期刊文献+
共找到371篇文章
< 1 2 19 >
每页显示 20 50 100
Efficacy of Bladder Neck Incision (BNI) Versus Transurethral Resection of Prostate (TURP) in Management of Benign Prostatic Hyperplasia (BPH) Causing Obstruction: A Randomised Controlled Study 被引量:1
1
作者 Hussein H. S. Saddam Jain Sudhir Kumar Singh Chandra Bhushan 《Open Journal of Urology》 2019年第8期119-129,共11页
Objective: To compare the efficacy of bladder neck incision (BNI) with transurethral resection of prostate (TURP) in the treatment of patients with urinary obstruction caused by benign prostatic hyperplasia (BPH) on t... Objective: To compare the efficacy of bladder neck incision (BNI) with transurethral resection of prostate (TURP) in the treatment of patients with urinary obstruction caused by benign prostatic hyperplasia (BPH) on the basis of short term follow up of 4 months. Patient and Methods: The study was conducted in Department of General Surgery in Maulana Azad Medical College, New Delhi. 60 men with proven clinical diagnosis of BPH of size 30 grams and less presenting with symptoms of bladder outlet obstruction (BOO) were randomised prospectively to undergo either of the two operative modalities. Preoperatively size of the prostate, symptom scoring (IPSS), peak flow rate (Qmax) were assessed. Postoperatively and during 4 months follow up the following data were collected—operative time, catheterisation period, hospital stay, blood loss, Qmax and IPSS. Results: Preoperative parameters in both the groups showed no statistically significant differences with respect to prostate size, Qmax and IPSS Scoring. At 4 months follow up Qmax increased from (6.35 ± 4.49) to (16.41 ± 2.28) in TURP group and (4.51 ± 3.57) to (15.95 ± 2.58) in BNI group. IPSS decreased from 18.70 to 5.7 in TURP group and 18.90 to 6.00 in BNI group. All differences were statistically significant. There was a statistically significant difference in operative time, blood loss, hospital stay, catheterisation timing favouring BNI. Conclusion: TURP and BNI are equally effective in providing symptomatic improvement. BNI has an upper hand in reference to operative time, hospital stay, duration of catheterisation and blood loss. 展开更多
关键词 benign Prostatic Hyperplasia (bph) BLADDER Neck INCISION (BNI) BLADDER Outlet OBSTRUCTION (BOO) Peak Urinary Flow Rate (Qmax) International Prostate Scoring System (IPSS)
下载PDF
组织学改变在BPH并发急性尿潴留患者中的作用分析 被引量:11
2
作者 包卿兵 何国华 +2 位作者 刘光耀 张长庚 扬程 《中华男科学杂志》 CAS CSCD 2013年第9期811-814,共4页
目的:探讨前列腺梗死、前列腺组织学炎症、前列腺增生类型在良性前列腺增生(BPH)并发急性尿潴留(AUR)中的关系。方法:回顾性分析我院初诊BPH合并AUR与无AUR患者共102例,其中AUR组49例,无AUR组53例。比较两组之间前列腺梗死、前列腺组织... 目的:探讨前列腺梗死、前列腺组织学炎症、前列腺增生类型在良性前列腺增生(BPH)并发急性尿潴留(AUR)中的关系。方法:回顾性分析我院初诊BPH合并AUR与无AUR患者共102例,其中AUR组49例,无AUR组53例。比较两组之间前列腺梗死、前列腺组织学炎症、前列腺增生类型发生率。同时比较两组间年龄、国际前列腺症状评分(IPSS)、前列腺特异性抗原(PSA)、前列腺总体积(PV)。结果:AUR组血PSA较无AUR组明显升高[(8.2±4.6)μg/L vs(4.3±5.5)μg/L,P<0.05),两组患者年龄、IPSS、PV比较差异无统计学意义(P均>0.05)。前列腺增生类型与AUR无相关性(P>0.05),前列腺梗死和前列腺组织学炎症可增加BPH患者AUR发生机率,存在前列腺梗死的BPH患者发生AUR的概率是无前列腺梗死者的5.620倍(P<0.05),存在前列腺组织学炎症的BPH患者发生AUR的概率是无炎症者的2.362倍(P<0.05)。结论:前列腺梗死和前列腺组织学炎症可能是BPH患者发生AUR的危险因素。 展开更多
关键词 良性前列腺增生 急性尿潴留 前列腺梗死 前列腺炎 前列腺增生类型
下载PDF
PKRP与TUVP治疗良性前列腺增生症(BPH)的对比研究 被引量:6
3
作者 殷晓蒙 姜心 +2 位作者 周东言 沈进 杨波 《中国现代医生》 2014年第17期42-44,共3页
