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Intestinal Obstruction and Bowel Ischemia due to a Rare Left Paraduodenal Hernia: Case Report 被引量:1
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作者 Rani Alsairafi 《Surgical Science》 2022年第1期28-33,共6页
<p style="margin-left:10.0pt;"> <span style="font-family:Verdana;"><span style="font-family:Verdana;">Bowel obstruction is one of the most common problems found in outpa... <p style="margin-left:10.0pt;"> <span style="font-family:Verdana;"><span style="font-family:Verdana;">Bowel obstruction is one of the most common problems found in outpatient departments (OPDs) and emergency rooms. The challenge for surgeons is to be suspicious and recognizing rare disease that could cause bowel obstruction, such as paraduodenal hernia, without delaying the management as the risk of complications increase. This case study presents a patient with bowel obstruction secondary to a paraduodenal hernia.</span></span><span></span><span></span><span style="font-family:""></span> </p> 展开更多
关键词 Paraduodenal Hernia bowel Obstruction bowel ischemia
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Computed tomography findings of pneumatosis and portomesenteric venous gas in acute bowel ischemia 被引量:15
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作者 Marco Milone Matteo Nicola Dario Di Minno +4 位作者 Mario Musella Paola Maietta Vittorio Iaccarino Giovanni Barone Francesco Milone 《World Journal of Gastroenterology》 SCIE CAS 2013年第39期6579-6584,共6页
AIM:To use more representative sample size to evaluate whether computed tomography(CT)scan evidence of the concomitant presence of pneumatosis and portomesenteric venous gas is a predictor of transmural bowel necrosis... AIM:To use more representative sample size to evaluate whether computed tomography(CT)scan evidence of the concomitant presence of pneumatosis and portomesenteric venous gas is a predictor of transmural bowel necrosis.METHODS:Data from 208 patients who were referred for a diagnosis of bowel ischemia were retrospectively reviewed.Only patients who underwent a surgical intervention following a diagnosis of bowel ischemia who also had a post-operative histological confirmation of such a diagnosis were included.Patients were split into two groups according to the presence of histological evidence of transmural bowel ischemia(case group)or partial bowel ischemia(control group).CT images were reviewed for findings of ischemia,including mural thickening,pneumatosis,bowel distension,portomesenteric venous gas and arterial or venous thrombi.RESULTS:A total of 248 subjects who underwent surgery for bowel ischemia were identified.Among the208 subjects enrolled in our study,transmural bowel necrosis was identified in 121 subjects(case group),and partial bowel necrosis was identified in 87 subjects(control group).Based on CT findings,including mural thickening,bowel distension,pneumatosis,pneumatosis plus portomesenteric venous gas and presence of thrombi or emboli,there were no significant differences between the case and control groups.The concomitant presence of pneumatosis and porto-mesenteric