Background:Facing the increasing prevalence of gestational diabetes mellitus (GDM),this study aimed to evaluate the management of GDM and its association with adverse pregnancy outcomes.Methods:The data of 996 inp...Background:Facing the increasing prevalence of gestational diabetes mellitus (GDM),this study aimed to evaluate the management of GDM and its association with adverse pregnancy outcomes.Methods:The data of 996 inpatients with GDM who terminated pregnancies in our hospital from January 2011 to December 2015 were collected.Treatments during pregnancy and the last hospital admission before delivery were analyzed.Pregnancy outcomes of the GDM patients were compared with 996 nondiabetic subjects matched by delivery year and gestational age.The association between fasting plasma glucose (FPG) and adverse pregnancy outcomes was examined by logistic regression analyses.Results:The average prevalence of GDM over the 5 years was 4.4% (1330/30,191).Within the GDM patients,42.8% (426/996) received dietary intervention,whereas 19.1% (190/996) received insulin treatment.Adverse outcomes were more likely to occur in patients with unsatisfactory control of blood glucose such as respiratory distress syndrome (RDS,x2 =13.373,P < 0.01).Elevated FPG was identified as an independent risk factor for premature birth (odds ratio [OR] =1.460,P < 0.001),neonatal care unit admission (OR =1.284,P < 0.001),RDS (OR=1.322,P =0.001),and stillbirth (OR =1.427,P < 0.001).Conclusions:Management of GDM in the real world of clinical practice was unsatisfactory,which might have contributed to adverse pregnancy outcomes.展开更多
目的系统评价群组化孕期保健模式(GPC)对妊娠期糖尿病(GDM)孕妇血糖控制与妊娠结局的影响。方法计算机检索PubMed、Web of Science、Springer Link、中国知网(CNKI)、维普(VIP)与万方数据库等数据库中关于GPC对GDM孕妇血糖控制及妊娠结...目的系统评价群组化孕期保健模式(GPC)对妊娠期糖尿病(GDM)孕妇血糖控制与妊娠结局的影响。方法计算机检索PubMed、Web of Science、Springer Link、中国知网(CNKI)、维普(VIP)与万方数据库等数据库中关于GPC对GDM孕妇血糖控制及妊娠结局影响的随机对照试验(RCT),采用Rev Man 5.4.1软件对数据进行meta分析。检索时间为2013年1月1日-2023年1月1日。结果共纳入6篇文献。meta分析结果表明:干预组(GPC)孕妇空腹血糖[WMD=-0.41,95%CI(-0.49,-0.33),P<0.00001]、餐后2 h血糖[WMD=-0.58,95%CI(-0.77,-0.38),P<0.001]及妊娠不良结局{妊娠高血压综合征[OR=0.37,95%CI(0.14,0.96),P=0.04]、剖宫产[OR=0.46,95%CI(0.27,0.78),P=0.04]、巨大儿[OR=0.19,95%CI(0.09,0.41),P<0.001]、产后出血[OR=0.19,95%CI(0.06,0.57),P=0.003]发生情况均低于对照组(传统孕期保健模式),差异均有统计学意义(P<0.05)。结论GPC能有效控制GDM孕妇血糖,减少妊娠不良结局的发生。展开更多
目的探讨有氧运动联合营养干预对妊娠糖尿病(GDM)患者血糖血脂水平的影响。方法选取2022年1月至2023年1月宜春市妇幼保健院妇产科收治的66例GDM患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各33例。对照组采用常规门诊健...目的探讨有氧运动联合营养干预对妊娠糖尿病(GDM)患者血糖血脂水平的影响。方法选取2022年1月至2023年1月宜春市妇幼保健院妇产科收治的66例GDM患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各33例。对照组采用常规门诊健康教育,观察组采用有氧运动联合营养干预。比较两组的血糖、血脂水平、围生期并发症及不良妊娠结局。结果观察组干预后的空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)水平低于对照组,差异有统计学意义(P<0.05);观察组干预后的血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL)水平低于对照组,高密度脂蛋白(HDL)水平高于对照组,差异有统计学意义(P<0.05);观察组的围生期并发症总发生率低于对照组,差异有统计学意义(P<0.05);观察组的不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。结论对GDM患者实施有氧运动联合营养干预效果理想,能够降低GDM患者血糖及血脂水平,减少围生期并发症及不良妊娠结局的发生。展开更多
目的:探讨妊娠期糖尿病(GDM)患者给予结构性有氧运动联合膳食管理对血糖控制的影响。方法:选取2022年1—12月北京怀柔医院收治的GDM患者共计110例,以随机数字表法分成研究组(55例)与对照组(55例),对照组给予常规治疗,研究组在对照组基...目的:探讨妊娠期糖尿病(GDM)患者给予结构性有氧运动联合膳食管理对血糖控制的影响。方法:选取2022年1—12月北京怀柔医院收治的GDM患者共计110例,以随机数字表法分成研究组(55例)与对照组(55例),对照组给予常规治疗,研究组在对照组基础上给予结构性有氧运动联合膳食管理,比较两组血糖水平、体重、体重指数(BMI)、分娩方式、不良妊娠结局、不良新生儿结局。结果:两组干预后空腹血糖(FPG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)水平均较干预前降低,研究组均较对照组更低,差异均有统计学意义(P<0.05);两组产前体重、BMI均较孕前提高,但研究组均较对照组更低,差异均有统计学意义(P<0.05);研究组自然分娩率较对照组更高,剖宫产率更低,差异均有统计学意义(P<0.05);研究组不良妊娠结局发生率(7.27%)较对照组(21.82%)更低,差异有统计学意义(P<0.05);研究组不良新生儿结局发生率(3.64%)较对照组(16.36%)更低,差异有统计学意义(P<0.05)。结论:GDM患者给予结构性有氧运动联合膳食管理,能够调节血糖水平,控制患者体重、BMI,促进自然分娩,改善妊娠结局及新生儿结局。展开更多
