Antibiotic resistance is one of the major issues in the medical field and a potential threat to human health.However,newly emerging antimicrobial compounds failed to combat antimicrobial resistance developed by bacter...Antibiotic resistance is one of the major issues in the medical field and a potential threat to human health.However,newly emerging antimicrobial compounds failed to combat antimicrobial resistance developed by bacterial pathogens.Recently,a bismuth-based complex has been developed to eradicate antimicrobial-resistant microorganism infections.The complex is known as organobismuth(III)phosphinate,which is said to be a potential broad-spectrum antimicrobial agent.This complex has been incorporated into the nanocellulose suspension to fabricate a biomedical composite for various applications.The composite can be fabricated by two methods namely vacuum filtration and spray coating.In this paper,the surface and topography of the composite are investigated and discussed in terms of SEM micrographs and their antimicrobial potential.This review focuses on the organo-bismuth nanocellulose composite and its biomedical application in the future.展开更多
Under hydrothermal conditions,isonicotinic acid reacted with BiCl 3 to give 1D zigzag chain complex [(C 6 H 6 NO 2) 2 ·(BiCl 5)·2H 2 O] n (1).Single-crystal X-ray determination shows that compound 1 cr...Under hydrothermal conditions,isonicotinic acid reacted with BiCl 3 to give 1D zigzag chain complex [(C 6 H 6 NO 2) 2 ·(BiCl 5)·2H 2 O] n (1).Single-crystal X-ray determination shows that compound 1 crystal-lizes in the monoclinic system,space group C2/c with a=13.115(3),b=19.957(4),c=7.9374(16),β=97.45(3)°,Z=4,V=2060.0(8) 3,C 12 H 16 BiCl 5 N 2 O 6,D c=2.162 g/cm 3,M r=670.50,λ(MoKa)=0.71073,μ=9.237 mm-1,F(000)=1272,R=0.0208 and wR=0.0503.Dielectric constant of compound 1 was measured at different conditions.Measurements on the dielectric properties of 1 showed that the 1D chain coordination polymer exhibited a dipolar chain relaxation process and a relatively high dielectric constant.展开更多
The mixed-quadriligand bismuth complex [Bi(S2CNEt2)2(NO3)]?[1,10-Phen] has been synthesized, and its crystal structure was determined by X-ray single-crystal diffraction. The crystal belongs to monoclinic, space gro...The mixed-quadriligand bismuth complex [Bi(S2CNEt2)2(NO3)]?[1,10-Phen] has been synthesized, and its crystal structure was determined by X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 10.074(17), b = 15.05(2), c = 18.99(3) ?, β = 98.85(3)o, V = 2845(8) ?3, Z = 4, F(000) = 1464, Dc = 1.746 g/cm3, μ = 6.523 mm-1, R = 0.0333 and wR = 0.0703. In this complex, the bismuth atom is eight-coordinated in a capped distorted pentagonal bipyramidal geometry.展开更多
The surface pressure-area (pi -A) isotherm of Schiff base aluminium (III), tris (2-hydroxy-5-nitro-N-dodecyl-benzylideneaminato) aluminium (III) (denoted as Al(TAl2)(3)), on pure water subphase was investigated. The m...The surface pressure-area (pi -A) isotherm of Schiff base aluminium (III), tris (2-hydroxy-5-nitro-N-dodecyl-benzylideneaminato) aluminium (III) (denoted as Al(TAl2)(3)), on pure water subphase was investigated. The molecular area, 0.48 nm(2), is one-third of expected value that indicated the aggregation took place. The Langmuir-Blodgett (LB) films of Al(TAl2), was transferred and characterized. The AFM image confirmed the formation of aggregates.展开更多
Two novel complexes, [Bi(III)(S2CNBn Et)3] 1 and [Bi(III)(S2CNPPPy-2)3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The stru...Two novel complexes, [Bi(III)(S2CNBn Et)3] 1 and [Bi(III)(S2CNPPPy-2)3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The structure reveals that complex 1 belongs to the monoclinic system, space group P21/c with a = 11.457(5), b = 17.437(8), c = 33.439(14), β= 98.499(8)o, Z = 4, V = 6607(5)3, Dc = 1.689 g·cm^-3, F(000) = 3328, μ= 5.742 mm^-1, the final R = 0.0906, w R = 0.1678 and S = 1.032. The structure indicates that complex 2 belongs to the triclinic system, space group P1 with a = 12.608(9), b = 12.622(8), c = 12.49(6), α = 102.652(15), β = 103.013(14), γ = 109.698(10)o, Z = 1, V = 1762.3(19)3, Dc = 1.741 g·cm^-3, F(000) = 916, μ = 5.395 mm^-1, the final R = 0.048 2, w R = 0.1206 and S =1.046. In the two complexes, each six-coordinated Bi(III) atom adopts a pentagonal pyramidal configuration with six sulfur atoms from three ligands, and the dimmer structures are formed by weak interactions of Bi···S between two molecules. The anticancer activities of the two complexes were studied by evaluating their cytotoxicities against several human cancer cell lines using the MTT assay. Results indicated complex 2 showed moderate cytotoxic effects on the selected cancer cells.展开更多
