A three-dimensional rigid body on the shape of a parallelepiped is modelled in order to rock on a side or a vertex of the base,in order to evaluate the seismic response of rigid blocks lying on a horizontal support.Th...A three-dimensional rigid body on the shape of a parallelepiped is modelled in order to rock on a side or a vertex of the base,in order to evaluate the seismic response of rigid blocks lying on a horizontal support.The center of mass of the body is considered as eccentric with respect to its geometric center.As seismic input,three Italian recorded accelerograms,with different spectral content,are used.The study is mainly conducted to highlight the differences between the seismic response of 2D and 3D models of rigid blocks,with the aim to understand if,in some cases,the use of the 3D model of rigid block is required to obtain safer results.In fact,the outcomes show that in some ranges of the geometrical and mechanical parameters that characterize the excitation and the body,a two-dimensional model,which is not able to consider the 3D rocking on a vertex,can provide unsafe results.In particular,it is found that the overturning process of the three-dimensional block can occur under excitations which are lower than those which overturn a corresponding two-dimensional block.展开更多
In this research, a method called ANNMG is presented to integrate Artificial Neural Networks and Geostatistics for optimum mineral reserve evaluation. The word ANNMG simply means Artificial Neural Network Model integr...In this research, a method called ANNMG is presented to integrate Artificial Neural Networks and Geostatistics for optimum mineral reserve evaluation. The word ANNMG simply means Artificial Neural Network Model integrated with Geostatiscs, In this procedure, the Artificial Neural Network was trained, tested and validated using assay values obtained from exploratory drillholes. Next, the validated model was used to generalize mineral grades at known and unknown sampled locations inside the drilling region respectively. Finally, the reproduced and generalized assay values were combined and fed to geostatistics in order to develop a geological 3D block model. The regression analysis revealed that the predicted sample grades were in close proximity to the actual sample grades, The generalized grades from the ANNMG show that this process could be used to complement exploration activities thereby reducing drilling requirement. It could also be an effective mineral reserve evaluation method that could oroduce optimum block model for mine design.展开更多
The San Rafael Block(SRB)is part of one of the main retroarc volcanic provinces in southern Central Andes in Mendoza,Argentina.This block is located in the Andean foothills between the orogenic front and foreland base...The San Rafael Block(SRB)is part of one of the main retroarc volcanic provinces in southern Central Andes in Mendoza,Argentina.This block is located in the Andean foothills between the orogenic front and foreland basement uplifts of late Miocene age.In order to analyze the geochronological evolution of the Quaternary volcanism in the region,several geologic and geophysical studies have been conducted.Nevertheless,the crust,where the SRB is located,has not been well characterized yet.Based on gravimetric and magnetic data,together with isostatic and elastic thickness analyses,we modeled the crustal structure of the area.Information obtained has allowed us to understand the crust where the SRB and the Payenia volcanic province are located.Bouguer anomalies indicate that the SRB presents higher densities to the North of Cerro Nevado and Moho calculations suggest depths for this block between 40 and 50 km.Determinations of elastic thickness would indicate that the crust supporting the San Rafael Block presents values of approximately 10 km,being enough to support the block loading.However,in the Payenia region,elastic thickness values are close to zero due to the regional temperature increase.展开更多
A sustained monaural block of auditory air-conduction model was established in rats through subcutaneous suture in the right ear canal.The gene expression levels of hypothalamic N-methyl-D-aspartate receptor NR1,NR2A,...A sustained monaural block of auditory air-conduction model was established in rats through subcutaneous suture in the right ear canal.The gene expression levels of hypothalamic N-methyl-D-aspartate receptor NR1,NR2A,NR2B and NR2C mRNA in the auditory central nervous system of Sprague-Dawley rats at postnatal 9,23,37 days were determined after an environmental change.Reverse transcription-PCR assay showed that the critical period for the development of NR1,NR2A,and NR2B subunits in the left hypothalamus and NR1-and NR2B-dependent auditory neurons in the right hypothalamus terminated 23 days after the suture in the right ear.The critical period for the development of NR2A subunit-dependent auditory neurons in the right hypothalamus was terminated by postnatal day 37.The results confirmed that N-methyl-D-aspartate receptor subunits in the hypothalamus may be regulated by the auditory environment.展开更多