venous gas showed an odds ratio of 1.95(95%CI:0.491-7.775,P=0.342)for the presence of transmural necrosis.The presence of pneumatosis plus porto-mesenteric venous gas exhibited good specificity(83%)but low sensitivity(17%)in the identification of transmural bowel infarction.Accordingly,the positive and negative predictive values were 60% and 17%,respectively.CONCLUSION:Although pneumatosis plus porto-mesenteric venous gas is associated with bowel ischemia,we have demonstrated that their co-occurrence cannot be used as diagnostic signs of transmural necrosis. 展开更多
关键词 bowel ischemia PNEUMATOSIS MESENTERIC VENOUS GAS COMPUTED tomography
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Successful management of adhesion related small bowel ischemia without intestinal resection: A case report and review of literature
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作者 Pantelis Vassiliu Vasiliki Ntella +5 位作者 George Theodoroleas Zisis Mantanis Ioanna Pentara Eleni Papoutsi Aikaterini Mastoraki Nikolaos Arkadopoulos 《World Journal of Gastrointestinal Pathophysiology》 CAS 2019年第2期29-35,共7页
BACKGROUND Intraabdominal adhesions develop spontaneously or after an inflammatory process or surgical procedure in the abdomen.They are the most common cause of small bowel obstruction(SBO).SBO occasionally leads to ... BACKGROUND Intraabdominal adhesions develop spontaneously or after an inflammatory process or surgical procedure in the abdomen.They are the most common cause of small bowel obstruction(SBO).SBO occasionally leads to intestinal ischemia(In Is)which can be a life-threatening condition that requires management as soon as possible.We herein report a case of SBO with In Is presented in our institution and treated without intestinal resection.CASE SUMMARY A 34-year-old man presented at the emergency department after a 12-h-onset diffuse abdominal pain,bloating and nausea.He had a history of traumatic right hepatectomy 11 years ago as well as adhesiolysis and resection of a long part of small bowel 2 years ago.An abdominal computed tomography(CT)showed dilated loops that led to the diagnosis of SBO.Due to deteriorating lactic acidosis,the patient was operated.Torsion of the small bowel around an adhesion led to2.30 m of ischemic ileum.After the application of N/S 40°C for 20 min,the intestine showed signs of improvement and it was decided to avoid resection and instead temporary close the abdomen with vacuum-pack technique.At the second-look laparotomy 48 h later,the intestine appeared normal.The patient was discharged on the 8 th post-op day in excellent condition.CONCLUSION In case of SBO caused by adhesions,extreme caution is needed if In Is is present,as the clinical signs are mild and you should rely for diagnosis in CT findings and lactate levels.Conservative surgical approach could reverse the effects of In Is,if performed quickly,so that intestinal resection is avoided and should be used even when minimum signs of viability are present. 展开更多
关键词 INTRAABDOMINAL ADHESIONS Intestinal ischemia Small bowel OBSTRUCTION Vacuum-pack technique Case report Conservative surgical approach