A novel dimer of the bismuth(Ⅲ) complex with dithiotetrahydropyrrolocarbamate, [Bi(S_2CNC_4H_8)_2·(NO_3)]_2, was synthesized and the crystal structure was determined by X-ray single crystal diffraction. The crys...A novel dimer of the bismuth(Ⅲ) complex with dithiotetrahydropyrrolocarbamate, [Bi(S_2CNC_4H_8)_2·(NO_3)]_2, was synthesized and the crystal structure was determined by X-ray single crystal diffraction. The crystal belongs to a monoclinic system with space group P2_1/n, a=0.64718(13) nm, b=2.6738(6) nm, c=1.0423(2) nm, β=106.384(3)°, Z=4, V=1.730(3) nm^3, D_c=2.163 g/cm^3, μ=10.682 mm^(-1), F(000)=1072, R=0.0329, wR=0.0659. The structure shows a distorted pentagonal bipyramidal configuration with the seven-coordinated central Bi atom. In the crystal, the molecular packing in the unit cell reveals that the two adjacent molecules are symmetrically linked each other in the dimer by virtue of a couple of Bi-S interaction.展开更多
A new complex, {Bi(Ⅲ)[S2CN(CH2C6H5)2]3}2·2CH3CN, was synthesized and characterized by elemental analysis, IR, TG, 1H NMR and X-ray single-crystal diffraction. The complex crystallizes in the triclinic system, sp...A new complex, {Bi(Ⅲ)[S2CN(CH2C6H5)2]3}2·2CH3CN, was synthesized and characterized by elemental analysis, IR, TG, 1H NMR and X-ray single-crystal diffraction. The complex crystallizes in the triclinic system, space group P1, with a = 12.705(6), b = 13.430(6), c = 15.489(12) , α = 102.135(12), β = 99.649(12), γ = 111.521(9)°, Z = 1, V = 2315(2) A3, Dc = 1.531 g·cm-3, F(000) = 1068, μ = 4.116 mm-1, the final R = 0.0559, w R = 0.1069 and S =1.056. The coordinated geometry of Bi(Ⅲ) with six sulfur atoms from three ligands is a distorted pentagonal pyramidal configuration, and the structural system is formed by weak interactions of Bi···S between two molecules. The complex was valued for its antibacterial activity by agar-streak method. It was found that the complex is weakly active against three of the five tested bacterial organisms.展开更多
A bismuth(Ⅲ) complex 1 (H2-4,4'-bipy)[Bi(HPPA)5](H2PPA).4H2O (H2PPA = p- hydroxy- phenylacetic acid, 4,4'-bipy = 4,4"-bipyridyl) was hydrothermally synthesized from p-hydroxy-phenylacetic acid (H2PPA),...A bismuth(Ⅲ) complex 1 (H2-4,4'-bipy)[Bi(HPPA)5](H2PPA).4H2O (H2PPA = p- hydroxy- phenylacetic acid, 4,4'-bipy = 4,4"-bipyridyl) was hydrothermally synthesized from p-hydroxy-phenylacetic acid (H2PPA), Bi(NO3)3"6H20 and 4,4'-bipyridyl, and characterized by elemental analysis, IR, molar conductivity and TG. The single-crystal X-ray diffraction studies demonstrated that the complex is of monoclinic system, space group P21 with a = 10.928(7), b = 22.558(7), c = 11.313(7) A, β = 91.864(4)°, V = 2787.7(4) A3, Z = 2, C58H61BiN2O22, Mr = 1347.07, F(000) = 1364, Dc= 1.605 g/cm-3, p(MoKa) = 3.247 mm-1, the final R = 0.0269 and wR = 0.0540 for 9776 observed reflections with I 〉 2or(I). The bismuth(I/I) is seven-coordinated with O atoms, forming a monocapped octahedral geometry. Complex 1 further forms a 3D supramolecular architecture by hydrogen bonds and π-π stacking interactions. Moreover, the interaction between the complex and DNA was studied by EtBr fluoescent probe.展开更多
The photocatalytic degradation on the bismuth containing complex oxide was revised in detail including the synthesis and classification of photocatalyts, and then the photocatalytic reaction, scavenger, and the mechan...The photocatalytic degradation on the bismuth containing complex oxide was revised in detail including the synthesis and classification of photocatalyts, and then the photocatalytic reaction, scavenger, and the mechanism of reaction. In particular, the perspectives of photocatalytic degradation on the bismuth containing oxide were analyzed in detail.展开更多
Recent years,many novel complexes have been prepared by using hetero-bidentate ligands.However,complexes with such ligands as 4-vinylpyridine which has two different coordinating sites have not been reported,and only ...Recent years,many novel complexes have been prepared by using hetero-bidentate ligands.However,complexes with such ligands as 4-vinylpyridine which has two different coordinating sites have not been reported,and only a few complexes of Cu(I)have been published^(1-3).The title complex Cu_2(C_5H_4N·CH=CH_2)_3Cl was prepared and characterized by elemental analyses,ICP,IR,and electronic spectra.Its conductivity,oxidation potential and reduction potential were measured.展开更多
