Behavioral inhibition in female college students with schizotypal traits: An event-related potential study

This study investigated behavioral inhibition in female college students with psychometrically defined schizotypal traits using a Go/NoGo task and event-related potentials (ERPs). The schizotypal-trait (n = 15) and normal control (n = 15) groups were selected based on scores of the Schizotypal Personality Questionnaire (SPQ). The Go/NoGo task consisted of Go (requires response) and NoGo (requires no response) conditions. In terms of response time and accuracy rate for the Go/NoGo task, the two groups did not differ significantly. In terms of ERPs, the control group showed greater N2 amplitudes in response to NoGo (NoGo-N2) than to Go stimuli (Go-N2), whereas the schizotypal-trait group showed no significant difference in NoGo-N2 and Go-N2 amplitudes. In addition, the schizotypal-trait group showed reduced NoGo-N2 amplitudes at the frontal site compared to controls, and an association between SPQ scores and NoGo-N2 amplitudes measured at the frontal site. The two groups did not differ in P3 amplitudes. Since the N2 reflects the detection of response conflict and behavioral inhibition, the present results indicate that nonclinical individuals with schizotypal traits have difficulties in detecting response conflict and behavioral inhibition.

Effects ofslip mode on microstructure evolution and compressive flow behavior of extruded dilute Mg−0.5Bi−0.5Sn−0.5Mn alloy

The influence of the slip mode on the microstructure evolution and compressive flow behavior at different strains in an extruded dilute Mg−0.5Bi−0.5Sn−0.5Mn alloy was analyzed through electron backscatter diffraction,X-ray diffraction,transmission electron microscopy,and hot compression tests.The results showed that at a low strain of 0.05,the basal,pyramidaland<c+a>slip modes were simultaneously activated.Nevertheless,at the middle stage of deformation(strain of 0.1,0.2 and 0.5),theslip mode was difficult to be activated and<c+a>slip mode became dominant.The deformation process between strains of 0.2 and 0.5 was primarily characterized by the softening effect resulting from the simultaneous occurrence of continuous dynamic recrystallization and discontinuous dynamic recrystallization.Ultimately,at strain of 0.8,a dynamic equilibrium was established,with the flow stress remaining constant due to the interplay between the dynamic softening brought about by discontinuous dynamic recrystallization and the work-hardening effect induced by the activation of the basalslip mode.

Crystal Structure and Thermal Behavior of a Novel Cocrystal Consisting of 3,3’-Dinitrimino-5,5’-Bis(1H-1,2,4-triazole),H_(2)O and(CH3)_(2)SO

A typical nitroimine bistriazole（DNABT） was synthesized with high yield（90.4%） by nitration reaction from DABT in HNO3 and NH4NO3. Furthermore, a novel cocrystal（1） consisting of DNABT, H2O and DMSO in a 1：2：2 molar ratio was analysized on the crystal structure. Cocrystal 1 crystallizes in the triclinic system, space group P1 with a = 6.3124（18）, b = 8.233（2）, c = 9.775（3） A, β = 98.326（4）°, V = 481.59（74）A^3, Z = 2, Dc = 1.55 g/cm^3, F（000） = 234, μ = 0.337 mm^-1, S = 1.078, the final R = 0.0609 and w R = 0.2743. Additionally, the crystal structure is built up by four strong and seven weak hydrogen bonds. And the hydrogen bond network contributes to the stability of DNABT molecule. Typical TGA and DSC curves indicate the cocrystal 1 includes one endothermic and one exothermic decomposition processes, and the peak temperature at each process is 164.0 and 245.0 ℃. The nonisothermal decomposition kinetics analysis was performed by means of the Kissinger and Ozawa methods. The apparent activation energy（Ea） and pre-exponential factor（A） of the two decompositions are 96.0 kJ·mol^-1, 108.1 s^-1 and 215.8 kJ·mol^-1, 1018.9 s^-1, respectively.

