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Clinical Effectiveness of the Plate Screw Internal Fixation Technique in the Treatment of Patients with Traumatic Fractures of Long Bones in the Lower Extremities
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作者 Yong Cai 《Proceedings of Anticancer Research》 2024年第3期115-120,共6页
Objective: To investigate the effectiveness of the plate screw internal fixation technique on the clinical outcomes of patients with traumatic fractures of long bones in the lower extremities. Methods: From January 20... Objective: To investigate the effectiveness of the plate screw internal fixation technique on the clinical outcomes of patients with traumatic fractures of long bones in the lower extremities. Methods: From January 2022 to December 2023, 70 patients with traumatic fractures of long bones in the lower extremities were admitted to the hospital and randomly divided into two groups: the control group and the observation group, each consisting of 35 cases. The control group underwent traditional closed interlocking intramedullary nailing, while the observation group received internal fixation with steel plates and screws. Relevant surgical indicators, treatment effectiveness, and postoperative complication rates were compared between the two groups. Results: The observation group exhibited significantly short surgical duration (80.65 ± 5.01 vs. 88.36 ± 5.26 minutes), fracture healing time (13.27 ± 0.32 vs. 15.52 ± 0.48 weeks), and hospitalization days (10.49 ± 1.13 vs. 16.57 ± 1.15 days) compared to the control group (P = 0.000). The effective treatment rate was significantly higher in the observation group (29/82.86%) than in the control group (21/60.00%), with a significant difference observed (χ2 = 4.480, P = 0.034). Additionally, the complication rate in the observation group (2/5.71%) was significantly lower than that in the control group (8/22.86%), with a correlated difference (χ2 = 4.200, P = 0.040). Conclusion: The plate screw internal fixation technique demonstrates significant clinical efficacy in treating traumatic fractures of long bones in the lower extremities. It improves the healing rate, reduces complications, and represents a safe and effective treatment strategy worthy of widespread use and application. 展开更多
关键词 Plate screw internal fixation technique Traumatic fractures Long bones in the lower extremities EFFECTIVENESS
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Tackling bone loss of the lower extremity:vascularized bone grafting
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作者 Christine V.Schaeffer John T.Stranix 《Plastic and Aesthetic Research》 2022年第1期254-263,共10页
Post-traumatic lower extremity bone loss in the setting of high-energy trauma can occur acutely as a result of an open fracture and surgical debridement,or secondarily as a result of nonunion or infection.Several tech... Post-traumatic lower extremity bone loss in the setting of high-energy trauma can occur acutely as a result of an open fracture and surgical debridement,or secondarily as a result of nonunion or infection.Several techniques have been described in the literature for the management of these bony defects,including non-vascularized bone grafts,vascularized bone grafts and distraction osteogenesis.Herein,the authors review the role of vascularized bone grafts in the management of post-traumatic bone loss in the lower extremity. 展开更多