The synthesis is and crystal structure are reported for the sheet-like compourd [CU2(oxpn)Fe(CN )5(NO)]. there oxpn is the dianion of M, M'-bis(3-aminopropyl)oxamide. This compound crustallizes in the orthogonal s...The synthesis is and crystal structure are reported for the sheet-like compourd [CU2(oxpn)Fe(CN )5(NO)]. there oxpn is the dianion of M, M'-bis(3-aminopropyl)oxamide. This compound crustallizes in the orthogonal space group Puma. with a=11 .413(4), b=22.242(5), c=7.736(2) A, and Z=4.The structure was refined to conventionat discrepancy factors R=0.047 and Pw=0.054. The Cu(II ) and Fe(III)centers are bridged by oxpn and cyanide, the formal behaves as a his-terdentate tigand bound to cooper(II)ion to form (II) dimers. whereas the latter bridges Cu(II) and Fe(III) centers in both symmetric and asymetric end- to-end bis-monodentate fashions, spreading out along be plane to form a 20 network. The Structure is made up of CuFe unit with Cu(II) and Fe(III) ions locating in a distorted square-based pyramid and a compressed octahedron, respectively.展开更多
It has previously been demonstrated that phenanthroline-based ligands used to make gold metallotherapuetics have the ability to exhibit cytotoxicity when not coordinated to the metal center. In an effort to help asses...It has previously been demonstrated that phenanthroline-based ligands used to make gold metallotherapuetics have the ability to exhibit cytotoxicity when not coordinated to the metal center. In an effort to help assess the mechanism by which these ligands may cause tumor cell death, iron binding and removal experiments have been considered. The close linkage between cell proliferation and intracellular iron concentrations suggest that iron deprivation strategies may be a mechanism involved in inhibiting tumor cell growth. With the creation of iron (III) phen complexes, the iron binding abilities of three polypyridal ligands [1,10-phenanthroline (phen), 2,9-dimethyl-1, 10-phenanthroline (methylphen), and 2,9-di-sec-butyl-1, 10-phenanthroline (sec-butylphen)] can be tested via a competition reaction with a known iron chelator. Therefore, iron (III) complexes possessing all three ligands were synthesized. Initial mass spectrometric and infrared absorption data indicate that iron (III) tetrachloride complex ions with protonated phen ligands (RphenH+) were formed: [phenH][FeCl4], [methylphenH][FeCl4], [sec-butylphenH][FeCl4]. UV-vis spectroscopy was used to monitor the stability of the complex ions, and it was found that the sec-butylpheniron complex was more stable than the phen and methylphen analogues. This was based on the observation that free ligand was observed immediately upon the addition of EDTA to the [phenH][FeCl4] and [methylphenH] [FeCl4] complex ions.展开更多
The kinetics of the periodate oxidation of chromium(III)-complex, [CrIII(NTA)(Ala)(H2O)]-(NTA = Nitrilotriacetate and Ala = ß-alanine) to Cr(VI) have been carried out for the temperature range 15°C - 35&...The kinetics of the periodate oxidation of chromium(III)-complex, [CrIII(NTA)(Ala)(H2O)]-(NTA = Nitrilotriacetate and Ala = ß-alanine) to Cr(VI) have been carried out for the temperature range 15°C - 35°C under pseudo-first order conditions, >>?[complex]. Reaction obeyed first order dependence with respect to and [Cr(III)], and the rate of reaction increases with increasing of pH for the range 3.40 - 4.45. Experimentally, the mechanism of this reaction is found to be consistent with the rate law in which the hydroxo species, [CrIII(NTA)(Ala)(OH)]2- is considerably much more reactive than their conjugate acid. ΔH* and ΔS* have been calculated. It is proposed that electron transfer occurs through an inner-sphere mechanism via coordination of to chromium(III).展开更多
Three new heterotrinuclear complexes have been synthesized and characterized, namely {[Gd(L)(2)](2)[Cu(pbaOH)]}(ClO4)(4), where pbaOH denotes 2-hydroxy-1,3-propylenebis(oxamato), L stands for 1,10-phenanthroline (phen...Three new heterotrinuclear complexes have been synthesized and characterized, namely {[Gd(L)(2)](2)[Cu(pbaOH)]}(ClO4)(4), where pbaOH denotes 2-hydroxy-1,3-propylenebis(oxamato), L stands for 1,10-phenanthroline (phen), 5-nitro-1,10-phenanthroline (NO2-phen) or 2,2'-bipyridyl (bpy). The temperature dependence of the magnetic susceptibility of ([Gd(phen)(2)(ClO4)](2)[Cu(pbaOH)])(ClO4)(2) has been studied in the 4-300K range, giving the exchange integral J = 6.69 cm(-1). This indicates a weak ferromagnetic interaction between the copper(II) and gadolinium(III) ions.展开更多