The cross-metathesis degradation of poly(styrene-co-butadiene) (styrene, 30 wt%) (SB-1) and poly(styrene-co-butadiene) (styrene, 21 wt%) (SB- 2) in the presence of essential oils and d-limo-nene as chain transfer agen...The cross-metathesis degradation of poly(styrene-co-butadiene) (styrene, 30 wt%) (SB-1) and poly(styrene-co-butadiene) (styrene, 21 wt%) (SB- 2) in the presence of essential oils and d-limo-nene as chain transfer agents (CTAs) using Rualkylidene catalysts (PCy3)2(Cl)2Ru = CHPh (I) and (1,3-diphenyl-4,5-dihydroimidazol-2-ylidene) (PCy3)Cl2Ru=CHPh (II) was studied. Terpene-terminated butadiene oligomers and polystyrene blocks were obtained as products of the degradation of SB-1 and SB-2. Catalysts I and II showed high activity in the degradation of SB copolymers to produce the low molecular weight products (Mn = 276 - 335 g·mol-1) and yields ranging from 91% - 95%. The cross-metathesis degradation of copolymers in organic solvents and in citrus oils (mandarin, orange and lemon oils) proceeded with similar efficiency and resulted in the same molecular weight butadiene oligomers. According to GS/MS (EI) analysis, the main products of the degradation of SB-1 copolymer with d-limonene were limonene-terminated oligomers of series Am (m = 1 - 4).展开更多
To enhance the reverse blocking capability with low specific on-resistance,a novel vertical metal-oxidesemiconductor field-effect transistor(MOSFET) with a Schottky-drian(SD) and SD-connected semisuperjunctions(S...To enhance the reverse blocking capability with low specific on-resistance,a novel vertical metal-oxidesemiconductor field-effect transistor(MOSFET) with a Schottky-drian(SD) and SD-connected semisuperjunctions(SDD-semi-SJ),named as SD-D-semi-SJ MOSFET is proposed and demonstrated by two-dimensional(2D) numerical simulations.The SD contacted with the n-pillar exhibits the Schottky-contact property,and that with the p-pillar the Ohmic-contact property.Based on these features,the SD-D-semi-SJ MOSFET could obviously overcome the great obstacle of the ineffectivity of the conventional superjunctions(SJ) or semisuperjunctions(semi-SJ) for the reverse applications and achieve a satisfactory trade-off between the reverse breakdown voltage(BV) and the specific on-resistance(R_(on)A).For a given pillar width and n-drift thickness,there exists a proper range of n-drift concentration(N),in which the SD-D-semi-SJ MOSFET could exhibit a better trade-off of R_(on)A-BV compared to the predication of SJ MOSFET in the forward applications.And what is much valuable,in this proper range of N,the desired BV and good trade-off could be achieved only by determining the pillar thickness,with the top assist layer thickness unchanged.Detailed analyses have been carried out to get physical insights into the intrinsic mechanism of R_(on)A-BV improvement in SD-D-semi-SJ MOSFET.These results demonstrate a great potential of SD-D-semi-SJ MOSFET in reverse applications.展开更多
Methoxy poly(ethylene glycol)-poly(D,L-lactide) block copolymers (PEG-PLA) were prepared through ring-opening polymerization.The oil in water suspension method was used to prepare block copolymer micelles. The critica...Methoxy poly(ethylene glycol)-poly(D,L-lactide) block copolymers (PEG-PLA) were prepared through ring-opening polymerization.The oil in water suspension method was used to prepare block copolymer micelles. The critical micelle concentration (CMC) by fluorescence spectroscopy was 0.0056 mg·ml -1 . The physical state of the inner core region of micelles was characterized with 1HNMR. The size of indomethacin (IMC) loaded micelles measured by dynamic light scattering (DLS) showed narrow monodisperse size distribution and the average diameters were less than 50 nm. In addition, the nanoparticles with relatively high drug loading content (DLC) were obtained.展开更多
Two chiral building blocks 1 and 2 for anti-and syn-1, 3-diols has been achieved in 8 steps and 7 steps respectively, starting from the readily available and inexpensive D (+)-xylose 3.
