AIM:To outline the appropriate diagnostic methods and therapeutic options for acquired bronchobiliary fistula(BBF).METHODS:Literature searches were performed in Medline,EMBASE,PHMC and LWW(January 1980August 2010)usin...AIM:To outline the appropriate diagnostic methods and therapeutic options for acquired bronchobiliary fistula(BBF).METHODS:Literature searches were performed in Medline,EMBASE,PHMC and LWW(January 1980August 2010)using the following keywords:biliobronchial fistula,bronchobiliary fistula,bronchobiliary fistula,biliarybronchial fistula,tracheobiliary fistula,hepatobronchial fistula,bronchopleural fistula,and biliptysis.Further articles were identified through crossreferencing.RESULTS:Sixtyeight cases were collected and reviewed.BBF secondary to tumors(32.3%,22/68),including primary tumors(19.1%,13/68)and hepatic metastases(13.2%,9/68),shared the largest proportion of all cases.Biliptysis was found in all patients,and other symptoms were respiratory symptoms,such as irritating cough,fever(36/68)and jaundice(20/68).Half of the patients were treated by lessinvasive methods such as endoscopic retrograde biliary drainage.Invasive approaches like surgery were used less frequently(41.7%,28/67).The outcome was good at the end of the followup period in 28 cases(range,2 wk to 72 mo),and the recovery rate was 87.7%(57/65).CONCLUSION:The clinical diagnosis of BBF can be established by sputum analysis.Careful assessment of this condition is needed before therapeutic procedure.Invasive approaches should be considered only when noninvasive methods failed.展开更多
BACKGROUND Congenital bronchobiliary fistula is a rare developmental abnormality with an abnormal fistula between the respiratory system and biliary tract. The aim of this report is to analyze and summarize the clinic...BACKGROUND Congenital bronchobiliary fistula is a rare developmental abnormality with an abnormal fistula between the respiratory system and biliary tract. The aim of this report is to analyze and summarize the clinical features and experience of diagnosing and treating congenital bronchobiliary fistula(CBBF) occurring in the neonatal period.CASE SUMMARY The onset of symptoms was 3 d after birth in our patient with progressive cyanosis and respiratory distress, and a large amount of green fluid was noticed in her respiratory secretion. We performed computed tomography(CT),fiberoptic bronchoscopy, and cholangiography to make a diagnosis, as well as fistulography with a bronchoscope for the first time. These examinations provided us with valuable images to make a correct diagnosis. The fistula was dissected and removed with excellent results. Surgical removal of the fistula was successful, and the baby recovered well and was discharged. She has been followed for 4 mo without any signs of discomfort.CONCLUSION The main symptom of CBBF is bile-like sputum. CT, bronchoscopy,fistulography, and intraoperative cholangiography can provide important evidence for diagnosis. Surgical resection of the fistula is the first choice of treatment.展开更多
BACKGROUND Bronchobiliary fistula(BBF)is a rare disease characterized by an abnormal connection between the biliary system and bronchi.Traditional causes of BBF include trauma and infections,and more recent causes inc...BACKGROUND Bronchobiliary fistula(BBF)is a rare disease characterized by an abnormal connection between the biliary system and bronchi.Traditional causes of BBF include trauma and infections,and more recent causes include malignancies and certain cancer treatments.Ramucirumab is an antivascular endothelial growth factor receptor 2 monoclonal antibody,currently used as a second-line treatment for gastric cancer.CASE SUMMARY A 43-year-old man visited our hospital with the complaint of jaundice.He was diagnosed with inoperable advanced gastric cancer owing to invasion of the hepatic hilum by the tumor.After percutaneous transhepatic biliary drainage(PTBD)and stent placement,capecitabine and oxaliplatin were administered as first-line palliative chemotherapy.The tumor progressed,and paclitaxel and ramucirumab were administered as second-line chemotherapy.However,on the first day of the second cycle,the patient suddenly developed dyspnea and pneumonia.BBF was diagnosed on the basis of the presence of bilious sputum and the results of computed tomography,and PTBD was repeated.CONCLUSION This is the first report of BBF after administration of the new antiangiogenic agent ramucirumab.展开更多
