[Objectives] The research aimed to study the anti-inflammatory effects of volatile oil from Ocimum basilicum L. in Bozhou through the experimental animal model of inflammation.[Methods] Xylene-induced mouse ear swelli...[Objectives] The research aimed to study the anti-inflammatory effects of volatile oil from Ocimum basilicum L. in Bozhou through the experimental animal model of inflammation.[Methods] Xylene-induced mouse ear swelling model and carrageenan-induced mouse paw swelling model were used to compare the anti-inflammatory effects of volatile oil from O. basilicum L.[Results] The extremely high, high, medium, and low doses of volatile oil from O. basilicum L. had a certain inhibitory effect on the ear swelling of mice induced by xylene ( P <0.05), and the inhibitory effect of high-dose group on the ear swelling of mice was better. The swollen degree of the mice s toes in the different dose groups of volatile oil from O. basilicum L. was significantly lower ( P <0.05), and the high-dose and middle-dose groups had better inhibition.[Conclusions] The volatile oil from O. basilicum L. in Bozhou had a significant inhibitory effect on xylene-induced mouse ear swelling and carrageenan-induced mouse paw swelling. It proved and clarified the anti-inflammatory effects of volatile oil from O. basilicum L. in Bozhou.展开更多
China(Bozhou) Chinese MedicinalHerbs Transaction Centre is a state-levelmarket special for Chinese medicinal herbsratified by the State Administration ofChinese Medicinal Herbs,StateAdministration of Medicines,StateAd...China(Bozhou) Chinese MedicinalHerbs Transaction Centre is a state-levelmarket special for Chinese medicinal herbsratified by the State Administration ofChinese Medicinal Herbs,StateAdministration of Medicines,StateAdministration of Industry and Commerceand the Ministry of Public Health.It is展开更多
基金Supported by Natural Science Research Projects of Colleges and Universities in Anhui Province(KJ2019A1180,KJ2018A0884,KJ2017A772)
文摘[Objectives] The research aimed to study the anti-inflammatory effects of volatile oil from Ocimum basilicum L. in Bozhou through the experimental animal model of inflammation.[Methods] Xylene-induced mouse ear swelling model and carrageenan-induced mouse paw swelling model were used to compare the anti-inflammatory effects of volatile oil from O. basilicum L.[Results] The extremely high, high, medium, and low doses of volatile oil from O. basilicum L. had a certain inhibitory effect on the ear swelling of mice induced by xylene ( P <0.05), and the inhibitory effect of high-dose group on the ear swelling of mice was better. The swollen degree of the mice s toes in the different dose groups of volatile oil from O. basilicum L. was significantly lower ( P <0.05), and the high-dose and middle-dose groups had better inhibition.[Conclusions] The volatile oil from O. basilicum L. in Bozhou had a significant inhibitory effect on xylene-induced mouse ear swelling and carrageenan-induced mouse paw swelling. It proved and clarified the anti-inflammatory effects of volatile oil from O. basilicum L. in Bozhou.
文摘China(Bozhou) Chinese MedicinalHerbs Transaction Centre is a state-levelmarket special for Chinese medicinal herbsratified by the State Administration ofChinese Medicinal Herbs,StateAdministration of Medicines,StateAdministration of Industry and Commerceand the Ministry of Public Health.It is