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A Comparative Study of Ultrasound-Guided Microwave Ablation, Surgery and Rotational Adenomammectomy for Benign Breast Nodules 被引量:1
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作者 Mei Zhang Wei Xu Can Liu 《Yangtze Medicine》 2021年第4期287-294,共8页
<strong>Objective:</strong> To explore the clinical effects of conventional surgery, ultrasound-guided microwave ablation and rotational adenomammectomy on the prognosis of benign breast nodules. <stron... <strong>Objective:</strong> To explore the clinical effects of conventional surgery, ultrasound-guided microwave ablation and rotational adenomammectomy on the prognosis of benign breast nodules. <strong>Methods:</strong> 232 cases of patients with benign breast nodules confirmed by pathological examination who received surgical treatment in the breast surgery department of our hospital from December 2016 to December 2020 were included. According to the surgical methods, they were divided into microwave ablation group (n = 48), conventional surgery group (n = 105) and rotational adenomammectomy group (n = 79). The clinical parameters were compared and analyzed between the three groups, and the postoperative pain, residual tumor, breast beauty and complication rate of the patients were evaluated. <strong>Results:</strong> Operative time, intraoperative blood loss, healing time and postoperative pain in microwave ablation group were lower than those of rotational adenomammectomy group (P < 0.05) and those of conventional surgery group (P < 0.05). Besides, those in the rotational adenomammectomy group were lower than those in the conventional surgery group (P < 0.05). The residual tumor rates in microwave ablation group and rotational adenomammectomy group were 4.17% and 3.80%, respectively. And the difference was not statistically significant (P > 0.05). Both of them were lower than 6.66% in conventional surgery group, with statistically significant differences (P < 0.05). The effective rates of breast beauty were 91.67%, 82.28% and 68.58% in the microwave ablation group, the rotational adenomammectomy group and the conventional surgery group, respectively. And the difference between groups was statistically significant (P < 0.05). The rate of postoperative complications in microwave ablation group and rotational adenomammectomy group were 4.17% and 3.80% respectively, both of which were significantly lower than 6.66% in conventional surgery group (P < 0.05). <strong>Conclusion:</strong> Microwave ablation, rotational adenomammectomy and conventional surgery are effective for the treatment of benign breast tumors. Among them, microwave ablation is the best option with many advantages of shorter operative time, less intraoperative blood loss, more beautiful breast shape, less postoperative pain, a lower residual rate after surgery, and a lower complication rate. 展开更多
关键词 benign breast nodules Microwave Ablation Surgical Operation Rotational Adenomammectomy PROGNOSIS
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Tongue image feature correlation analysis in benign lung nodules and lung cancer
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作者 SHI Yulin LIU Jiayi +2 位作者 CHUN Yi LIU Lingshuang XU Jiatuo 《Digital Chinese Medicine》 CAS CSCD 2024年第2期120-128,共9页
Objective To analyze the differences in the correlation of tongue image indicators among patients with benign lung nodules and lung cancer.Methods From July 1;2020 to March 31;2022;clinical information of lung cancer ... Objective To analyze the differences in the correlation of tongue image indicators among patients with benign lung nodules and lung cancer.Methods From July 1;2020 to March 31;2022;clinical information of lung cancer patients and benign lung nodules patients was collected at the Oncology Department of Longhua Hos-pital Affiliated to Shanghai University of Traditional Chinese Medicine and the Physical Ex-amination Center of Shuguang Hospital Affiliated to Shanghai University of Traditional Chi-nese Medicine;respectively.We obtained tongue images from patients with benign lung nod-ules and lung cancer using the TFDA-1 digital tongue diagnosis instrument;and analyzed these images with the TDAS V2.0 software.The extracted indicators included color space pa-rameters in the Lab system for both the tongue body(TB)and tongue coating(TC)(TB/TC-L;TB/TC-a;and TB/TC-b);textural parameters[TB/TC-contrast(CON);TB/TC-angular second moment(ASM);TB/TC-entropy(ENT);and TB/TC-MEAN];as well as TC parameters(perAll and perPart).The bivariate correlation of TB and TC features was analyzed using Pearson’s or Spearman’s correlation analysis;and the overall correlation was analyzed using canonical correlation analysis(CCA).Results Samples from 307 patients with benign lung nodules and 276 lung cancer patients were included after excluding outliers and extreme values.Simple correlation analysis indi-cated that the correlation