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Multi-detector CT features of acute intestinal ischemia and their prognostic correlations 被引量:9
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作者 Marco Moschetta Michele Telegrafo +2 位作者 Leonarda Rella Amato Antonio Stabile Ianora Giuseppe Angelelli 《World Journal of Radiology》 CAS 2014年第5期130-138,共9页
Acute intestinal ischemia is an abdominal emergency occurring in nearly 1% of patients presenting with acute abdomen. The causes can be occlusive or non occlusive. Early diagnosis is important to improve survival rate... Acute intestinal ischemia is an abdominal emergency occurring in nearly 1% of patients presenting with acute abdomen. The causes can be occlusive or non occlusive. Early diagnosis is important to improve survival rates. In most cases of late or missed diagnosis, the mortality rate from intestinal infarction is very high, with a reported value ranging from 60% to 90%. Multidetector computed tomography(MDCT) is a fundamental imaging technique that must be promptly performed in all patients with suspected bowel ischemia. Thanks to the new dedicated reconstruction program, its diagnostic potential is much improved compared to the past and currently it is superior to that of any other noninvasive technique. The increased spatial and temporal resolution, high-quality multi-planar reconstructions, maximum intensity projections, vessel probe, surface-shaded volume rending and tissue transition projections make MDCT the gold standard for the diagnosis of intestinal ischemia, with reported sensitivity, specificity, positive and negative predictive values of 64%-93%, 92%-100%, 90%-100% and 94%-98%, respectively. MDCT contributes to appropriate treatment planning and provides important prognostic informationthanks to its ability to define the nature and extent of the disease. The purpose of this review is to examine the diagnostic and prognostic role of MDCT in bowel ischemia with special regard to the state of art new reconstruction software. 展开更多
关键词 Multi-detector COMPUTED tomography bowel ischemia MESENTERIC INFARCTION
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Acute arterial mesenteric ischemia and reperfusion:Macroscopic and MRI findings, preliminary report 被引量:5
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作者 Luca Saba Daniela Berritto +6 位作者 Francesca Iacobellis Mariano Scaglione Sigismondo Castaldo Santolo Cozzolino Maria Antonietta Mazzei Veronica Di Mizio Roberto Grassi 《World Journal of Gastroenterology》 SCIE CAS 2013年第40期6825-6833,共9页
AIM:To explore the physiopathology and magnetic resonance imaging(MRI)findings in an animal model of acute arterial mesenteric ischemia(AAMI)with and without reperfusion.METHODS:In this study,8 adult Sprague-Dawley ra... AIM:To explore the physiopathology and magnetic resonance imaging(MRI)findings in an animal model of acute arterial mesenteric ischemia(AAMI)with and without reperfusion.METHODS:In this study,8 adult Sprague-Dawley rats underwent superior mesenteric artery(SMA)ligation and were then randomly divided in two groups of 4.In groupⅠ,the