月白散促进肛瘘术后创面愈合临床对照研究

目的观察月白散治疗肛瘘术后创面愈合的临床疗效。方法将120例肛瘘手术患者随机分为治疗组与对照组,各60例,治疗组术后创面换药采用月白散外敷,对照组术后创面换药采用百科瑞纱布外敷。观察2组患者术后第7天、第14天创面面积、创面溢液、创面出血量、创面疼痛及创面愈合时间。结果 2组患者术后第7天、第14天创面面积、创面溢液、创面出血量、创面疼痛等方面治疗组优于对照组(P<0.05);2组患者创面愈合时间比较,治疗组短于对照组(P<0.05),差异有统计学意义。结论月白散应用于肛瘘术后创面愈合可减少术后创面溢液、出血,减轻术后创面疼痛,促进创面愈合。

浅谈中医外治对创伤修复的作用

传统医学中有“偎脓长肉”、“祛腐生肌”等外治理论。现代研究认为外用中药通过调节局部创面中的微环境而促进愈合。通过对外用中药促进创伤修复机制的研究,将加深对中医外治理论的理解,为中药外用制剂的发展打好基础。

Oseltamevir Helps Cure COVID 19, Corona Pandemic Carried by Global Abortion/Contraception, Global Blood/Necrotic Tissue Environmental Pollution;Guaranteed Corona Elimination by Implementing Many Childbirth per Family [Earth Bus Fare/Ticket];Contraception Reversal;Abolition of Global Contraception [One Child Policy, Small Family Norms], Abortion [Jumping off Cliff to Fly-Marred Science]<br/>—Retrospective Analysis

Over the past one year and three months, 150 out patients with COVID 19 have been treated with early initiation of Oseltamevir 75 mg × 2 [150 mg] twice daily, with azithromycin, cephalosporin [to give atypical bacterial cover, gram positive bacterial cover, respectively] enabling cure. Corona virus pandemic was enabled by global contraception/abortion [non evidence based non medical practice] with its blood/necrotic tissue environmental pollution-documented by rising environmental oestrogen/alpha feto protein/beta human chorionic gonadotropin. Global contraception abortion with its blood, necrotic tissue environmental pollution provides a rich environmental media for Corona virus-a fastidious organism to become pandemic, with recurrent mutations. Guaranteed elimination of this fastidious organism-corona virus [and other microbes like Ebola, Nipah…] by implementing many childbirths per mother [earth bus fare/ticket] as God ordained abolition of global contraception, abortion, one child policy/small family norms [jumping off cliff to fly-marred science] with its blood/necrotic tissue pollution, mandatory reversal of contraception. Steroids are deleterious in any viral infection, being immunosuppressants-secondary mucormycosis, other fungal [less virulent] infections can follow;corona virus itself can mutate, gain virulence, drug resistance;but prior contraception-destroying germ cells, prior abortion [destruction of tissue] in the victim host result in auto-immunity of corresponding gradations including fatal HLH [Hemophagocytic lymphohistiocytosis], cytokine storm, requiring immunomodulation with plasmapheresis, steroids, hydroxychloroquine without much avail. Vaccine is live attenuated virus administered to our tissue, to elicit antibody response to the future viral invasion;inhaled virus elicits autoimmunity of varied gradations, [including fatal HLH] in the victim host, secondary to prior abortions/contraception [varied destruction of tissue, germ cells in the victim host];similar significant autoimmunity can be invoked in vaccine administered to tissue. Earth Bus Fare/ticket, many child birth per family as God ordained [with no menstrual blood pollution of mothers] leads to ozone generation, with ensuing unfailing monsoon rains, self sustaining ecology, zooming global economy, which increased longevity of life of parents, strengthened Earth’s magnet, absolute strong security preventing unmanned air vehicle robbery, non nuclear robotic war [remote control operations]. Whereas global abortion/contraception [one child policy, small family norms] [jumping off cliff to fly-marred science] with its blood/necrotic tissue environmental pollution results in inevitable emergence, drug resistance, [mutations] virulence of microbes including corona virus, ebola, nipah … inevitable ecological disasters namely-ozone depletion, tsunamis, hail storms, flash floods, tornadoes, oil fire, forest fire, … to name a few;global recession;early demise of contracepted/aborted parents.