Piloti is commonly used in tropical and subtropical climate zones to get high wind velocity and create shadowed areas in order to optimize the living environment of residential blocks,but there are few studies to reve...Piloti is commonly used in tropical and subtropical climate zones to get high wind velocity and create shadowed areas in order to optimize the living environment of residential blocks,but there are few studies to reveal the influence of piloti on the radiant environment of residential blocks systematically. Taking the city of Guangzhou as an example,using 3-D Unsteady State Heat Balance Radiation Calculation Method,this paper shows that the mean radiant temperature( MRT) under piloti area increases with the increase of piloti ratio,and especially when piloti ratio is equal to 100%,the MRT increase trend becomes sharp. The MRT of exposed area decreases with the increase of piloti ratio,especially when piloti ratio reaches 100%,the decrease trend of MRT becomes sharp,which offers the reference for the study on piloti design in subtropical climate zones and further research on living environment by CFD simulation in residential blocks.展开更多
基金partially funded by FY 2009-2010 PRIN–Italian Ministry for Research
文摘A three-dimensional rigid body on the shape of a parallelepiped is modelled in order to rock on a side or a vertex of the base,in order to evaluate the seismic response of rigid blocks lying on a horizontal support.The center of mass of the body is considered as eccentric with respect to its geometric center.As seismic input,three Italian recorded accelerograms,with different spectral content,are used.The study is mainly conducted to highlight the differences between the seismic response of 2D and 3D models of rigid blocks,with the aim to understand if,in some cases,the use of the 3D model of rigid block is required to obtain safer results.In fact,the outcomes show that in some ranges of the geometrical and mechanical parameters that characterize the excitation and the body,a two-dimensional model,which is not able to consider the 3D rocking on a vertex,can provide unsafe results.In particular,it is found that the overturning process of the three-dimensional block can occur under excitations which are lower than those which overturn a corresponding two-dimensional block.
基金the management of Sierra Rutile Company for providing the drillhole dataset used in this studythe Japanese Ministry of Education Science and Technology (MEXT) Scholarship for academic funding
文摘In this research, a method called ANNMG is presented to integrate Artificial Neural Networks and Geostatistics for optimum mineral reserve evaluation. The word ANNMG simply means Artificial Neural Network Model integrated with Geostatiscs, In this procedure, the Artificial Neural Network was trained, tested and validated using assay values obtained from exploratory drillholes. Next, the validated model was used to generalize mineral grades at known and unknown sampled locations inside the drilling region respectively. Finally, the reproduced and generalized assay values were combined and fed to geostatistics in order to develop a geological 3D block model. The regression analysis revealed that the predicted sample grades were in close proximity to the actual sample grades, The generalized grades from the ANNMG show that this process could be used to complement exploration activities thereby reducing drilling requirement. It could also be an effective mineral reserve evaluation method that could oroduce optimum block model for mine design.
文摘The San Rafael Block(SRB)is part of one of the main retroarc volcanic provinces in southern Central Andes in Mendoza,Argentina.This block is located in the Andean foothills between the orogenic front and foreland basement uplifts of late Miocene age.In order to analyze the geochronological evolution of the Quaternary volcanism in the region,several geologic and geophysical studies have been conducted.Nevertheless,the crust,where the SRB is located,has not been well characterized yet.Based on gravimetric and magnetic data,together with isostatic and elastic thickness analyses,we modeled the crustal structure of the area.Information obtained has allowed us to understand the crust where the SRB and the Payenia volcanic province are located.Bouguer anomalies indicate that the SRB presents higher densities to the North of Cerro Nevado and Moho calculations suggest depths for this block between 40 and 50 km.Determinations of elastic thickness would indicate that the crust supporting the San Rafael Block presents values of approximately 10 km,being enough to support the block loading.However,in the Payenia region,elastic thickness values are close to zero due to the regional temperature increase.
文摘A sustained monaural block of auditory air-conduction model was established in rats through subcutaneous suture in the right ear canal.The gene expression levels of hypothalamic N-methyl-D-aspartate receptor NR1,NR2A,NR2B and NR2C mRNA in the auditory central nervous system of Sprague-Dawley rats at postnatal 9,23,37 days were determined after an environmental change.Reverse transcription-PCR assay showed that the critical period for the development of NR1,NR2A,and NR2B subunits in the left hypothalamus and NR1-and NR2B-dependent auditory neurons in the right hypothalamus terminated 23 days after the suture in the right ear.The critical period for the development of NR2A subunit-dependent auditory neurons in the right hypothalamus was terminated by postnatal day 37.The results confirmed that N-methyl-D-aspartate receptor subunits in the hypothalamus may be regulated by the auditory environment.
