Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural safety.An active mass damper(AMD)with stroke limitations is often used to avoid collisions.However,a ...Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural safety.An active mass damper(AMD)with stroke limitations is often used to avoid collisions.However,a strokelimited AMD control system with a fixed limited area shortens the available AMD stroke and leads to significant control power.To solve this problem,the design approach with variable gain and limited area(VGLA)is proposed in this study.First,the boundary of variable-limited areas is calculated based on the real-time status of the moving mass.The variable gain(VG)expression at the variable limited area is deduced by considering the saturation of AMD stroke.Then,numerical simulations of a stroke-limited AMD control system with VGLA are conducted on a high-rise building structure.These numerical simulations show that the proposed approach has superior strokelimitation performance compared with a stroke-limited AMD control system with a fixed limited area.Finally,the proposed approach is validated through experiments on a four-story steel frame.展开更多
I.SUPPLEMENTARY NOTE 1:THEORETICAL MATERIALS.The quantum speed limit(QSL)is essential for quantum computing and quantum communication,referring to the minimum time required for a quantum system to evolve from one stat...I.SUPPLEMENTARY NOTE 1:THEORETICAL MATERIALS.The quantum speed limit(QSL)is essential for quantum computing and quantum communication,referring to the minimum time required for a quantum system to evolve from one state to another.Two well-known forms of the QSL are the Mandelstam-Tamm(MT)relation TqsL≥πh/2△E[S1]and the Margolus-Levitin(ML)relation TqsL≥πh/2(E)[S2]where Tqst is denoted as the QSL time,h is the reduced Planck's constant,△E is the energy uncertainty(standard deviation)of the system,and(E)is the average energy of the system above its ground state.Both of relations provide a lower bound on the evolution time.展开更多
Speed limit measures are ubiquitous due to the complexity of the road environment,which can be supplied with the help of vehicle to everything(V2X)communication technology.Therefore,the influence of speed limit on tra...Speed limit measures are ubiquitous due to the complexity of the road environment,which can be supplied with the help of vehicle to everything(V2X)communication technology.Therefore,the influence of speed limit on traffic system will be investigated to construct a two-lane lattice model accounting for the speed limit effect during the lane change process under V2X environment.Accordingly,the stability condition and the mKdV equation are closely associated with the speed limit effect through theory analysis.Moreover,the evolution of density and hysteresis loop is simulated to demonstrate the positive role of the speed limit effect on traffic stability in the cases of strong reaction intensity and high limited speed.展开更多
Phaeocystis globosa is an important unicellular eukaryotic alga that can also form colonies.P.globosa can cause massive harmful algal blooms and plays an important role in the global carbon or sulfur cycling.Thus far,...Phaeocystis globosa is an important unicellular eukaryotic alga that can also form colonies.P.globosa can cause massive harmful algal blooms and plays an important role in the global carbon or sulfur cycling.Thus far,the ecophysiology of P.globosa has been investigated by numerous studies.However,the proteomic response of P.globosa to nitrogen depletion remains largely unknown.We compared four protein preparation methods of P.globosa for two-dimensional electrophoresis(2-DE)(Urea/Triton X-100 with trichloroacetic acid(TCA)/acetone precipitation;TCA/acetone precipitation;Radio Immuno Precipitation Assay(RIPA)with TCA/acetone precipitation;and Tris buffer).Results show that the combination of RIPA with TCA/acetone precipitation had a clear gel background and showed the best protein spot separation effect,based on which the proteomic response to nitrogen depletion was studied using 2-DE.In addition,we identified six differentially expressed proteins whose relative abundance increased or decreased more than 1.5-fold(P<0.05).Most proteins could not be identified,which might be attributed to the lack of genomic sequences of P.globosa.Under nitrogen limitation,replication protein-like,RNA ligase,and sn-glycerol-3-phosphate dehydrogenase were reduced,which may decrease the DNA replication level and ATP production in P.globosa cells.The increase of endonucleaseⅢand transcriptional regulator enzyme may affect the metabolic and antioxidant function of P.globosa cells and induce cell apoptosis.These findings provide a basis for further proteomic study of P.globosa and the optimization of protein preparation methods of marine microalgae.展开更多
Planar sliding is one of the frequently observed types of failure in rock slopes.Kinematic analysis is a classic and widely used method to examine the potential failure modes in rock masses.The accuracy of planar slid...Planar sliding is one of the frequently observed types of failure in rock slopes.Kinematic analysis is a classic and widely used method to examine the potential failure modes in rock masses.The accuracy of planar sliding kinematic analysis is significantly influenced by the value assigned to the lateral limit angleγlim.However,the assignment ofγlim is currently used generally based on an empirical criterion.This study aims to propose an approach for determining the value ofγlim in deterministic and probabilistic kinematic planar sliding analysis.A new perspective is presented to reveal thatγlim essentially influences the probability of forming a potential planar sliding block.The procedure to calculate this probability is introduced using the block theory method.It is found that the probability is correlated with the number of discontinuity sets presented in rock masses.Thus,different values ofγlim for rock masses with different sets of discontinuities are recommended in both probabilistic and deterministic planar sliding kinematic analyses;whereas a fixed value ofγlim is commonly assigned to different types of rock masses in traditional method.Finally,an engineering case was used to compare the proposed and traditional kinematic analysis methods.The error rates of the traditional method vary from 45%to 119%,while that of the proposed method ranges between 1%and 17%.Therefore,it is likely that the proposed method is superior to the traditional one.展开更多