关键词 lower extremity vascularized bone segmental defect
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动态四点跪位训练对脊髓损伤患者髋关节骨密度及下肢运动功能的影响
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作者 王雪 许光旭 +1 位作者 万春利 葛盼丽 《山东中医杂志》 2024年第8期866-872,共7页
目的:探讨脊髓损伤患者进行动态四点跪位训练对髋关节骨密度及下肢运动功能的影响。方法:采用前瞻性随机对照研究方法,选取2019年1月至2022年1月收治的80例脊髓损伤患者,采用随机数字表法分为对照组与观察组各40例,对照组采用常规康复训... 目的:探讨脊髓损伤患者进行动态四点跪位训练对髋关节骨密度及下肢运动功能的影响。方法:采用前瞻性随机对照研究方法,选取2019年1月至2022年1月收治的80例脊髓损伤患者,采用随机数字表法分为对照组与观察组各40例,对照组采用常规康复训练+直立床训练,观察组采用常规康复训练+动态四点跪位训练,两组均连续干预12周。干预前及干预4周、8周、12周时,分别记录髋关节骨密度、下肢臀大肌及腘绳肌肌电信号、感觉评分、下肢运动功能评分(LEMS),股四头肌、臀大肌及腘绳肌的肌张力(改良Ashworth分级)和肌力,并统计两组不良事件(体位性低血压、膝关节疼痛、摩擦伤、跌倒)发生情况。结果:干预4周、8周、12周时,两组髋关节骨密度T-值均低于干预前,观察组高于对照组(P<0.05);干预4周、8周、12周时,两组表面肌电信号积分肌电值及LEMS均高于干预前,且观察组高于对照组(P<0.05);干预前及干预4周、8周、12周时,两组感觉评分差异无统计学意义(P>0.05);干预4周、8周、12周时,观察组肌张力低于对照组(P<0.05),肌力高于对照组(P<0.05);两组不良事件发生率比较差异无统计学意义(P>0.05)。结论:动态四点跪位训练可以在部分负重下通过动态训练刺激髋关节周围肌肉收缩以延缓脊髓损伤患者髋关节骨量流失,改善损伤平面以下下肢运动功能,且安全性较好。 展开更多
关键词 脊髓损伤 四点跪位训练 动态负重 髋关节密度 下肢运动功能
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Ankle fusion with a retrograde locked intramedullary nai for sequela of lower extremity compartment syndrome 被引量:2
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《Chinese Journal of Traumatology》 CAS 2012年第3期140-144,共5页
Objective: To assess the value of ankle fusion with a retrograde locked intramedullary nail in the treatment of sequela of lower extremity compartment syndrome. Methods: Thirty-five cases ofequinus deformity follow... Objective: To assess the value of ankle fusion with a retrograde locked intramedullary nail in the treatment of sequela of lower extremity compartment syndrome. Methods: Thirty-five cases ofequinus deformity follow- ing tibiofibular compartment syndrome treated by means of ankle fusion with a retrograde locked intramedullary nail from January 2001 to December 2010 were retrospectively reviewed. The complications, the time needed for bony fu- sion of the ankle joint assessed by anteroposterior and lateral X-ray photographs as well as patients' subjective evalua- tion were recorded and analysed. Results: Among the 35 patients, 15 had previously undergone surgical treatment twice on the same limb, 13 had thrice and 7 had to be operated on four times before ankle fusion. An anterior midpoint approach to the ankle joint was adopted in 29 cases, while anterior midpoint ap- proach plus a small incision on the posterior ankle joint was made in 17 cases, whereas lateral approach in 6 cases. Tar- sus joint fusion was performed on 4 cases. The follow-up period ranged 6-124 months, averaged 40.6 months. Bone grafting was not performed in this series. Preoperative tibial shaft fracture occurred in one patient and was healed after conservative treatment. Incision dehiscence located at pre- vious Achilles tendon incision was found in two patients. As a result, one received an intramedullary nail