Background： We summarized the Polyporusus Bellatus （PPS） efficacy of immunomodulation, liver protection and anti-tumor, then provide scientific basis for further research and clinical application. This diss...Background： We summarized the Polyporusus Bellatus （PPS） efficacy of immunomodulation, liver protection and anti-tumor, then provide scientific basis for further research and clinical application. This dissertation first overview relevant literatures of PPS recent years and describe comprehensively the research progress of the immunoregulation, liver protection and anti-tumor effects and mechanism of PPS. The review shows that the PPS play anti-tumor effects through antioxidation, scavenging free radicals, inhibiting tumor cell proliferation, inducing apoptosis, affecting tumor gene expressions and enhancing immune functions. PPS can exert immunoregulatory, hepatoprotective and anti-tumor effects through multiple pathways and multiple targets, which provides a good application prospect in clinic.展开更多
基金The study was funded by the National Natural Science Foundation of Hebei （No.H2018201179）. Hebei University of Science and Technology （No. QN2016077）. Health and Family Planning Commission of Hebei （No. 20160388）.
文摘Background： We summarized the Polyporusus Bellatus （PPS） efficacy of immunomodulation, liver protection and anti-tumor, then provide scientific basis for further research and clinical application. This dissertation first overview relevant literatures of PPS recent years and describe comprehensively the research progress of the immunoregulation, liver protection and anti-tumor effects and mechanism of PPS. The review shows that the PPS play anti-tumor effects through antioxidation, scavenging free radicals, inhibiting tumor cell proliferation, inducing apoptosis, affecting tumor gene expressions and enhancing immune functions. PPS can exert immunoregulatory, hepatoprotective and anti-tumor effects through multiple pathways and multiple targets, which provides a good application prospect in clinic.