The problem considered in this short note is the limit load determination of a vertical rock slope.The classical limit theorem is employed with the use of adaptive finite elements and nonlinear programming to determin...The problem considered in this short note is the limit load determination of a vertical rock slope.The classical limit theorem is employed with the use of adaptive finite elements and nonlinear programming to determine upper and lower bound limit loads of a Hoek-Brown vertical rock slope.The objective function of the mathematical programming problem is such as to optimize a boundary load,which is known as the limit load,resembling the ultimate bearing capacity of a strip footing.While focusing on the vertical slope,parametric studies are carried out for several dimensionless ratios such as the dimensionless footing distance ratio,the dimensionless height ratio,and the dimensionless rock strength ratio.A comprehensive set of design charts is presented,and failure envelopes shown with the results explained in terms of three identified failure mechanisms,i.e.the face,the toe,and the Prandtl-type failures.These novel results can be used with great confidence in design practice,in particularly noting that the current industry-based design procedures for the presented problem are rarely found.展开更多
Existing studies have focused on the behavior of the retaining wall equipped with expanded polystyrene(EPS)geofoam inclusions under semi-infinite surcharge loading rather than limited surcharge loading.In this paper,t...Existing studies have focused on the behavior of the retaining wall equipped with expanded polystyrene(EPS)geofoam inclusions under semi-infinite surcharge loading rather than limited surcharge loading.In this paper,the failure mode and the earth pressure acting on the rigid retaining wall with EPS geofoam inclusions and granular backfills(henceforth referred to as EPS-wall),under limited surcharge loading are investigated through two-and three-dimensional model tests.The testing results show that different from the sliding of almost all the backfill in the EPS-wall under semi-infinite surcharge loading,only an approximately triangular backfill slides in the wall under limited surcharge loading.The distribution of the lateral earth pressure on the EPS-wall under limited surcharge loading is non-linear,and the distribution changes from the increase of the wall depth to the decrease with the increase of the limited surcharge loading.An approach based on the force equilibrium of a differential element is developed to predict the lateral earth pressure behind the EPS-wall subjected to limited surcharge loading,and its performance was fully validated by the three-dimensional model tests.展开更多
In recent years, numerous theoretical tandem mass spectrometry prediction methods have been proposed, yet a systematic study and evaluation of their theoretical accuracy limits have not been conducted. If the accuracy...In recent years, numerous theoretical tandem mass spectrometry prediction methods have been proposed, yet a systematic study and evaluation of their theoretical accuracy limits have not been conducted. If the accuracy of current methods approaches this limit, further exploration of new prediction techniques may become redundant. Conversely, a need for more precise prediction methods or models may be indicated. In this study, we have experimentally analyzed the limits of accuracy at different numbers of ions and parameters using repeated spectral pairs and integrating various similarity metrics. Results show significant achievements in accuracy for backbone ion methods with room for improvement. In contrast, full-spectrum prediction methods exhibit greater potential relative to the theoretical accuracy limit. Additionally, findings highlight the significant impact of normalized collision energy and instrument type on prediction accuracy, underscoring the importance of considering these factors in future theoretical tandem mass spectrometry predictions.展开更多
This paper explores the problem of distributed Nash equilibrium seeking in games, where players have limited knowledge on other players' actions. In particular, the involved players are considered to be high-order...This paper explores the problem of distributed Nash equilibrium seeking in games, where players have limited knowledge on other players' actions. In particular, the involved players are considered to be high-order integrators with their control inputs constrained within a pre-specified region. A linear transformation for players' dynamics is firstly utilized to facilitate the design of bounded control inputs incorporating multiple saturation functions. By introducing consensus protocols with adaptive and time-varying gains, the unknown actions for players are distributively estimated. Then, a fully distributed Nash equilibrium seeking strategy is exploited, showcasing its remarkable properties: (1) ensuring the boundedness of control inputs;(2) avoiding any global information/parameters;and (3) allowing the graph to be directed. Based on Lyapunov stability analysis, it is theoretically proved that the proposed distributed control strategy can lead all the players' actions to the Nash equilibrium. Finally, an illustrative example is given to validate effectiveness of the proposed method.展开更多
Expected to be of the highest survey power telescope in the northern hemisphere,the Wide Field Survey Telescope(WFST)will begin its routine observations of the northern sky since 2023.WFST will produce a lot of scient...Expected to be of the highest survey power telescope in the northern hemisphere,the Wide Field Survey Telescope(WFST)will begin its routine observations of the northern sky since 2023.WFST will produce a lot of scientific data to support the researches of time-domain astronomy,asteroids and the solar system,galaxy formation and cosmology and so on.We estimated that the 5σlimiting magnitudes of WFST with 30 s exposure are u=22.31mag,g=23.42 mag,r=22.95 mag,i=22.43 mag,z=21.50 mag,w=23.61 mag.The above values are calculated for the conditions of airmass=1.2,seeing=075,precipitable water vapor=2.5 mm and Moon-object separation=45°at the darkest New Moon night of the Lenghu site(V=22.30 mag,Moon phaseθ=0°).The limiting magnitudes in different Moon phase conditions are also calculated.The calculations are based on the empirical transmittance data of WFST optics,the vendor provided CCD quantum efficiency,the atmospherical model transmittance and spectrum of the site.In the absence of measurement data such as sky transmittance and spectrum,we use model data.展开更多