文摘The cross-metathesis degradation of poly(styrene-co-butadiene) (styrene, 30 wt%) (SB-1) and poly(styrene-co-butadiene) (styrene, 21 wt%) (SB- 2) in the presence of essential oils and d-limo-nene as chain transfer agents (CTAs) using Rualkylidene catalysts (PCy3)2(Cl)2Ru = CHPh (I) and (1,3-diphenyl-4,5-dihydroimidazol-2-ylidene) (PCy3)Cl2Ru=CHPh (II) was studied. Terpene-terminated butadiene oligomers and polystyrene blocks were obtained as products of the degradation of SB-1 and SB-2. Catalysts I and II showed high activity in the degradation of SB copolymers to produce the low molecular weight products (Mn = 276 - 335 g·mol-1) and yields ranging from 91% - 95%. The cross-metathesis degradation of copolymers in organic solvents and in citrus oils (mandarin, orange and lemon oils) proceeded with similar efficiency and resulted in the same molecular weight butadiene oligomers. According to GS/MS (EI) analysis, the main products of the degradation of SB-1 copolymer with d-limonene were limonene-terminated oligomers of series Am (m = 1 - 4).
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61574112,61334002,61306017,61474091,and 61574110)the Natural Science Basic Research Plan in Shaanxi Province of China(Grant No.605119425012)
文摘To enhance the reverse blocking capability with low specific on-resistance,a novel vertical metal-oxidesemiconductor field-effect transistor(MOSFET) with a Schottky-drian(SD) and SD-connected semisuperjunctions(SDD-semi-SJ),named as SD-D-semi-SJ MOSFET is proposed and demonstrated by two-dimensional(2D) numerical simulations.The SD contacted with the n-pillar exhibits the Schottky-contact property,and that with the p-pillar the Ohmic-contact property.Based on these features,the SD-D-semi-SJ MOSFET could obviously overcome the great obstacle of the ineffectivity of the conventional superjunctions(SJ) or semisuperjunctions(semi-SJ) for the reverse applications and achieve a satisfactory trade-off between the reverse breakdown voltage(BV) and the specific on-resistance(R_(on)A).For a given pillar width and n-drift thickness,there exists a proper range of n-drift concentration(N),in which the SD-D-semi-SJ MOSFET could exhibit a better trade-off of R_(on)A-BV compared to the predication of SJ MOSFET in the forward applications.And what is much valuable,in this proper range of N,the desired BV and good trade-off could be achieved only by determining the pillar thickness,with the top assist layer thickness unchanged.Detailed analyses have been carried out to get physical insights into the intrinsic mechanism of R_(on)A-BV improvement in SD-D-semi-SJ MOSFET.These results demonstrate a great potential of SD-D-semi-SJ MOSFET in reverse applications.
文摘Methoxy poly(ethylene glycol)-poly(D,L-lactide) block copolymers (PEG-PLA) were prepared through ring-opening polymerization.The oil in water suspension method was used to prepare block copolymer micelles. The critical micelle concentration (CMC) by fluorescence spectroscopy was 0.0056 mg·ml -1 . The physical state of the inner core region of micelles was characterized with 1HNMR. The size of indomethacin (IMC) loaded micelles measured by dynamic light scattering (DLS) showed narrow monodisperse size distribution and the average diameters were less than 50 nm. In addition, the nanoparticles with relatively high drug loading content (DLC) were obtained.
文摘Two chiral building blocks 1 and 2 for anti-and syn-1, 3-diols has been achieved in 8 steps and 7 steps respectively, starting from the readily available and inexpensive D (+)-xylose 3.
基金Sponsored by the Strategic Japanese-Chinese Cooperation Program (Grant No.2011DFA91210)the Fundamental Research Funds for the Central Universities (Grant No.HIT.NSRIF.2014075),the Fundamental Research Funds for the Central Universities (Grant No.HIT.KISTP.201419)the Natural Science Foundation of Heilongjiang Province (Grant No.E201316)
文摘Piloti is commonly used in tropical and subtropical climate zones to get high wind velocity and create shadowed areas in order to optimize the living environment of residential blocks,but there are few studies to reveal the influence of piloti on the radiant environment of residential blocks systematically. Taking the city of Guangzhou as an example,using 3-D Unsteady State Heat Balance Radiation Calculation Method,this paper shows that the mean radiant temperature( MRT) under piloti area increases with the increase of piloti ratio,and especially when piloti ratio is equal to 100%,the MRT increase trend becomes sharp. The MRT of exposed area decreases with the increase of piloti ratio,especially when piloti ratio reaches 100%,the decrease trend of MRT becomes sharp,which offers the reference for the study on piloti design in subtropical climate zones and further research on living environment by CFD simulation in residential blocks.