of TB-L with TC-L;TB-b with TC-b;and TB-b with perAll in lung cancer group was higher than that in benign nodules group.Moreover;the correlation of TB-a with TC-a;TB-a with perAll;and the texture parameters of the TB(TB-CON;TB-ASM;TB-ENT;and TB-MEAN)with the texture parameters of the TC(TC-CON;TC-ASM;TC-ENT;and TC-MEAN)in benign nodules group was higher than lung cancer group.CCA further demon-strated a strong correlation between the TB and TC parameters in lung cancer group;with the first and second pairs of typical variables in benign nodules and lung cancer groups indicat-ing correlation coefficients of 0.918 and 0.817(P<0.05);and 0.940 and 0.822(P<0.05);re-spectively.Conclusion Benign lung nodules and lung cancer patients exhibited differences in correla-tion in the L;a;and b values of the TB and TC;as well as the perAll value of the TC;and the texture parameters(TB/TC-CON;TB/TC-ASM;TB/TC-ENT;and TB/TC-MEAN)between the TB and TC.Additionally;there were differences in the overall correlation of the TB and TC be-tween the two groups.Objective tongue diagnosis indicators can effectively assist in the diag-nosis of benign lung nodules and lung cancer;thereby providing a scientific basis for the ear-ly detection;diagnosis;and treatment of lung cancer. 展开更多
关键词 benign lung nodules Lung cancer Tongue image Correlation analysis Differential diagnosis
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Percutaneous Removal of Benign Breast Lesions with an Ultrasound-guided Vacuum-assisted System:Influence Factors in the Hematoma Formation 被引量:15
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作者 Hui-ping Huo Wen-bo Wan +2 位作者 Zhi-li Wang Hong-fei Li Jun-lai Li 《Chinese Medical Sciences Journal》 CAS CSCD 2016年第1期31-36,共6页
Objective To explore the influence factors in hematoma formation after removing benign breast lesions with an ultrasound-guided vacuum-assisted system.Methods A total of 232 females with 312 benign breast masses recei... Objective To explore the influence factors in hematoma formation after removing benign breast lesions with an ultrasound-guided vacuum-assisted system.Methods A total of 232 females with 312 benign breast masses received excisional biopsy with ultrasoundguided vacuum-assisted system.The pathology of patients,results of hematoma development and outcome,influence factors for hematoma occurrence(nodule size,nodule location,number of nodule,breast shape,menstrual period,efficacy time of bandage,and application of hemostatic agents during the procedure) were recorded.Results Pathologic examination revealed fibroadenomas in 138 lesions,fibroadenosis in 127 lesions,intraductal papillomas in 39 lesions,inflammatory change in 4 lesions,retention cyst of the breast in 3 lesions,and benign phyllodes tumor in 1 lesion.Thirty hematomas were observed in patients(9.6%).Finally,97.0%hematomas were absorbed completely within 6 months follow-up.The incidence rates of hematoma were increased by 24.7%,10.0%,63.2%,13.9%in the nodule diameter larger or equal to 25 mm group,removal of larger or equal to two nodules once time from one patient group,menstrual period group,and larger and loose breast group,respectively(all P<0.05).However,the incidences were decreased by 60.6%in the bandage performed for 12-24 hours or beyond 24 hours group(P<0.05).The multiple logistic regression models revealed that nodule size(x^2=15.227,P<0.001),number of nodule(x^2=7.767,P=0.005),menstrual period(x^2=24.530,P<0.001),and breast shape(x^2=9.559,P=0.002) were independent risk factors associated with hematoma occurrence,but efficacy time of bandage was a protective factor associated with hematoma occurrence.Conclusion The occurrence of hematoma after the minimally invasive operation was associated with nodule size,number of nodule,menstrual period,breast shape,and efficacy time of bandage. 展开更多
关键词 benign breast lesion ultrasound-guided vacuum-assisted system HEMATOMA influence factor
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Expression and Clinical Significance of Vascular Endothelial Growth Factor in Benign and Malignant Tissues of Breast 被引量:4
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作者 徐卫国 刘阳 +3 位作者 王刚 宋纪宁 杨小青 王文雅 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2008年第4期290-293,共4页