INTRODUCTION The Italian anatomist Filippo Pacini discovered the internal limiting membrane(ILM) in 1844[1]. The ILM is the basement membrane of the retinal Müller cells representing the structural interface betw...INTRODUCTION The Italian anatomist Filippo Pacini discovered the internal limiting membrane(ILM) in 1844[1]. The ILM is the basement membrane of the retinal Müller cells representing the structural interface between the retina and the vitreous. The macular ILM is thickest, measuring 2.5 μm and progressively thins to 0.5 μm at the vitreous base[2].展开更多
The resorption of nutrients by plants before litter fall and the mineralization of nutrients from plant litter by soil processes are both important pathways supporting primary productivity. While the positive relation...The resorption of nutrients by plants before litter fall and the mineralization of nutrients from plant litter by soil processes are both important pathways supporting primary productivity. While the positive relationship between plant biodiversity and primary productivity is widely accepted for natural ecosystems, the roles of nutrient resorption and mineralization in mediating that relationship remains largely unknown. Here, we quantified the relative importance of nitrogen(N) resorption and N mineralization in driving plant community N investment and the correlation between species diversity and community productivity along an N-limited successional chronosequence of the mixed broadleaved–Korean pine(Pinus koraiensis) forest in northeastern China. Leaf N resorption efficiency(NRE) at the community level increased significantly along the successional chronosequence,whereas litter N mineralization rate decreased significantly. Leaf NRE was more important than litter N mineralization rate in driving the diversity–productivity relationship. However, higher leaf NRE led to less N mineralization as succession progressed along the chronosequence. Our results highlight the importance of the N resorption pathway rather than the N mineralization pathway for forest N acquisition with community succession,and they provide mechanistic insights into the positive effects of biodiversity on ecosystem functioning. In future forest management practices, we recommend appropriate application of N fertilizer to mitigate the adverse effects of N-poor soil on seedling regeneration during late succession and thus maintain the sustainable development of temperate forest ecosystems.展开更多
We study the strong nonlinear optical dynamics of nanosecond pulsed Laguerre–Gaussian laser beams of high-order radial modes with zero orbital angular momentum propagating in the fullerene C60molecular medium. It is ...We study the strong nonlinear optical dynamics of nanosecond pulsed Laguerre–Gaussian laser beams of high-order radial modes with zero orbital angular momentum propagating in the fullerene C60molecular medium. It is found that the spatiotemporal profile of the incident pulsed Laguerre–Gaussian laser beam is strongly reshaped during its propagation in the C60molecular medium. The centrosymmetric temporal profile of the incident pulse gradually evolves into a noncentrosymmetric meniscus shape, and the on-axis pulse duration is clearly depressed. Furthermore, the field intensity is distinctly attenuated due to the field-intensity-dependent reverse saturable absorption, and clear optical power limiting behavior is observed for different orders of the input pulsed Laguerre–Gaussian laser beams before the takeover of the saturation effect;the lower the order of the Laguerre–Gaussian beam, the lower the energy transmittance.展开更多
In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are ...In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are integrated into the electronic controller only from the pump level,leading to the potential instability of the overall system.To solve this problem,a multi-mode electrohydraulic load sensing(MELS)control scheme is proposed especially considering the switching stability from the system level,which includes four working modes of flow control,load sensing,power limitation,and pressure control.Depending on the actual working requirements,the switching rules for the different modes and the switching direction(i.e.,the modes can be switched bilaterally or unilaterally)are defined.The priority of different modes is also defined,from high to low:pressure control,power limitation,load sensing,and flow control.When multiple switching rules are satisfied at the same time,the system switches to the control mode with the highest priority.In addition,the switching stability between flow control and pressure control modes is analyzed,and the controller parameters that guarantee the switching stability are obtained.A comparative study is carried out based on a test rig with a 2-ton hydraulic excavator.The results show that the MELS controller can achieve the control functions of proper flow supplement,power limitation,and pressure cut-off,which has good stability performance when switching between different control modes.This research proposes the MELS control method that realizes the stability of multi-mode switching of the hydraulic system of mobile machinery under different working conditions.展开更多
We investigate the global classical solutions of the non-relativistic Vlasov-D arwin system with generalized variables(VDG)in three dimensions.We first prove the global existence and uniqueness for small initial data ...We investigate the global classical solutions of the non-relativistic Vlasov-D arwin system with generalized variables(VDG)in three dimensions.We first prove the global existence and uniqueness for small initial data and derive the decay estimates of the Darwin potentials.Then,we show in this framework that the solutions converge in a pointwise sense to solutions of the classical Vlasov-Poisson system(VP)at the asymptotic rate of 1/c2 as the speed of light c tends to infinity for all time.Moreover,we obtain rigorously an asymptotic estimate of the difference between the two systems.展开更多