A comparative thermal decomposition kinetic investigation on Fe(III) complexes of a antipyrine Schiff base ligand, 1,2-Bis(imino-4’-antipyrinyl)ethane (GA)), with varying counter anions viz. CIO4-, NO3-, SCN-, Cl-, a...A comparative thermal decomposition kinetic investigation on Fe(III) complexes of a antipyrine Schiff base ligand, 1,2-Bis(imino-4’-antipyrinyl)ethane (GA)), with varying counter anions viz. CIO4-, NO3-, SCN-, Cl-, and Br-, has been done by thermogravimetric analysis by using Coats-Redfern equation. The kinetic parameters like activation energy (E), pre-exponential factor (A) and entropy of activation (ΔS) were quantified. On comparing the various kinetic parameters, lower activation energy was observed in second stage as compared to first thermal decomposition stage. The same trend has been observed for pre-exponential factor (A) and entropy of activation (ΔS). The present results show that the starting materials having higher activation energy (E), are more stable than the intermediate products, however;the intermediate products possess well-ordered chemical structure due to their highly negative entropy of activation (ΔS) values. The present investigation proves that the counter anions play an important role on the thermal decomposition kinetics of the complexes.展开更多
Spectrophotometric method was used to evaluate the kinetic of the complex formation from the reaction between H[Ru(III)Cl2(H2EDTA)] and the modifier agent [3-(2-aminoethyl)aminopropyl] trimethoxysilane (AEATS) (μ = 0...Spectrophotometric method was used to evaluate the kinetic of the complex formation from the reaction between H[Ru(III)Cl2(H2EDTA)] and the modifier agent [3-(2-aminoethyl)aminopropyl] trimethoxysilane (AEATS) (μ = 0.50 mol.dm-3 with NaCF3COO, 298.15 K), in pseudo-first order conditions. These studies showed that the reactions are successives producing several species influenced by the concentrations ratio. The electronics spectrum of all solutions showed a band in 457 nm with variable molar absorptivity (ε).展开更多
In this paper, a new thin-layer ion-exchange resin phase analytical method is introduced. It is based on that, the bismuthous cation can associate with iodic anions, so as to formed an anion complex [BiI4-] in a stron...In this paper, a new thin-layer ion-exchange resin phase analytical method is introduced. It is based on that, the bismuthous cation can associate with iodic anions, so as to formed an anion complex [BiI4-] in a strong acidic environments. This anion complex can also exchanges with a weaker anions on the surface active site of anion exchange resin, so that a [R+] [BiI4-] solid phase binary associational system is produced. Owing to the solid system is a great many dispersive particulates, it can be pressed to a thin-layer by press tools of the so called 搕hin-layer resin phase?or 搑esin phase? and using this solid association system spectrophotometry for the determination of trace metals. So it can increase the analytical sensitivity. This association system exhibits maximum absorbance at 460nm, and obeys Beer抯 law over the concentration range 0.01ug/ml^1.20ug/ml of bismuthous(III). It has a molar absorptivity of 7.1×105 [L/mol穋m]. It indicated the resin phase spectrophotometry is a sensitive analytical method for trace bismuthous. It is 18 times higher than routine aqueous spectrophotometry. The relative standard deviations is 1.82% (n=6) for the measurements of 0.5ug/ml Bi(III). The detection limit of Bismuthous(III) is 1.4×10-8mol/L. The method has applied to the analysis Bi(III) in environmental water samples.展开更多
Objective We previously reported that mutations in inner mitochondrial membrane peptidase 2-like(Immp2l)increase infarct volume,enhance superoxide production,and suppress mitochondrial respiration after transient cere...Objective We previously reported that mutations in inner mitochondrial membrane peptidase 2-like(Immp2l)increase infarct volume,enhance superoxide production,and suppress mitochondrial respiration after transient cerebral focal ischemia and reperfusion injury.The present study investigated the impact of heterozygous Immp2l mutation on mitochondria function after ischemia and reperfusion injury in mice.Methods Mice were subjected to middle cerebral artery occlusion for 1 h followed by 0,1,5,and 24 h of reperfusion.The effects of Immp2l^(+/−)on mitochondrial membrane potential,mitochondrial respiratory complex III activity,caspase-3,and apoptosis-inducing factor(AIF)translocation were examined.Results Immp2l^(+/−)increased ischemic brain damage and the number of TUNEL-positive cells compared with wild-type mice.Immp2l^(+/−)led to mitochondrial damage,mitochondrial membrane potential depolarization,mitochondrial respiratory complex III activity suppression,caspase-3 activation,and AIF nuclear translocation.Conclusion The adverse impact of Immp2l^(+/−)on the brain after ischemia and reperfusion might be related to mitochondrial damage that involves depolarization of the mitochondrial membrane potential,inhibition of the mitochondrial respiratory complex III,and activation of mitochondria-mediated cell death pathways.These results suggest that patients with stroke carrying Immp2l^(+/−)might have worse and more severe infarcts,followed by a worse prognosis than those without Immp2l mutations.展开更多