Bronchobiliary fistula(BBF) is one of the very rare disease.In this report,we described a BBF case.The case was diagnosed by endoscopic retrograde cholangio-pancreatography(ERCP) and percutaneous transhepatic cholangi...Bronchobiliary fistula(BBF) is one of the very rare disease.In this report,we described a BBF case.The case was diagnosed by endoscopic retrograde cholangio-pancreatography(ERCP) and percutaneous transhepatic cholangial drainage(PTCD) examinations,and treated properly.From the diagnosis of this BBF case,a patient with cough,biliptysis,fever and pain,should be considered for diagnosis of BBF.展开更多
文摘AIM:To outline the appropriate diagnostic methods and therapeutic options for acquired bronchobiliary fistula(BBF).METHODS:Literature searches were performed in Medline,EMBASE,PHMC and LWW(January 1980August 2010)using the following keywords:biliobronchial fistula,bronchobiliary fistula,bronchobiliary fistula,biliarybronchial fistula,tracheobiliary fistula,hepatobronchial fistula,bronchopleural fistula,and biliptysis.Further articles were identified through crossreferencing.RESULTS:Sixtyeight cases were collected and reviewed.BBF secondary to tumors(32.3%,22/68),including primary tumors(19.1%,13/68)and hepatic metastases(13.2%,9/68),shared the largest proportion of all cases.Biliptysis was found in all patients,and other symptoms were respiratory symptoms,such as irritating cough,fever(36/68)and jaundice(20/68).Half of the patients were treated by lessinvasive methods such as endoscopic retrograde biliary drainage.Invasive approaches like surgery were used less frequently(41.7%,28/67).The outcome was good at the end of the followup period in 28 cases(range,2 wk to 72 mo),and the recovery rate was 87.7%(57/65).CONCLUSION:The clinical diagnosis of BBF can be established by sputum analysis.Careful assessment of this condition is needed before therapeutic procedure.Invasive approaches should be considered only when noninvasive methods failed.
文摘BACKGROUND Congenital bronchobiliary fistula is a rare developmental abnormality with an abnormal fistula between the respiratory system and biliary tract. The aim of this report is to analyze and summarize the clinical features and experience of diagnosing and treating congenital bronchobiliary fistula(CBBF) occurring in the neonatal period.CASE SUMMARY The onset of symptoms was 3 d after birth in our patient with progressive cyanosis and respiratory distress, and a large amount of green fluid was noticed in her respiratory secretion. We performed computed tomography(CT),fiberoptic bronchoscopy, and cholangiography to make a diagnosis, as well as fistulography with a bronchoscope for the first time. These examinations provided us with valuable images to make a correct diagnosis. The fistula was dissected and removed with excellent results. Surgical removal of the fistula was successful, and the baby recovered well and was discharged. She has been followed for 4 mo without any signs of discomfort.CONCLUSION The main symptom of CBBF is bile-like sputum. CT, bronchoscopy,fistulography, and intraoperative cholangiography can provide important evidence for diagnosis. Surgical resection of the fistula is the first choice of treatment.
基金Supported by the National Research Foundation of Korea,funded by the Ministry of Science,ICT,and Future Planning,No.NRF-2015R1A5A2009070
文摘BACKGROUND Bronchobiliary fistula(BBF)is a rare disease characterized by an abnormal connection between the biliary system and bronchi.Traditional causes of BBF include trauma and infections,and more recent causes include malignancies and certain cancer treatments.Ramucirumab is an antivascular endothelial growth factor receptor 2 monoclonal antibody,currently used as a second-line treatment for gastric cancer.CASE SUMMARY A 43-year-old man visited our hospital with the complaint of jaundice.He was diagnosed with inoperable advanced gastric cancer owing to invasion of the hepatic hilum by the tumor.After percutaneous transhepatic biliary drainage(PTBD)and stent placement,capecitabine and oxaliplatin were administered as first-line palliative chemotherapy.The tumor progressed,and paclitaxel and ramucirumab were administered as second-line chemotherapy.However,on the first day of the second cycle,the patient suddenly developed dyspnea and pneumonia.BBF was diagnosed on the basis of the presence of bilious sputum and the results of computed tomography,and PTBD was repeated.CONCLUSION This is the first report of BBF after administration of the new antiangiogenic agent ramucirumab.
文摘Bronchobiliary fistula(BBF) is one of the very rare disease.In this report,we described a BBF case.The case was diagnosed by endoscopic retrograde cholangio-pancreatography(ERCP) and percutaneous transhepatic cholangial drainage(PTCD) examinations,and treated properly.From the diagnosis of this BBF case,a patient with cough,biliptysis,fever and pain,should be considered for diagnosis of BBF.
