比,GDD组右侧皮质脊髓束和右侧丘脑前辐射的平均扩散率(mean diffusivity,MD)均显著升高(P均<0.05);双侧丘脑前辐射、双侧皮质脊髓束和右侧上纵束的径向扩散系数(radial diffusivity,RD)也显著升高(P均<0.05)。此外,GDD组的径向峰度(radial kurtosis,RK)则显著降低(P均<0.05),包括双侧丘脑前辐射、双侧皮质脊髓束、双侧下额枕束、双侧上纵束、双侧下纵束、小钳、左侧钩状束和右侧扣带回。相关性分析发现,左侧下纵束和左侧钩状束的平均RK值与适应性行为得分呈正相关(r=0.349、0.486,P均<0.05);左侧钩状束的平均RK值与精细动作得分和个人-社交行为得分均呈正相关(r=0.365、0.590,P均<0.05)。结论DKI技术能够检测到GDD儿童大脑白质纤维束微结构的异常,为探索GDD潜在病理机制提供了有用的价值。

童年中晚期攻击的发展轨迹和性别差异:基于母亲报告的分析

采用母亲报告的方法,对1618名儿童的攻击进行了4年(9岁～12岁)的追踪研究,分析了童年中晚期攻击的一般发展轨迹、亚组发展轨迹以及性别差异。结果发现:(1)总体上,童年中晚期儿童的攻击水平随年龄而下降。(2)基于亚组的准参数模型分析表明,童年中晚期母亲报告的儿童攻击呈现三条不同的发展轨迹,即无攻击轨迹、低攻击—下降轨迹以及持续高攻击轨迹,各轨迹组人数比例分别约为68.7%、26.8%、4.5%。持续高攻击轨迹组以及低攻击—下降轨迹组的儿童在童年晚期均面临一定程度的人际适应困难。(3)多项Logit模型以及卡方检验表明,男生更倾向于归属于攻击轨迹组(高或者低攻击轨迹组),而女生更倾向于归属于无攻击轨迹组;但这并不说明高攻击轨迹组中没有女生,约2%的女生属于高攻击轨迹组。

国内循证医学文献计量学分析

目的 :了解国内循证医学的发展趋势和状况。方法 :利用中国生物医学文献光盘数据库 (CBMdisc) ,用关键词和主题词检索出 1996至 2 0 0 0年国内发表的有关循证医学论文 ,应用文献计量学的方法对其进行统计分析研究。结果 :检出论文 86篇 ,文献量呈逐年增长趋势。循证医学国内研究热点为临床医学、药物学临床研究及心血管疾病等领域 ,但相当一部分为重复性的循证医学介绍 ,创新性不强 ,深入研究不够。国内刊载循证医学的核心期刊是《华西医学》、《中华医院管理杂志》、《中国中医药信息杂志》和《医学与哲学》。国内对循证医学研究的科研力量主要分布在华西医科大学、首都医科大学和天津医科大学。

人类积极发展的资源模型——积极青少年发展研究的一个重要取向和领域

积极青少年发展观(Positive Youth Development Perspective,PYD)自20世纪90年代出现以来迅速推动了发展心理学知识的创新与应用,其中发展资源框架(The Developmental Assets Framework)是研究者进行深入探讨与应用研究的一个重要模型。发展资源是指一系列能够有效促进所有青少年获得健康发展结果的相关经验、关系、技能和价值观,本文在这一概念的基础上介绍了发展资源模型的结构、构建与发展基础以及基于该模型的重要假设及实证研究,并在综述研究的基础上探讨了资源模型的未来研究方向。

旅游城市发展科普旅游产业的探讨

以我国著名旅游城市——杭州为例,通过对城市发展科普旅游产业的基本条件,以及现有科普基地的调查与分析,指出了科普旅游产业发展中存在的问题,提出了进一步促进科普旅游产业发展的一些建议。

资源型企业循环经济评价指标体系构建与实例分析

本文在分析了资源型企业发展循环经济特点的基础上,以PRS概念模型为基本原理,构建了资源型企业评价指标体系,以贵州开磷集团旗下子公司开磷息烽合成氨有限责任公司的生产数据进行实证分析,得出其循环经济发展水平,并进一步验证所构建指标体系的合理性与可行性。