:In this paper we describe the molecular and crystal structures of the K3[Y(NTA)2(H2O)]· 6H2O(H3NTA=nitrilotriacetic acid). The crystal data are as follows: monoclinic system, C2/c space group, a=1.5268(3)nm,b=1...:In this paper we describe the molecular and crystal structures of the K3[Y(NTA)2(H2O)]· 6H2O(H3NTA=nitrilotriacetic acid). The crystal data are as follows: monoclinic system, C2/c space group, a=1.5268(3)nm,b=1.2833(3)nm,c=2.6079(5)nm,β =96.03(3)° ,V=5.0815(18)nm3,Z=8,M=708.68,Dc=1.852gcm-3,μ =2.875mm-1,F(000)=2880.The final R1 and wR2 are 0.0636 and 0.1523 for 4264 [I >2.0σ (I)] unique reflections and 0.1178 and 0.1651 for all 4364 reflections,respectively.In the title complex, the anion [Y(NTA)2(H2O)]3- has a nine-coordination structure with distorted monocapped square antiprism. Each group acts as a tetradentate ligand with three O atoms and one N atom and a H2O molecule caps a quadrilateral face as a ligand.It can be known that the Y(III) ion can form a high-coordinate compound with aminopolycarboxylic acid ligands because it has a larger ionic radius (0.104nm).展开更多
文摘Antibiotic resistance is one of the major issues in the medical field and a potential threat to human health.However,newly emerging antimicrobial compounds failed to combat antimicrobial resistance developed by bacterial pathogens.Recently,a bismuth-based complex has been developed to eradicate antimicrobial-resistant microorganism infections.The complex is known as organobismuth(III)phosphinate,which is said to be a potential broad-spectrum antimicrobial agent.This complex has been incorporated into the nanocellulose suspension to fabricate a biomedical composite for various applications.The composite can be fabricated by two methods namely vacuum filtration and spray coating.In this paper,the surface and topography of the composite are investigated and discussed in terms of SEM micrographs and their antimicrobial potential.This review focuses on the organo-bismuth nanocellulose composite and its biomedical application in the future.
基金supported by the Natural Science Foundation of Jiangsu Province (BK2008029)
文摘Under hydrothermal conditions,isonicotinic acid reacted with BiCl 3 to give 1D zigzag chain complex [(C 6 H 6 NO 2) 2 ·(BiCl 5)·2H 2 O] n (1).Single-crystal X-ray determination shows that compound 1 crystal-lizes in the monoclinic system,space group C2/c with a=13.115(3),b=19.957(4),c=7.9374(16),β=97.45(3)°,Z=4,V=2060.0(8) 3,C 12 H 16 BiCl 5 N 2 O 6,D c=2.162 g/cm 3,M r=670.50,λ(MoKa)=0.71073,μ=9.237 mm-1,F(000)=1272,R=0.0208 and wR=0.0503.Dielectric constant of compound 1 was measured at different conditions.Measurements on the dielectric properties of 1 showed that the 1D chain coordination polymer exhibited a dipolar chain relaxation process and a relatively high dielectric constant.
基金This project was supported by the National Natural Science Foundation of China (No. 20271025) and Natural Science Foundation of Shandong Province (No. L2003B01)
文摘The mixed-quadriligand bismuth complex [Bi(S2CNEt2)2(NO3)]?[1,10-Phen] has been synthesized, and its crystal structure was determined by X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 10.074(17), b = 15.05(2), c = 18.99(3) ?, β = 98.85(3)o, V = 2845(8) ?3, Z = 4, F(000) = 1464, Dc = 1.746 g/cm3, μ = 6.523 mm-1, R = 0.0333 and wR = 0.0703. In this complex, the bismuth atom is eight-coordinated in a capped distorted pentagonal bipyramidal geometry.
基金the NSFC (29973026, 29773017) and Beijing Natural Science Foundation (2992007) for the provision of financial support.
文摘The surface pressure-area (pi -A) isotherm of Schiff base aluminium (III), tris (2-hydroxy-5-nitro-N-dodecyl-benzylideneaminato) aluminium (III) (denoted as Al(TAl2)(3)), on pure water subphase was investigated. The molecular area, 0.48 nm(2), is one-third of expected value that indicated the aggregation took place. The Langmuir-Blodgett (LB) films of Al(TAl2), was transferred and characterized. The AFM image confirmed the formation of aggregates.