Bis(7)-tacrine/tacrine对大鼠DRG神经元延时整流钾通道电流的调制作用

目的研究乙酰胆碱酯酶抑制剂bis(7)-tacrine/tac-rine[bis(7)-tetrahydroaminacrine]对大鼠DRG神经元的延时整流钾通道电流的调制作用。方法在急性分离的DRG神经元标本上,采用全细胞膜片钳技术记录钾通道电流,研究bis(7)-tacrine/tacrine对DRG神经元延时整流钾通道电流的影响和作用。结果 bis(7)-tacrine对延迟整流钾通道电流IDR具有浓度依赖性的抑制作用,其半量效浓度为(IC50)(0.72±0.05)μmol.L-1,而tacrine抑制的半量效浓度(IC50)(58.3±3.7)μmol.L-1。结论两种药物对DRG延时整流钾通道电流有浓度依赖性的抑制作用,bis(7)-tacrine的抑制强度高一个数量级,有利于抑制神经元的钾通道过于激活和兴奋,预防胞内钾离子过度丢失而引起的神经元凋亡,起到神经保护的作用。

图书识别系统(BIS)的构成要素及其意义

图书识别系统的核心是按照差异化的原则,使特定的图书产品与其他图书产品产生区别,并且使读者认识到这种区别。图书识别系统由三个要素构成,即理念识别、行为识别、视觉识别。其中,理念识别是图书产品最本质的部分,是图书精神性成分的静态展示过程;行为识别是通过一定的行为方式将图书产品的精神理念进行动态化展示的过程;视觉识别则是图书的静态识别方式,是以视觉符号形式将图书的精神理念传递给社会公众的过程。

Selective CDK inhibitors:promising candidates for future clinical traumatic brain injury trials

Traumatic brain injury induces secondary injury that contributes to neuroinflammation, neuronal loss, and neurological dysfunction. One important injury mechanism is cell cycle activation which causes neuronal apoptosis and glial activation. The neuroprotective effects of both non-selective （Flavopiridol） and selective （Roscovitine and CR-8） cyclin-dependent kinase inhibitors have been shown across mukiple experimental traumatic brain injury models and species. Cyclin-depen- dent kinaseinhibitors, administered as a single systemic dose up to 24 hours after traumatic brain injury, provide strong neuroprotection-reducing neuronal cell death, neuroinflammation and neurological dysfunction. Given their effectiveness and long therapeutic window, cyclin-dependent kinase inhibitors appear to be promising candidates for clinical traumatic brain injury trials.

挤压态Mg-0.5Bi-0.5Sn-0.5Ag合金的热变形行为、组织和织构演变

本文成功制备了一种新型挤压态低合金化Mg-0.5Bi-0.5Sn-0.5Ag合金(BTQ000合金)。在变形温度为400℃、应变速率为10 s^(-1)的条件下,对BTQ000合金进行热压缩实验,研究了该合金在不同应变阶段的变形机制组织和织构演变。结果表明:BTQ000合金的流变应力曲线可分为加工硬化、动态回复、稳态流变和额外应变硬化四个阶段。合金发生了明显的回复和动态再结晶,随着应变的增大,平均晶粒粒径先增大后减小,孪晶的面积分数逐渐减小,亚晶的面积分数先增后减。当应变为0.1时,亚晶的最大面积分数为76.2%,亚晶对织构类型和强度起着主导作用,而织构强度则表现出先减后增的趋势。当应变为0.4时,大量具有弥散取向的动态再结晶晶粒减少了织构的峰值强度。由此可见,亚晶和动态再结晶是影响合金织构类型和强度的主导因素。

Potential Barrier Behavior of BaTiO3-(Bi0.5Na0.5)TiO3 Positive Temperature Coefficient of Resistivity Ceramic

High-Curie-temperature （Tc） lead-free Y-doped 90 mol%BaTiO3-1O mol%（Bi0.5Na0.5 ） TiO3 ceramic with positive temperature coefficient of resistivity （PTCR） is prepared by the conventional solid state reaction in nitrogen atmosphere. The PTCR ceramic exhibits a room-temperature resistivity （p25） of ~500Ω.cm and a high PTCR effect （maximum resistivity （ρmax）/minimum resistivity （ρmin）） of ~4.5 orders of magnitude. A capacitance- voltage approach is first employed to calculate the potential barrier （ Ф ） of the grain boundary of PTCR ceramic above Tc. It is found that the potential barrier changes from 0.17 to 0.77eV as the temperature increases from 180 to 220℃, which is very close to the predictions of the Heywang-Jonker model, suggesting that the capacitance-voltage method is valid to estimate the potential barrier of PTCR thermistor ceramics.