Objective: To detect the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) count in breast benign affection, breast atypical hyperplasia and breast carcinoma in situ, and to cl... Objective: To detect the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) count in breast benign affection, breast atypical hyperplasia and breast carcinoma in situ, and to clarify the relationship between VEGF expression, MVD and the clinicopathological features of these diseases. Methods: The expression of VEGF and MVD count in 115 cases breast benign diseases (including 40 breast fibroid tumor, 40 breast cystic hyperplasia and 35 intraductal papilloma, 19 breast atypical hyperplasias and 32 breast carcinomas in situ were examined by immunohistochemistry staining (SP-method). Results: The positive rate of VEGF in breast benign diseases, breast atypical hyperplasia and breast carcinoma in situ were 21.74%(25/115), 31.58.% (6/19)and 53.13%(17/32) respectively. It was the lowest in breast benign affection group, and was the highest breast carcinoma in situ group. The expression of VEGF increased gradually in the three groups (P〈0.05). The MVD count of the three groups were 14.41 ± 2.59, 18.89± 4.47 and 21.13 ± 4.12 respectively, It was the lowest in breast benign affection group, and was the highest breast carcinoma in situ group. The MVD count of the three groups increased gradually (P〈0.05). In VEGF positive group, MVD count was 19.41 ±4.78; In VEGF negative group, MVD count was 14.91±3.15. The MVD count was higher in VEGF positive group than that in VEGF negative group (P〈0.05). Conclusion: The results of this study suggested that VEGF could promote microvessel growth in breast tumors. The occurrence and progression of breast cancer might be related with the expression of VEGF. 展开更多
关键词 breast benign disease breast atypical hyperplasia breast carcinoma in situ Vascular endothelial growthfactor(VEGF) Microvessel density (MVD)
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Perithyroidal hemorrhage caused by hydrodissection during radiofrequency ablation for benign thyroid nodules:Two case reports 被引量:3
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作者 Bo-Wen Zheng Tao Wu +2 位作者 Zhi-Cheng Yao Yan-Ping Ma Jie Ren 《World Journal of Clinical Cases》 SCIE 2022年第29期10755-10762,共8页
BACKGROUND Hydrodissection is a widely used technique during radiofrequency ablation(RFA)for benign thyroid nodules.Although it could effectively avoid thermal injury to the surrounding critical structures and achieve... BACKGROUND Hydrodissection is a widely used technique during radiofrequency ablation(RFA)for benign thyroid nodules.Although it could effectively avoid thermal injury to the surrounding critical structures and achieve complete treatment,routine operation of the remaining needle could cause perithyroidal hemorrhage.In this report,we present 2 cases of perithyroidal hemorrhage during RFA caused by a hydrodissection needle,which have not been reported before.CASE SUMMARY A 21-year-old female and a 45-year-old male were admitted for RFA for benign thyroid nodules.Considering that their nodules were adjacent to the recurrent laryngeal nerve,the needle used for hydrodissection was placed and remained between the dorsal capsule of the lateral lobe and the recurrent laryngeal nerve.During the procedure,active bleeding near the needle appeared on ultrasonography(US).Although moderate pressure was quickly applied to the neck for several minutes,contrast-enhanced US(CEUS)still showed an active hemorrhage.A radiofrequency electrode was placed at the bleeding point under the guidance of CEUS to stop the bleeding,and the procedure was finally confirmed to be successful by CEUS,without other complications.CONCLUSION Hydrodissection during RFA of benign thyroid nodules was associated with a risk of perithyroidal hemorrhage.The timely recognition of this acute hemorrhage could help in the timely control of the bleeding,and CEUS-guided ablation of the bleeding point could be useful. 展开更多
关键词 COMPLICATION HEMORRHAGE HYDRODISSECTION Radiofrequency ablation benign thyroid nodules Case report
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Cosmetology Incision in Treatment of Benign Tumor of Breast: A Report of 1000 Cases 被引量:1
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作者 Mingqiang Han Lixian Yang Shubo Chen 《International Journal of Clinical Medicine》 2015年第7期465-468,共4页
Objective: To explore the selection of the best incision for operative treatment of benign breast tumor. Methods: The clinical data of 1000 cases of benign breast tumor operated by cosmetology incision were retrospect... Objective: To explore the selection of the best incision for operative treatment of benign breast tumor. Methods: The clinical data of 1000 cases of benign breast tumor operated by cosmetology incision were retrospectively analyzed. Results: All patients underwent tumor resection and were satisfied with the incision. Conclusions: Benign breast tumor can be excised through cosmetology incision, and no obvious scar leaves behind, so it can satisfy the cosmetic requirement of many patients. 展开更多
关键词 benign breast TUMOR COSMETOLOGY INCISION CICATRIX
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Male Breast Nodules in Ouagadougou (Burkina Faso): Radiological and Histopathological Aspects
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作者 Nina-Astrid Nde Ouedraogo Madina Napon +5 位作者 Bénilde Ma Kambou Tiemtore Boubakar Ouattara Abel Bamouni Ousséini Diallo Claudine Lougue Sorgho Rabiou Cisse 《Open Journal of Radiology》 2018年第4期274-280,共7页