ischemia was maintained for 8 h.In groupⅡ,1-h after SMA occlusion,the ligation was removed by cutting the thread fixed on the back of the animal,and reperfusion was monitored for 8 h.MRI was performed using a 7-T system.RESULTS:We found that,in the case of AAMI without reperfusion,spastic reflex ileus,hypotonic reflex ileus,free abdominal fluid and bowel wall thinning are present from the second hour,and bowel wall hyperintensity in T2-W sequences are present from the fourth hour.The reperfusion model shows the presence of early bowel wall hyperintensity in T2-W sequences after 1 h and bowel wall thickening from the second hour.CONCLUSION:Our study has shown that MRI can assess pathological changes that occur in the small bowel and distinguish between the presence and absence of reperfusion after induced acute arterial ischemia. 展开更多
关键词 ACUTE ARTERIAL MESENTERIC ischemia REPERFUSION Magnetic resonance imaging Animal model Superior MESENTERIC artery bowel ischemia
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Early diagnosis of bowel obstruction and strangulation by computed tomography in emergency department 被引量:3
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作者 Sohil Pothiawala Apoorva Gogna 《World Journal of Emergency Medicine》 CAS 2012年第3期227-231,共5页
Closed loop bowel obstruction is a specific type of mechanical obstruction with a high risk of strangulation and bowel infarction, especially in the small bowel. It is associated with a high mortality rate. Hence, it ... Closed loop bowel obstruction is a specific type of mechanical obstruction with a high risk of strangulation and bowel infarction, especially in the small bowel. It is associated with a high mortality rate. Hence, it is important for emergency physicians to identify the presence of strangulation, while making the diagnosis of closed loop small bowel obstruction. We reported three patients with strangulated closed loop small bowel obstruction associated with severe abdominal pain, who had been treated at the emergency department. Urgent computerized tomography was performed in the patients. Two patients were discharged with stable conditions, and one patient died after hemodialysis. Urgent computerized tomography of the abdomen serves as an important diagnostic tool in view of its ability to detect the site, level and cause of obstruction along with the distinctive CT appearance of closed loop small bowel obstruction and signs of ischemia. Early definitive diagnosis will guide subsequent management and improve outcomes. 展开更多
关键词 Closed loop small bowel obstruction Computed tomography ischemia STRANGULATION
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缺血性肠病的临床特点及治疗 被引量:16
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作者 樊庆 吴问汉 +2 位作者 冯秋实 杨尹默 万远廉 《中国现代医学杂志》 CAS CSCD 北大核心 2008年第10期1434-1437,1440,共5页
目的总结缺血性肠病,尤其是急性缺血性肠病的临床特点和治疗经验。方法回顾性分析该院自2002年2月~2006年11月间诊断及治疗的缺血性肠病患者共18例,其中急性发病患者共9例。结果18例患者中,手术治疗8例,介入治疗4例,保守治疗6例,17例... 目的总结缺血性肠病,尤其是急性缺血性肠病的临床特点和治疗经验。方法回顾性分析该院自2002年2月~2006年11月间诊断及治疗的缺血性肠病患者共18例,其中急性发病患者共9例。结果18例患者中,手术治疗8例,介入治疗4例,保守治疗6例,17例患者痊愈出院,死亡1例。早期确诊率为50%。结论缺血性肠病早期症状不典型,确诊困难较大,容易延误诊断,预后较差。尤其是急性缺血性肠病病情重,进展快,死亡率很高。影像学检查对该病的早期诊断有较大帮助。 展开更多