目的对比分析经尿道等离子电切术(PKRP)与传统电切术(TUVP)治疗良性前列腺增生症(BPH)的疗效。方法 80例行手术治疗的BPH患者中PKRP治疗的40例患者设立为观察组,另外选择同期行TUVP治疗的40例患者设立为对照组,比较两组患者手术时间及... 目的对比分析经尿道等离子电切术(PKRP)与传统电切术(TUVP)治疗良性前列腺增生症(BPH)的疗效。方法 80例行手术治疗的BPH患者中PKRP治疗的40例患者设立为观察组,另外选择同期行TUVP治疗的40例患者设立为对照组,比较两组患者手术时间及术中出血量、住院时间,两组患者术前术后IPSS、最大尿流率(Qmax)的变化以及两组患者术后并发症发生率。结果观察组的手术时间、住院时间分别与对照组比较,差异无统计学意义(P>0.05),观察组的术中出血量明显少于对照组(P<0.01)。术后观察组Qmax与对照组比较明显升高,观察组的IPSS术后较对照组明显降低,组间比较差异有统计学意义(P<0.05),观察组术后无一例发生电切综合症,其并发症发生率达5%(2/40),对照组术后并发症发生率达25%(10/40),两组并发症发生率比较,差异有统计学意义(P<0.05)。结论经尿道等离子电切术(PKRP)较传统电切术(TUVP)治疗良性前列腺增生症出血少、并发症少、术后能明显改善患者的临床症状,值得推广和应用。 展开更多
关键词 经尿道等离子电切术 传统电切术 良性前列腺增生症
下载PDF
经尿道前列腺等离子双极电切术对BPH患者术后性功能及血清PSA、PGI2水平变化的影响 被引量:14
4
作者 唐亚雄 吕天兵 +2 位作者 傅承忠 邓颖 陈雪芹 《中国性科学》 2018年第8期21-25,共5页
目的:探讨经尿道前列腺等离子双极电切术对良性前列腺增生(BPH)患者术后性功能及血清前列腺特异性抗原(PSA)、前列环素(PGI2)水平变化的影响。方法:选取内江市第一人民医院89例BPH患者,依据手术术式不同分组,对照组44例给予气化电切术治... 目的:探讨经尿道前列腺等离子双极电切术对良性前列腺增生(BPH)患者术后性功能及血清前列腺特异性抗原(PSA)、前列环素(PGI2)水平变化的影响。方法:选取内江市第一人民医院89例BPH患者,依据手术术式不同分组,对照组44例给予气化电切术治疗,观察组45例给予经尿道前列腺等离子双极电切术治疗,观察比较两组手术情况[尿管留置时间、术中出血量、术后视觉模拟评分(VAS)]及手术前后国际前列腺症状(IPSS)评分、性功能各指标[国际勃起功能指数(IIEF-5)评分、早泄患者性功能-5(CIPE-5)评分]及血清PSA、PGI2水平变化情况,并统计两组并发症发生情况。结果:与对照组相比,观察组尿管留置时间短、术中出血量少、术后VAS评分及术后IPSS评分均较对照组低,差异具有统计学意义(P <0. 05);观察组术后IIEF-5及CIPE-5评分均高于对照组,差异具有统计学意义(P <0. 05);观察组术后血清PSA水平低于对照组,血清PGI2水平高于对照组,差异具有统计学意义(P <0. 05);观察组并发症发生率为4. 44%(2/45),低于对照组20. 45%(9/44),差异具有统计学意义(P <0. 05)。结论:采用经尿道前列腺等离子双极电切术治疗可改善BPH患者术后性功能及血清PSA、PGI2水平,效果显著,并发症发生率低。 展开更多
关键词 良性前列腺增生 经尿道前列腺等离子双极电切术 性功能 血清前列腺特异性抗原 前列环素
下载PDF
检测尿NAG活性对判断BPH患者早期肾功能损害的意义 被引量:4
5
作者 管同郁 承征宇 +5 位作者 戚景光 杨宁 曹敬毅 梁杰 杨洪鹏 佟大全 《现代泌尿外科杂志》 CAS 2008年第2期94-96,共3页
目的探讨测定尿N-乙酰-β-D氨基葡萄糖苷酶(NAG)活性在判断良性前列腺增生症(BPH)患者早期肾功能损害方面的应用价值。方法检测65例BPH患者的尿NAG活性及血β2微球蛋白(β2-MG)、尿素氮(BUN)、肌肝(Cr)及最大尿流率(Qmax),并与80例年龄... 目的探讨测定尿N-乙酰-β-D氨基葡萄糖苷酶(NAG)活性在判断良性前列腺增生症(BPH)患者早期肾功能损害方面的应用价值。方法检测65例BPH患者的尿NAG活性及血β2微球蛋白(β2-MG)、尿素氮(BUN)、肌肝(Cr)及最大尿流率(Qmax),并与80例年龄匹配的正常人群进行比较分析。同时对BPH患者手术前与术后1个月和3个月的NAG活性进行比较。结果BPH患者尿NAG活性明显高于正常对照组(P<0.01),尿NAG活性与BPH患者最大尿流率呈显著正相关(P<0.01)。术后3个月尿NAG活性下降明显,与术前相比有显著性差异(P<0.01)。结论BPH患者最大尿流率较低时肾功能可能已有部分损伤,尿NAG活性水平可作为判断BPH患者早期肾功能损伤的监测指标以及手术指征之一。 展开更多
关键词 良性前列腺增生症 尿N-乙酰-Β-D氨基葡萄糖苷酶 尿流率 肾功能
下载PDF
HoLEP、TUPKEP及TURP术治疗原发性高血压合并BPH的疗效分析及对炎性因子和血清PSA水平的影响 被引量:11
6
作者 李鑫 王文生 +2 位作者 李保国 周錞 卢晓东 《中国医学装备》 2020年第1期96-100,共5页
目的:研究钬激光前列腺剜除术(HoLEP)、经尿道等离子前列腺剜除术(TUPKEP)及经尿道前列腺电切术(TURP)治疗原发性高血压合并良性前列腺增生(BPH)的疗效分析及对炎性因子和血清PSA水平的影响。方法:选取医院收治的240例前列腺增生老年患... 目的:研究钬激光前列腺剜除术(HoLEP)、经尿道等离子前列腺剜除术(TUPKEP)及经尿道前列腺电切术(TURP)治疗原发性高血压合并良性前列腺增生(BPH)的疗效分析及对炎性因子和血清PSA水平的影响。方法:选取医院收治的240例前列腺增生老年患者,将HoLEP治疗患者纳入HoLEP组(87例),TURP手术患者纳入TURP组(102例),TUPKEP手术患者纳入TUPKEP组(51例),分析三组患者的手术指标、排尿情况、生存质量、炎性因子、血清PSA和并发症之间的差异。结果:三组患者手术期间出血量、麻醉时间、输液量以及并发症等相关指标之间的差异无统计学意义;术后3个月,三组患者的IPSS评分、Qmax、RUV以及QOL比较,差异有统计学意义(F=11.225,F=62.043,F=3.360,F=62.043;P<0.05)。治疗后三组患者的炎性因子肿瘤坏死因子α(TNF-α)、IL-6、IL-8及血清PSA比较,差异有统计学意义(F=17.253,F=21.323,F=16.326,F=41.172;P<0.05)。结论:通过采取HoLEP治疗,排尿功能显著改善,患者的炎性反应以及血清PSA水平显著降低,安全性较好,患者的生命质量显著提升。 展开更多
关键词 前列腺增生(bph) 钬激光前列腺剜除术(HoLEP) 经尿道等离子前列腺剜除术(TUPKEP) 经尿道前列腺电切术(TURP) 血清前列腺特异性抗原(PSA) 生命质量 高血压
下载PDF
盐酸坦索罗辛单药治疗BPH 100例临床疗效观察 被引量:3
7
作者 罗杰鑫 王卫峰 赖俊彦 《中国实用医药》 2010年第19期29-30,共2页
目的观察坦索罗辛单药治疗BPH(良性前列腺增生症)导致的LUTS(下尿路症状)的临床疗效。方法门诊选择100例BPH患者,随机分成2组,试验组50例,服用盐酸坦索罗辛0.2mg,1次/d;对照组50例,同时服用非那雄胺5.0mg,1次/d,盐酸坦索罗辛0.2mg,1次/d... 目的观察坦索罗辛单药治疗BPH(良性前列腺增生症)导致的LUTS(下尿路症状)的临床疗效。方法门诊选择100例BPH患者,随机分成2组,试验组50例,服用盐酸坦索罗辛0.2mg,1次/d;对照组50例,同时服用非那雄胺5.0mg,1次/d,盐酸坦索罗辛0.2mg,1次/d,观察药物治疗效果,主要是下尿路症状的改善。结果 1个月内下尿路症状的有效改善为试验组49例(98%),对照组48例(96%),两组差异无统计学意义(P>0.05)。两组患者IPSS均≤13分,QOL为(3±1)分,Qmax均≤18ml/s,残余尿量测定均≤40ml,服药前后比较并有统计学意义(P≤0.05)。结论盐酸坦索罗辛单药治疗BPH导致的LUTS的临床疗效满意。 展开更多
