Background: Artificial cervical disc replacement has become an option for cervical radiculopathy. Previous studies have evaluated the efficacy of this alternative without the scientific rigor of a concurrent control p...Background: Artificial cervical disc replacement has become an option for cervical radiculopathy. Previous studies have evaluated the efficacy of this alternative without the scientific rigor of a concurrent control population in oriental patients for long-term follow-up. Objective: Therefore, we asked whether the 1) clinical and 2) radiographic outcomes of Bryan cervical disc prosthesis were better than that of anterior cervical discectomy and fusion (ACDF) at single site, and whether the 3) occurrences of heterotopic ossifications (HOs) were associated to the function loss in the long-term follow-up. Methods:?A total of 120 patients with cervical disc disease were randomly assigned to two groups (Bryan or ACDF), and 60-month follow-up is available for all the 120 patients. Clinical outcomes were assessed using Odom’s criteria, visual analogue pain scale (VAS) and Neck Disability Index (NDI). Radiographs were measured to determine the radiographic outcomes and occurrences of heterotopic ossifications (HOs).?Results: The clinical outcomes are not significantly between the two groups (VAS, P = 0.7253;NDI, P = 0.5528). The radiographic outcome ofBryancervical disc prosthesis is better than that of ACDF group at the index level (P < 0.05). 36 (60%) patients ofBryangroup developed heterotopic ossification. But, there is not a significant association between HOs and the loss of movement at the replacement level. Conclusions: The Bryan artificial disc replacement compares favorably to ACDF for the treatment of patients with 1-level cervical disc disease. And theBryandisc may delay adjacent level degeneration by preserving preoperative kinematics at adjacent levels in oriental patients.展开更多
Objective To compare the clinical outcomes of Bryan disc replacement with anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylopathy. Methods Sixteen patients underwent Bryan cervicaldisc r...Objective To compare the clinical outcomes of Bryan disc replacement with anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylopathy. Methods Sixteen patients underwent Bryan cervicaldisc replacement (A group) ,and展开更多