Objective: To describe the radiological and histological aspects of breast nodules among men in our practice setting. Methodology: This is a descriptive and retrospective study conducted from January 2014 to October 2... Objective: To describe the radiological and histological aspects of breast nodules among men in our practice setting. Methodology: This is a descriptive and retrospective study conducted from January 2014 to October 2017. The study included male patients with breast nodules classified ACR3, 4 or 5 after a mammographic and ultrasound scan. These lesions were explored through an ultrasound-guided breast microbiopsy. The following are the variables collected: age, family history of breast cancer, medical history, ACR classification, nodule size, and anatomopathologic diagnosis. Results: 13 breast nodules were explored among 13 male subjects. Mammography and breast ultrasound enabled to identify one ACR3 lesion, 10 ACR4 lesions and 2 ACR5 lesions. The average age was 56.53 ± 14.63 years and the average size of the nodules 28.91 ± 13.62 mm. As for histology, there were seven malignant tumors and six benign tumors. The average age of patients with malignancy was 61.45 ± 13.62 years. The malignant nodules average size was 29.45 ± 12.54 mm. Malignant tumors exclusively consisted of invasive breast carcinomas while Benign ones consisted of dystrophic and inflammatory lesions. Conclusion: Most often Breast lesions among men had an indeterminate appearance on imaging and were predominantly malignant in histopathology. 展开更多
关键词 breast Microbiopsy Cancer breast Male benign NODULE
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HPV positivity varies with technique and primer set, in formalin-fixed paraffin-embedded benign and malignant breast tissue from Malta
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作者 Roderick Mallia Jean-Paul Mangion +6 位作者 Christian Camenzuli Annalisse Cassar Paul Cacciottolo John Cauchi Joseph Borg Sarfraz Ali Pierre Schembri-Wismayer 《American Journal of Molecular Biology》 2011年第3期183-188,共6页
The role of human papillomavirus in breast cancer pathogenesis is an area of considerable debate following differing results from all over the world. This study analyzed paraffin embedded tissue from 19 patients with ... The role of human papillomavirus in breast cancer pathogenesis is an area of considerable debate following differing results from all over the world. This study analyzed paraffin embedded tissue from 19 patients with benign or malignant breast disease. Standard PCR with GP5+/6+ and FAP primers, proved negative in all cases. However, qRT-PCR using the SF10 primer set detected HPV DNA in 2 out of these samples. Whilst our data does not support a major role for HPV in the pathogenesis of breast disease in Malta, it definitely does not exclude it totally. This study also clearly shows that the method of analysis is one of the variables resulting in the range of differing results witnessed worldwide in this area of study. 展开更多
关键词 Human PAPILLOMAVIRUS (HPV) breast Cancer benign qRT-PCR.
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Difference in microvascular structure between benign and malignant pulmonary nodules and its relationship with CT enhancement
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作者 刘士远 杨春山 +7 位作者 李慎江 顾倩 肖湘生 冯云 李成洲 李惠民 李玉莉 刘会敏 《Journal of Medical Colleges of PLA(China)》 CAS 2006年第4期243-248,共6页
Objective: To investigate the enhancement basis and the mechanisms of solitary pulmonary nodules (SPNs) by comparing the differences in microvascular structure between benign and malignant lesions. Methods: Dynami... Objective: To investigate the enhancement basis and the mechanisms of solitary pulmonary nodules (SPNs) by comparing the differences in microvascular structure between benign and malignant lesions. Methods: Dynamic contrast-enhanced CT scan was performed on 53 patients with SPNs (diameter〈3 cm, 38 peripheral lung cancers, 5 hamartomas, 10 inflammatory lesions) using a Siemens Plus S or a Marconi MX8000 multi slices spiral CT scanner. The time-attenuation curves were interpreted. The microvascular density (MVD) and the continuity of the microvessels' basemental membrane in the dissected specimens were observed with the ABC (avldin-biotin complex) immuno-histochemical method in all patients. Results :The CT enhancement values of lung cancer (49.05± 16.08 HU) and inflammatory lesions (49.59±21.30 HU) were significantly higher than those of hamartoma (8.98±4.56 HU) t=7.48, P〈0.051 t=8.35, P〈0.05). But the enhancement of lung cancer was similar to that of inflammatory lesions (t=0.76, P±0. 05). The time attenuation curve of inflammatory lesions tended to increase faster and reached a higher peak compared to the lung cancer, and both of them maintained a high plateau after crossing. The hamartoma showed a slight increase in the time-attenuation curve and demonstrated a lowplateau curve. The MVD of SPNs was positively correlated with CT enhancement (r=0. 8051). The microvascular counts of peripheral lung cancer (48.45±10. 09) and inflammatory lesions (49. 60±19. 94) were significantly higher than those of hamartoma (8.70±7. 30) (t=11. 64, P〈0.001, t=6. 09, P〈0. 001 ), but no significant difference was found between lung cancer and inflammatory lesions (t= -0.26, P=0.799). There was no difference in the continuity of basement membrane between nodules with anen haneement less than 30 HU and those with an enhancement higher than 30HU (X^2=3. 13, P〉0.05 ). Conclusion: The microvascular counts mainly contribute to the enhancement value of SPNs. The basement membrane is not related to nodule enhancement, but it might influence the pattern of the time-attenuation curve. 展开更多