In this paper,we study the zero dissipation limit with a vacuum for the reacting mixture Navier-Stokes equations.For proper smooth initial data that the initial density tends to zero as the relevant physical coefficie...In this paper,we study the zero dissipation limit with a vacuum for the reacting mixture Navier-Stokes equations.For proper smooth initial data that the initial density tends to zero as the relevant physical coefficients tend to zero,we demonstrate that the solution tends to a rarefaction wave connected to a vacuum on the left side coupled with a zero mass fraction of reactant.What is more,the uniform convergence rate is obtained.展开更多
Recent works have shown that neural networks are promising parameter-free limiters for a variety of numerical schemes(Morgan et al.in A machine learning approach for detect-ing shocks with high-order hydrodynamic meth...Recent works have shown that neural networks are promising parameter-free limiters for a variety of numerical schemes(Morgan et al.in A machine learning approach for detect-ing shocks with high-order hydrodynamic methods.et al.in J Comput Phys 367:166-191.,2018;Veiga et al.in European Conference on Computational Mechanics andⅦEuropean Conference on Computational Fluid Dynamics,vol.1,pp.2525-2550.ECCM.,2018).Following this trend,we train a neural network to serve as a shock-indicator function using simulation data from a Runge-Kutta discontinuous Galer-kin(RKDG)method and a modal high-order limiter(Krivodonova in J Comput Phys 226:879-896.,2007).With this methodology,we obtain one-and two-dimensional black-box shock-indicators which are then coupled to a standard limiter.Furthermore,we describe a strategy to transfer the shock-indicator to a residual distribution(RD)scheme without the need for a full training cycle and large data-set,by finding a mapping between the solution feature spaces from an RD scheme to an RKDG scheme,both in one-and two-dimensional problems,and on Cartesian and unstruc-tured meshes.We report on the quality of the numerical solutions when using the neural network shock-indicator coupled to a limiter,comparing its performance to traditional lim-iters,for both RKDG and RD schemes.展开更多
In this paper, we consider the second-grade fluid equations in a 2D exterior domain satisfying the non-slip boundary conditions. The second-grade fluid model is a wellknown non-Newtonian fluid model, with two paramete...In this paper, we consider the second-grade fluid equations in a 2D exterior domain satisfying the non-slip boundary conditions. The second-grade fluid model is a wellknown non-Newtonian fluid model, with two parameters: α, which represents the length-scale,while ν > 0 corresponds to the viscosity. We prove that, as ν, α tend to zero, the solution of the second-grade fluid equations with suitable initial data converges to the one of Euler equations, provided that ν = o(α^(4/3)). Moreover, the convergent rate is obtained.展开更多
We study the ground states of attractive binary Bose-Einstein condensates with N particles,which are trapped in the steep potential wellsλV(x)inℝ2.We show that there exists a positive number N*such that if N>N*,th...We study the ground states of attractive binary Bose-Einstein condensates with N particles,which are trapped in the steep potential wellsλV(x)inℝ2.We show that there exists a positive number N*such that if N>N*,the system admits no ground state for anyλ>0.Moreover,there exist two positive numbers,M*andλ*(N),such that if N<M*,then for anyλ>λ*(N),the system admits at least one ground state.Asλ→∞,for any fixed N<M*,we give a detailed description for the limit behavior of both positive and semi-trivial ground states.展开更多
Buruli ulcer (BU) is a chronic, indolent necrotizing disease of the skin and underlying tissues caused by Mycobacterium ulcerans, which may result in functional disability. This disease is the third most frequent infe...Buruli ulcer (BU) is a chronic, indolent necrotizing disease of the skin and underlying tissues caused by Mycobacterium ulcerans, which may result in functional disability. This disease is the third most frequent infection after leprosy and tuberculosis caused by a mycobacterium. The main objective of this study was to determine comparative effectiveness of conventional physiotherapy alone to its association with Kabat’s method in the management of post-Buruli ulcer functional limitations. This was an interventional randomized, comparative and prospective study. It took place at the district hospital of Akonolinga from the 12<sup>th</sup> June to 12<sup>th</sup> September 2016. The study was included, post-Buruli ulcer patients who matched the eligibility criteria, were under treatment in the physiotherapy unit, and who accepted to participate in our study. A questionnaire on the socio-demographic profile of participants, the ulcer localization, the limitation stage, previous medical history and functional mobility assessment scale was administered to the subjects before and after the intervention which lasted for twelve weeks. We had 2 groups: the case group received association of Kabat technique to conventional physiotherapy and the control group received conventional physiotherapy alone. We had 22 patients, 11 patients for the experimental group, 11 patients for the control group. The mean age was 26.18 years, 54.5% of female participation, 68.2% of leg localization, 59.1% patients with severe limitations of functional mobility, and preference for traditional medication 95.5%. After evaluation of efficiency, we concluded that there was no statistically significant difference between the two treatment protocols. Further studies with larger sample size are recommended.展开更多
基金This research was founded by the Funds for Creative Research Groups of National Natural Science Foundation of China(Grant No.51921006)the National Natural Science Foundations of China(Grant No.51978224)+2 种基金the National Major Scientific Research Instrument Development Program of China(Grant No.51827811)the National Natural Science Foundation of China,(Grant No.52008141)the Shenzhen Technology Innovation Program(Grant Nos.JCYJ20170811160003571,JCYJ20180508152238111 and JCYJ20200109112803851).