基金Supported by the International Cooperation Project of the Science&Technology Agency of Henan Province(No.134300510013)
文摘Two novel complexes, [Bi(III)(S2CNBn Et)3] 1 and [Bi(III)(S2CNPPPy-2)3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The structure reveals that complex 1 belongs to the monoclinic system, space group P21/c with a = 11.457(5), b = 17.437(8), c = 33.439(14), β= 98.499(8)o, Z = 4, V = 6607(5)3, Dc = 1.689 g·cm^-3, F(000) = 3328, μ= 5.742 mm^-1, the final R = 0.0906, w R = 0.1678 and S = 1.032. The structure indicates that complex 2 belongs to the triclinic system, space group P1 with a = 12.608(9), b = 12.622(8), c = 12.49(6), α = 102.652(15), β = 103.013(14), γ = 109.698(10)o, Z = 1, V = 1762.3(19)3, Dc = 1.741 g·cm^-3, F(000) = 916, μ = 5.395 mm^-1, the final R = 0.048 2, w R = 0.1206 and S =1.046. In the two complexes, each six-coordinated Bi(III) atom adopts a pentagonal pyramidal configuration with six sulfur atoms from three ligands, and the dimmer structures are formed by weak interactions of Bi···S between two molecules. The anticancer activities of the two complexes were studied by evaluating their cytotoxicities against several human cancer cell lines using the MTT assay. Results indicated complex 2 showed moderate cytotoxic effects on the selected cancer cells.
基金Supported by the Natural Science Foundation of Shandong Province(No.L2 0 0 3B0 1) and the State Key L aboratory ofCrystal MaterialsShandong Universit
文摘A novel dimer of the bismuth(Ⅲ) complex with dithiotetrahydropyrrolocarbamate, [Bi(S_2CNC_4H_8)_2·(NO_3)]_2, was synthesized and the crystal structure was determined by X-ray single crystal diffraction. The crystal belongs to a monoclinic system with space group P2_1/n, a=0.64718(13) nm, b=2.6738(6) nm, c=1.0423(2) nm, β=106.384(3)°, Z=4, V=1.730(3) nm^3, D_c=2.163 g/cm^3, μ=10.682 mm^(-1), F(000)=1072, R=0.0329, wR=0.0659. The structure shows a distorted pentagonal bipyramidal configuration with the seven-coordinated central Bi atom. In the crystal, the molecular packing in the unit cell reveals that the two adjacent molecules are symmetrically linked each other in the dimer by virtue of a couple of Bi-S interaction.
基金supported by International Cooperation Project of the Science&Technology Agency of Henan Province(No.134300510013)
文摘A new complex, {Bi(Ⅲ)[S2CN(CH2C6H5)2]3}2·2CH3CN, was synthesized and characterized by elemental analysis, IR, TG, 1H NMR and X-ray single-crystal diffraction. The complex crystallizes in the triclinic system, space group P1, with a = 12.705(6), b = 13.430(6), c = 15.489(12) , α = 102.135(12), β = 99.649(12), γ = 111.521(9)°, Z = 1, V = 2315(2) A3, Dc = 1.531 g·cm-3, F(000) = 1068, μ = 4.116 mm-1, the final R = 0.0559, w R = 0.1069 and S =1.056. The coordinated geometry of Bi(Ⅲ) with six sulfur atoms from three ligands is a distorted pentagonal pyramidal configuration, and the structural system is formed by weak interactions of Bi···S between two molecules. The complex was valued for its antibacterial activity by agar-streak method. It was found that the complex is weakly active against three of the five tested bacterial organisms.
基金supported by the Natural Science Foundation of Zhejiang Province(LY12B01003)
文摘A bismuth(Ⅲ) complex 1 (H2-4,4'-bipy)[Bi(HPPA)5](H2PPA).4H2O (H2PPA = p- hydroxy- phenylacetic acid, 4,4'-bipy = 4,4"-bipyridyl) was hydrothermally synthesized from p-hydroxy-phenylacetic acid (H2PPA), Bi(NO3)3"6H20 and 4,4'-bipyridyl, and characterized by elemental analysis, IR, molar conductivity and TG. The single-crystal X-ray diffraction studies demonstrated that the complex is of monoclinic system, space group P21 with a = 10.928(7), b = 22.558(7), c = 11.313(7) A, β = 91.864(4)°, V = 2787.7(4) A3, Z = 2, C58H61BiN2O22, Mr = 1347.07, F(000) = 1364, Dc= 1.605 g/cm-3, p(MoKa) = 3.247 mm-1, the final R = 0.0269 and wR = 0.0540 for 9776 observed reflections with I 〉 2or(I). The bismuth(I/I) is seven-coordinated with O atoms, forming a monocapped octahedral geometry. Complex 1 further forms a 3D supramolecular architecture by hydrogen bonds and π-π stacking interactions. Moreover, the interaction between the complex and DNA was studied by EtBr fluoescent probe.
基金Supported by the Self-raised Project for the Basic Research for Application of Yunnan Province(2013FZ109)the Follow-up Project of Qujing Normal University for the National Natural Science Foundation(2106512005)+1 种基金the Innovation and Entrepreneurship Project for College Students of Qujing Normal Universitythe Project for Innovation Team of the Applied Chemical Material Preparation of Qujing Normal University(2106531001)
文摘The photocatalytic degradation on the bismuth containing complex oxide was revised in detail including the synthesis and classification of photocatalyts, and then the photocatalytic reaction, scavenger, and the mechanism of reaction. In particular, the perspectives of photocatalytic degradation on the bismuth containing oxide were analyzed in detail.