文摘Background:Facing the increasing prevalence of gestational diabetes mellitus (GDM),this study aimed to evaluate the management of GDM and its association with adverse pregnancy outcomes.Methods:The data of 996 inpatients with GDM who terminated pregnancies in our hospital from January 2011 to December 2015 were collected.Treatments during pregnancy and the last hospital admission before delivery were analyzed.Pregnancy outcomes of the GDM patients were compared with 996 nondiabetic subjects matched by delivery year and gestational age.The association between fasting plasma glucose (FPG) and adverse pregnancy outcomes was examined by logistic regression analyses.Results:The average prevalence of GDM over the 5 years was 4.4% (1330/30,191).Within the GDM patients,42.8% (426/996) received dietary intervention,whereas 19.1% (190/996) received insulin treatment.Adverse outcomes were more likely to occur in patients with unsatisfactory control of blood glucose such as respiratory distress syndrome (RDS,x2 =13.373,P < 0.01).Elevated FPG was identified as an independent risk factor for premature birth (odds ratio [OR] =1.460,P < 0.001),neonatal care unit admission (OR =1.284,P < 0.001),RDS (OR=1.322,P =0.001),and stillbirth (OR =1.427,P < 0.001).Conclusions:Management of GDM in the real world of clinical practice was unsatisfactory,which might have contributed to adverse pregnancy outcomes.
文摘目的系统评价群组化孕期保健模式(GPC)对妊娠期糖尿病(GDM)孕妇血糖控制与妊娠结局的影响。方法计算机检索PubMed、Web of Science、Springer Link、中国知网(CNKI)、维普(VIP)与万方数据库等数据库中关于GPC对GDM孕妇血糖控制及妊娠结局影响的随机对照试验(RCT),采用Rev Man 5.4.1软件对数据进行meta分析。检索时间为2013年1月1日-2023年1月1日。结果共纳入6篇文献。meta分析结果表明:干预组(GPC)孕妇空腹血糖[WMD=-0.41,95%CI(-0.49,-0.33),P<0.00001]、餐后2 h血糖[WMD=-0.58,95%CI(-0.77,-0.38),P<0.001]及妊娠不良结局{妊娠高血压综合征[OR=0.37,95%CI(0.14,0.96),P=0.04]、剖宫产[OR=0.46,95%CI(0.27,0.78),P=0.04]、巨大儿[OR=0.19,95%CI(0.09,0.41),P<0.001]、产后出血[OR=0.19,95%CI(0.06,0.57),P=0.003]发生情况均低于对照组(传统孕期保健模式),差异均有统计学意义(P<0.05)。结论GPC能有效控制GDM孕妇血糖,减少妊娠不良结局的发生。
文摘目的探讨有氧运动联合营养干预对妊娠糖尿病(GDM)患者血糖血脂水平的影响。方法选取2022年1月至2023年1月宜春市妇幼保健院妇产科收治的66例GDM患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各33例。对照组采用常规门诊健康教育,观察组采用有氧运动联合营养干预。比较两组的血糖、血脂水平、围生期并发症及不良妊娠结局。结果观察组干预后的空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)水平低于对照组,差异有统计学意义(P<0.05);观察组干预后的血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL)水平低于对照组,高密度脂蛋白(HDL)水平高于对照组,差异有统计学意义(P<0.05);观察组的围生期并发症总发生率低于对照组,差异有统计学意义(P<0.05);观察组的不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。结论对GDM患者实施有氧运动联合营养干预效果理想,能够降低GDM患者血糖及血脂水平,减少围生期并发症及不良妊娠结局的发生。
文摘目的:探讨妊娠期糖尿病(GDM)患者给予结构性有氧运动联合膳食管理对血糖控制的影响。方法:选取2022年1—12月北京怀柔医院收治的GDM患者共计110例,以随机数字表法分成研究组(55例)与对照组(55例),对照组给予常规治疗,研究组在对照组基础上给予结构性有氧运动联合膳食管理,比较两组血糖水平、体重、体重指数(BMI)、分娩方式、不良妊娠结局、不良新生儿结局。结果:两组干预后空腹血糖(FPG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)水平均较干预前降低,研究组均较对照组更低,差异均有统计学意义(P<0.05);两组产前体重、BMI均较孕前提高,但研究组均较对照组更低,差异均有统计学意义(P<0.05);研究组自然分娩率较对照组更高,剖宫产率更低,差异均有统计学意义(P<0.05);研究组不良妊娠结局发生率(7.27%)较对照组(21.82%)更低,差异有统计学意义(P<0.05);研究组不良新生儿结局发生率(3.64%)较对照组(16.36%)更低,差异有统计学意义(P<0.05)。结论:GDM患者给予结构性有氧运动联合膳食管理,能够调节血糖水平,控制患者体重、BMI,促进自然分娩,改善妊娠结局及新生儿结局。