文摘Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural safety.An active mass damper(AMD)with stroke limitations is often used to avoid collisions.However,a strokelimited AMD control system with a fixed limited area shortens the available AMD stroke and leads to significant control power.To solve this problem,the design approach with variable gain and limited area(VGLA)is proposed in this study.First,the boundary of variable-limited areas is calculated based on the real-time status of the moving mass.The variable gain(VG)expression at the variable limited area is deduced by considering the saturation of AMD stroke.Then,numerical simulations of a stroke-limited AMD control system with VGLA are conducted on a high-rise building structure.These numerical simulations show that the proposed approach has superior strokelimitation performance compared with a stroke-limited AMD control system with a fixed limited area.Finally,the proposed approach is validated through experiments on a four-story steel frame.
基金supported by the National Natural Science Foundation of China(Grant Nos.92165206 and 11974330)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0301603)the Fundamental Research Funds for the Central Universities。
文摘I.SUPPLEMENTARY NOTE 1:THEORETICAL MATERIALS.The quantum speed limit(QSL)is essential for quantum computing and quantum communication,referring to the minimum time required for a quantum system to evolve from one state to another.Two well-known forms of the QSL are the Mandelstam-Tamm(MT)relation TqsL≥πh/2△E[S1]and the Margolus-Levitin(ML)relation TqsL≥πh/2(E)[S2]where Tqst is denoted as the QSL time,h is the reduced Planck's constant,△E is the energy uncertainty(standard deviation)of the system,and(E)is the average energy of the system above its ground state.Both of relations provide a lower bound on the evolution time.
基金Project supported by the Guangxi Natural Science Foundation,China(Grant No.2022GXNSFDA035080)the Central Government Guidance Funds for Local Scientific and Technological Development,China(Grant No.Guike ZY22096024)the National Natural Science Foundation,China(Grant No.61963008).
文摘Speed limit measures are ubiquitous due to the complexity of the road environment,which can be supplied with the help of vehicle to everything(V2X)communication technology.Therefore,the influence of speed limit on traffic system will be investigated to construct a two-lane lattice model accounting for the speed limit effect during the lane change process under V2X environment.Accordingly,the stability condition and the mKdV equation are closely associated with the speed limit effect through theory analysis.Moreover,the evolution of density and hysteresis loop is simulated to demonstrate the positive role of the speed limit effect on traffic stability in the cases of strong reaction intensity and high limited speed.
基金the National Natural Science Foundation of China(Nos.42176142,41906111,41806127)the Marine Economic Development Project of Guangdong Province(No.2023B1111050011)+1 种基金the Basic and Applied Basic Research Project of Guangzhou(Nos.2023A04J1548,2023A04J1549)the Outstanding Innovative Talents Cultivation Funded Programs for Doctoral Students of Jinan University(No.2021CXB010)。
文摘Phaeocystis globosa is an important unicellular eukaryotic alga that can also form colonies.P.globosa can cause massive harmful algal blooms and plays an important role in the global carbon or sulfur cycling.Thus far,the ecophysiology of P.globosa has been investigated by numerous studies.However,the proteomic response of P.globosa to nitrogen depletion remains largely unknown.We compared four protein preparation methods of P.globosa for two-dimensional electrophoresis(2-DE)(Urea/Triton X-100 with trichloroacetic acid(TCA)/acetone precipitation;TCA/acetone precipitation;Radio Immuno Precipitation Assay(RIPA)with TCA/acetone precipitation;and Tris buffer).Results show that the combination of RIPA with TCA/acetone precipitation had a clear gel background and showed the best protein spot separation effect,based on which the proteomic response to nitrogen depletion was studied using 2-DE.In addition,we identified six differentially expressed proteins whose relative abundance increased or decreased more than 1.5-fold(P<0.05).Most proteins could not be identified,which might be attributed to the lack of genomic sequences of P.globosa.Under nitrogen limitation,replication protein-like,RNA ligase,and sn-glycerol-3-phosphate dehydrogenase were reduced,which may decrease the DNA replication level and ATP production in P.globosa cells.The increase of endonucleaseⅢand transcriptional regulator enzyme may affect the metabolic and antioxidant function of P.globosa cells and induce cell apoptosis.These findings provide a basis for further proteomic study of P.globosa and the optimization of protein preparation methods of marine microalgae.
基金funded by National Natural Science Foundation,China(Grant Nos.41972264 and 42207214)Zhejiang Provincial Natural Science Foundation,China(Grant No.LR22E080002).