文摘Recent years,many novel complexes have been prepared by using hetero-bidentate ligands.However,complexes with such ligands as 4-vinylpyridine which has two different coordinating sites have not been reported,and only a few complexes of Cu(I)have been published^(1-3).The title complex Cu_2(C_5H_4N·CH=CH_2)_3Cl was prepared and characterized by elemental analyses,ICP,IR,and electronic spectra.Its conductivity,oxidation potential and reduction potential were measured.
文摘The synthesis is and crystal structure are reported for the sheet-like compourd [CU2(oxpn)Fe(CN )5(NO)]. there oxpn is the dianion of M, M'-bis(3-aminopropyl)oxamide. This compound crustallizes in the orthogonal space group Puma. with a=11 .413(4), b=22.242(5), c=7.736(2) A, and Z=4.The structure was refined to conventionat discrepancy factors R=0.047 and Pw=0.054. The Cu(II ) and Fe(III)centers are bridged by oxpn and cyanide, the formal behaves as a his-terdentate tigand bound to cooper(II)ion to form (II) dimers. whereas the latter bridges Cu(II) and Fe(III) centers in both symmetric and asymetric end- to-end bis-monodentate fashions, spreading out along be plane to form a 20 network. The Structure is made up of CuFe unit with Cu(II) and Fe(III) ions locating in a distorted square-based pyramid and a compressed octahedron, respectively.
文摘It has previously been demonstrated that phenanthroline-based ligands used to make gold metallotherapuetics have the ability to exhibit cytotoxicity when not coordinated to the metal center. In an effort to help assess the mechanism by which these ligands may cause tumor cell death, iron binding and removal experiments have been considered. The close linkage between cell proliferation and intracellular iron concentrations suggest that iron deprivation strategies may be a mechanism involved in inhibiting tumor cell growth. With the creation of iron (III) phen complexes, the iron binding abilities of three polypyridal ligands [1,10-phenanthroline (phen), 2,9-dimethyl-1, 10-phenanthroline (methylphen), and 2,9-di-sec-butyl-1, 10-phenanthroline (sec-butylphen)] can be tested via a competition reaction with a known iron chelator. Therefore, iron (III) complexes possessing all three ligands were synthesized. Initial mass spectrometric and infrared absorption data indicate that iron (III) tetrachloride complex ions with protonated phen ligands (RphenH+) were formed: [phenH][FeCl4], [methylphenH][FeCl4], [sec-butylphenH][FeCl4]. UV-vis spectroscopy was used to monitor the stability of the complex ions, and it was found that the sec-butylpheniron complex was more stable than the phen and methylphen analogues. This was based on the observation that free ligand was observed immediately upon the addition of EDTA to the [phenH][FeCl4] and [methylphenH] [FeCl4] complex ions.
文摘The kinetics of the periodate oxidation of chromium(III)-complex, [CrIII(NTA)(Ala)(H2O)]-(NTA = Nitrilotriacetate and Ala = ß-alanine) to Cr(VI) have been carried out for the temperature range 15°C - 35°C under pseudo-first order conditions, >>?[complex]. Reaction obeyed first order dependence with respect to and [Cr(III)], and the rate of reaction increases with increasing of pH for the range 3.40 - 4.45. Experimentally, the mechanism of this reaction is found to be consistent with the rate law in which the hydroxo species, [CrIII(NTA)(Ala)(OH)]2- is considerably much more reactive than their conjugate acid. ΔH* and ΔS* have been calculated. It is proposed that electron transfer occurs through an inner-sphere mechanism via coordination of to chromium(III).
文摘Three new heterotrinuclear complexes have been synthesized and characterized, namely {[Gd(L)(2)](2)[Cu(pbaOH)]}(ClO4)(4), where pbaOH denotes 2-hydroxy-1,3-propylenebis(oxamato), L stands for 1,10-phenanthroline (phen), 5-nitro-1,10-phenanthroline (NO2-phen) or 2,2'-bipyridyl (bpy). The temperature dependence of the magnetic susceptibility of ([Gd(phen)(2)(ClO4)](2)[Cu(pbaOH)])(ClO4)(2) has been studied in the 4-300K range, giving the exchange integral J = 6.69 cm(-1). This indicates a weak ferromagnetic interaction between the copper(II) and gadolinium(III) ions.
文摘A comparative thermal decomposition kinetic investigation on Fe(III) complexes of a antipyrine Schiff base ligand, 1,2-Bis(imino-4’-antipyrinyl)ethane (GA)), with varying counter anions viz. CIO4-, NO3-, SCN-, Cl-, and Br-, has been done by thermogravimetric analysis by using Coats-Redfern equation. The kinetic parameters like activation energy (E), pre-exponential factor (A) and entropy of activation (ΔS) were quantified. On comparing the various kinetic parameters, lower activation energy was observed in second stage as compared to first thermal decomposition stage. The same trend has been observed for pre-exponential factor (A) and entropy of activation (ΔS). The present results show that the starting materials having higher activation energy (E), are more stable than the intermediate products, however;the intermediate products possess well-ordered chemical structure due to their highly negative entropy of activation (ΔS) values. The present investigation proves that the counter anions play an important role on the thermal decomposition kinetics of the complexes.
