The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biologi...The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biological activities, including anti-inflammatory, immunomodulatory, anti-tumour, antimalarial, antinociceptive, antimierobial and other activities. In this review, we comprehensively summarized the progress concerning the phytochemistry and biological activities of sesquiterpenoids obtained from the Artemisia species from 2010 to July 2016. Furthermore, several future research perspectives and development of sesquiterpenoids as potential therapeutic agents were discussed as well.展开更多
基金National Natural Science Foundation of China(Grant No.31400305 and 81202916)the Science and Technology Project of Henan Province(Grant No.152102310113)+1 种基金the Science and Technology Project of the Education Department of Henan Province(Grant No.14A360012)the Project for Youth Backbone Teachers in the University of Henan Province(Grant No.2015GGJS-130)
文摘The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biological activities, including anti-inflammatory, immunomodulatory, anti-tumour, antimalarial, antinociceptive, antimierobial and other activities. In this review, we comprehensively summarized the progress concerning the phytochemistry and biological activities of sesquiterpenoids obtained from the Artemisia species from 2010 to July 2016. Furthermore, several future research perspectives and development of sesquiterpenoids as potential therapeutic agents were discussed as well.