emplace- ment at calcaneoplantar part while the wound at anterosuperior part of the other one was healed by dressing change. Two patients failed to bony union 5 months postoperatively, in which one healed 10 weeks after retrieval of proximal tibial nail and another by iliac grafting. Terminal necrosis of the toe due to blood supply dysfunction was not found in this series. All the patients were satisfied with the ankle joint function postoperatively. The time for bony union on X-rays was 9.8 weeks on average. Except for one patient who demanded removal of intramedullary nail, all the intramedullary nails were not retrieved at the end of follow-up. Nail breakage happened in one patient and no other breakage or backing out of the nail was found. Conclusions: Lower extremity compartment syndrome and residual ankle deformity often extremely impact ambulation and are hard to deal with because several patho- logic phenomena might exist in these patients, for instance, poor skin conditions due to repeated preexisting surgery; poor perfusion in distal limbs following blood vascular injury; reflux limitation and long-term limb swelling due to muscle strength disturbance; osteoporosis as a result of long-term immobilization or limb disuse. Ankle fusion with a retro- grade locked intramedullary nail is an optimal protocol to solve these clinical symptoms and rather ensures a definite fusion and firm fixation to these patients with simple ma- nipulation and few complications. 展开更多
关键词 ANKLE Compartment syndromes lower extremity bone nails
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Clinicopathological features and treatment of extremity bone metastasis in patients with endometrial carcinoma: a case report and review 被引量:2
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作者 JIANG Guo-qing GAO Yu-nong GAO Min ZHENG Hong YAN Xin WANG Wen AN Na CAO Kun 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第4期622-626,共5页
Unlike other non-gynecologic solid tumors, such as breast cancer, lung cancer, metastasis to bone from endometrial carcinoma is rare, metastasis to extremity is extremely rare. We report a 51-year-old multiparous woma... Unlike other non-gynecologic solid tumors, such as breast cancer, lung cancer, metastasis to bone from endometrial carcinoma is rare, metastasis to extremity is extremely rare. We report a 51-year-old multiparous woman with FIGO Stage IVb Grade 2 endometrial adenocarcinoma which metastasized to left lower extremity bone. She received an amputation of left lower extremity below the knees, and a total abdominal hysterectomy and bilateral salpingo-oophorectomy, and followed by systemic chemotherapy, radiation therapy to the pelvis and progestational agent. She had a complete response to above treatments, and disease-free survival for 10 months. After recurrence, she received chemotherapy, radiotherapy and progestational agent once again. She had lived 56 months and is still alive by the time of report. Metastasis of endometrial carcinoma to extremity bone can rarely occur and should be considered when the patient with endometrial carcinoma complained of unexplained pain and swelling associated with extremity bone. 展开更多