关键词 良性前列腺增生症 下尿路症状 盐酸坦索罗辛
下载PDF
TURP联合膀胱造瘘peel-away大通道弹道碎石治疗BPH并发多发膀胱大结石 被引量:1
8
作者 林伟强 张永海 徐庆春 《河北医学》 CAS 2008年第12期1415-1416,共2页
目的:探讨一期腔内治疗BPH并发膀胱结石的有效、快捷治疗方法。方法:采用TURP联合肾镜下气压弹道碎石、清石术治疗BPH并发膀胱结石30例。结果:30例均一次手术成功,元输血、TufuP综合征及严重感染等并发症发生。术后复查KUB、膀胱内... 目的:探讨一期腔内治疗BPH并发膀胱结石的有效、快捷治疗方法。方法:采用TURP联合肾镜下气压弹道碎石、清石术治疗BPH并发膀胱结石30例。结果:30例均一次手术成功,元输血、TufuP综合征及严重感染等并发症发生。术后复查KUB、膀胱内均未见残石,清石率迭100%。住院7—9d,最大尿流率较术前明显改善。结论:TURP联合膀胱造瘘peel—away大通道肾镜下气压弹道碎石、清石术治疗BPH并发膀胱结石,创伤小、手术时间短、恢复快、安全高效,是治疗BPH并发膀胱结石的理想方法。 展开更多
关键词 前列腺增生症 膀胱结石 经尿道前列腺电切术 碎石术
下载PDF
血清TPSA、FPSA和F/TPSA检测在BPH与PCa诊断中的意义 被引量:1
9
作者 林梅双 陆予云 《医学理论与实践》 2006年第9期1013-1015,共3页
目的:探讨血清总前列腺特异性抗原(TPSA)和游离前列腺特异性抗原(FPSA)与F/TPSA比值在诊断和鉴别诊断前列腺增生(BPH)与前列腺癌(PCa)中的作用及其疗效和愈后观察。方法:采用化学发光法测定26例BPH和29例PCa患者及86例其它疾病患者血清... 目的:探讨血清总前列腺特异性抗原(TPSA)和游离前列腺特异性抗原(FPSA)与F/TPSA比值在诊断和鉴别诊断前列腺增生(BPH)与前列腺癌(PCa)中的作用及其疗效和愈后观察。方法:采用化学发光法测定26例BPH和29例PCa患者及86例其它疾病患者血清的TPSA和FPSA水平并计算F/TPSA比值。结果:非PCa病人血清的TPSA和FPSA水平与年龄有显著相关性(P<0.01),而F/TPSA与年龄无明显相关(P>0.05);随着年龄增加,PCa的发病率也增加(P<0.025);3组中PCa组的TPSA与FPSA水平明显高于其它两组(P<0.001),F/TPSA则低于其它两组(P<0.002)。结论:联合检测TPSA、FPSA和F/TPSA可明显提高BPH与PCa诊断的准确性,有助于肿瘤疾病筛选,对PCa疗效和预后观察有一定的意义。 展开更多
关键词 前列腺特异性抗原(PSA) 前列腺增生(bph) 前列腺癌(PCa) 游离PSA与总PSA的比值(F/TPSA)
下载PDF
BPH-1通过分泌PGE2上调前列腺间质细胞ERRα的表达 被引量:2
10
作者 苗琳 石建党 +4 位作者 周颖 杜小玲 吴荃 王克明 张琚 《中国生物化学与分子生物学报》 CAS CSCD 北大核心 2008年第8期742-747,共6页
雌激素受体相关受体α(estrogen receptor-related receptorα,ERRα)是一类可以直接或间接参与雌激素应答反应的孤儿核受体,它与雌激素受体(estrogen receptor,ER)在结构上有很强的同源性.雌激素效应在良性前列腺增生(benign prostatic... 雌激素受体相关受体α(estrogen receptor-related receptorα,ERRα)是一类可以直接或间接参与雌激素应答反应的孤儿核受体,它与雌激素受体(estrogen receptor,ER)在结构上有很强的同源性.雌激素效应在良性前列腺增生(benign prostatic hyperplasis,BPH)的发生和发展中起着重要的作用.通常,孤儿核受体的转录活性多受一些非经典激素如维生素A衍生物、前列腺素类、固醇的调控.本文研究前列腺上皮细胞分泌的活性因子对间质细胞ERRα表达调控的分子机制.收集前列腺增生上皮细胞系BPH-1和前列腺癌上皮细胞系DU-145的条件培养液(condition medium,CM)培养间质细胞,采用实时定量RT-PCR和Western印迹法检测前列腺间质细胞(prostatic stromal cells,PrSC)中ERRα的表达,筛选CM中影响ERRα表达的活性因子.研究结果显示,BPH-1的CM可以上调ERRα的表达,而DU-145的CM对ERRα的表达没有影响;BPH-1中合成前列腺素E2(prostaglandin E2,PGE2)的限速酶———环氧合酶2(cyclooxygenase-2,COX-2)的mRNA表达水平和PGE2的分泌水平明显高于DU-145中COX-2表达水平和PGE2分泌水平;用经添加COX-2抑制剂NS-398的培养液处理BPH-1,其CM中PGE2的浓度明显下降,并失去了对ERRα表达的上调作用;添加PGE2可上调间质细胞中ERRα的表达.结果表明,BPH-1通过分泌PGE2促进间质细胞ERRα的表达,提示:在良性前列腺增生的发生和发展中,上皮细胞的旁分泌作用可促进间质细胞由ERRα介导的雌激素效应. 展开更多
关键词 雌激素受体相关受体α(ERRα) 良性前列腺增生 上皮-间质相互作用 前列腺素E2
下载PDF
两种微创取石方案对膀胱多发结石合并BPH老年患者围手术期临床指标及安全性的影响 被引量:11
11
作者 马有才 胡森 +3 位作者 王继贤 童占表 张栋邦 刘炜 《中国性科学》 2019年第10期13-15,共3页
目的研究两种微创取石方案对膀胱多发结石合并BPH老年患者围手术期临床指标及安全性的影响。方法选取2016年1月至2017年12月在青海红十字医院治疗的140例膀胱多发结石合并BPH老年患者作为研究对象。用随机数表法分为对照组和观察组,每组... 目的研究两种微创取石方案对膀胱多发结石合并BPH老年患者围手术期临床指标及安全性的影响。方法选取2016年1月至2017年12月在青海红十字医院治疗的140例膀胱多发结石合并BPH老年患者作为研究对象。用随机数表法分为对照组和观察组,每组各70例,对照组给予TUVP联合气压弹道碎石治疗,观察组给予TUVP联合钬激光碎石术治疗。比较两组患者的围手术期临床指标、临床疗效和并发症情况等。结果观察组取石时间、手术时间、术中出血量和膀胱冲洗时间少于对照组,差异具有统计学意义(P<0.05),两组患者的导尿管置管时间和住院时间相近,差异无统计学意(P>0.05)。观察组IPSS评分、QOL评分和RUV低于对照组,Qmax高于对照组,差异具有统计学意(P<0.05)。两组患者的并发症发生率和结石排尽率相近,差异无统计学意(P>0.05)。结论 TUVP联合钬激光碎石术治疗膀胱多发结石合并BPH老年患者的效果显著,和TUVP联合气压弹道碎石术相比,能够明显改善患者的围手术期临床指标和术后疗效,两者安全性均较好,值得在临床推广应用。 展开更多
关键词 经尿道前列腺汽化电切术 钬激光碎石术 气压弹道碎石术 膀胱结石 良性前列腺增生
下载PDF
Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials 被引量:7
12
作者 Chun Ho Ma Wai Ling Lin +5 位作者 Sing Leung Lui Xun-Yuan Cai Vivian Taam Wong Kun-Yuan Cai Eric Zie Zhang-Jin Zhang 《Asian Journal of Andrology》 SCIE CAS CSCD 2013年第4期471-482,I0007,共13页