文摘Planar sliding is one of the frequently observed types of failure in rock slopes.Kinematic analysis is a classic and widely used method to examine the potential failure modes in rock masses.The accuracy of planar sliding kinematic analysis is significantly influenced by the value assigned to the lateral limit angleγlim.However,the assignment ofγlim is currently used generally based on an empirical criterion.This study aims to propose an approach for determining the value ofγlim in deterministic and probabilistic kinematic planar sliding analysis.A new perspective is presented to reveal thatγlim essentially influences the probability of forming a potential planar sliding block.The procedure to calculate this probability is introduced using the block theory method.It is found that the probability is correlated with the number of discontinuity sets presented in rock masses.Thus,different values ofγlim for rock masses with different sets of discontinuities are recommended in both probabilistic and deterministic planar sliding kinematic analyses;whereas a fixed value ofγlim is commonly assigned to different types of rock masses in traditional method.Finally,an engineering case was used to compare the proposed and traditional kinematic analysis methods.The error rates of the traditional method vary from 45%to 119%,while that of the proposed method ranges between 1%and 17%.Therefore,it is likely that the proposed method is superior to the traditional one.
基金This research was funded by National Science,Research and Innovation Fund(NSRF),and King Mongkut’s University of Technology North Bangkok with Contract No.KMUTNBeFFe66e12.
文摘The problem considered in this short note is the limit load determination of a vertical rock slope.The classical limit theorem is employed with the use of adaptive finite elements and nonlinear programming to determine upper and lower bound limit loads of a Hoek-Brown vertical rock slope.The objective function of the mathematical programming problem is such as to optimize a boundary load,which is known as the limit load,resembling the ultimate bearing capacity of a strip footing.While focusing on the vertical slope,parametric studies are carried out for several dimensionless ratios such as the dimensionless footing distance ratio,the dimensionless height ratio,and the dimensionless rock strength ratio.A comprehensive set of design charts is presented,and failure envelopes shown with the results explained in terms of three identified failure mechanisms,i.e.the face,the toe,and the Prandtl-type failures.These novel results can be used with great confidence in design practice,in particularly noting that the current industry-based design procedures for the presented problem are rarely found.
基金funding support from National Natural Science Foundation of China(Grant No.52179109)Jiangsu Provincial Natural Science Foundation(Grant No.BK20230967)Open Research Fund of State Key Laboratory of Mechanical Behavior and System Safety of Traffic Engineering Structures,Shijiazhuang Tiedao University(Grant No.KF2022-02).
文摘Existing studies have focused on the behavior of the retaining wall equipped with expanded polystyrene(EPS)geofoam inclusions under semi-infinite surcharge loading rather than limited surcharge loading.In this paper,the failure mode and the earth pressure acting on the rigid retaining wall with EPS geofoam inclusions and granular backfills(henceforth referred to as EPS-wall),under limited surcharge loading are investigated through two-and three-dimensional model tests.The testing results show that different from the sliding of almost all the backfill in the EPS-wall under semi-infinite surcharge loading,only an approximately triangular backfill slides in the wall under limited surcharge loading.The distribution of the lateral earth pressure on the EPS-wall under limited surcharge loading is non-linear,and the distribution changes from the increase of the wall depth to the decrease with the increase of the limited surcharge loading.An approach based on the force equilibrium of a differential element is developed to predict the lateral earth pressure behind the EPS-wall subjected to limited surcharge loading,and its performance was fully validated by the three-dimensional model tests.
文摘In recent years, numerous theoretical tandem mass spectrometry prediction methods have been proposed, yet a systematic study and evaluation of their theoretical accuracy limits have not been conducted. If the accuracy of current methods approaches this limit, further exploration of new prediction techniques may become redundant. Conversely, a need for more precise prediction methods or models may be indicated. In this study, we have experimentally analyzed the limits of accuracy at different numbers of ions and parameters using repeated spectral pairs and integrating various similarity metrics. Results show significant achievements in accuracy for backbone ion methods with room for improvement. In contrast, full-spectrum prediction methods exhibit greater potential relative to the theoretical accuracy limit. Additionally, findings highlight the significant impact of normalized collision energy and instrument type on prediction accuracy, underscoring the importance of considering these factors in future theoretical tandem mass spectrometry predictions.
基金supported by the National Natural Science Foundation of China(62222308,62173181,62073171,62221004)the Natural Science Foundation of Jiangsu Province(BK20220139,BK20200744)+3 种基金Jiangsu Specially-Appointed Professor(RK043STP19001)the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(CAST)(2021QNRC001)1311 Talent Plan of Nanjing University of Posts and Telecommunicationsthe Fundamental Research Funds for the Central Universities(30920032203)。
文摘This paper explores the problem of distributed Nash equilibrium seeking in games, where players have limited knowledge on other players' actions. In particular, the involved players are considered to be high-order integrators with their control inputs constrained within a pre-specified region. A linear transformation for players' dynamics is firstly utilized to facilitate the design of bounded control inputs incorporating multiple saturation functions. By introducing consensus protocols with adaptive and time-varying gains, the unknown actions for players are distributively estimated. Then, a fully distributed Nash equilibrium seeking strategy is exploited, showcasing its remarkable properties: (1) ensuring the boundedness of control inputs;(2) avoiding any global information/parameters;and (3) allowing the graph to be directed. Based on Lyapunov stability analysis, it is theoretically proved that the proposed distributed control strategy can lead all the players' actions to the Nash equilibrium. Finally, an illustrative example is given to validate effectiveness of the proposed method.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(grant Nos.XDB 41000000 and XDB 41010105)the National Science Foundation of China(NSFC,grant Nos.12233008,12173037 and 11973038)+1 种基金the China Manned Space Project(No.CMS-CSST-2021-A07)the Cyrus Chun Ying Tang Foundations。
文摘Expected to be of the highest survey power telescope in the northern hemisphere,the Wide Field Survey Telescope(WFST)will begin its routine observations of the northern sky since 2023.WFST will produce a lot of scientific data to support the researches of time-domain astronomy,asteroids and the solar system,galaxy formation and cosmology and so on.We estimated that the 5σlimiting magnitudes of WFST with 30 s exposure are u=22.31mag,g=23.42 mag,r=22.95 mag,i=22.43 mag,z=21.50 mag,w=23.61 mag.The above values are calculated for the conditions of airmass=1.2,seeing=075,precipitable water vapor=2.5 mm and Moon-object separation=45°at the darkest New Moon night of the Lenghu site(V=22.30 mag,Moon phaseθ=0°).The limiting magnitudes in different Moon phase conditions are also calculated.The calculations are based on the empirical transmittance data of WFST optics,the vendor provided CCD quantum efficiency,the atmospherical model transmittance and spectrum of the site.In the absence of measurement data such as sky transmittance and spectrum,we use model data.
