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Study on animals' femur blood flow alteration under inadequate decompression with ^(133)Xe isotope washout method
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作者 Yu Shao-Ning Bao Bo-Rong (Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences, Shanghai 201800 )Tian Wu-Xun +2 位作者 Yun Chang-Quan Zhu Xiang-Qi Wang Jing-Ying and Cao Bao-Gen (Naval Medical Research Institute, Shanghai 200433) 《Nuclear Science and Techniques》 SCIE CAS CSCD 1998年第2期124-128,共5页
Animals’ regional femur blood (F) alteration was studied under an inadequate decompression by using the inhaled isotope 133Xe washout method. Results showed that the average F on left and right side of minipigs’ fem... Animals’ regional femur blood (F) alteration was studied under an inadequate decompression by using the inhaled isotope 133Xe washout method. Results showed that the average F on left and right side of minipigs’ femur decreased from 15.4±1.8 and 16 .9±2.0 ml/ (100 g.min) (before exposure) to 10±1.8 and 11.1±1.6 ml/(100mg.min) (after expposure for 1.5 h under the pressure of 0.5 MPa and then decompression to normal with the rate of 0.03~0.04MPa/min), respectively; the blood flow of hematopoietic marrow tissues (f1)on both sides also decreased from 19.3±2.0 and 22.1±1.9 ml/(100mg.min) to 13.9±1.4 and 13.8±1.0 ml/(100 mg.min). The exact same alteration also happened in the experiment on New Zealand rabbits. It indicates that inadequate decompression in hyperbaric exposure can give rise to decrease animals’ bone blood flow and insufficient bone blood supply serves as one of the reasons for causing decompressive osteonecrosis. 展开更多
关键词 133xe同位素 动物股骨血液流 减压
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同位素清除法研究不充分减压时小型猪股骨血流量的变化 被引量:3
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作者 田伍训 余绍宁 +3 位作者 云昌全 朱祥祺 王瑾瑛 曹保根 《生物医学工程学杂志》 EI CAS CSCD 北大核心 1997年第1期26-29,37,共5页
本文研究了小型猪在高气压暴露不充分减压后股骨局部血流量的变化.动物在0.5MPa高厌空气舱内暴露1.5h,以0.03~004MPa/min匀速减压.骨血流量用吸入133Xe同位素清除法测定。结果为:暴露前平均骨血流量(F),左右侧分别为15.4... 本文研究了小型猪在高气压暴露不充分减压后股骨局部血流量的变化.动物在0.5MPa高厌空气舱内暴露1.5h,以0.03~004MPa/min匀速减压.骨血流量用吸入133Xe同位素清除法测定。结果为:暴露前平均骨血流量(F),左右侧分别为15.4±1.8和16.9±2.0ml/100g.min,造血骨髓组织血流量(f1)是19.1±2.0和21.3±2.1ml/100g·min(n=7).不充分减压后,F值降至10.3±1.8和11.1±1.6ml/100g·min,f1值降至13.9±1.4和13.8±1.0ml/100g·min,明显低于暴露前值(P<0.05).本研究表明:高气压暴露不充分减压可引起小型猪骨血流量降低.提示,骨供血不足是诱发减压性骨坏死的病因之一. 展开更多
关键词 骨血流量 减压性骨坏死 133清除法
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