关键词 solitary pulmonary nodule benign MALIGNANT computed tomography enhancement mierovessel density capillary basement membrane
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Clinical study of preoperative fT4/fT3 quotient and thyroid function test in distinguishing benign from malignant thyroid nodules
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作者 Yue Zhao Ning Wang +6 位作者 Chun-Rong Liu Tong-Shuo Zhang Jing-Hao Huang Jia-Jia Sun Guang-Lei Zhou Ying-Nan Wang Feng-Yun Wu 《Journal of Hainan Medical University》 2018年第20期52-56,共5页
Objective:To analyze the clinical and pathological characteristics of thyroid nodules and to explore the related risk factors of malignant thyroid nodules.Methods: According to the criteria of inclusion and exclusion,... Objective:To analyze the clinical and pathological characteristics of thyroid nodules and to explore the related risk factors of malignant thyroid nodules.Methods: According to the criteria of inclusion and exclusion, a total of 283 patients with thyroid nodules during January 2015 and December 2017 were divided into benign group (benign nodule,n =172) and malignant group (malignant nodule,n = 111) based on postoperative histopathological results. The age, sex, serum thyroglobulin antibody (TgAb), thyroid peroxidase antibody (TPOAb), thyroid stimulating hormone (TSH), free thyroxine (fT4), free three iodine thyroxine (fT3) and fT4/ fT3 ratio were subjected to univariate analysis, and the risk factors of malignant thyroid nodule were screened by multivariate logistic regression analysis.Results:Univariate analysis showed that age, TgAb, fT4 (P < 0.05) and fT4/ fT3 quotient (P < 0.01) were significantly different between the two groups. The fT4/fT3 quotient is a risk factor of malignant nodules. Multivariate logistic regression analysis indicated that the risk factors of malignant thyroid nodule were age (0R: 0.934,95% CI:0.911-0.957), TgAb(0R: 2.069,95% CI: 1.008-4.247) and fT4 (0R: 1.206,95% CI: 1.038-1.401).Conclusion: The fT4/fT3 quotient has important diagnostic value in differentiating benign and malignant thyroid nodules. When fT4 / fT3 > 3, it increases the risk of malignancy. The age, TgAb and fT4 are independent risk factors for malignant thyroid nodule, which is of great value in distinguishing benign from malignant thyroid nodules. 展开更多
关键词 Thyroid NODULE benign MALIGNANT Risk factors Logistic regression analysis
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Evaluation of Diagnostic Value of Ultrasound and Magnetic Resonance Imaging for Malignant and Benign Breast Lesions
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作者 Yanni Zeng Hongwei Zhang +2 位作者 Jiuxia Zhang Yan Yu Liangjin Liu 《Proceedings of Anticancer Research》 2018年第5期1-4,共4页
Objectives:To investigate diagnostic value of ultrasound and magnetic resonance imaging(MRI)for malignant and benign breast lesions.Methods:Retrospective analysis of treatment data of 48 patients diagnosed with malign... Objectives:To investigate diagnostic value of ultrasound and magnetic resonance imaging(MRI)for malignant and benign breast lesions.Methods:Retrospective analysis of treatment data of 48 patients diagnosed with malignant and benign breast lesions in our hospital,collected from December 2017 to November 2018.A total number of 56 breast masses were examined by both ultrasound and MRI,and were compared with postoperative pathological biopsy results.Results:Postoperative pathological biopsy results showed that there were 26 and 30 malignant and benign lesions respectively.Comparison of MRI curve type of malignant and benign lesions showed statistical significance(P<0.05).By comparison with pathological biopsy results,specificity and sensitivity of ultrasound diagnosis were 83.33%(25/30)and 84.61%(22/26)respectively;specificity and sensitivity of MRI diagnosis were 96.66%(29/30)and 92.30%(24/26)respectively.Conclusions:Ultrasonographic examination of malignant and benign breast lesions is straight-forward,simple and inexpensive.Accuracy,specificity and sensitivity of MRI are significantly higher than ultrasound in examining malignant and benign breast lesions,this can reduce misdiagnosis. 展开更多
关键词 breast MALIGNANT LESIONS benign LESIONS ULTRASOUND MRI