Chinese herbal medicine is commonly used as a treatment for benign prostatic hyperplasia (BPH), but its efficacy and safety remain to be examined. To compare the efficacy and adverse events of Chinese herbal medicin... Chinese herbal medicine is commonly used as a treatment for benign prostatic hyperplasia (BPH), but its efficacy and safety remain to be examined. To compare the efficacy and adverse events of Chinese herbal medicine alone or used adjuvantly with Western medications for BPH. Two independent reviewers searched the major electronic databases for randomized controlled trials comparing Chinese herbal medicine, either in single or adjuvant use with Western medication, with placebo or Western medication. Relevant journals and grey literature were also hand-searched. The outcome measures included changes in urological symptoms, urodynamic measures, prostate volume and adverse events. The frequency of commonly used herbs was also identified. Out of 13 922 identified citations of publications, 31 studies were included. Eleven studies with a Jadad score i〉 3 were selected for meta-analysis. Chinese herbal medicine was superior to Western medication in improving quality of life and reducing prostate volume. The frequency of adverse events in Chinese herbal medicine was similar to that of placebo and less than that of Western medication. The evidence is too weak to support the efficacy of Chinese herbal medicine for BPH due to the poor methodological quality and small number of trials included. The commonly used herbs identified here should provide insights for future clinical practice and research. Larger randomized controlled trials of better quality are needed to truly evaluate the efficacy of Chinese herbal medicine. 展开更多
关键词 benign prostatic hyperplasia bph META-ANALYSIS REVIEW traditional Chinese medicine
下载PDF
Photoselective green-light laser vaporisation vs. TURP for BPH. meta-analysis 被引量:6
13
作者 Hui Ding Wan Du +3 位作者 Ze-Ping Lu Zhen-Xing Zhai Han-Zhang Wang Zhi-Ping Wang 《Asian Journal of Andrology》 SCIE CAS CSCD 2012年第5期720-725,共6页
This study sought to evaluate the efficacy and safety of photoselective vaporisation (PVP) vs. transurethral resection of the prostate (TURP) for patients with benign prostatic hyperplasia (BPH). Eligible studie... This study sought to evaluate the efficacy and safety of photoselective vaporisation (PVP) vs. transurethral resection of the prostate (TURP) for patients with benign prostatic hyperplasia (BPH). Eligible studies were identified from electronic databases (Cochrane Library, PubMed and EMBASE). The database search, quality assessment and data extraction were performed independently by two reviewers. Efficacy (primary outcomes: maximum urinary flow rate (Qmax), international prostate symptom score (IPSS), postvoid residual urine (PVR) and quality of life (QoL); secondary outcomes: operative time, hospital time and catheter removal time) and safety (complications, such as transfusion and capsular perforation) were explored by using Review Manager 5.0. Six randomized controlled trials (RCTs) and five case-controlled studies of 1398 patients met the inclusion criteria. A meta-analysis of the extractable data showed that there were no differences in I PSS, Qmax, QoL or PVR between PVP and TU RP (mean difference (MD): prostate sizes 〈 70 ml, Qmax at 24 months, MD=0.01, P=0.97; IPSS at 12 months, MD=0.18, P=0.64; QoL at 12 