开发了基于Android的铝板带冷轧远程监测系统。整体采用C/S架构模式,用LabVIEW软件开发了服务器端程序,并通过用于过程控制的对象连接与嵌入(Object Linking and Embedding for Process Control,OPC)技术从工业现场获取数据。客户端采...开发了基于Android的铝板带冷轧远程监测系统。整体采用C/S架构模式,用LabVIEW软件开发了服务器端程序,并通过用于过程控制的对象连接与嵌入(Object Linking and Embedding for Process Control,OPC)技术从工业现场获取数据。客户端采用模块化及面向对象的思想在Basic4Android+Java JDK+Android SDK开发环境中开发,具备用户认证、网络通信和随时随地数据实时获取并人性化显示的功能,测试运行稳定,实现了对铝板带冷轧生产的远程移动监控,达到了设计要求。展开更多
Background In a previously identified locus linked to hypertension on chromosome 15q, we identified three blood pressure candidate genes: insulin-like growth factor 1 receptor gene (IGF1R), myocyte specific enhancer f...Background In a previously identified locus linked to hypertension on chromosome 15q, we identified three blood pressure candidate genes: insulin-like growth factor 1 receptor gene (IGF1R), myocyte specific enhancer factor 2A gene (MEF2A), and paired basic amino acid cleaving enzyme 4 gene (PACE4). In this study, we te sted their associations with hypertension using haplotype analysis.Methods A total of 288 unrelated individuals, including 163 high diastolic blood pressure (DBP) subjects and 125 normal DBP subjects were enrolled in this case-control study. Twenty single nucleotide polymorphisms (SNPs) in the three genes were genotyped using polymerase chain reaction followed by restriction enzyme digestion. Haplotype analysis was accomplished in the following stages: (1) pair-wise linkage disequilibrium test among SNPs on the same gene was performed to explore blocks in which recombination is very unlikely to happen; (2) Estimation-Maximization algorithm was applied to estimate haplotype frequencies in each block; (3) the chi-square test was used to examine the specific haplotype difference, and a permutation test was used to examine the overall haplotype profile difference between cases and controls in each block.Results An estimated haplotype “CCCCG” frequency in the haplotype block on the PACE4 gene was significantly higher in high DBP cases than in controls (P<0.01). The overall estimated haplotype profile in this block was also significantly different between the cases and the controls (P<0 .001). This association indicates. Conclusions This study for the first time demonstrated that PAC E4 gene may play an important role in the regulation of DBP. This association indicates that variations influencing DBP resides in or near this genomic region.展开更多
文摘开发了基于Android的铝板带冷轧远程监测系统。整体采用C/S架构模式,用LabVIEW软件开发了服务器端程序,并通过用于过程控制的对象连接与嵌入(Object Linking and Embedding for Process Control,OPC)技术从工业现场获取数据。客户端采用模块化及面向对象的思想在Basic4Android+Java JDK+Android SDK开发环境中开发,具备用户认证、网络通信和随时随地数据实时获取并人性化显示的功能,测试运行稳定,实现了对铝板带冷轧生产的远程移动监控,达到了设计要求。
文摘Background In a previously identified locus linked to hypertension on chromosome 15q, we identified three blood pressure candidate genes: insulin-like growth factor 1 receptor gene (IGF1R), myocyte specific enhancer factor 2A gene (MEF2A), and paired basic amino acid cleaving enzyme 4 gene (PACE4). In this study, we te sted their associations with hypertension using haplotype analysis.Methods A total of 288 unrelated individuals, including 163 high diastolic blood pressure (DBP) subjects and 125 normal DBP subjects were enrolled in this case-control study. Twenty single nucleotide polymorphisms (SNPs) in the three genes were genotyped using polymerase chain reaction followed by restriction enzyme digestion. Haplotype analysis was accomplished in the following stages: (1) pair-wise linkage disequilibrium test among SNPs on the same gene was performed to explore blocks in which recombination is very unlikely to happen; (2) Estimation-Maximization algorithm was applied to estimate haplotype frequencies in each block; (3) the chi-square test was used to examine the specific haplotype difference, and a permutation test was used to examine the overall haplotype profile difference between cases and controls in each block.Results An estimated haplotype “CCCCG” frequency in the haplotype block on the PACE4 gene was significantly higher in high DBP cases than in controls (P<0.01). The overall estimated haplotype profile in this block was also significantly different between the cases and the controls (P<0 .001). This association indicates. Conclusions This study for the first time demonstrated that PAC E4 gene may play an important role in the regulation of DBP. This association indicates that variations influencing DBP resides in or near this genomic region.