关键词 endometrial carcinoma lower-extremity bone metastasis THERAPY CLINICOPATHOLOGICAL
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Influence of the intelligent standing mobile robot on lower extremity physiology of complete spinal cord injury patients 被引量:1
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作者 Jibao Chen Zhongxia Jin +5 位作者 Jiajia Yao Huifang Wang Yu Li Zengqiang Ouyang Yan Wang Wenxin Niu 《Medicine in Novel Technology and Devices》 2020年第3期13-17,共5页
Background:Spinal cord injury(SCI)remains a high rate of disability.In order to improve the quality of their lives,the application of robots in rehabilitation is increasing.However,few studies have assessed the applic... Background:Spinal cord injury(SCI)remains a high rate of disability.In order to improve the quality of their lives,the application of robots in rehabilitation is increasing.However,few studies have assessed the applicability and the effect of robots in patients with complete injury.Objective:The current study aims to assess the efficacy of robots training on the lower extremity physiology in complete SCI patients.Methods:24 patients were recruited and randomly divided into experimental and control group.The two groups spent the same amount of time on regular training.Besides,a 1-h standing training twice daily was offered to both groups five days per week,for four weeks.The experimental group used robot for standing training,while the control group used standing frame.Before and after the experiment,muscle girth and bone mineral density(BMD)were measured as lower extremity physiology.Results:The experimental group showed increased muscle girth differences(left=0.08±0.40 cm,right=0.75±0.72 cm),while the control group showed decreased girth differences(left=-0.78±0.54 cm,right=-0.56±0.54 cm).The increases in the experimental group showed significant differences compared with the control group(left,P=0.0002;right,P=0.023).Both groups showed decreased BMD.The decreases in the experimental group were significantly smaller than those in the control group.Conclusions:Training with aid of robots combined with the regular rehabilitation treatment can benefit complete SCI patients,in aspect of postponing amyotrophy of lower extremities and reducing bone loss and osteoporosis. 展开更多
关键词 Complete spinal cord injury Robot training lower extremity Muscle girth bone mineral density
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超声引导下神经阻滞联合全麻用于老年下肢骨折术中的效果
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作者 张衍平 李现虎 李康 《医学临床研究》 CAS 2024年第4期569-571,575,共4页
【目的】探讨超声引导下神经阻滞联合全麻用于老年下肢骨折术中的效果。【方法】268例接受下肢骨折术的老年患者,随机分为观察组(超声引导下神经阻滞联合全麻,134例)与对照组(全麻,134例)。比较两组麻醉效果、麻醉药物使用剂量、苏醒时... 【目的】探讨超声引导下神经阻滞联合全麻用于老年下肢骨折术中的效果。【方法】268例接受下肢骨折术的老年患者,随机分为观察组(超声引导下神经阻滞联合全麻,134例)与对照组(全麻,134例)。比较两组麻醉效果、麻醉药物使用剂量、苏醒时间、拔除喉罩时间、疼痛视觉模拟评分(VAS)及不良反应;比较两组不同时点的平均动脉压(MAP)、心率(HR)、凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)。【结果】观察组麻醉优良率高于对照组(P<0.05);观察组麻醉药物使用剂量少于对照组,苏醒时间、拔除喉罩时间短于对照组,术后VAS评分低于对照组(P<0.05);观察组插喉罩时(T_(1))、切皮时(T_(2))、拔喉罩时(T_(3))的MAP、HR与麻醉前(T_(0))比较,差异均无统计学意义(P>0.05),对照组在T_(1)、T_(2)、T_(3)时的MAP、HR均显著高于T_(0)时,观察组在T_(1)、T_(2)、T_(3)时的MAP、HR显著低于对照组(P<0.05);观察组在T_(2)、T_(3)时的PT、TT、APTT均显著高于对照组(P<0.05);观察组不良反应总发生率低于对照组(P<0.05)。【结论】超声引导下神经阻滞联合全麻对老年下肢骨折术患者血流动力学的影响较小,麻醉效果更好,围术期患者体征稳定,临床应用价值较高。 展开更多