months, MD=-0.00, P=0.96; PVR at 12 months, MD=0.52, P=0.43; prostate sizes 〉70 ml, Qmax at 6 months, MD=-3.46, P=0.33; IPSS at 6 months, MD=3.11, P=0o36; PVR at 6 months, MD=25.50,P=-0.39). PVP was associated with a shorter hospital time and catheter removal time than TURP, whereas PVP resulted in a longer operative time than TURP. For prostate sizes 〈70 ml, there were fewer transfusions, capsular perforations, incidences of TUR syndrome and clot retentions following PVP compared with TURP. These results indicate that PVP is as effective and safe as TURP for BPH at the mid-term patient follow-up, in particular for prostate sizes 〈70 ml. Due to the different energy settings available for green-light laser sources and the higher efficiency and performance of higher-quality lasers, large-sample, long-term RCTs are required to verify whether different energy settings affect outcomes. 展开更多
关键词 benign prostatic hyperplasia bph META-ANALYSIS photoselective vaporisation transurethral resection of the prostate(TURP)
下载PDF
α受体阻断剂治疗BPH研究进展
14
作者 杨智慧 任雷鸣 +2 位作者 杨小平 傅绍萱 李蕴山 《中国药理学通报》 CAS CSCD 北大核心 1998年第S1期76-79,共4页
α受体介导的前列腺尿道平滑肌张力增加是BPH相关性尿道梗阻的动力学因素,α_1受体阻断剂是目前BPH内科治疗的首选药。寻求对泌尿道有高选择性α-(1A)受体阻断剂是今后药物研制的发展方向。
关键词 良性前列腺增生症 药物治疗 Α受体阻断剂 尿道选择性
下载PDF
Urine Flow Acceleration Is Superior to Qmax in Diagnosing BOO in Patients with BPH 被引量:3
15
作者 文建国 崔林刚 +5 位作者 李一冬 尚小平 朱文 张瑞莉 孟庆军 张胜军 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2013年第4期563-566,共4页
Summary: We performed a retrospective, case-control study to evaluate whether the urine flow acceleration (UFA, mL/s2) is superior to maximum uroflow (Qmax, mL/s) in diagnosing bladder outlet obstruction (BOO) ... Summary: We performed a retrospective, case-control study to evaluate whether the urine flow acceleration (UFA, mL/s2) is superior to maximum uroflow (Qmax, mL/s) in diagnosing bladder outlet obstruction (BOO) in patients with benign prostatic hyperplasia (BPH). In this study, a total of 50 men with BPH (age: 58±12.5 years) and 50 controls (age: 59±13.0 years) were included. A pressure-flow study was used to determine the presence of BOO according to the recommendations of Incontinence Control Society (ICS). The results showed that the UFA and Qmax in BPH group were much lower than those in the control group [(2.05±0.85) vs. (4.60±1.25) mL/s2 and (8.50±1.05) vs. (13.00±3.35) mL/s] (P〈0.001). Accol;ding to the criteria (UFA〈2.05 mL/s2, Qmax〈10 mL/s), the sensitivity and specificity of UFA vs. Qmax in diagnosing BOO were 88%, 75% vs. 81%, 63%. UFA vs. Omax, when compared with the results of P-Q chart (the kappa values in corresponding analysis), was 0.55 vs. 0.35. The pros- tate volume, post void residual and detrusor pressure at Qmax between the two groups were 28.6±9.8 vs. 24.2±7.6 mL, 60.4±1.4 vs. 21.3±2.5 mL and 56.6±8.3 vs. 21.7±6.1 cmHzO, respectively (P〈0.05). It was concluded that the UFA is a useful urodynamic parameter, and is superior to Qmax in diagnosing BOO in patients with BPH. 展开更多
关键词 benign prostate hyperplasia bph bladder outlet obstruction (BOO) urine flow accelera-tion (UFA) Qmax P-Q chart
下载PDF
Silodosin is effective for treatment of LUTS in men wii BPH: a systematic review 被引量:2
16
作者 Hui Ding Wan Du +2 位作者 Zi-Zhen Hou Han-Zhang Wang Zhi-Ping Wang 《Asian Journal of Andrology》 SCIE CAS CSCD 2013年第1期121-128,共8页