文摘Spectrophotometric method was used to evaluate the kinetic of the complex formation from the reaction between H[Ru(III)Cl2(H2EDTA)] and the modifier agent [3-(2-aminoethyl)aminopropyl] trimethoxysilane (AEATS) (μ = 0.50 mol.dm-3 with NaCF3COO, 298.15 K), in pseudo-first order conditions. These studies showed that the reactions are successives producing several species influenced by the concentrations ratio. The electronics spectrum of all solutions showed a band in 457 nm with variable molar absorptivity (ε).
文摘In this paper, a new thin-layer ion-exchange resin phase analytical method is introduced. It is based on that, the bismuthous cation can associate with iodic anions, so as to formed an anion complex [BiI4-] in a strong acidic environments. This anion complex can also exchanges with a weaker anions on the surface active site of anion exchange resin, so that a [R+] [BiI4-] solid phase binary associational system is produced. Owing to the solid system is a great many dispersive particulates, it can be pressed to a thin-layer by press tools of the so called 搕hin-layer resin phase?or 搑esin phase? and using this solid association system spectrophotometry for the determination of trace metals. So it can increase the analytical sensitivity. This association system exhibits maximum absorbance at 460nm, and obeys Beer抯 law over the concentration range 0.01ug/ml^1.20ug/ml of bismuthous(III). It has a molar absorptivity of 7.1×105 [L/mol穋m]. It indicated the resin phase spectrophotometry is a sensitive analytical method for trace bismuthous. It is 18 times higher than routine aqueous spectrophotometry. The relative standard deviations is 1.82% (n=6) for the measurements of 0.5ug/ml Bi(III). The detection limit of Bismuthous(III) is 1.4×10-8mol/L. The method has applied to the analysis Bi(III) in environmental water samples.
基金This study was supported by the National Natural Science Foundation of China(Nos.81360196,81760240the Natural Science Foundation of Ningxia(No.2022AAC03159)the Ningxia Innovation Team of the Foundation and Clinical Research of Diabetes and Its Complications(No.NXKJT2019010).
文摘Objective We previously reported that mutations in inner mitochondrial membrane peptidase 2-like(Immp2l)increase infarct volume,enhance superoxide production,and suppress mitochondrial respiration after transient cerebral focal ischemia and reperfusion injury.The present study investigated the impact of heterozygous Immp2l mutation on mitochondria function after ischemia and reperfusion injury in mice.Methods Mice were subjected to middle cerebral artery occlusion for 1 h followed by 0,1,5,and 24 h of reperfusion.The effects of Immp2l^(+/−)on mitochondrial membrane potential,mitochondrial respiratory complex III activity,caspase-3,and apoptosis-inducing factor(AIF)translocation were examined.Results Immp2l^(+/−)increased ischemic brain damage and the number of TUNEL-positive cells compared with wild-type mice.Immp2l^(+/−)led to mitochondrial damage,mitochondrial membrane potential depolarization,mitochondrial respiratory complex III activity suppression,caspase-3 activation,and AIF nuclear translocation.Conclusion The adverse impact of Immp2l^(+/−)on the brain after ischemia and reperfusion might be related to mitochondrial damage that involves depolarization of the mitochondrial membrane potential,inhibition of the mitochondrial respiratory complex III,and activation of mitochondria-mediated cell death pathways.These results suggest that patients with stroke carrying Immp2l^(+/−)might have worse and more severe infarcts,followed by a worse prognosis than those without Immp2l mutations.
文摘:In this paper we describe the molecular and crystal structures of the K3[Y(NTA)2(H2O)]· 6H2O(H3NTA=nitrilotriacetic acid). The crystal data are as follows: monoclinic system, C2/c space group, a=1.5268(3)nm,b=1.2833(3)nm,c=2.6079(5)nm,β =96.03(3)° ,V=5.0815(18)nm3,Z=8,M=708.68,Dc=1.852gcm-3,μ =2.875mm-1,F(000)=2880.The final R1 and wR2 are 0.0636 and 0.1523 for 4264 [I >2.0σ (I)] unique reflections and 0.1178 and 0.1651 for all 4364 reflections,respectively.In the title complex, the anion [Y(NTA)2(H2O)]3- has a nine-coordination structure with distorted monocapped square antiprism. Each group acts as a tetradentate ligand with three O atoms and one N atom and a H2O molecule caps a quadrilateral face as a ligand.It can be known that the Y(III) ion can form a high-coordinate compound with aminopolycarboxylic acid ligands because it has a larger ionic radius (0.104nm).