关键词 肠系膜血管 缺血性 肠病
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急性肠缺血的CT征象分析 被引量:7
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作者 李征宇 陈海曦 张贵祥 《中国医学计算机成像杂志》 CSCD 2005年第4期251-254,共4页
目的:分析急性肠缺血的CT征象,提高CT对急性肠缺血诊断的准确性.材料和方法:2004~2005年间经急诊CT平扫及增强扫描,53例被诊断为急性肠缺血,分析其CT征象并与临床治疗和手术结果相对照.结果:CT平扫及增强图像显示:①肠腔扩张及积液53例... 目的:分析急性肠缺血的CT征象,提高CT对急性肠缺血诊断的准确性.材料和方法:2004~2005年间经急诊CT平扫及增强扫描,53例被诊断为急性肠缺血,分析其CT征象并与临床治疗和手术结果相对照.结果:CT平扫及增强图像显示:①肠腔扩张及积液53例次.②肠壁增厚伴密度改变39例次,其中平扫时肠壁内见散在点状高密度影7例次,肠壁密度降低22例次.增强扫描肠壁黏膜层异常强化15例次.③肠系膜血管走行异常并血管增粗(漩涡征)10例.④肠系膜脂肪水肿及渗出(缆绳征)26例.⑤肠系膜动脉钙化斑26例;其中有5例可见肠系膜动脉内等密度无强化的血栓影;另3例经手术证实肠系膜上动脉近肠小血管襻内血栓形成,但CT未能显示.⑥肠系膜静脉血栓形成4例.全部53例病人中,39例内科保守治疗后好转,14例症状未缓解者,经外科手术治疗,证实10例为肠系膜动脉血栓形成(其中3例CT未显示血栓),4例为门静脉血栓形成.结论:肠腔扩张和积液、肠壁增厚、肠系膜血管缆绳征及腹水是急性肠缺血的CT间接征象.CT平扫结合MDCT增强和CTA图像显示肠壁内密度改变、肠系膜血管内血栓形成或血管硬化导致管腔狭窄、漩涡征,即可确诊. 展开更多
关键词 肠缺血 CT X线征象 CT征象分析 急性肠缺血 肠系膜静脉血栓形成 肠系膜血管 门静脉血栓形成 CT平扫 图像显示
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Hepatic portal venous gas: Physiopathology, etiology, prognosis and treatment 被引量:33
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作者 Bassam Abboud Jad El Hachem +1 位作者 Thierry Yazbeck Corinne Doumit 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第29期3585-3590,共6页
Hepatic portal venous gas (HPVG), an ominous radiologic sign, is associated in some cases with a severe underlying abdominal disease requiring urgent operative intervention. HPVG has been reported with increasing freq... Hepatic portal venous gas (HPVG), an ominous radiologic sign, is associated in some cases with a severe underlying abdominal disease requiring urgent operative intervention. HPVG has been reported with increasing frequency in medical literature and usually accompanies severe or lethal conditions. The diagnosis of HPVG is usually made by plain abdominal radiography, sonography, color Doppler flow imaging or computed tomography (CT) scan. Currently, the increased use of CT scan and ultrasound in the inpatient setting allows early and highly sensitive detection of such severe illnesses and also the recognition of an increasing number of benign and non-life threatening causes of HPVG. HPVG is not by itself a surgical indication and the treatment depends mainly on the underlying disease. The prognosis is related to the pathology itself and is not influenced by the presence of HPVG. Based on a review of the literature, we discuss in this paper the pathophysiology, risk factors, radiographic findings, management, and prognosis of pathologies associated with HPVG. 展开更多
关键词 Hepatic portal venous gas bowel ischemia/necrosis DIVERTICULITIS Gastric pathologies Ulcerativecolitis Abdominal computed tomography scan Crohn'sdisease Liver transplantation Chemotherapy
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Henoch-Schonlein purpura from vasculitis to intestinal perforation: A case report and literature review 被引量:7
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作者 Butsabong Lerkvaleekul Suporn Treepongkaruna +4 位作者 Pawaree Saisawat Pornsri Thanachatchairattana Napat Angkathunyakul Nichanan Ruangwattanapaisarn Soamarat Vilaiyuk 《World Journal of Gastroenterology》 SCIE CAS 2016年第26期6089-6094,共6页