关键词 骨折固定术 下肢骨 超声检查 神经传导阻滞 麻醉
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交锁髓内钉治疗创伤性下肢长管状骨骨折的临床效果
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作者 魏林 《中国医药指南》 2024年第13期114-116,共3页
目的 探究对创伤性下肢长管状骨骨折患者开展交锁髓内钉治疗的效果。方法 选取2021年1月至2022年12月南京市栖霞区医院收治的创伤性下肢长管状骨骨折患者140例,按随机数字表法分为对照组与试验组,两组各70例,对照组采用传统钢板内固定... 目的 探究对创伤性下肢长管状骨骨折患者开展交锁髓内钉治疗的效果。方法 选取2021年1月至2022年12月南京市栖霞区医院收治的创伤性下肢长管状骨骨折患者140例,按随机数字表法分为对照组与试验组,两组各70例,对照组采用传统钢板内固定术治疗,试验组采用交锁髓内钉内固定术治疗,对比两组手术重要指标、膝关节功能评分、术后疼痛度评分、关节恢复时间及术后并发症发生情况。结果 试验组手术出血量、手术时长、住院时长及术后关节功能恢复时间均短于对照组(均P <0.05);试验组疼痛、功能、活动度、屈曲畸形、肌力等膝关节功能评分均高于对照组(均P <0.05);两组疼痛度评分和并发症发生率均低于对照组(均P <0.05)。结论 运用交锁髓内钉内固定治疗法治疗创伤性下肢长管状骨骨折安全系数更高,能有效促进患者骨性愈合,减轻术后疼痛,避免关节功能障碍等并发症发生。 展开更多
关键词 创伤性下肢长管状骨骨折 交锁髓内钉 内固定
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The evolution of lower extremity reconstruction
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作者 Brogan G.A.Evans David L.Colen 《Plastic and Aesthetic Research》 2022年第1期182-195,共14页
Reconstruction of the lower extremity is a complex task that has evolved greatly in both technique and indication over the past century.Early advances in treating traumatic lower extremity injuries focused on primary ... Reconstruction of the lower extremity is a complex task that has evolved greatly in both technique and indication over the past century.Early advances in treating traumatic lower extremity injuries focused on primary amputation to avoid the high mortality of infection.The introduction of antibiotics improved surgical debridement and local reconstructive options,enhancing the viability of lower extremities with simple and proximal defects.With the advent of microvascular surgery,free tissue transfer techniques provided a means to reconstruct more distal and complex problems.As these surgical techniques have continued to evolve,so too have indications for reconstruction,patient management and post-operative care-now with a greater emphasis on patient quality of life and limb function.The purpose of this article is to outline the evolution of lower extremity reconstruction,and how the standard of practice has changed over time. 展开更多
关键词 lower extremity lower extremity reconstruction limb salvage free flap perforator flap vascularized bone flap orthoplastic surgery
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Review of soft tissue coverage options in distraction osteogenesis of the extremity
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作者 Jacqueline Stoneburner Beina Azadgoli +3 位作者 Anna C.Howell Douglass Tucker Geoffrey Marecek Joseph Carey 《Plastic and Aesthetic Research》 2020年第3期23-40,共18页