文摘INTRODUCTION The Italian anatomist Filippo Pacini discovered the internal limiting membrane(ILM) in 1844[1]. The ILM is the basement membrane of the retinal Müller cells representing the structural interface between the retina and the vitreous. The macular ILM is thickest, measuring 2.5 μm and progressively thins to 0.5 μm at the vitreous base[2].
基金financially supported by the National Natural Science Foundation of China(No.32071533)the Fundamental Research Funds for the Central Universities,China(2572020AW13)。
文摘The resorption of nutrients by plants before litter fall and the mineralization of nutrients from plant litter by soil processes are both important pathways supporting primary productivity. While the positive relationship between plant biodiversity and primary productivity is widely accepted for natural ecosystems, the roles of nutrient resorption and mineralization in mediating that relationship remains largely unknown. Here, we quantified the relative importance of nitrogen(N) resorption and N mineralization in driving plant community N investment and the correlation between species diversity and community productivity along an N-limited successional chronosequence of the mixed broadleaved–Korean pine(Pinus koraiensis) forest in northeastern China. Leaf N resorption efficiency(NRE) at the community level increased significantly along the successional chronosequence,whereas litter N mineralization rate decreased significantly. Leaf NRE was more important than litter N mineralization rate in driving the diversity–productivity relationship. However, higher leaf NRE led to less N mineralization as succession progressed along the chronosequence. Our results highlight the importance of the N resorption pathway rather than the N mineralization pathway for forest N acquisition with community succession,and they provide mechanistic insights into the positive effects of biodiversity on ecosystem functioning. In future forest management practices, we recommend appropriate application of N fertilizer to mitigate the adverse effects of N-poor soil on seedling regeneration during late succession and thus maintain the sustainable development of temperate forest ecosystems.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11974108 and 11574082)Fundamental Research Funds for the Central Universities (Grant No. 2021MS046)the Natural Science Foundation of Shandong Province, China (Grant No. ZR2019MA020)。
文摘We study the strong nonlinear optical dynamics of nanosecond pulsed Laguerre–Gaussian laser beams of high-order radial modes with zero orbital angular momentum propagating in the fullerene C60molecular medium. It is found that the spatiotemporal profile of the incident pulsed Laguerre–Gaussian laser beam is strongly reshaped during its propagation in the C60molecular medium. The centrosymmetric temporal profile of the incident pulse gradually evolves into a noncentrosymmetric meniscus shape, and the on-axis pulse duration is clearly depressed. Furthermore, the field intensity is distinctly attenuated due to the field-intensity-dependent reverse saturable absorption, and clear optical power limiting behavior is observed for different orders of the input pulsed Laguerre–Gaussian laser beams before the takeover of the saturation effect;the lower the order of the Laguerre–Gaussian beam, the lower the energy transmittance.
基金National Key Research and Development Program of China(Grant No.2020YFB2009702)National Natural Science Foundation of China(Grant Nos.52075055,U21A20124 and 52111530069)Chongqing Natural Science Foundation of China(Grant No.cstc2020jcyj-msxmX0780)。
文摘In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are integrated into the electronic controller only from the pump level,leading to the potential instability of the overall system.To solve this problem,a multi-mode electrohydraulic load sensing(MELS)control scheme is proposed especially considering the switching stability from the system level,which includes four working modes of flow control,load sensing,power limitation,and pressure control.Depending on the actual working requirements,the switching rules for the different modes and the switching direction(i.e.,the modes can be switched bilaterally or unilaterally)are defined.The priority of different modes is also defined,from high to low:pressure control,power limitation,load sensing,and flow control.When multiple switching rules are satisfied at the same time,the system switches to the control mode with the highest priority.In addition,the switching stability between flow control and pressure control modes is analyzed,and the controller parameters that guarantee the switching stability are obtained.A comparative study is carried out based on a test rig with a 2-ton hydraulic excavator.The results show that the MELS controller can achieve the control functions of proper flow supplement,power limitation,and pressure cut-off,which has good stability performance when switching between different control modes.This research proposes the MELS control method that realizes the stability of multi-mode switching of the hydraulic system of mobile machinery under different working conditions.