Henoch-Sch?nlein purpura(HSP) is generally a selflimited vasculitis disease and has a good prognosis. We report a 4-year-old Thai boy who presented with palpable purpura, abdominal colicky pain, seizure, and eventuall... Henoch-Sch?nlein purpura(HSP) is generally a selflimited vasculitis disease and has a good prognosis. We report a 4-year-old Thai boy who presented with palpable purpura, abdominal colicky pain, seizure, and eventually developed intestinal ischemia and perforation despite adequate treatment, including corticosteroid and intravenous immunoglobulin therapy. Imaging modalities, including ultrasonography and contrastenhanced computed tomography, could not detect intestinal ischemia prior to perforation. In this patient, we also postulated that vasculitis-induced mucosal ischemia was a cause of the ulcer, leading to intestinal perforation, and high-dose corticosteroid could have been a contributing factor since the histopathology revealed depletion of lymphoid follicles. Intestinal perforation in HSP is rare, but life-threatening. Close monitoring and thorough clinical evaluation are essential to detect bowel ischemia before perforation, particularly in HSP patients who have hematochezia, persistent localized abdominal tenderness and guarding. In highly suspicious cases, exploratory laparotomy may be needed for the definite diagnosis and prevention of further complications. 展开更多
关键词 Henoch-Schonlein purpura CORTICOSTEROIDS VASCULITIS Intestinal perforation bowel ischemia PERITONITIS
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肠缺血病变的MSCT诊断 被引量:2
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作者 王保海 孙静涛 +4 位作者 李倩 王来友 王东平 刘晓军 周小森 《CT理论与应用研究(中英文)》 2017年第1期77-84,共8页
目的:探讨肠缺血病变的MSCT表现及对其诊断价值,为临床治疗提供帮助。资料和方法:回顾性分析经DSA、手术、病理或临床最终确诊证实的55例肠缺血性病变患者行MSCT平扫及增强检查资料,对病变的部位、范围、病变段肠管的强化程度、相关的... 目的:探讨肠缺血病变的MSCT表现及对其诊断价值,为临床治疗提供帮助。资料和方法:回顾性分析经DSA、手术、病理或临床最终确诊证实的55例肠缺血性病变患者行MSCT平扫及增强检查资料,对病变的部位、范围、病变段肠管的强化程度、相关的肠道外征象以及CTA进行诊断分析。结果:55例中,肠系膜上动脉栓塞或血栓形成13例,肠系膜上静脉血栓形成22例,缺血性结肠炎2例,肠扭转6例,粘连性肠梗阻5例,肠套叠4例及腹内疝3例。MSCT及CTA表现:肠腔扩张积液41例,肠系膜水肿33例(缆绳征5例、脂肪浑浊征27例,积气1例),肠系膜血管走行异常17例(漩涡征5例,位置异常10例)及血管充盈缺损或狭窄35例。结论:MSCT对肠缺血病变显示敏感性高,且表现具有一定特征性,应作为常规和首选,同时密切结合临床,不仅对肠缺血病变能做出正确诊断,而且在查找病因、鉴别诊断等方面都有重要作用,为临床精准治疗提供依据。 展开更多
关键词 肠缺血 体层摄影术 X线计算机
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实验性小肠闭袢性肠梗阻肠壁缺血程度与时间相关性的CT分析 被引量:6
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作者 黄小华 张小明 +4 位作者 董国礼 杨汉丰 唐显映 杨正伟 周继雍 《放射学实践》 2006年第10期981-984,共4页
目的:建立兔小肠闭袢性肠梗阻模型,通过螺旋CT多期扫描,观察小肠闭袢性肠梗阻肠壁缺血程度与时间的相关性。方法:新西兰大白兔54只,随机分为A、B、C三组。A组9只,结扎长约10~15cm的小肠两端,形成单纯性闭袢;B组30只,除按A组... 目的:建立兔小肠闭袢性肠梗阻模型,通过螺旋CT多期扫描,观察小肠闭袢性肠梗阻肠壁缺血程度与时间的相关性。方法:新西兰大白兔54只,随机分为A、B、C三组。A组9只,结扎长约10~15cm的小肠两端,形成单纯性闭袢;B组30只,除按A组形成单纯性闭袢外,同时结扎闭袢肠段的引流静脉;C组15只,在B组的基础上,同时结扎闭袢肠段的供血动脉。术后在不同的时间点行螺旋CT多期扫描。根据小肠梗阻肠壁缺血程度的CT标准,回顾性分析不同程度肠壁缺血所对应的缺血时间。结果:A组在随机的各时间内均表现为轻度肠缺血,缺血时间(107.11±71.65)min;B组表现为轻度、中度和重度肠缺血,其对应的缺血时间分别为(36.11±9.56)min、(98.77±39.12)min和(250.75±52.00)min;C组在随机的各时间内表现为中度肠缺血和重度肠缺血,其对应的缺血时间分别为(30.50±11.91)min和(150.11±71.62)min。结论:根据小肠梗阻的类型,结合螺旋CT多期扫描,可估计小肠肠壁的缺血程度所对应的缺血时间。缺血程度和缺血时间的确定,可为临床治疗方案的选择提供参考。 展开更多