Aim:To review the choices of soft tissue coverage in distraction osteogenesis of the extremity.Methods:A PubMed literature search yielded 14 articles included for systematic review.Data were extracted from each articl... Aim:To review the choices of soft tissue coverage in distraction osteogenesis of the extremity.Methods:A PubMed literature search yielded 14 articles included for systematic review.Data were extracted from each article if available(sample size,patient age,surgical indications,type of flap,use of additional modalities,method of bone osteogenesis,postoperative events,follow-up,satisfaction,weight-bearing status,and success rate).Unpaired t-tests were performed to compare complication rates.A retrospective review of three cases was also conducted.Results:Fourteen articles discussed 145 patients with a mean age of 33.4 years and 146 extremity injuries followed over 3.3 years on average.Indications included chronic osteomyelitis or nonunion(58.2%)and acute trauma(41.8%).Average time from injury was 1.1 years.Ilizarov frame was used in 12 articles.Free flaps(88.0%)or rotational flaps(12.0%)were used,with muscle flaps(96.7%)being most common.Most extremities received free latissimus dorsi or rectus abdominis flaps.Bone grafts and antibiotic beads were often used in conjunction.Although complications and reoperations were not uncommon(up to 30%),98.8%of patients on average were ultimately weight bearing and all articles reported>91%success rate.Additionally,the rates of any complication were not statistically different between"fix and flap"protocol and flap or frame first.Lastly,a three-patient case series is presented.Conclusion:Bone transport with soft tissue reconstruction remains an excellent choice for patients with large bony defects or who are unable to undergo autologous bone grafting.Not one surgical approach to limb salvage is superior,and decision should be made on a case by case basis between the surgeon and the patient. 展开更多
关键词 Soft tissue coverage free flaps rotational flaps MICROsuRGERY bone osteogenesis bone transport lower extremity reconstruction limb salvage
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骨搬移技术治疗下肢长骨干慢性骨髓炎伴骨缺损术后骨性愈合不良的原因分析及对策 被引量:26
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作者 刘亦杨 沈立锋 +4 位作者 张春 郭峭峰 林炳远 黄凯 张展 《中国骨伤》 CAS 2018年第6期556-561,共6页
目的:探讨骨搬移技术治疗下肢长骨干慢性骨髓炎伴骨缺损术后出现骨性愈合不良的原因及其相应对策。方法:回顾性分析2012年6月至2015年12月采用骨搬移技术治疗的38例下肢长骨干慢性骨髓炎伴骨缺损患者的临床资料,男23例,女15例;年龄20~56... 目的:探讨骨搬移技术治疗下肢长骨干慢性骨髓炎伴骨缺损术后出现骨性愈合不良的原因及其相应对策。方法:回顾性分析2012年6月至2015年12月采用骨搬移技术治疗的38例下肢长骨干慢性骨髓炎伴骨缺损患者的临床资料,男23例,女15例;年龄20~56岁,平均36.5岁;股骨5例,胫骨33例;受伤至骨搬移时间2~19个月,平均7.4个月;骨缺损长度4~12 cm,平均7.3 cm;术后均经过1周"待机期"开始骨搬移,搬移方向由近端向远端30例,由远端向近端3例,双向搬移5例;并及时调整力线及骨搬移速度,患者坚持负重。定期随访,拍摄X线片,观察是否存在搬移间隙矿化成骨不良,对合端不愈合以及再发骨折等并发症;并采用Paley评分标准进行临床评价。结果:38例获得随访,时间12~36个月,平均23.1个月。骨髓炎无复发,但出现多种骨性愈合不良相关的并发症,其中骨搬移过程中发生搬移间隙矿化成骨不良3例,对合端不愈合17例,发生搬移间隙骨折5例,尚未拆除外固定架时发生骨折1例,拆除外固定架后发生骨折4例。带架时间9~27个月,平均16.3个月;外固定指数为1.7~2.7个月/cm,平均2.24个月/cm;根据Paley评分标准评定疗效:骨性结果优12例,良16例,中3例,差7例;功能结果优14例,良18例,中3例,差3例。结论:骨搬移技术有效解决了长骨干骨髓炎伴大段骨缺损的临床难题,但治疗周期长,对预后的影响因素多。因此,应严格适应证选择,同时应细致操作,全程监控,及时随访,并积极指导患者相应的预防策略,以期得到更满意的临床疗效。 展开更多
关键词 骨髓炎 骨折 不愈合 下肢骨 骨干
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外固定支架骨搬移技术对严重下肢感染骨缺损的治疗 被引量:13
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作者 陈辉 王爱民 +5 位作者 沈岳 曾礼学 赵玉峰 孙红振 郭庆山 唐颖 《重庆医学》 CAS CSCD 2008年第17期1961-1963,共3页
