To explore the influence of compound bioelectret material′s dielectric property on the cell growth,several kinds of compound bioelectret materials of collagen/chitosan were developed Their TSDC(thermally stimulated ...To explore the influence of compound bioelectret material′s dielectric property on the cell growth,several kinds of compound bioelectret materials of collagen/chitosan were developed Their TSDC(thermally stimulated depolarization current)spectra were analyzed,and the compound bioelectret collagen/chitosan whose t α and I α were 37℃ and 2×10 -9 A respectively at polarized state was selected The cell culture study showed that the compound bioelectret material could promote normal cell growth when singly negatively polarized,and could inhibit cancer cell growth when singly positively polarized It proves that the rational designation of compound bioelectret has a broad application for clinical medicine展开更多
The aim of this work is to study the effects of the electret property of natural biopolymers (such as collagen) on tissue repair. Type I collagen was prepared from pigskin,and polarized by using the TSDC (thermally st...The aim of this work is to study the effects of the electret property of natural biopolymers (such as collagen) on tissue repair. Type I collagen was prepared from pigskin,and polarized by using the TSDC (thermally stimulated depolarization current) technique. The polarized materials are used for cell culture. and then the cell growth curve is drawn. It was found that the polarized biomaterials accelerated cell differentiation. which indicates that they may be applied in the biomedical field.展开更多
To explore the behaviour of bioelectret film in mineralization and degradation in vitro, chitosan film was prepared and polarized in an electric field at room temperature. Polarized and unpolarized chitosan films were...To explore the behaviour of bioelectret film in mineralization and degradation in vitro, chitosan film was prepared and polarized in an electric field at room temperature. Polarized and unpolarized chitosan films were soaked in 1.5 × SBF （ simalated body fluid） .sohaions for 7, 14 and 28 d at 37℃. The negativelycharged surface of the bioelectret film promoted greater mineralization than did unpolarized chitosan. Apatite formarion on the surface of the films was identified by X- ray diffraction and scanning electron microscopy. Bioelectret films had a higher rate of degradation than unpolarized material in vitro （ pH 7.4, 37℃ ） in the presence of 1.5 mg/mL lysozyme aver 7 d. The electret effect facilitated the degradation of the film. After 14 d, the degradation rates of the two kinds of film were the same.展开更多
文摘To explore the influence of compound bioelectret material′s dielectric property on the cell growth,several kinds of compound bioelectret materials of collagen/chitosan were developed Their TSDC(thermally stimulated depolarization current)spectra were analyzed,and the compound bioelectret collagen/chitosan whose t α and I α were 37℃ and 2×10 -9 A respectively at polarized state was selected The cell culture study showed that the compound bioelectret material could promote normal cell growth when singly negatively polarized,and could inhibit cancer cell growth when singly positively polarized It proves that the rational designation of compound bioelectret has a broad application for clinical medicine
文摘The aim of this work is to study the effects of the electret property of natural biopolymers (such as collagen) on tissue repair. Type I collagen was prepared from pigskin,and polarized by using the TSDC (thermally stimulated depolarization current) technique. The polarized materials are used for cell culture. and then the cell growth curve is drawn. It was found that the polarized biomaterials accelerated cell differentiation. which indicates that they may be applied in the biomedical field.
文摘To explore the behaviour of bioelectret film in mineralization and degradation in vitro, chitosan film was prepared and polarized in an electric field at room temperature. Polarized and unpolarized chitosan films were soaked in 1.5 × SBF （ simalated body fluid） .sohaions for 7, 14 and 28 d at 37℃. The negativelycharged surface of the bioelectret film promoted greater mineralization than did unpolarized chitosan. Apatite formarion on the surface of the films was identified by X- ray diffraction and scanning electron microscopy. Bioelectret films had a higher rate of degradation than unpolarized material in vitro （ pH 7.4, 37℃ ） in the presence of 1.5 mg/mL lysozyme aver 7 d. The electret effect facilitated the degradation of the film. After 14 d, the degradation rates of the two kinds of film were the same.