关键词 肠梗阻 缺血 体层摄影术 X线计算机 动物实验
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急性肠缺血的MSCT诊断价值探讨 被引量:9
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作者 言伟强 刘晓杰 +4 位作者 刘远健 江锦赵 方玲 王成林 刘鹏程 《罕少疾病杂志》 2007年第5期34-36,共3页
目的评价MSCT对急性肠缺血(AMI)的诊断价值。方法回顾性分析5例AMI患者的平扫、动脉期、门静脉期和MSCT肠系膜血管成像(MSCTA)图像,描述AMI的肠系膜血管及其相关病变MSCT的表现特点。结果5个病例中,1例肠系膜血管显示正常。肠系膜上动脉... 目的评价MSCT对急性肠缺血(AMI)的诊断价值。方法回顾性分析5例AMI患者的平扫、动脉期、门静脉期和MSCT肠系膜血管成像(MSCTA)图像,描述AMI的肠系膜血管及其相关病变MSCT的表现特点。结果5个病例中,1例肠系膜血管显示正常。肠系膜上动脉(SMA)梗塞2例,其中1例断面图像表现为SMA起始端以远血管腔内无对比剂充盈,MSCTA示SMA起始端以远未显影;另1例断面图像SMA未见明显异常,MSCTA显示SMA近端局限性狭窄,血管壁明显增厚。肠系膜上静脉梗塞(SMV)2例,其中1例SMV完全闭塞,管腔内无对比剂充盈,MSCTA示SMV和门静脉均未显影;另1例SMV内见充盈缺损影,MSCTA示SMV内见条状低密度影。5例均见小肠病变肠管壁明显增厚、肿胀,肠管积液扩张及腹水,2例见肠系膜水肿,2例并肠壁积气。结论MSCT能准确显示AMI的肠系膜血管及相关病变情况,是AMI的理想检查方法。 展开更多
关键词 肠缺血 肠系膜 血栓形成 体层摄影术 X线计算机
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肠系膜动脉供血障碍性肠缺血肠管可逆性CT表现探讨 被引量:3
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作者 高云 郑晓林 +1 位作者 杨沛钦 桂国华 《影像诊断与介入放射学》 2016年第4期311-315,共5页
目的探讨肠系膜上动脉和肠系膜下动脉供血障碍肠管可逆性改变的MSCT表现。方法回顾性分析21例经治疗恢复的肠缺血患者的CT表现特征,观察病变肠系膜上动脉、肠系膜下动脉表现及相应供血肠管的异常表现,将缺血肠管与正常对照组肠壁CT表现... 目的探讨肠系膜上动脉和肠系膜下动脉供血障碍肠管可逆性改变的MSCT表现。方法回顾性分析21例经治疗恢复的肠缺血患者的CT表现特征,观察病变肠系膜上动脉、肠系膜下动脉表现及相应供血肠管的异常表现,将缺血肠管与正常对照组肠壁CT表现进行比较,所得的数据进行统计学分析。结果 21例中,肠系膜上动脉病变14例,肠系膜下动脉病变2例,5例肠系膜上、下动脉均有异常。19例小肠缺血表现为肠管扩张,管径为20.05±1.99 mm,管径大于正常对照组(15.36±0.74 mm,P<0.05);肠腔内积液13例,例数多于对照组(P<0.05)。于静脉期增强,小肠壁呈不均匀强化,平均CT值为42.77±4.33 HU,低于对照组(85.53±2.68 HU,P<0.05),小肠黏膜强化中断16例,例数高于对照组(P<0.05)。7例结肠缺血患者,肠管的径线为24.02±1.55 mm,对照组径线为19.73±1.88 mm,两者差异无统计意义(P>0.05);结肠肠腔内积液3例,与对照组(2例积液)比较无统计学差异(P>0.05);静脉期增强,病变结肠壁平均CT值为33.14±4.02 HU,低于对照组(CT值为63.63±6.50 HU,P<0.05);病变结肠黏膜强化连续性中断5例,对照组结肠黏膜强化连续性中断2例,两者比较无统计学差异(P>0.05)。以上小肠和结肠的缺血性改变,治疗后复查均恢复正常。结论肠系膜动脉供血障碍性肠缺血可逆性改变的多排螺旋CT征象为肠管轻度扩张,肠腔内积液增多,肠管壁不均匀强化、肠黏膜强化不连续,而小肠改变较结肠改变显著,是诊断可逆肠缺血的重要依据,具有一定的临床价值。 展开更多
关键词 肠缺血 体层摄影术 X线计算机 对照分析
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诱导血红素氧合酶-1对小肠移植缺血再灌注损伤的影响 被引量:1
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作者 肇毅 华一兵 +4 位作者 陈涛 王海权 王一芳 沈历宗 吴文溪 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2006年第9期857-860,F0004,共5页
目的:探讨诱导血红素氧合酶-1(HO-1)是否可减轻大鼠小肠移植缺血再灌注损伤及其机制。方法:SD大鼠分成3组:Ⅰ组:血晶素(Hemin)组(n=20);Ⅱ组:Hemin+卟啉锌(ZnPP)组(n=20);Ⅲ组:生理盐水组(n=20)。建立小肠移植缺血再灌注损伤模型。移植... 目的:探讨诱导血红素氧合酶-1(HO-1)是否可减轻大鼠小肠移植缺血再灌注损伤及其机制。方法:SD大鼠分成3组:Ⅰ组:血晶素(Hemin)组(n=20);Ⅱ组:Hemin+卟啉锌(ZnPP)组(n=20);Ⅲ组:生理盐水组(n=20)。建立小肠移植缺血再灌注损伤模型。移植后6、12、24、48h分别从各组随机取5只大鼠,切取移植小肠进行HO-1活性测定,普通病理学检查及细胞凋亡检测。结果:术后各时段Ⅰ组HO-1活性均显著强于Ⅱ组及Ⅲ组(P<0.05),而Ⅱ组和Ⅲ组比较无显著差异(P>0.05)。各组移植肠缺血再灌注损伤以术后12h最为明显。Ⅰ组表现轻度,而Ⅱ组和Ⅲ组表现中度缺血再灌注损伤。术后各时段Ⅰ组细胞凋亡数少于Ⅱ组和Ⅲ组,差别有统计学意义(P<0.05),而Ⅱ组和Ⅲ组比较无统计学意义(P>0.05)。结论:诱导HO-1可通过抑制细胞凋亡而减轻移植肠缺血再灌注损伤。 展开更多
关键词 小肠移植 缺血再灌注损伤 血红素氧合酶-1 大鼠
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老年患者肠系膜上动脉钙化性病变的CT影像学分析 被引量:5
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作者 邹循锋 顾腾辉 +1 位作者 顾建华 谭志军 《天津医药》 CAS 2017年第10期1049-1052,共4页
