Objective The aim of this study was to summarize and analyze the ultrasonographic and clinicopathologic features of benign brenner tumors of the ovary.Methods Forty-six patients with brenner tumors of the ovary were i...Objective The aim of this study was to summarize and analyze the ultrasonographic and clinicopathologic features of benign brenner tumors of the ovary.Methods Forty-six patients with brenner tumors of the ovary were included,and the imaging and pathologic features of the tumors were analyzed.Results Thirty-eight cases were unilateral,while eight cases were bilateral.The tumors were located only in the left ovary in 32 patients and in the right ovary in six patients.The median diameter of the tumors was 62 mm,and the diameter ranged from 15 to 270 mm.Vascular tumors were not observed.Most of the tumors(22/46)showed micro-perfusion,while 16 tumors showed no blood flow signal.Acoustic signal shadows after the cysts were observed in 26 tumors,accounting for 57%of all brenner tumors.Fourteen patients showed unilocular or multilocular tumors with no distinct characteristics on ultrasonography.Sixteen masses showed a multilocular solid structure,accompanied by calcification and a post-mass shadow;the solid structure showed mild-to-moderate vascularization on Doppler examination.Sixteen masses showed a pure solid structure,accompanied by calcification,resulting in an acoustic shadow behind the tumor;the solid structure showed mild-to-moderate vascularization on Doppler examination.Conclusion Some ultrasonographic features,including calcification with shadow,poor blood circulation of solid components,and mass localization,are helpful in the diagnosis of benign brenner tumors.展开更多
We report here an extremely rare case of proliferative Brenner tumor with borderline mucinous cystadenocarcinoma of the ovary, metastasizing to the pleura in a 75-year-old woman. Massive pleural effusion were present ...We report here an extremely rare case of proliferative Brenner tumor with borderline mucinous cystadenocarcinoma of the ovary, metastasizing to the pleura in a 75-year-old woman. Massive pleural effusion were present due to metastasis and pseudo-Meigs’ syndrome. The cytological findings from pleural effusion, ascites and tumor imprint were similar, suggesting mucus-producing malignant tumors. After receiving a thoracic drainage for pleural effusion, the patient underwent an exploratory laparotomy to remove the left-ovarian tumor. Histopathological examination revealed proliferative Brenner ovarian tumor with borderline mucinous cystadenocarcinoma, and immunohistochemical examinations for the tumors, even mucus-rich tumor cells were positive for CK 7 and negative for CK 20, suggesting the tumor arising from transitional cells, not from mucus-producing ovarian surface epithelial tumor cells. She underwent four courses of chemotherapy with paclitaxel and carboplatin. The patient showed no signs of recurrence 16 months after the surgery.展开更多
基金Supported by a grant from the Medical Research Project of the Sichuan Medical Association(No.s19332).
文摘Objective The aim of this study was to summarize and analyze the ultrasonographic and clinicopathologic features of benign brenner tumors of the ovary.Methods Forty-six patients with brenner tumors of the ovary were included,and the imaging and pathologic features of the tumors were analyzed.Results Thirty-eight cases were unilateral,while eight cases were bilateral.The tumors were located only in the left ovary in 32 patients and in the right ovary in six patients.The median diameter of the tumors was 62 mm,and the diameter ranged from 15 to 270 mm.Vascular tumors were not observed.Most of the tumors(22/46)showed micro-perfusion,while 16 tumors showed no blood flow signal.Acoustic signal shadows after the cysts were observed in 26 tumors,accounting for 57%of all brenner tumors.Fourteen patients showed unilocular or multilocular tumors with no distinct characteristics on ultrasonography.Sixteen masses showed a multilocular solid structure,accompanied by calcification and a post-mass shadow;the solid structure showed mild-to-moderate vascularization on Doppler examination.Sixteen masses showed a pure solid structure,accompanied by calcification,resulting in an acoustic shadow behind the tumor;the solid structure showed mild-to-moderate vascularization on Doppler examination.Conclusion Some ultrasonographic features,including calcification with shadow,poor blood circulation of solid components,and mass localization,are helpful in the diagnosis of benign brenner tumors.
文摘We report here an extremely rare case of proliferative Brenner tumor with borderline mucinous cystadenocarcinoma of the ovary, metastasizing to the pleura in a 75-year-old woman. Massive pleural effusion were present due to metastasis and pseudo-Meigs’ syndrome. The cytological findings from pleural effusion, ascites and tumor imprint were similar, suggesting mucus-producing malignant tumors. After receiving a thoracic drainage for pleural effusion, the patient underwent an exploratory laparotomy to remove the left-ovarian tumor. Histopathological examination revealed proliferative Brenner ovarian tumor with borderline mucinous cystadenocarcinoma, and immunohistochemical examinations for the tumors, even mucus-rich tumor cells were positive for CK 7 and negative for CK 20, suggesting the tumor arising from transitional cells, not from mucus-producing ovarian surface epithelial tumor cells. She underwent four courses of chemotherapy with paclitaxel and carboplatin. The patient showed no signs of recurrence 16 months after the surgery.
