Objective To investigate th e value of proton magnetic resonance spectroscopy ( 1H-MRS) on diagnosis a nd differential diagnosis of the intracranial diseases by the MRS results of 52 patients. Methods 12 patients ...Objective To investigate th e value of proton magnetic resonance spectroscopy ( 1H-MRS) on diagnosis a nd differential diagnosis of the intracranial diseases by the MRS results of 52 patients. Methods 12 patients with benign glioma, 16 patients with malignant glioma, 10 patients with meningioma, 8 patients with virus encephalitis, and 6 patients with cerebral infarction underwent MRS in th e lesion region. We measured the area within the spectra of N-acetyl-aspartate (NAA), creatine/phosphocreatine (Cr), choline compounds (Cho), and lactate (Lac ). Results The spectra of meningiomas were characterized by abs ence of NAA. The spectra of gliomas were characterized by the decrease of NAA an d Cr, but the increase of Cho. The ratio of Cho to Cr was 2.25±1.21 in benign g liomas, while the ratio of Cho to Cr was 4.65±2.21 in malignant gliomas. The sp ectra of virus encephalitis appeared the decrease of NAA and the normality of Cr , with the 1.25±0.21 ratio of Cho/Cr. The apparent Lac wave could be seen in al l cerebral infarctions. Conclusion The value of 1H-MRS plays a significant role in the diagnosis and differential diagnosis of gliomas, mening iomas, virus encephalitis, and cerebral infarctions.展开更多
This article is presenting data from a retrospective analysis of medical records and computed tomography (CT) scans of patients’ chests with coronavirus infection “COVID-19” who applied to the diagnostic center of ...This article is presenting data from a retrospective analysis of medical records and computed tomography (CT) scans of patients’ chests with coronavirus infection “COVID-19” who applied to the diagnostic center of URFA in Osh during the first wave of the pandemic in the Kyrgyz Republic, with a description of individual clinical cases and their differential diagnosis. Chest computed tomography is one of the main methods in visual diagnosis of pneumonia in COVID-19 in hospitalized patients, which allows determining signs, symptoms for effective treatment.展开更多
目的探讨颅脑磁共振成像在帕金森病(Parkinson's disease,PD)与血管性帕金森综合征(vascular Parkinson syndrome,VP)鉴别诊断中的价值。方法选取42例确诊PD和46例确诊VP患者为受试对象,分别纳入PD组和VP组;将同期入院体检的50例健...目的探讨颅脑磁共振成像在帕金森病(Parkinson's disease,PD)与血管性帕金森综合征(vascular Parkinson syndrome,VP)鉴别诊断中的价值。方法选取42例确诊PD和46例确诊VP患者为受试对象,分别纳入PD组和VP组;将同期入院体检的50例健康志愿者纳入对照组。所有受试者均接受颅脑MRI检查。记录三组患者黑质致密带(substantia nigra zona compacta,SNc)宽度(width of pars compacta of substantia nigra,WPCSN)值、中脑直径及两者比值检测结果差异,分析PD患者及VP患者颅脑MRI影像特征。结果三组受试者中脑直径对比差异无统计学意义(P>0.05);PD组WPCSN值及WPCSN值/中脑直径检测结果均显著低于VP组和对照组(P<0.05);VP组和对照组上述两项指标检测结果对比差异无统计学意义(P>0.05)。PD组颅脑MRI影像示无特殊改变或颅脑正常老化改变者居多,VP组颅脑MRI影像多示颅内缺血性改变异常信号,主要区域为皮质下、侧脑室旁脑白质及基底节区等,小脑及脑干累及病例较少。结论颅脑MRI可在PD和VP鉴别诊断中发挥积极作用,具有较高的应用价值。展开更多
文摘Objective To investigate th e value of proton magnetic resonance spectroscopy ( 1H-MRS) on diagnosis a nd differential diagnosis of the intracranial diseases by the MRS results of 52 patients. Methods 12 patients with benign glioma, 16 patients with malignant glioma, 10 patients with meningioma, 8 patients with virus encephalitis, and 6 patients with cerebral infarction underwent MRS in th e lesion region. We measured the area within the spectra of N-acetyl-aspartate (NAA), creatine/phosphocreatine (Cr), choline compounds (Cho), and lactate (Lac ). Results The spectra of meningiomas were characterized by abs ence of NAA. The spectra of gliomas were characterized by the decrease of NAA an d Cr, but the increase of Cho. The ratio of Cho to Cr was 2.25±1.21 in benign g liomas, while the ratio of Cho to Cr was 4.65±2.21 in malignant gliomas. The sp ectra of virus encephalitis appeared the decrease of NAA and the normality of Cr , with the 1.25±0.21 ratio of Cho/Cr. The apparent Lac wave could be seen in al l cerebral infarctions. Conclusion The value of 1H-MRS plays a significant role in the diagnosis and differential diagnosis of gliomas, mening iomas, virus encephalitis, and cerebral infarctions.
文摘This article is presenting data from a retrospective analysis of medical records and computed tomography (CT) scans of patients’ chests with coronavirus infection “COVID-19” who applied to the diagnostic center of URFA in Osh during the first wave of the pandemic in the Kyrgyz Republic, with a description of individual clinical cases and their differential diagnosis. Chest computed tomography is one of the main methods in visual diagnosis of pneumonia in COVID-19 in hospitalized patients, which allows determining signs, symptoms for effective treatment.
文摘目的探讨颅脑磁共振成像在帕金森病(Parkinson's disease,PD)与血管性帕金森综合征(vascular Parkinson syndrome,VP)鉴别诊断中的价值。方法选取42例确诊PD和46例确诊VP患者为受试对象,分别纳入PD组和VP组;将同期入院体检的50例健康志愿者纳入对照组。所有受试者均接受颅脑MRI检查。记录三组患者黑质致密带(substantia nigra zona compacta,SNc)宽度(width of pars compacta of substantia nigra,WPCSN)值、中脑直径及两者比值检测结果差异,分析PD患者及VP患者颅脑MRI影像特征。结果三组受试者中脑直径对比差异无统计学意义(P>0.05);PD组WPCSN值及WPCSN值/中脑直径检测结果均显著低于VP组和对照组(P<0.05);VP组和对照组上述两项指标检测结果对比差异无统计学意义(P>0.05)。PD组颅脑MRI影像示无特殊改变或颅脑正常老化改变者居多,VP组颅脑MRI影像多示颅内缺血性改变异常信号,主要区域为皮质下、侧脑室旁脑白质及基底节区等,小脑及脑干累及病例较少。结论颅脑MRI可在PD和VP鉴别诊断中发挥积极作用,具有较高的应用价值。