The aim of this study was to systematically review the evidence on the efficacy and safety of silodosin treatments on lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH) from randomi... The aim of this study was to systematically review the evidence on the efficacy and safety of silodosin treatments on lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH) from randomized controlled trials. We searched PubMed (1966- December 2011), Embase (1974-December 2011) and the Cochrane Library Database (2011, Issue 12). The assessed outcome measures were the change from baseline for the International Prostate Symptom Score (IPSS), quality of life (QoL) score, peak urine maximum flow rate (Qmax), QoL related to urinary symptoms and adverse effects. Two authors independently assessed the study quality and extracted data. All data were analysed using RevMan 5.1. The meta-analysis included four randomized controlled trials with a total of 2504 patients. The study durations were each 12 weeks. At the follow-up end points, the pooled results showed that the change from baseline for the silodosin group was significantly higher than the placebo group for the IPSS, QoL score and Qmax(mean difference (MD)=-2.78, P〈O.O0001; MD=-O.42, P--O.O04; MD= 1.17, P〈O.OOOOl,respectively) and patients felt more satisfied with QoL related to urinary symptoms in the silodosin group than the placebo group. Ejaculation disorder was the most commonly reported adverse effect. The pooled results also showed that the silodosin group was superior to the 0.2 mg tamsulosin group with respect to the IPSS and QoL score (IPSS: MD=- 1.14, P=O.02; QoL score: MD=-0.26, P=O.02) and inferior to the 0.2 mg tamsulosin group with respect to Qmax (MD=-0.85, P=O.01). In contrast, there was no significant difference in the incidence of ejaculation disorder and dizziness between the silodosin and 0.2 mg tamsulosin groups. The current meta-analysis suggested that silodosin is an effective therapy for LUTS in men with BPH and is not inferior to 0.2 mg tamsulosin. 展开更多
关键词 benign prostatic hyperplasia bph KMD-3213 lower urinary tract symptoms (LUTS) SILODOSIN TAMSULOSIN systematic review meta-analysis
下载PDF
Effect of Preoperative Dutasteride on Bleeding Related to Transurethral Resection of Prostate in Patients with Benign Prostatic Hyperplasia 被引量:2
17
作者 Md. Mostafiger Rahman Fatema-Tuj Johura +6 位作者 Md. Amanur Rasul Abul Kalam Mohammed Musa Bhuiyan Mohammad Ibrahim Ali Md. Sazzad Hossain Md. Kamrul Islam A. K. M. Shahidur Rahman Fahad Al Shatil Ashrafee 《Journal of Biosciences and Medicines》 2019年第5期157-169,共13页
Background: Transurethral resection of prostate (TURP) is the gold standard in the surgical treatment of symptomatic benign prostatic hyperplasia (BPH). Blood loss is one of the most common complications of TURP. Obje... Background: Transurethral resection of prostate (TURP) is the gold standard in the surgical treatment of symptomatic benign prostatic hyperplasia (BPH). Blood loss is one of the most common complications of TURP. Objective: To evaluate the effect of preoperative dutasteride on bleeding related to TURP in patients with BPH. Materials and Methods: This prospective interventional study was done in the department of urology, Dhaka Medical College Hospital, Dhaka, Bangladesh during the period of July 2016 to June 2017. A total of 70 cases of BPH planned for TURP were included in this study according