BACKGROUND Severe horizontal bone deficiency of the maxillary anterior region is considered a major challenge in reconstruction and successful implant placement.Various approaches have been developed to augment bone v...BACKGROUND Severe horizontal bone deficiency of the maxillary anterior region is considered a major challenge in reconstruction and successful implant placement.Various approaches have been developed to augment bone volume.Of these approaches,onlay bone graft,alveolar bone splitting,and guided bone regeneration have been suggested.CASE SUMMARY A 22-year-old female patient,with no previous medical history,presented to the Department of Oral Implantology,Wuhan University due to a missing right maxillary incisor.The X-ray results showed severe horizontal bone deficiency,with an available bone width of 3.1-4.0 mm.The two bone blocks sandwich technique was performed to augment the bone volume.After 6 months healing,X-ray results showed that the newly formed alveolar ridge dimension increased to 4.7-9.5 mm horizontally.Implant insertion surgery was performed and allceramic restorations were fabricated.The implant was stable at the 1-year followup visit after restoration,and the X-ray showed a stable bone level around the dental implant.The scores for the pink esthetic score and white esthetic score were 12 and 8,respectively,and the patient was satisfied with the esthetic outcome.CONCLUSION The two bone blocks sandwich technique may be an alternative treatment option in augmenting severe horizontal bone deficiency of the anterior maxilla.展开更多
目的评价3D打印白硅钙石(bredigite,BRT)骨支架材料在大鼠Onlay骨移植中的效果。方法通过3D打印技术制备骨BRT支架材料作为实验组,β⁃磷酸三钙(β⁃tricalcium phosphate,β⁃TCP)骨支架材料作为对照组,通过扫描电镜(scanning electron mi...目的评价3D打印白硅钙石(bredigite,BRT)骨支架材料在大鼠Onlay骨移植中的效果。方法通过3D打印技术制备骨BRT支架材料作为实验组,β⁃磷酸三钙(β⁃tricalcium phosphate,β⁃TCP)骨支架材料作为对照组,通过扫描电镜(scanning electron microscopy,SEM)、X射线衍射(X⁃ray diffraction,XRD)、力学测试和体外降解测试实验对其进行表征观察。建立SD大鼠颅骨Onlay骨移植的动物模型,根据移植物的不同,分为自体骨移植组(Auto组)、β⁃TCP组及BRT组。术后12周获取标本行大体观察、micro⁃CT扫描检测分析、组织学HE染色。结果SEM观察显示,BRT有规则的多孔结构,XRD衍射峰较为锐利。与β⁃TCP组(11.29±1.30)MPa相比,BRT支架材料(46.80±3.44)MPa具有更好的力学强度(P<0.001);在体外第35天时,BRT降解率为27.18%±1.41%,并且在降解过程中释放钙、镁、硅离子。micro⁃CT及组织学染色实验结果提示,Auto组有一定程度的骨吸收,β⁃TCP和BRT组均有一定新骨生成。micro⁃CT和组织学定量结果,BRT组新生骨组织占比分别为16.83%±2.11%和19.08%±2.17%,均高于β⁃TCP组(8.48%±1.85%,10.81%±1.33%)(P<0.05)。结论3D打印BRT骨支架材料促进Onlay骨移植中的骨再生。展开更多
目的:探讨膜引导骨组织再生(membrane guided bone regeneration,MGBR)技术中,生物胶原膜在上颌前牙区种植骨增量中的作用。方法:选取我院2008年1月至2009年12月间上前牙区唇腭向骨量不足种植病例55例,随机分为2组,29例使用MGBR,同期植...目的:探讨膜引导骨组织再生(membrane guided bone regeneration,MGBR)技术中,生物胶原膜在上颌前牙区种植骨增量中的作用。方法:选取我院2008年1月至2009年12月间上前牙区唇腭向骨量不足种植病例55例,随机分为2组,29例使用MGBR,同期植入种植体40颗(有膜组);另26例不应用MGBR,植入种植体40颗(无膜组),作为对照。观察2组患者种植前及修复前种植区牙槽骨的情况。用卡尺测量牙槽骨唇腭向厚度,用X线骨密度分析法评估平均密度的变化。采用X线片图像分析测量软件(Sidexis)和SPSS16.0软件包进行比较分析。结果:单因素分析显示,有膜组种植术前与永久修复前牙槽骨唇腭向的厚度及密度差别有统计学意义(P<0.05);种植术前与永久修复前,有膜组与无膜组牙槽骨唇腭向厚度及骨密度变化的差别有统计学意义(P<0.05)。结论:使用生物膜的患者,唇腭向骨厚度及密度的增加均优于未使用生物膜的患者。在上前牙区骨量不足患者的种植术中,可推荐使用MGBR技术。展开更多