目的:收集并分析SCI收录的关于Bryan颈椎间盘置换术与颈前路减压椎间融合术(anterior cervical discectomy and fusion,ACDF)术后疗效比较的文献,对Bryan颈椎间盘置换术和ACDF术后疗效进行系统评价。方法:检索Pubmed、Medline、Embase、...目的:收集并分析SCI收录的关于Bryan颈椎间盘置换术与颈前路减压椎间融合术(anterior cervical discectomy and fusion,ACDF)术后疗效比较的文献,对Bryan颈椎间盘置换术和ACDF术后疗效进行系统评价。方法:检索Pubmed、Medline、Embase、Ovid、Cochrane Library等数据库。入选文献均为临床研究;各研究的干预组(治疗组)术式为Bryan颈椎间盘置换术,对照组术式为ACDF;治疗组和对照组例数均不小于10;术后疗效评价包括颈部功能残障指数(neck disability index,NDI),相应节段运动范围(range of motion,ROM)等常见指标。结果:共4篇文献符合纳入标准。纳入人数共588人,干预组303例,对照组285例;术后2年内NDI合并权重均差(weighted mean difference,WMD)为-0.39(95%CI,-1.56～0.78),P>0.05。术后2年内相应颈椎节段运动范围(ROM)合并WMD值为8.95(95%CI,7.01～10.89),P<0.05。结论:Bryan间盘置换术在术后2年内保留颈椎节段活动方面优于ACDF,尚没有足够证据表明Bryan间盘置换术术后2年内NDI优于ACDF。展开更多
目的探讨颈椎前路减压植骨融合术(anterior cervical decompression and fusion,ACDF)与Bryan人工颈椎椎间盘置换术(artificial cervical disc replacement,ACDR)两种手术方式用于治疗脊髓型颈椎病及神经根型颈椎病的近期和远期疗效。...目的探讨颈椎前路减压植骨融合术(anterior cervical decompression and fusion,ACDF)与Bryan人工颈椎椎间盘置换术(artificial cervical disc replacement,ACDR)两种手术方式用于治疗脊髓型颈椎病及神经根型颈椎病的近期和远期疗效。方法系统分析我院2010年11月至2012年11月70例(70个节段)脊髓型或神经根型颈椎病患者病例资料,将70例(70个节段)脊髓型或神经根型颈椎病患者,通过随机数字表法随机分为ACDF组(35例)及Bryan组(35例)。通过分析术前及术后随访12个月的Odom's标准评分、活动度(range of motion,ROM)、日本骨科协会(Japanese orthopaedic association,JOA)、健康调查简表(the MOS item short from health survey,SF-36)及颈椎残障功能指数(neck disability index,NDI)观察指标的差异,同时对随访12个月的上述各项指标进行两组间比较,比较两者疗效,分析两种术式的优点及他们产生的问题。结果两种手术方式都能取得明确疗效,治疗后患者症状明显缓解(P<0.05),两种术式在创伤、出血量等方面差异性不显著(P>0.05);JOA评分及SF-36评分两者差异性不显著(P>0.05);而在12个月随访ROM评估及NDI比较有差异,Bryan组数据优于ACDF组,差异具有统计学意义(P<0.05);Bryan组在Odom's评分中因减压不彻底及异位骨化,有2例等级为差,ACDF组则为0例。结论 Bryan人工颈椎椎间盘置换术在减少颈椎临近节段退变上优于ACDF,短中期疗效优于ACDF,但Bryan人工颈椎椎间盘置换术同时存在减压不彻底及异位骨化等并发症,远期疗效不如ACDF。展开更多
目的:观察颈椎前路Hybrid术式治疗相邻双节段颈椎病的中长期临床疗效、影像结果及Bryan人工颈椎间盘置换节段的在体运动功能状态。方法:回顾性分析2010年7月~2013年12月于我院行颈椎前路相邻双节段Hybrid手术的患者,置换节段采用Bryan...目的:观察颈椎前路Hybrid术式治疗相邻双节段颈椎病的中长期临床疗效、影像结果及Bryan人工颈椎间盘置换节段的在体运动功能状态。方法:回顾性分析2010年7月~2013年12月于我院行颈椎前路相邻双节段Hybrid手术的患者,置换节段采用Bryan人工颈椎间盘,融合节段采用MC+椎间融合器,纳入末次随访时置换节段活动度(range of motion,ROM)>5°的43例患者,其中男性23例、女性20例,年龄49.1±5.6岁。脊髓型颈椎病26例,神经根型颈椎病6例,混合型颈椎病11例。术后随访84~119个月(95.43±8.21个月),采用日本骨科协会(Japanese Orthopaedic Association,JOA)颈椎评分、颈椎功能障碍指数(neck disability index,NDI)、疼痛视觉模拟评分(visual analogue scale,VAS)及Odom分级评估临床疗效。收集术前与末次随访时的颈椎中立侧位和动力位X线片,对比术前与末次随访时的颈椎整体ROM及曲度(C2-C7)、手术节段曲度、置换节段屈伸旋转中心(flexion and extension-center of rotation,FE-COR)及ROM、手术相邻节段ROM;末次随访时,观察邻近节段退变(adjacent segment degeneration,ASD)发生情况、融合节段融合情况,测量置换节段平移距离与关节突关节解剖参数:上关节突高度(height of superior articular process,HSAP)、关节突关节间隙倾斜度(orientation of zygapophyseal joint spaces,OZJS)和上关节突关节面长度(length of superior articular surface,LSAS),分析置换节段FE-COR与各项随访指标的相关性。