目的回顾性分析老年患者腹主动脉及肠系膜上动脉(SMA)粥样硬化与缺血性肠病(IBD)的相关性。方法选取本院2010年1月—2015年12月住院期间确诊IBD的老年患者20例(IBD组)及同期住院无IBD的老年冠心病患者20例(对照组),利用Syngo.Via软件对... 目的回顾性分析老年患者腹主动脉及肠系膜上动脉(SMA)粥样硬化与缺血性肠病(IBD)的相关性。方法选取本院2010年1月—2015年12月住院期间确诊IBD的老年患者20例(IBD组)及同期住院无IBD的老年冠心病患者20例(对照组),利用Syngo.Via软件对比分析2组患者腹主动脉及SMA的CT影像学资料。结果 CT影像资料显示老年患者的钙化斑块在对照组中以点状为主,而在IBD组中以条形斑块为主,部分甚至融合为环状。IBD组中SMA的钙化斑块总数较对照组明显增多(χ~2=5.010,P=0.025),管腔狭窄更明显(Z=3.370,P=0.001)。在IBD组中,SMA病变程度与其开口狭窄程度呈正相关(r_s=0.650,P=0.002)。结论 SMA点状钙化斑块是冠心病老年人血管病变基础,大块斑块及其导致的SMA开口狭窄是引起老年人动脉粥样硬化性IBD的主要原因。 展开更多
关键词 腹主动脉钙化 缺血性肠病 肠系膜上动脉钙化 CT影像
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提高缺血性肠病的临床认识 被引量:45
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作者 范建高 沈峰 《胃肠病学和肝病学杂志》 CAS 2011年第6期491-494,共4页
缺血性肠病是一组因小肠、结肠血液供应不足导致的不同程度的肠壁局部组织坏死和一系列症状的疾病,可分为急性肠系膜缺血(AMI)、慢性肠系膜缺血(CMI)及缺血性结肠炎(IC),以IC最多见。临床表现主要为腹痛、血性腹泻、血便及腹胀等消化道... 缺血性肠病是一组因小肠、结肠血液供应不足导致的不同程度的肠壁局部组织坏死和一系列症状的疾病,可分为急性肠系膜缺血(AMI)、慢性肠系膜缺血(CMI)及缺血性结肠炎(IC),以IC最多见。临床表现主要为腹痛、血性腹泻、血便及腹胀等消化道症状。该病与动脉粥样硬化、肠系膜动静脉栓塞及血栓形成、心搏量减少及血管炎等有关,患者可同时存在高血压、糖尿病及急性心肌梗死等老龄化疾病。DSA及CT检查对于诊断AMI及CMI价值较高,而IC则主要依赖于结肠镜的诊断。预后也各不相同,AMI病情凶险,死亡率高,须早期诊断及手术治疗;而IC临床症状多为自限性,预后良好。缺血性肠病临床误诊率较高,应引起临床医师重视。 展开更多
关键词 缺血性肠病 急性肠系膜缺血 慢性肠系膜缺血 缺血性结肠炎 流行病学 病因学
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肠康复治疗用于缺血性肠功能障碍 被引量:3
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作者 韩建明 李为苏 +1 位作者 吴性江 黎介寿 《肠外与肠内营养》 CAS 2004年第4期209-211,215,共4页
目的 :总结肠康复治疗用于急性肠系膜缺血所致肠功能障碍的经验。 方法 :对 2例急性肠系膜缺血病人 ,在早期治疗中保留生机不确定的肠管 ,设法尽早恢复肠道血供 ,术后肠功能障碍给予肠外、肠内营养支持 +谷氨酰胺 +生长激素 +膳食纤维... 目的 :总结肠康复治疗用于急性肠系膜缺血所致肠功能障碍的经验。 方法 :对 2例急性肠系膜缺血病人 ,在早期治疗中保留生机不确定的肠管 ,设法尽早恢复肠道血供 ,术后肠功能障碍给予肠外、肠内营养支持 +谷氨酰胺 +生长激素 +膳食纤维行肠康复治疗。 结果 :肠康复治疗结束后 ,肠功能恢复 ,饮食正常。 结论 展开更多
关键词 肠康复 缺血性肠功能障碍 肠功能障碍 急性肠系膜缺血
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缺血性肠病224例临床分析 被引量:7
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作者 张艳飞 顾芳 《实用老年医学》 CAS 2017年第6期536-539,547,共5页
目的总结缺血性肠病的临床特点,对老年和非老年病人进行对比分析。方法回顾性分析224例缺血性肠病的临床资料,比较不同影像学检查的诊断价值,对老年组(≥60岁,127例)和非老年组(<60岁,97例)的既往病史、临床症状及结肠镜下表现进行... 目的总结缺血性肠病的临床特点,对老年和非老年病人进行对比分析。方法回顾性分析224例缺血性肠病的临床资料,比较不同影像学检查的诊断价值,对老年组(≥60岁,127例)和非老年组(<60岁,97例)的既往病史、临床症状及结肠镜下表现进行对比分析。结果缺血性结肠炎、急性肠系膜缺血和慢性肠系膜缺血所占的比例分别为70.5%、16.1%和13.4%。B超、CTA及血管造影对缺血性肠病的阳性发现率、血管病变发现率差异具有统计学意义(P<0.05)。老年组与非老年组的临床症状差异无统计学意义,2组间在吸烟(P<0.01)、风湿性心脏病(P=0.046)、真性红细胞增多症(P=0.046)、原发性血小板增多症(P=0.021)、横结肠受累(P=0.021)、升结肠受累(P=0.006)、溃疡形成(P=0.034)、肠腔狭窄(P=0.021)等方面差异有统计学意义。结论缺血性肠病中以缺血性结肠炎最常见,好发于老年女性,临床表现无特异性。不同影像学检查对不同类型缺血性肠病诊断价值不同,怀疑缺血性结肠炎首选结肠镜,怀疑急性及慢性肠系膜缺血者则首选CTA及血管造影。吸烟、风湿性心脏病、真性红细胞增多症、原发性血小板增多症是中青年病人的易患因素。老年病人横结肠和升结肠受累更多见,更易出现肠道溃疡及狭窄,病情相对重,应给与积极治疗。 展开更多
关键词 缺血性肠病 急性肠系膜缺血 慢性肠系膜缺血 缺血性结肠炎 临床特点 老年人
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缺血预处理对大鼠移植肠冷缺血/再灌注损伤的保护作用 被引量:1
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作者 赵伟 车向明 +5 位作者 樊林 王曙逢 王光辉 张如愿 张立 张锋 《南方医科大学学报》 CAS CSCD 北大核心 2007年第11期1764-1766,共3页
目的探讨缺血预处理(IP)对不同冷保存时间大鼠移植肠的保护作用。方法将80只SD大鼠随机分为2组:即非预处理组(0-L组)与预处理组(L组),每组分别再分为4小组,按冷缺血时间分为3(L3)、6(L6)、12(L12)及18(L18)组,每组10只。建立大鼠缺血预... 目的探讨缺血预处理(IP)对不同冷保存时间大鼠移植肠的保护作用。方法将80只SD大鼠随机分为2组:即非预处理组(0-L组)与预处理组(L组),每组分别再分为4小组,按冷缺血时间分为3(L3)、6(L6)、12(L12)及18(L18)组,每组10只。建立大鼠缺血预处理模型,将各组供肠冷保存相对应时间。供肠行原位移植后再灌注1h取材,对其进行组织学观察,并观测NF-κB的表达。结果相同冷缺血时间的预处理组损伤明显较非预处理组轻,表现为预处理组较非预处理组小肠绒毛排列整齐,肌层水肿较轻,Chiu氏评分升高。预处理组较非预处理组上皮细胞NF-κB的表达减弱(P<0.05)。结论缺血预处理对不同冷保存时间移植肠具有保护作用。 展开更多
关键词 小肠移植 冷保存 缺血再灌注损伤 缺血预处理 NF-κB
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