Influence of Bi Addition on Pure Sn Solder Joints: Interfacial Reaction, Growth Behavior and Thermal Behavior

The effects of different Bi contents on the properties of Sn solders were studied. The interfacial reaction and growth behavior of intermetallic compounds（IMCs） layer（η-Cu6 Sn5 + e-Cu3 Sn） for various soldering time and the influence of Bi addition on the thermal behavior of Sn-x Bi solder alloys were investigated. The Cu6 Sn5 IMC could be observed as long as the molten solder contacted with the Cu substrate. However, with the longer welding time such as 60 and 300 s, the Cu3 Sn IMC was formed at the interface between Cu6 Sn5 and Cu substrate. With the increase of soldering time, the thickness of total IMCs increased, meanwhile, the grain size of Cu6 Sn5 also increased. An appropriate amount of Bi element was beneficial for the growth of total IMCs,but excessive Bi（≥ 5 wt%） inhibited the growth of Cu6 Sn5 and Cu3 Sn IMC in Sn-x Bi/Cu microelectronic interconnects. Furthermore, with the Bi contents increasing（Sn-10 Bi solder in this present investigation）, some Bi particles accumulated at the interface between Cu6 Sn5 layer and the solder.

Phase Behaviors in Bi-phase Simulation of Powder Segregation in Metal Injection Molding

Powder segregation induced by mold filling is an important phenomenon that affects the final quality of metal injection molding （MIM）. The prediction of segregation in MIM requires a bi-phase flow model to describe distinctly the flows of metallic powder and polymer binder. Viscous behaviors for the flows of each phase should hence be determined. The coefficient of interaction between the flows of two phases should also be evaluated. However, only viscosity of the mixed feedstock is measurable by capillary tests. Wall sticking is supposed in the traditional model for capillary tests, while the wall slip is important to be taken into account in MIM injection. Objective of the present paper is to introduce the slip effect in bi-phase simulation, and search the suitable way to determine the viscous behaviors for each phase with the consideration of wall slip in capillary tests. Analytical and numerical methods were proposed to realize such a specific purpose. The proposed method is based on the mass conservation between the capillary flows in mono-phase model for the mixed feedstock and in bi-phase model for the flows of two phases. Examples of the bi-phase simulation in MIM were realized with the software developed by research team. The results show evident segregation, which is valuable for improving the mould designs.

In-plane Tensile Behaviors of Bi-axial Warp-Knitted Composites under Quasi-static and High Strain Rate Loading

The in-plane tensile behaviors of bi-axial warp-knitted(BWK) composites under quasi-static and high strain rates loading were experimentally analyzed in this article. The tensile tests were conducted along warp direction( 0°) and weft direction( 90°) at quasi-static rate of 0. 001 s^(-1) and high strain rates ranging from 1 450 to 2 540 s^(-1),respectively. It is found that the significant strain rate sensitivity can be observed in the stress-strain curves of BWK composites. The fracture morphologies of BWK composites demonstrate that the tensile failure modes are shear failure and fiber breakage under the quasi-static testing condition while interface failure and fibers pullout are at high strain rates.

Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of Hep G2 cells

BACKGROUND Insulin-like growth factor-1 receptor(IGF-1R)is over-expressed in hepatocellular carcinoma(HCC).However,the relationship between IGF-1R activation and HCC progression remains unidentified.AIM To investigate the effects of editing IGF-1R on the biological features of HCC cells.METHODS Immunohistochemistry analyzed the expressions of IGF-1R and P-glyco protein(P-gp)in HCC tissues and their distal non-cancerous tissues(non-Ca).IGF-1R was edited with Crispr/Cas9 system,screened specific sg RNAs,and then transfected into Hep G2 cells.CCK-8,scratch wound test detected cell proliferation,migration,invasion and transwell assays,respectively.Alterations of IGF-1R and P-gp were confirmed by Western blotting.Alterations of anti-cancer drug IC_(50)values were analyzed at the cell level.RESULTS The positive rates of IGF-1R(93.6%,χ~2=63.947)or P-gp(88.2%,χ~2=58.448)were significantly higher(P<0.001)in the HCC group than those(36.6%in IGF-1R or 26.9%in P-gp)in the non-Ca group.They were positively correlated between high IGF-1R and P-gp expression,and they were associated with hepatitis B virus infection and vascular invasion of HCC.Abnormal expressions of circulating IGF-1R and P-gp were confirmed and associated with HCC progression.Biological feature alterations of HCC cells transfected with specific sg RNA showed IGF-1R expression down-regulation,cell proliferation inhibition,cell invasion or migration potential decreasing,and enhancing susceptibility of Hep G2 cells to anti-cancer drugs.CONCLUSION Edited oncogenic IGF-1R was useful to inhibit biological behaviors of Hep G2 cells.