结果 :末次随访时,JOA评分较术前显著性升高(9.26±3.38 vs 15.21±1.42,P<0.05),改善率为(80.23±13.80)%,NDI、颈痛VAS评分及双上肢痛VAS评分均较术前显著性降低(34.12±8.96 vs 7.21±4.32,P<0.05;5.77±2.28 vs 1.72±0.96,P<0.05;5.26±2.67 vs 1.14±0.83,P<0.05),改善率分别为(80.03±10.52)%、(69.85±13.44)%和(78.84±15.89)%。Odom分级优24例、良12例、可7例,优良率为83.72%。颈椎整体曲度、手术节段曲度分别由术前的14.76°±8.04°、4.78°±5.86°增加至末次随访的20.62°±9.06°、6.75°±4.65°(P<0.05),颈椎整体ROM、置换节段FE-COR及ROM、手术相邻节段ROM与术前比较均无统计学差异(P>0.05)。81个纳入研究的手术相邻节段(上位43个、下位38个)7个节段发生ASD(8.64%),分属于7例患者(7/43,16.28%),1例患者融合节段未获得骨性融合,但处于稳定状态(ROM<2°),其余患者融合节段均获得骨性融合,未发现与FE-COR横坐标(X)相关的随访指标(|r|<0.5或P>0.05),FE-COR纵坐标(Y)与同节段ROM、平移距离呈负相关(r=-0.674,P<0.05;r=-0.792,P<0.05),与HSAP呈正相关(r=0.754,P<0.05),与其他随访指标无显著相关性(|r|<0.5或P>0.05)。结论:颈椎前路相邻双节段Hybrid手术患者7年以上随访的临床与影像学结果满意,无证据显示融合节段对置换节段运动功能状态产生明显影响。展开更多
文摘Background: Artificial cervical disc replacement has become an option for cervical radiculopathy. Previous studies have evaluated the efficacy of this alternative without the scientific rigor of a concurrent control population in oriental patients for long-term follow-up. Objective: Therefore, we asked whether the 1) clinical and 2) radiographic outcomes of Bryan cervical disc prosthesis were better than that of anterior cervical discectomy and fusion (ACDF) at single site, and whether the 3) occurrences of heterotopic ossifications (HOs) were associated to the function loss in the long-term follow-up. Methods:?A total of 120 patients with cervical disc disease were randomly assigned to two groups (Bryan or ACDF), and 60-month follow-up is available for all the 120 patients. Clinical outcomes were assessed using Odom’s criteria, visual analogue pain scale (VAS) and Neck Disability Index (NDI). Radiographs were measured to determine the radiographic outcomes and occurrences of heterotopic ossifications (HOs).?Results: The clinical outcomes are not significantly between the two groups (VAS, P = 0.7253;NDI, P = 0.5528). The radiographic outcome ofBryancervical disc prosthesis is better than that of ACDF group at the index level (P < 0.05). 36 (60%) patients ofBryangroup developed heterotopic ossification. But, there is not a significant association between HOs and the loss of movement at the replacement level. Conclusions: The Bryan artificial disc replacement compares favorably to ACDF for the treatment of patients with 1-level cervical disc disease. And theBryandisc may delay adjacent level degeneration by preserving preoperative kinematics at adjacent levels in oriental patients.
文摘Objective To compare the clinical outcomes of Bryan disc replacement with anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylopathy. Methods Sixteen patients underwent Bryan cervicaldisc replacement (A group) ,and