to the statistical calculation. Patients were randomly allocated to control group A (TURP without dutasteride) and dutasteride group B (TURP with dutasteride). Each group consisted of 35 patients. Group B patients were treated with dutasteride 0.5 mg/day for 4 weeks before TURP. The main outcome of blood loss was evaluated in terms of reduction in serum hemoglobin (Hb) and hematocrit (Hct) levels, which were measured before and 24 hours after surgery. Data were analyzed and compared by statistical tests. Results: Comparison of outcome between groups shows that there was a significant difference in term of pre-post operative change of hemoglobin and hematocrit levels in the control group A compared to the dutasteride group B (Hb = 2.96 ± 0.80 gm/dl vs. 1.81 ± 0.71 gm/dl, respectively, p = 0.001;Hct = 11.20% ± 2.12% vs. 6.07% ± 2.02%, respectively, p = 0.02). A significant lower mean blood loss was observed in the dutasteride group compared to the control group. Conclusion: Preoperative dutasteride therapy reduces blood loss related to TURP in patients with BPH. This therapy can be practiced to reduce surgical bleeding associated with TURP. 展开更多
关键词 benign PROSTATIC HYPERPLASIA (bph) DUTASTERIDE TRANSURETHRAL Resection of Prostate (TURP)
下载PDF
Advances in Minimally Invasive Treatment of Benign Prostatic Hyperplasia 被引量:1
18
作者 Hang Xie Yuanhua Liu Jiang Zheng 《Journal of Biosciences and Medicines》 CAS 2022年第10期1-12,共12页
Benign prostatic hyperplasia (BPH) is a chronic condition that is more common in older men. BPH most commonly causes symptoms associated with LUTS and bladder outlet obstruction. Lower urinary tract symptoms (LUTS) in... Benign prostatic hyperplasia (BPH) is a chronic condition that is more common in older men. BPH most commonly causes symptoms associated with LUTS and bladder outlet obstruction. Lower urinary tract symptoms (LUTS) in men with BPH are a major cause of reduced quality of life in older men. If bladder outlet obstruction persists for a longer period of time, the contractility and voiding capacity of the detrusor muscle will gradually be affected by the obstructive factors, eventually leading to a loss of compensatory phase, characterised by a reduced electrical stimulation response, replacement of bladder muscle tissue by connective tissue, and a possible increase in voiding pressure, but a decrease in contractility of the detrusor muscle. As BOO progresses, it eventually leads to permanent contractile dysfunction of the detrusor muscle. Therefore, early initiation of surgical treatment in patients who are not well controlled by medication can reduce the complications associated with prostate enlargement. With the rise of minimally invasive treatment and the complications of open surgery, minimally invasive treatment of BPH has attracted increasing attention. Various emerging minimally invasive surgical modalities are being developed in clinical practice, and more and more minimally invasive techniques and concepts are focusing on safety, improving quality of life and reducing long-term complications to meet the different needs of different patients. Transurethral resection of the prostate (TURP) is currently the “gold standard” of minimally invasive surgical treatment, but with concerns about post-operative complications, the search for safer and more effective minimally invasive surgical options has become even more important. In recent years, with the increasing clinical application of new minimally invasive techniques such as various lasers, interventional treatments and implantable devices, there are more options for minimally invasive treatment of BPH. This article provides a brief review of research advances in the minimally invasive treatment of benign prostatic hyperplasia, with a view to informing clinical decisions. 展开更多