益气活血合去腐生肌法治疗老年褥疮的临床研究

目的探讨益气活血合去腐生肌法治疗老年褥疮的临床疗效指标。方法选取2019年5月至2021年4月来我院就医的80例褥疮患者,将患者随机平均分为两组,对照组按常规消毒方法,碘伏消毒疮面和周围皮肤清创,而后凡士林油纱、无菌敷料覆盖包扎。观察组在对照组基础上不用凡士林油纱,而是在褥疮处涂适量褥疮药膏,再用无菌敷料进行包扎,同时服用补阳还五汤。对治疗后7、15、30 d红斑面积及疗效等方面进行全面的观察与记录。结果治疗1个月后,对照组有效率为72.5%,明显低于观察组的95.0%,两组比较,差异有统计学意义(P=0.041<0.05),且观察组能显著缩小患者褥疮红斑面积。结论益气活血合去腐生肌法配合常规治疗方法治疗老年褥疮疗效显著,未见明显不良反应。

牛磺胆酸钠致大鼠急性出血坏死性胰腺炎早期胰腺血流的测定

作者以5％的牛磺胆酸钠(Na-Tc)注入大鼠胆胰导管内,引起急性出血坏死性胰腺炎,以注射生理盐水为实验对照组,测定血清脂肪酶和淀粉酶活性,结果注射Na-Tc后3小时此两酶的活性均显著升高,12小时最明显;用^(36)RbCl示踪法测定,显示胰腺血流量和胰组织灌流量于注射Na-Tc后1小时明显升高,并维持较高水平至12小时下降。这些结果提示:Na-Tc致大鼠急性出血坏死性胰腺炎早期胰腺血流量增加,为一般炎症充血反应。

糖尿病足坏死性软组织感染的危险因素评估

目的明确糖尿病足坏死性软组织感染(NSTI)的危险因素。方法回顾性分析2010年1月至2017年12月经北京大学第一医院糖尿病足防治中心收治的糖尿病足感染(DFI)患者的病历资料,按照糖尿病足国际工作组(IWGDF)指南对所有患者进行感染程度分级,根据是否存在NSTI分为NSTI组与非NSTI组,利用单因素分析和Logistic回归分析明确NSTI的危险因素,利用受试者工作特征曲线(ROC)确定危险因素的临界值。结果共141例DFI患者纳入本研究,IWGDF分级为轻度、中度、重度感染患者分别占14.9%、61.0%、24.1%。NSTI组31例,非NSTI组110例,DFI中NSTI的发生率为22.0%。单因素分析结果显示,NSTI组年龄更低,溃疡病程更短,重度感染比率、大截肢率更高,糖化血红蛋白、白细胞计数(WBC)、C-反应蛋白(CRP)水平更高,血红蛋白、血清白蛋白值更低(P<0.05)。Logistic回归分析结果显示,WBC、CRP是NSTI的危险因素(P<0.05),且临界值分别为12.00×10^(9)/L、100 mg/L。结论DFI患者合并NSTI不少见,应常规按IWGDF指南对DFI患者进行感染程度分级,对于重度感染或是WBC≥12.00×10^(9)/L、CRP≥100 mg/L的DFI患者,应及时评估创面情况,警惕NSTI可能。

中药外洗在痔疮术后康复中的应用

目的:探讨中药外洗应用于痔疮术后康复中的疗效。方法:将80例痔疮手术患者随机分为试验组和对照组。对照组仅给予一般传统治疗;试验组在专科护理的基础上加用中药外洗,治疗后比较两组临床疗效。结果:试验组显效:35例(87.5%),有效:4例(10.0%),无效:1例(2.5%),有效率为97.5%;对照组显效:15例(37.5%),有效:10例(25.0%),无效:15例(37.5%),有效率为62.5%。两组比较差异有统计学意义(P<0.05)。结论:痔疮术后配合中药外洗可以提高治疗效果。