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Radio-Histopathological Aspects of Breast Nodules in a Sub-Saharan African City (Ouagadougou, Burkina Faso)
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作者 Nina-Astrid Nde Ouedraogo Bénilde Ma Kambou Tiemtore +7 位作者 Yobi Alexis Sawadogo Boubakar Ouattara Prosper David Lamien Madina Napon Ousséini Diallo Abel Bamouni Claudine Lougue Sorgho Rabiou Cisse 《Open Journal of Medical Imaging》 2018年第3期89-96,共8页
Objective: To determine the diagnostic contribution of breast microbiopsy percutaneously under ultrasound guidance. Methodology: Retrospective descriptive study conducted from January 2014 to October 2017. The include... Objective: To determine the diagnostic contribution of breast microbiopsy percutaneously under ultrasound guidance. Methodology: Retrospective descriptive study conducted from January 2014 to October 2017. The included patients had an ultrasound-guided breast microbiopsy after a mammographic and ultrasound scan. The variables collected were gender, age, nodule size, ACR classification and anatomopathologic diagnosis. Results: 347 nodules were explored in 313 patients. There were 300 women (95.85%) and 13 men (4.15%), a gender ratio of 23.07. The average age was 44.64 ± 14.18 years. The average size of the nodules was 30.33 ± 19.58 mm. There were 53.89% ACR4 grade nodules, 48% ACR5 nodules and 32.28% ACR3 nodules. 86.49% of ACR3 nodules were benign and 97.92% of ACR5 nodules were actually malignant. Malignant tumors accounted for 50.29% of the nodules and were dominated by invasive breast carcinomas in 98.26%. The average age of patients with malignant tumors was 49.15 ± 11.55 years. 16% of patients with malignancy were aged under 40 years old. Conclusion: The diagnostic yield was satisfactory and there was a good correlation between the rate of malignant and benign lesions and the positive predictive values of malignancy in the literature. 展开更多
关键词 breast Microbiopsy Ultrasound Guidance MAMMARY NODULE breast Cancer
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Pulmonary benign metastasizing leiomyoma: A case report and review of the literature 被引量:1
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作者 Hai-Yun Dai Shu-Liang Guo +1 位作者 Jian Shen Li Yang 《World Journal of Clinical Cases》 SCIE 2020年第14期3082-3089,共8页
BACKGROUND Pulmonary benign metastatic leiomyoma(PBML),which is very rare,is a type of benign metastatic leiomyoma(BML).Here,we report a case of PBML,finally diagnosed through multidisciplinary team(MDT)discussions,an... BACKGROUND Pulmonary benign metastatic leiomyoma(PBML),which is very rare,is a type of benign metastatic leiomyoma(BML).Here,we report a case of PBML,finally diagnosed through multidisciplinary team(MDT)discussions,and provide a literature review of the disease.CASE SUMMARY A 55-year old asymptomatic woman was found to have bilateral multiple lung nodules on a chest high-resolution computed tomography(HRCT)scan.Her medical history included total hysterectomy for uterine leiomyoma.The patient was diagnosed with PBML,on the basis of her clinical history,imaging manifestations,and computed tomography(CT)-guided percutaneous lung puncture biopsy,via MDT discussions.As the patient was asymptomatic,she received long-term monitoring without treatment.A follow-up of chest HRCT after 6 mo showed that the PBML lung nodules were stable and there was no progression.CONCLUSION For patients with a medical history of hysterectomy and uterine leiomyoma with lung nodules on chest CT,PBML should be considered during diagnosis based on the clinical history,imaging manifestations,CT-guided percutaneous lung puncture biopsy,and MDT discussions. 展开更多
关键词 Pulmonary benign metastatic leiomyoma Multidisciplinary team Computed tomography-guided percutaneous lung puncture biopsy Case report benign metastatic leiomyoma Lung nodule
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Differentiation of Benign and Malignant Solitary Pulmonary Nodule: Literature Review 被引量:3
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作者 Suresh Tripathi Xuqiu Zhen 《Advances in Lung Cancer》 2015年第2期17-24,共8页
The solitary pulmonary nodule (SPN) is frequently seen on chest radiographs and computed tomography (CT), usually the identification is accidental. The overall prevalence of malignancy is relatively low but identifica... The solitary pulmonary nodule (SPN) is frequently seen on chest radiographs and computed tomography (CT), usually the identification is accidental. The overall prevalence of malignancy is relatively low but identification of malignancy of nodule is of prime importance. There are different characters of nodules indicating malignancy, and also the exposure of person to risk factors increases the chances of malignancy of nodule. Chances of malignancy rise with increasing size, the irregular, lobulated border of the nodules is highly associated with higher probability of