目的对32例下肢感染骨缺损患者临床资料进行系统性回顾性分析,探讨下肢感染骨缺损的细菌学特点、治疗策略以及治疗中常见的困难。方法32例下肢感染骨缺损患者中,男26例,女6例,17~50岁,平均34岁,股骨感染骨缺损11例,胫骨感染骨缺... 目的对32例下肢感染骨缺损患者临床资料进行系统性回顾性分析,探讨下肢感染骨缺损的细菌学特点、治疗策略以及治疗中常见的困难。方法32例下肢感染骨缺损患者中,男26例,女6例,17~50岁,平均34岁,股骨感染骨缺损11例,胫骨感染骨缺损21例,病程1个月至3年,平均1.2年。感染最早发生时间为骨折术后3d,最迟为3个月。其中开放性骨折27例,闭合性骨折5例,均行清创,灌洗引流、内固定取出、外固定支架固定、截骨延长骨搬移术。结果术前、术中细菌学培养32例均为阳性,其中金黄色葡萄球菌20例,溶血性链球菌6例,其他细菌6例。术后对27例患者随访,随访时间平均18个月,所有骨折全部得到愈合,愈合时间为6~12个月,平均9个月。结论(1)耐金黄色葡萄球菌是下肢骨折术后感染的最常见病原菌,其次为溶血性链球菌和铜绿假单胞菌;(2)下肢感染骨缺损手术治疗难度大,术前应作好周密的准备,不要轻易尝试;(3)手术方法采用I期或Ⅱ期清创、骨搬移术,手术清创应尽量彻底、去除死骨、术后敏感抗生素灌洗;(4)I期抗生素骨水泥填充感染骨缺损死腔可以提高疗效,有利于Ⅱ期骨搬移;(5)术后科学的康复治疗对功能恢复十分重要。 展开更多
关键词 下肢感染骨缺损 外固定支架 骨搬移
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右美托咪定对老年椎管内麻醉下肢骨折手术患者认知功能和应激反应的影响 被引量:45
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作者 罗海燕 唐文君 林玲 《解放军医药杂志》 CAS 2018年第12期105-108,共4页
目的探讨右美托咪定对老年椎管内麻醉下肢骨折手术患者认知功能和应激反应的影响。方法选取2015年5月—2017年5月收治的128例老年下肢骨折患者作为研究对象。根据用药不同将其分为对照组60例和观察组68例,对照组给予丙泊酚,观察组给予... 目的探讨右美托咪定对老年椎管内麻醉下肢骨折手术患者认知功能和应激反应的影响。方法选取2015年5月—2017年5月收治的128例老年下肢骨折患者作为研究对象。根据用药不同将其分为对照组60例和观察组68例,对照组给予丙泊酚,观察组给予右美托咪定。比较两组不同时间的应激反应相关指标及认知功能状况,并观察两组认知功能障碍和不良反应的发生率。结果用药后60 min和术毕,两组的去甲肾上腺素、肾上腺素和皮质醇水平均高于术前,但观察组低于对照组(P <0. 05)。术后2 h和24 h,两组的简易精神状态量表评分均低于术前1 d,但观察组高于对照组(P <0. 05)。观察组的认知功能障碍发生率及不良反应总发生率均显著低于对照组(P <0. 05)。结论右美托咪定可降低老年椎管内麻醉下肢骨折手术患者的应激反应,对认知功能有保护作用,且具有一定的安全性。 展开更多
关键词 骨折 下肢骨 右美托咪定 老年人 麻醉
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老年男性2型糖尿病患者下肢血管病变与骨质疏松的关系 被引量:11
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作者 杨虹 卢学勉 +2 位作者 林爱菊 黄贤恩 曾伟伟 《中国动脉硬化杂志》 CAS CSCD 北大核心 2010年第1期75-77,共3页
目的探讨老年男性2型糖尿病患者下肢血管病变与骨质疏松的关系。方法老年男性2型糖尿病患者148例,采用双能X线吸收法测定腰椎骨和股骨区的骨密度,同时用超声探测双下肢动脉内膜中膜厚度及粥样斑块等情况。结果无血管病变组33例,轻中度... 目的探讨老年男性2型糖尿病患者下肢血管病变与骨质疏松的关系。方法老年男性2型糖尿病患者148例,采用双能X线吸收法测定腰椎骨和股骨区的骨密度,同时用超声探测双下肢动脉内膜中膜厚度及粥样斑块等情况。结果无血管病变组33例,轻中度血管病变组65例,重度血管病变组50例,三组间骨密度值依次降低(P<0.05或0.01);多元Logistic回归分析显示,仅年龄、体质指数、下肢血管病变积分为决定骨质疏松的独立危险因素(OR值分别为1.50、0.52及1.87)。结论老年男性2型糖尿病下肢血管病变患者骨密度减低,骨质疏松风险增加。 展开更多
关键词 骨质疏松 2型糖尿病 下肢血管病变 骨密度
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自体骨髓单个核细胞移植治疗42例严重慢性下肢缺血性疾病 被引量:8
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作者 辛世杰 宋清斌 +8 位作者 胡海地 张健 秦岭峰 张赞松 张平 罗英伟 丁奎 白明欣 段志泉 《中国医科大学学报》 CAS CSCD 北大核心 2006年第6期627-630,F0003,共5页
目的:评价自体骨髓单个核细胞移植治疗严重慢性下肢缺血性疾病的效果和安全性。方法:2003年12月至2005年12月应用自体骨髓单个核细胞移植术治疗42例严重慢性下肢缺血性疾病,其中下肢动脉硬化闭塞症(ASO)22例、血栓闭塞性脉管炎(TAO)5例... 目的:评价自体骨髓单个核细胞移植治疗严重慢性下肢缺血性疾病的效果和安全性。方法:2003年12月至2005年12月应用自体骨髓单个核细胞移植术治疗42例严重慢性下肢缺血性疾病,其中下肢动脉硬化闭塞症(ASO)22例、血栓闭塞性脉管炎(TAO)5例、糖尿病足14例、下肢狼疮性动脉炎1例。术前多数患肢有轻重不同的静息痛,踝肱指数(ABI)均在0.6以下。随访时检查跛行距离、ABI、双下肢放射性核素扫描等客观指标。结果:患者手术1个月后开始随访,其中显著有效11例(26%)、有效16例(38%)、无效15例(36%),总有效率64%。糖尿病足、TAO、下肢狼疮性动脉炎3种疾病总有效率80%,ASO有效率50%,无手术并发症。结论:自体骨髓单个核细胞移植术能够增加患肢血流灌注,改善某些严重慢性下肢缺血性疾病的症状和体征。 展开更多
关键词 骨髓单个核细胞 自体移植 慢性下肢缺血性疾病 双下肢放射性核素扫描
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彩色多普勒血流显像筛查下肢骨折围手术期静脉血栓的价值及意义 被引量:26
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作者 徐志强 刘照宏 +3 位作者 李炎 方耀忠 梁峭嵘 廖荣宗 《中国医学影像技术》 CSCD 北大核心 2011年第3期552-555,共4页
目的观察CDFI筛查下肢骨折围手术期静脉血栓形成的价值及意义。方法回顾性分析1077例下肢骨折围手术期CDFI检查资料,重点观察下肢静脉有无血栓形成,累及部位、范围、声像图表现及血管腔阻塞等情况。结果 1077例患者,发现静脉血栓193例,... 目的观察CDFI筛查下肢骨折围手术期静脉血栓形成的价值及意义。方法回顾性分析1077例下肢骨折围手术期CDFI检查资料,重点观察下肢静脉有无血栓形成,累及部位、范围、声像图表现及血管腔阻塞等情况。结果 1077例患者,发现静脉血栓193例,阳性率17.92%(193/1077);其中术前发现171例,术后发现22例;急性血栓127例(127/193,65.80%),慢性血栓41例(41/193,21.24%),混合期血栓25例(25/193,12.95%);多发152例,单发41例。94.49%(120/127)的急性血栓发生在髂外静脉至胫后、腓静脉上段水平,68.29%(28/41)的慢性血栓发生在小腿肌肉静脉丛;82.38%(159/193)血栓致静脉大部分或完全阻塞,17.62%(34/193)血栓致静脉小部分阻塞。所有患者均接受抗凝溶栓治疗、植入腔静脉滤网等治疗,1例发生肺栓塞,积极抢救后痊愈。结论下肢骨折围手术期静脉血栓发生率较高。CDFI作为下肢骨折围手术期的常规检查项目非常必要,可为临床治疗提供重要参考依据。 展开更多