Electron Transport Behavior of Multiferroic Perovskite BiMnO_3 Prepared by Co-Precipitation Method

Perovskite BiMnO_3 samples are successfully synthesized by the co-precipitation method at relatively low pressure and moderate temperature.The temperature dependences of resistivity are measured and systematically investigated.It is shown that the electrical resistivity increases sharply with the decrease of temperature above 210 K and the fitted results demonstrate that the thermally activated conduction model is the dominant conduction mechanism for the electron transport behaviors in this temperature region.A dual conducting mechanism,i.e.,the variable range hopping and thermal activated conduction,is suggested to be responsible for the transport behaviors of BiMnO_3 in the region of 180-200 K.Moreover,the resistivity increases slightly with the decrease of temperature below 180 K and the transport is governed by the variable range hopping mechanism.

基于改进注意力机制与VGG-BiLSTM的暴力行为检测

为解决单一深度卷积神经网络VGG特征提取的局限性,以及单一循环神经网络RNN在记忆历史信息方面的困难,提出改进注意力机制与深度时空网络的深度学习模型VBA-net的暴力行为检测方法。首先,通过VGG的深层神经网络提取关键局部特征;其次,运用改进后的注意力机制捕捉和优化最显著的特征;最后,利用双向长短期记忆网络处理过去和未来的时序数据。仿真实验结果表明,VBA-net在规模较小的HockeyFight和Movies数据集上的准确率分别达到了97.42%和98.06%,在具有多样化内容和复杂环境数据集RWF-2000和RLVS上准确率分别达到89.00%和95.50%,因此其在复杂环境的综合鲁棒性优于同类算法,可有效提升暴力行为检测任务中的准确率。

Sn-8.8Zn-x Bi合金在烧结NdFeB上的润湿过程及界面反应行为

采用座滴法研究了在Ar-5%H_(2)气氛中Sn-8.8Zn-x Bi合金在NdFeB基体上的润湿性和润湿界面形貌。结果表明,Sn-8.8Zn-x Bi合金在NdFeB基板上润湿过程分为两个阶段:以范德华力和扩散力为驱动力的非反应性润湿阶段及由界面反应产物和反应产物的吸附作用影响的反应性润湿阶段。Sn-8.8Zn-x Bi合金中随着Bi含量提高,合金的润湿性得到改善,相同加热条件下润湿时间缩短,其中Sn-8.8Zn-7Bi在NdFeB基板表面接触角为120.11°。Sn-8.8Zn-x Bi合金在NdFeB基板上的润湿类型为反应性润湿,反应产物为ζ-FeZn_(13)相。ζ-FeZn_(13)相提高了Sn-8.8Zn-x Bi合金在NdFeB表面的黏结强度,证明Sn-8.8Zn-x Bi合金可作为NdFeB表面焊料。

Bi对A390过共晶高硅铝合金摩擦磨损特性的影响

采用自行改制的MM-200型摩擦磨损试验机研究了Bi对A390过共晶高硅铝合金摩擦磨损性能的影响规律.结果表明,由于Bi的熔点只有270℃,在摩擦过程中容易熔化渗出,并在磨损表面形成铋润滑膜而起到自润滑作用,从而降低合金的摩擦系数,改善其摩擦性能的稳定性,使合金的磨损量及摩擦表面温度降低.当Bi含量为2%-3%时,合金的减摩耐磨性能最佳,其摩擦系数为0.386,磨损量为22.5 mg.