基金supported by the National Natural ScienceFoundation of China(11871024)the Fundamental Research Program of Shanxi Province(202103021223182)。
文摘We investigate the global classical solutions of the non-relativistic Vlasov-D arwin system with generalized variables(VDG)in three dimensions.We first prove the global existence and uniqueness for small initial data and derive the decay estimates of the Darwin potentials.Then,we show in this framework that the solutions converge in a pointwise sense to solutions of the classical Vlasov-Poisson system(VP)at the asymptotic rate of 1/c2 as the speed of light c tends to infinity for all time.Moreover,we obtain rigorously an asymptotic estimate of the difference between the two systems.
基金supported by the National Natural Science Foundation of China (11971193 and 12171001)。
文摘In this paper,we study the zero dissipation limit with a vacuum for the reacting mixture Navier-Stokes equations.For proper smooth initial data that the initial density tends to zero as the relevant physical coefficients tend to zero,we demonstrate that the solution tends to a rarefaction wave connected to a vacuum on the left side coupled with a zero mass fraction of reactant.What is more,the uniform convergence rate is obtained.
文摘Recent works have shown that neural networks are promising parameter-free limiters for a variety of numerical schemes(Morgan et al.in A machine learning approach for detect-ing shocks with high-order hydrodynamic methods.et al.in J Comput Phys 367:166-191.,2018;Veiga et al.in European Conference on Computational Mechanics andⅦEuropean Conference on Computational Fluid Dynamics,vol.1,pp.2525-2550.ECCM.,2018).Following this trend,we train a neural network to serve as a shock-indicator function using simulation data from a Runge-Kutta discontinuous Galer-kin(RKDG)method and a modal high-order limiter(Krivodonova in J Comput Phys 226:879-896.,2007).With this methodology,we obtain one-and two-dimensional black-box shock-indicators which are then coupled to a standard limiter.Furthermore,we describe a strategy to transfer the shock-indicator to a residual distribution(RD)scheme without the need for a full training cycle and large data-set,by finding a mapping between the solution feature spaces from an RD scheme to an RKDG scheme,both in one-and two-dimensional problems,and on Cartesian and unstruc-tured meshes.We report on the quality of the numerical solutions when using the neural network shock-indicator coupled to a limiter,comparing its performance to traditional lim-iters,for both RKDG and RD schemes.
基金Aibin Zang was supported partially by the National Natural Science Foundation of China (11771382, 12061080, 12261093)the Jiangxi Provincial Natural Science Foundation (20224ACB201004)。
文摘In this paper, we consider the second-grade fluid equations in a 2D exterior domain satisfying the non-slip boundary conditions. The second-grade fluid model is a wellknown non-Newtonian fluid model, with two parameters: α, which represents the length-scale,while ν > 0 corresponds to the viscosity. We prove that, as ν, α tend to zero, the solution of the second-grade fluid equations with suitable initial data converges to the one of Euler equations, provided that ν = o(α^(4/3)). Moreover, the convergent rate is obtained.
基金supported by NSFC(12075102 and 11971212)the Fundamental Research Funds for the Central Universities(lzujbky-2020-pd01)。
文摘We study the ground states of attractive binary Bose-Einstein condensates with N particles,which are trapped in the steep potential wellsλV(x)inℝ2.We show that there exists a positive number N*such that if N>N*,the system admits no ground state for anyλ>0.Moreover,there exist two positive numbers,M*andλ*(N),such that if N<M*,then for anyλ>λ*(N),the system admits at least one ground state.Asλ→∞,for any fixed N<M*,we give a detailed description for the limit behavior of both positive and semi-trivial ground states.
文摘Buruli ulcer (BU) is a chronic, indolent necrotizing disease of the skin and underlying tissues caused by Mycobacterium ulcerans, which may result in functional disability. This disease is the third most frequent infection after leprosy and tuberculosis caused by a mycobacterium. The main objective of this study was to determine comparative effectiveness of conventional physiotherapy alone to its association with Kabat’s method in the management of post-Buruli ulcer functional limitations. This was an interventional randomized, comparative and prospective study. It took place at the district hospital of Akonolinga from the 12<sup>th</sup> June to 12<sup>th</sup> September 2016. The study was included, post-Buruli ulcer patients who matched the eligibility criteria, were under treatment in the physiotherapy unit, and who accepted to participate in our study. A questionnaire on the socio-demographic profile of participants, the ulcer localization, the limitation stage, previous medical history and functional mobility assessment scale was administered to the subjects before and after the intervention which lasted for twelve weeks. We had 2 groups: the case group received association of Kabat technique to conventional physiotherapy and the control group received conventional physiotherapy alone. We had 22 patients, 11 patients for the experimental group, 11 patients for the control group. The mean age was 26.18 years, 54.5% of female participation, 68.2% of leg localization, 59.1% patients with severe limitations of functional mobility, and preference for traditional medication 95.5%. After evaluation of efficiency, we concluded that there was no statistically significant difference between the two treatment protocols. Further studies with larger sample size are recommended.