关键词 下肢 骨折 超声检查 多普勒 静脉 血栓形成
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全程康复护理对恶性骨肿瘤保肢治疗下肢功能的影响 被引量:11
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作者 蒋艳华 陈娟 沈利 《成都医学院学报》 CAS 2014年第1期94-96,共3页
目的探讨人工假体置换或异体骨植骨结合新辅助化疗方案治疗恶性骨肿瘤患者的康复护理要点。方法对36例接受人工假体置换或异体骨植骨结合新辅助化疗方案治疗恶性骨肿瘤患者,随机分为对照组(18例)和干预组(18例)。对照组给予常规康复护理... 目的探讨人工假体置换或异体骨植骨结合新辅助化疗方案治疗恶性骨肿瘤患者的康复护理要点。方法对36例接受人工假体置换或异体骨植骨结合新辅助化疗方案治疗恶性骨肿瘤患者,随机分为对照组(18例)和干预组(18例)。对照组给予常规康复护理,包括术前常规护理及康复指导、化疗护理、心理护理、术后常规康复护理;干预组在常规护理的基础上,采用全程康复护理模式进行护理。对两组患者术后1w、2w、1月下肢功能进行比较。结果干预组与对照组下肢功能在术后1w、2w、1月总体比较,差异有统计学意义(P<0.01);干预组下肢功能在术前、术后1w、术后2w、术后1月相比较,差异有统计学意义(P<0.01)。结论全程康复护理能有效帮助恶性骨肿瘤保肢治疗患者下肢功能的恢复。 展开更多
关键词 康复 护理 恶性骨肿瘤 保肢治疗 肢体功能
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脐带间充质干细胞联合骨髓干细胞治疗下肢缺血 被引量:6
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作者 杜俊文 吴韬 +5 位作者 张坤 苏白玉 卢彩萍 王伟超 雷琳 郭静霞 《中国组织工程研究》 CAS 北大核心 2017年第1期82-86,共5页
背景:骨髓干细胞移植治疗下肢缺血性疾病近年来在临床取得较大进步,但在实践过程中也发现由于老年患者骨髓干细胞数量较少,采集困难,分化能力降低,对临床疗效产生影响。目的:探讨脐带间充质干细胞联合骨髓干细胞治疗下肢缺血的效果。方... 背景:骨髓干细胞移植治疗下肢缺血性疾病近年来在临床取得较大进步,但在实践过程中也发现由于老年患者骨髓干细胞数量较少,采集困难,分化能力降低,对临床疗效产生影响。目的:探讨脐带间充质干细胞联合骨髓干细胞治疗下肢缺血的效果。方法:选择2012年3月至2015年11月在石家庄市第一医院进行干细胞移植治疗的下肢缺血性病变患者47例,根据治疗方法不同分为观察组23例和对照组24例,对照组采用骨髓干细胞移植治疗,观察组采用脐带间充质干细胞联合骨髓干细胞移植治疗。结果与结论:(1)观察组总有效率显著高于对照组(P=0.039);(2)观察组患者皮温、经皮氧分压和踝肱指数均显著高于对照组(P<0.05);(3)观察组患者肢体疼痛、患肢冷感和间歇性跛行评分均显著低于对照组(P<0.05);(4)由此可见脐带间充质干细胞联合骨髓干细胞治疗下肢缺血较单独采用骨髓干细胞能够更加有效提高患肢皮温、经皮氧分压和踝肱指数,改善患者疼痛及冷感等临床症状,疗效更佳。 展开更多
关键词 干细胞 移植 脐带间充质干细胞 骨髓干细胞 联合治疗 下肢缺血 效果
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MRI评价体操运动员下肢骨关节损伤 被引量:5
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作者 李勇 杨本涛 +2 位作者 王振常 刘舒 陈青华 《中国医学影像技术》 CSCD 北大核心 2009年第2期282-285,共4页
目的探讨MRI对评价体操运动员下肢骨关节损伤的价值。方法回顾性分析18例体操运动队员45次下肢MR检查结果.其中4例与X线平片、CT检查结果比较。结果45次MR检查包括足部3例11次、踝关节6例13次、膝关节4例6次以及髋关节6例15次。所有足... 目的探讨MRI对评价体操运动员下肢骨关节损伤的价值。方法回顾性分析18例体操运动队员45次下肢MR检查结果.其中4例与X线平片、CT检查结果比较。结果45次MR检查包括足部3例11次、踝关节6例13次、膝关节4例6次以及髋关节6例15次。所有足舟骨均变扁.并出现片状水肿,10次(90.91%)显示骨折线。所有胫骨远端骨骺变扁、碎裂,9次(69.23%)内踝、8次(61.54%)胫骨远端骨骺内出现大片水肿。3次(50.00%)股骨外侧髁、4次(66.67%)胫骨近端骨骺斑片状水肿;5次(83.33%)显示半月板退变,以内侧半月板后角几率最高(4/6)。5例13次股骨头变扁,并显示片状水肿;1例行9次检查显示了股骨头从损伤塌陷到逐渐恢复的过程。结论MRI检查可以早期全面地显示体操运动员运动损伤的全貌,为早期进行康复提供客观依据。 展开更多
关键词 磁共振成像 体操运动员 下肢 骨关节 运动损伤
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高能量损伤致下肢严重开放毁损伤行保肢治疗的临床研究 被引量:6
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作者 黄仁春 周世泰 +1 位作者 马飞 周新立 《陕西医学杂志》 CAS 2018年第8期1036-1038,共3页
目的:探讨高能量导致下肢严重开放毁损伤行保肢和重建治疗的临床效果。方法:选择下肢毁损伤患者共52例,根据治疗方法分为对照组22例和观察组30例,对照组行常规性手术,观察组采用保肢和重建手术;随访中位时间22.7个月,比较两组的并发症... 目的:探讨高能量导致下肢严重开放毁损伤行保肢和重建治疗的临床效果。方法:选择下肢毁损伤患者共52例,根据治疗方法分为对照组22例和观察组30例,对照组行常规性手术,观察组采用保肢和重建手术;随访中位时间22.7个月,比较两组的并发症发生率、再次手术率、住院时间和经济费用,生活质量和功能康复情况。结果:观察组总并发症率为13.3%,明显低于对照组(40.91%),两组比较差异有统计学意义(P<0.05);观察组再次手术率稍微高于对照组;而观察组住院时间和经济费用均优于对照组两组,比较差异有统计学意义(P<0.05);观察组生活质量评分和下肢功能评分均优于对照组,两组比较差异有统计学意义(P<0.05)。结论:综合评估下肢毁损伤程度、医院保肢能力及患者意愿,保肢和重建治疗有一定的应用安全性和有效性。 展开更多
关键词 下肢 创伤和损伤 截肢 创伤性 骨重建
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