Cu对Sn-Bi焊料压入蠕变性能及显微组织的影响

以纯Sn、纯Bi、纯Cu制得Sn-Bi和Sn-Bi-Cu合金。通过压入蠕变试验得到两种合金的蠕变曲线,总结了压入蠕变随着载荷和温度的变化规律。利用X射线衍射和扫描电镜对合金的物相组成和蠕变前后的显微组织进行分析,研究了Cu元素对Sn-Bi合金压入蠕变性能及显微组织的影响。结果表明,添加Cu元素可提高Sn-Bi合金焊料的抗蠕变性能。蠕变前,Sn-Bi合金中析出相为独立存在的颗粒状Bi,加入Cu后有块状的Cu6Sn5和发亮的少量颗粒状Bi析出;蠕变后,Sn-Bi合金中析出的Bi相变得细小并弥散分布于基体中,添加Cu后的合金中由于发生再结晶,块状析出相边缘变得光滑且有小块状Cu6Sn5,但含Bi的析出相几乎没有了。

Bi-20.5Te合金熔体结构转变及其对凝固的影响

通过对Bi-20.5Te合金熔体电阻率随温度变化的研究,发现合金熔体在642℃时存在着液-液结构转变。分析Bi-Te合金熔体在不同成分和不同温度的原子结合规律,认为这种结构转变是由于熔体中的原子团簇变化引起的。将Bi-20·5Te合金分别在熔体结构转变前温度(600℃)、结构转变后温度(700℃)的范围内熔炼、保温,测定相应的凝固曲线,并观察凝固组织。结果表明,相对于在结构转变前保温处理的熔体,将合金在700℃保温处理后,凝固时所需过冷度增大,释放凝固潜热更加剧烈,并且凝固组织显著细化。产生这种现象的原因是由于熔体结构内的Bi-Bi同类原子团簇,以及具有共价结合的Bi-Te原子团簇在高温下被打破,熔体趋向均匀,对凝固过程中的原子扩散造成影响,进而影响合金的凝固行为及组织。

基于双流CNN与Bi-LSTM的施工人员不安全行为轻量级识别模型

由于PC端的施工人员不安全行为识别模型计算复杂度高、模型体积大,不适合在边缘设备上运行,提出了一种基于双流CNN与Bi-LSTM的轻量级识别模型。模型主要包含双流CNN特征提取、特征融合和行为分类3个模块,在双流CNN特征提取模块中使用高效的轻量化网络ShuffleNetV2代替传统CNN以提升计算效率,同时添加卷积注意力模块获取关键特征以提高行为识别准确率;在特征融合模块中引入Bi-LSTM网络获取视频前后的关联信息,实现双流特征融合;在行为分类模块中利用注意力机制实现自适应分配权重,从而进一步提升施工人员不安全行为识别的准确率。最后,采用UCF-101数据集和自建数据集进行模型训练和验证,该模型的累加乘积操作次数为7.73 G,参数量为5.38 M,均优于传统的双流CNN方法;此外,模型在2个数据集上的识别准确率分别为94.3%和94.8%,均优于双流CNN-MobileNetV3等其他轻量级模型。实验结果表明所提模型相对于传统双流CNN具有更低的计算复杂度、更小的模型参数量以及更高的识别准确率,适合在资源受限的边缘设备上部署与运行。

Pr(III)离子在LiCl-KCl熔体中Bi膜W电极上的电化学行为（英文）

采用循环伏安、方波伏安、计时电位和开路计时电位等电化学方法研究了Pr(III)离子在Li Cl-KCl-Bi Cl_3熔体中W电极上的电化学行为。循环伏安和方波伏安的研究表明,Pr在预先沉积的Bi膜电极上发生欠电位沉积是由于生成了Pr-Bi金属间化合物,导致Pr(III)在Bi膜电极上的还原电位比在W电极上还原电位更正。从开路计时电位曲线可以观察到两相共存的Pr-Bi金属间化合物的两个平台。利用开路计时电位计算了723-873 K温度范围内Pr在Pr-Bi合金中的活度和偏摩尔Gibbs自由能以及Pr-Bi金属间化合物的生成Gibbs自由能。通过恒电位电解,在液态Bi电极上得到了Pr-Bi合金,并采用X射线衍射(XRD)和扫描电子显微镜(SEM)附带能量散射谱(EDS)对样品进行了表征,结果表明所得到的Pr-Bi金属间化合物为Pr Bi_2和Pr Bi。