文摘BACKGROUND Severe horizontal bone deficiency of the maxillary anterior region is considered a major challenge in reconstruction and successful implant placement.Various approaches have been developed to augment bone volume.Of these approaches,onlay bone graft,alveolar bone splitting,and guided bone regeneration have been suggested.CASE SUMMARY A 22-year-old female patient,with no previous medical history,presented to the Department of Oral Implantology,Wuhan University due to a missing right maxillary incisor.The X-ray results showed severe horizontal bone deficiency,with an available bone width of 3.1-4.0 mm.The two bone blocks sandwich technique was performed to augment the bone volume.After 6 months healing,X-ray results showed that the newly formed alveolar ridge dimension increased to 4.7-9.5 mm horizontally.Implant insertion surgery was performed and allceramic restorations were fabricated.The implant was stable at the 1-year followup visit after restoration,and the X-ray showed a stable bone level around the dental implant.The scores for the pink esthetic score and white esthetic score were 12 and 8,respectively,and the patient was satisfied with the esthetic outcome.CONCLUSION The two bone blocks sandwich technique may be an alternative treatment option in augmenting severe horizontal bone deficiency of the anterior maxilla.
文摘目的评价3D打印白硅钙石(bredigite,BRT)骨支架材料在大鼠Onlay骨移植中的效果。方法通过3D打印技术制备骨BRT支架材料作为实验组,β⁃磷酸三钙(β⁃tricalcium phosphate,β⁃TCP)骨支架材料作为对照组,通过扫描电镜(scanning electron microscopy,SEM)、X射线衍射(X⁃ray diffraction,XRD)、力学测试和体外降解测试实验对其进行表征观察。建立SD大鼠颅骨Onlay骨移植的动物模型,根据移植物的不同,分为自体骨移植组(Auto组)、β⁃TCP组及BRT组。术后12周获取标本行大体观察、micro⁃CT扫描检测分析、组织学HE染色。结果SEM观察显示,BRT有规则的多孔结构,XRD衍射峰较为锐利。与β⁃TCP组(11.29±1.30)MPa相比,BRT支架材料(46.80±3.44)MPa具有更好的力学强度(P<0.001);在体外第35天时,BRT降解率为27.18%±1.41%,并且在降解过程中释放钙、镁、硅离子。micro⁃CT及组织学染色实验结果提示,Auto组有一定程度的骨吸收,β⁃TCP和BRT组均有一定新骨生成。micro⁃CT和组织学定量结果,BRT组新生骨组织占比分别为16.83%±2.11%和19.08%±2.17%,均高于β⁃TCP组(8.48%±1.85%,10.81%±1.33%)(P<0.05)。结论3D打印BRT骨支架材料促进Onlay骨移植中的骨再生。
文摘目的:探讨膜引导骨组织再生(membrane guided bone regeneration,MGBR)技术中,生物胶原膜在上颌前牙区种植骨增量中的作用。方法:选取我院2008年1月至2009年12月间上前牙区唇腭向骨量不足种植病例55例,随机分为2组,29例使用MGBR,同期植入种植体40颗(有膜组);另26例不应用MGBR,植入种植体40颗(无膜组),作为对照。观察2组患者种植前及修复前种植区牙槽骨的情况。用卡尺测量牙槽骨唇腭向厚度,用X线骨密度分析法评估平均密度的变化。采用X线片图像分析测量软件(Sidexis)和SPSS16.0软件包进行比较分析。结果:单因素分析显示,有膜组种植术前与永久修复前牙槽骨唇腭向的厚度及密度差别有统计学意义(P<0.05);种植术前与永久修复前,有膜组与无膜组牙槽骨唇腭向厚度及骨密度变化的差别有统计学意义(P<0.05)。结论:使用生物膜的患者,唇腭向骨厚度及密度的增加均优于未使用生物膜的患者。在上前牙区骨量不足患者的种植术中,可推荐使用MGBR技术。