malignancy and nodules with pure ground grass appearance have higher probability of malignancy, irregularly marginated nodule displaying a corona radiata sign indicating neoplastic infiltration with distortion of neighbouring tissue is almost certainly a malignant nodule. Stippled, punctuate, and eccentric calcifications are suggestive of malignancy. There are 20% - 75% of chances of malignancy if nodule is appeared with ground-glass opacity. Malignant nodules have higher growth rate as compared with benign nodules, malignant nodules usually have doubling time (DT) of 30 - 400 days while DT of more than 450 days is sign of benignity whereas doubling time less than 30 days is usually acute infectious process. The presence of fat within nodule is sign of benignity. Increasing density of the nodule is suggestive of malignancy and requires shorter follow up. Besides the nodule evaluation the chances of malignancy can also be evaluated through the exposure of patient to risk factors like age, current and past smoking status and history of extra thoracic malignancy. The management depends upon various factors mainly three strategies are applied for management including careful observation of nodule, use of diagnostic techniques like CT FNA, PET, and broncoscopy and surgery. 展开更多
关键词 SOLITARY PULMONARY NODULE (SPN) benign PULMONARY NODULE MALIGNANT PULMONARY NODULE CT
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Complications Following Radiofrequency Ablation of Benign Thyroid Nodules: A Systematic Review 被引量:8
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作者 Jin-Fen Wang Tao Wu +6 位作者 Kun-Peng HU Wen Xu Bo-Wen Zheng Ge Tong Zhi-Cheng Yao Bo Liu Jie Ren 《Chinese Medical Journal》 SCIE CAS CSCD 2017年第11期1361-1370,共10页
Objective: This systematic review examined whether radiofrequency ablation (RFA) is a sate treatment modality for benign thyroid nodules (BTNs). Data Sources: PubMed, Embase, and the Cochrane Library database we... Objective: This systematic review examined whether radiofrequency ablation (RFA) is a sate treatment modality for benign thyroid nodules (BTNs). Data Sources: PubMed, Embase, and the Cochrane Library database were searched for articles that (a) targeted human beings and (b) had a study population with BTNs that were confirmed by fine-needle aspiration cytology and/or core needle biopsy. Study Selection: Thirty-two studies relating to 3409 patients were included in this systematic review. Results: Based on literatures, no deaths were associated with the procedure, serious complications were rare, and RFA appears to be a sale and well-tolerated treatment modality. However, a broad spectrum of complications offers insights into some undesirable complications, such as track needle seeding and Hornet syndrome. Conclusions: RFA appears to be a safe and well-tolerated treatment modality for BTNs. More research is needed to characterize the complications of RFA for thyroid nodules. 展开更多
关键词 benign nodules COMPLICATIONS Radioffequency Ablation THYROID
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Diagnostic value of artificial intelligence automatic detection systems for breast BI-RADS 4 nodules 被引量:7
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作者 Shu-Yi Lyu Yan Zhang +4 位作者 Mei-Wu Zhang Bai-Song Zhang Li-Bo Gao Lang-Tao Bai Jue Wang 《World Journal of Clinical Cases》 SCIE 2022年第2期518-527,共10页
BACKGROUND The incidence rate of breast cancer has exceeded that of lung cancer,and it has become the most malignant type of cancer in the world.BI-RADS 4 breast nodules have a wide range of malignant risks and are as... BACKGROUND The incidence rate of breast cancer has exceeded that of lung cancer,and it has become the most malignant type of cancer in the world.BI-RADS 4 breast nodules have a wide range of malignant risks and are associated with challenging clinical decision-making.AIM To explore the diagnostic value of artificial intelligence(AI)automatic detection systems for BI-RADS 4 breast nodules and to assess whether conventional ultrasound BI-RADS classification with AI automatic detection systems can reduce the probability of BI-RADS 4 biopsy.METHODS A total of 107 BI-RADS breast nodules confirmed by pathology were selected between June 2019 and July 2020 at Hwa Mei Hospital,University of Chinese Academy of Sciences.These nodules were classified by ultrasound doctors and the AI-SONIC breast system.The diagnostic values of conventional ultrasound,the AI automatic detection system,conventional ultrasound combined with the AI automatic detection system and adjusted BI-RADS classification diagnosis were statistically analyzed.RESULTS Among the 107 breast nodules,61 were benign(57.01%),and 46 were malignant(42.99%).The pathology results were considered the gold standard;furthermore,the sensitivity,specificity,accuracy,Youden index,and positive and negative predictive values were 84.78%,67.21%,74.77%,0.5199,66.10%and 85.42%for conventional ultrasound BI-RADS classification diagnosis,86.96%,75.41%,80.37%,0.6237,72.73%,and 88.46%for automatic AI detection,80.43%,90.16%,85.98%,0.7059,86.05%,and 85.94%for conventional ultrasound BI-RADS classification with automatic AI detection and 93.48%,67.21%,78.50%,0.6069,68.25%,and 93.18%for adjusted BI-RADS classification,respectively.The biopsy rate,cancer detection rate and malignancy risk were 100%,42.99%and 0%and 67.29%,61.11%,and 1.87%before and after BI-RADS adjustment,respectively.CONCLUSION Automatic AI detection has high accuracy in determining benign and malignant BI-RADS 4 breast nodules.Conventional ultrasound BI-RADS classification combined with AI automatic detection can reduce the biopsy rate of BI-RADS 4 breast nodules. 展开更多