关键词 benign Prostatic Hyperplasia (bph) Minimally Invasive Treatments Therapeutic Efficacy SECURITY
下载PDF
A Review on Urinary Incontinence after Surgery for Benign Prostatic Hyperplasia 被引量:1
19
作者 Constantin Martial Essissima Foé Yunfen Liao Guoxi Zhang 《Open Journal of Urology》 2022年第3期169-184,共16页
Background: Benign prostatic hyperplasia (BPH) is characterized by the abnormal proliferation of cells, leading to structural changes. It is one of the most common diseases in ageing men. Its clinical presentations ar... Background: Benign prostatic hyperplasia (BPH) is characterized by the abnormal proliferation of cells, leading to structural changes. It is one of the most common diseases in ageing men. Its clinical presentations are dominated by lower urinary tract symptoms (LUTS). The therapeutic methods can be grouped into two options: the medical option and the surgical option in which prostate enucleation is found. In recent years many studies have reported the onset of urinary incontinence (UI) after prostate enucleation. The management of UI occurring after prostate enucleation is embarrassing for both the practitioner and the patient, and generates additional costs. Purpose: Cite the causes of UI after prostate enucleation for BPH, as well as ways to prevent the onset of UI after this surgery, specifically by the study of the vesicosphincteric system aimed at improving the technique of enucleation;our review will also deal with the therapeutic means of UI. Method: We retrieved studies from Science Direct, Wiley and Pubmed. Results: There are multiple etiologies of UI after prostate enucleation including urethral sphincter insufficiency (USI) and bladder dysfunction (BD). The management of UI after surgery could be conservative, surgical, or use new technologies. Urodynamic assessment before prostate enucleation for BPH is relevant. Conclusion: UI is a common post-operative complication of prostate enucleation. The study of the vesicosphincteric system leads us to believe that prostate enucleation for BPH, partially sparing the mucosa and the external urethral sphincter could decrease the incidence of UI after surgery. 展开更多
关键词 benign Prostatic Hyperplasia (bph) Urinary Incontinence (UI) Urethral Sphincter Insufficiency (USI) Bladder Dysfunction (BD) Detrusor Overactivity (DO) Prostate Enucleation
下载PDF
非那雄胺联合坦索罗辛治疗老年前列腺增生症(BPH)80例临床疗效观察 被引量:3
20
作者 厉凌峰 郭银燕 陈凡 《中国民康医学》 2014年第8期16-17,共2页
目的:观察非那雄胺联合坦索罗辛治疗前列腺增生症的临床疗效。方法:将80例患者随机分成两组,治疗组患者采用非那雄胺联合坦索罗辛治疗,对照组患者单用非那雄胺治疗。两组患者均治疗1年,分别在3个月、6个月与1年,分别记录IPSS评分,MFR前... 目的:观察非那雄胺联合坦索罗辛治疗前列腺增生症的临床疗效。方法:将80例患者随机分成两组,治疗组患者采用非那雄胺联合坦索罗辛治疗,对照组患者单用非那雄胺治疗。两组患者均治疗1年,分别在3个月、6个月与1年,分别记录IPSS评分,MFR前列腺体积和残余尿量等指标,比较两组临床疗效。结果:治疗组治疗后IPSS评分明显下降,最大尿流率升高,残余尿量减少,前列腺体积减小,以上指标均明显优于对照组;治疗组总有效率92.5%,高于对照组的72.5%,两者比较有统计学意义(P<0.05)。结论:非那雄胺联合坦索罗辛治疗前列腺增生症(BPH),可减轻前列腺症状,改善最大尿流率,减少尿潴留及前列腺源性血尿及手术干预的发生率。 展开更多
关键词 非那雄胺 坦索罗辛 前列腺增生症(bph)
下载PDF
上一页 1 2 19 下一页 到第
使用帮助 返回顶部