关键词 BI-RADS classification Artificial intelligence breast nodules breast tumor
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Comparative FTIR spectroscopic analysis of human breast benign and malignant tissues 被引量:1
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作者 Yunxiang Ci Tiyu Gao +3 位作者 Jun Feng Zhenquan Guo Xiu Kan Jiangqiang Dong 《Chinese Science Bulletin》 SCIE EI CAS 1999年第9期804-808,共5页
Some remarkable FTIR spectral differences are observed and the differences at the molecular level are extracted between benign and malignant breast tissue samples. For the malignant tissue, the relative content of nuc... Some remarkable FTIR spectral differences are observed and the differences at the molecular level are extracted between benign and malignant breast tissue samples. For the malignant tissue, the relative content of nucleic acids is increased whereas the collagen is decreased. The proteins are phosphorylated and become more flexible and disordered. And these significant differences have important implications not only for probing the process of the breast lesion at the molecular level, but also for evaluating the histological types and grades of breast diseases. 展开更多
关键词 infrared spectroscopy breast benign and MALIGNANT tissues.
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FTIR assessment of the secondary structure of proteins in human breast benign and malignant tissues 被引量:1
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作者 Yunxiang Ci Tiyu Gao +2 位作者 Jianqiang Dong Xiu Kan Zhenquan Guo 《Chinese Science Bulletin》 SCIE EI CAS 1999年第24期2215-2221,共7页
The compositions of the secondary structures of protein in the human breast normal, hyperplasia, fibroadenoma and invasive ductal carcinoma tissues have been estimated from the Fourier self deconvolved spectra, the se... The compositions of the secondary structures of protein in the human breast normal, hyperplasia, fibroadenoma and invasive ductal carcinoma tissues have been estimated from the Fourier self deconvolved spectra, the second derivative spectra and the curve-fitting analysis of the amide I bands in their spectra. Some parameters of the secondary structures of proteins in these 4 types of tissues are significantly different and located in separate ranges. 展开更多
关键词 breast tumor tissue benign. malignant. FTIR protein SECONDARY structure composition.
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Monoexponential, biexponential and stretched-exponential models based diffusion weighted imaging: a comparative study in the differential diagnosis of benign and malignant breast lesions
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作者 靳雅楠 《China Medical Abstracts(Internal Medicine)》 2016年第3期143-,共1页
Objective To investgate the value of various parameters obtained from monoexponential,biexponential,and stretched exponential diffusion-weighted imaging models in the differential diagnosis of breast lesions.Methods A... Objective To investgate the value of various parameters obtained from monoexponential,biexponential,and stretched exponential diffusion-weighted imaging models in the differential diagnosis of breast lesions.Methods A retrospective study was performed in 54 patients with pathologically confirmed malignant tumors(n=30),benign lesions(n=34)and normal fibroglandular 展开更多
关键词 DDC biexponential and stretched-exponential models based diffusion weighted imaging Monoexponential a comparative study in the differential diagnosis of benign and malignant breast lesions
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Clinical Study on Treating Scrofula and Nodules of Breast by Blood-Letting Puncture
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作者 Feng Xinling(TCM Hospital of Wusu County,The Xinjiang Uyger Autonomous Region 833000) 《中国针灸》 CAS CSCD 北大核心 1995年第S2期302-302,共1页
ClinicalStudyonTreatingScrofulaandNodulesofBreastbyBlood-LettingPuncture¥FengXinling(TCMHospitalofWusuCounty... ClinicalStudyonTreatingScrofulaandNodulesofBreastbyBlood-LettingPuncture¥FengXinling(TCMHospitalofWusuCounty,TheXinjiangUyger... 展开更多
关键词 BLOOD breast CLINICAL Letting nodules PUNCTURE Scrofula Study TREATING and
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