文摘目的:收集并分析SCI收录的关于Bryan颈椎间盘置换术与颈前路减压椎间融合术(anterior cervical discectomy and fusion,ACDF)术后疗效比较的文献,对Bryan颈椎间盘置换术和ACDF术后疗效进行系统评价。方法:检索Pubmed、Medline、Embase、Ovid、Cochrane Library等数据库。入选文献均为临床研究;各研究的干预组(治疗组)术式为Bryan颈椎间盘置换术,对照组术式为ACDF;治疗组和对照组例数均不小于10;术后疗效评价包括颈部功能残障指数(neck disability index,NDI),相应节段运动范围(range of motion,ROM)等常见指标。结果:共4篇文献符合纳入标准。纳入人数共588人,干预组303例,对照组285例;术后2年内NDI合并权重均差(weighted mean difference,WMD)为-0.39(95%CI,-1.56～0.78),P>0.05。术后2年内相应颈椎节段运动范围(ROM)合并WMD值为8.95(95%CI,7.01～10.89),P<0.05。结论:Bryan间盘置换术在术后2年内保留颈椎节段活动方面优于ACDF,尚没有足够证据表明Bryan间盘置换术术后2年内NDI优于ACDF。
文摘目的探讨颈椎前路减压植骨融合术(anterior cervical decompression and fusion,ACDF)与Bryan人工颈椎椎间盘置换术(artificial cervical disc replacement,ACDR)两种手术方式用于治疗脊髓型颈椎病及神经根型颈椎病的近期和远期疗效。方法系统分析我院2010年11月至2012年11月70例(70个节段)脊髓型或神经根型颈椎病患者病例资料,将70例(70个节段)脊髓型或神经根型颈椎病患者,通过随机数字表法随机分为ACDF组(35例)及Bryan组(35例)。通过分析术前及术后随访12个月的Odom's标准评分、活动度(range of motion,ROM)、日本骨科协会(Japanese orthopaedic association,JOA)、健康调查简表(the MOS item short from health survey,SF-36)及颈椎残障功能指数(neck disability index,NDI)观察指标的差异,同时对随访12个月的上述各项指标进行两组间比较,比较两者疗效,分析两种术式的优点及他们产生的问题。结果两种手术方式都能取得明确疗效,治疗后患者症状明显缓解(P<0.05),两种术式在创伤、出血量等方面差异性不显著(P>0.05);JOA评分及SF-36评分两者差异性不显著(P>0.05);而在12个月随访ROM评估及NDI比较有差异,Bryan组数据优于ACDF组,差异具有统计学意义(P<0.05);Bryan组在Odom's评分中因减压不彻底及异位骨化,有2例等级为差,ACDF组则为0例。结论 Bryan人工颈椎椎间盘置换术在减少颈椎临近节段退变上优于ACDF,短中期疗效优于ACDF,但Bryan人工颈椎椎间盘置换术同时存在减压不彻底及异位骨化等并发症,远期疗效不如ACDF。
文摘目的:观察颈椎前路Hybrid术式治疗相邻双节段颈椎病的中长期临床疗效、影像结果及Bryan人工颈椎间盘置换节段的在体运动功能状态。方法:回顾性分析2010年7月~2013年12月于我院行颈椎前路相邻双节段Hybrid手术的患者,置换节段采用Bryan人工颈椎间盘,融合节段采用MC+椎间融合器,纳入末次随访时置换节段活动度(range of motion,ROM)>5°的43例患者,其中男性23例、女性20例,年龄49.1±5.6岁。脊髓型颈椎病26例,神经根型颈椎病6例,混合型颈椎病11例。术后随访84~119个月(95.43±8.21个月),采用日本骨科协会(Japanese Orthopaedic Association,JOA)颈椎评分、颈椎功能障碍指数(neck disability index,NDI)、疼痛视觉模拟评分(visual analogue scale,VAS)及Odom分级评估临床疗效。收集术前与末次随访时的颈椎中立侧位和动力位X线片,对比术前与末次随访时的颈椎整体ROM及曲度(C2-C7)、手术节段曲度、置换节段屈伸旋转中心(flexion and extension-center of rotation,FE-COR)及ROM、手术相邻节段ROM;末次随访时,观察邻近节段退变(adjacent segment degeneration,ASD)发生情况、融合节段融合情况,测量置换节段平移距离与关节突关节解剖参数:上关节突高度(height of superior articular process,HSAP)、关节突关节间隙倾斜度(orientation of zygapophyseal joint spaces,OZJS)和上关节突关节面长度(length of superior articular surface,LSAS),分析置换节段FE-COR与各项随访指标的相关性。结果 :末次随访时,JOA评分较术前显著性升高(9.26±3.38 vs 15.21±1.42,P<0.05),改善率为(80.23±13.80)%,NDI、颈痛VAS评分及双上肢痛VAS评分均较术前显著性降低(34.12±8.96 vs 7.21±4.32,P<0.05;5.77±2.28 vs 1.72±0.96,P<0.05;5.26±2.67 vs 1.14±0.83,P<0.05),改善率分别为(80.03±10.52)%、(69.85±13.44)%和(78.84±15.89)%。Odom分级优24例、良12例、可7例,优良率为83.72%。颈椎整体曲度、手术节段曲度分别由术前的14.76°±8.04°、4.78°±5.86°增加至末次随访的20.62°±9.06°、6.75°±4.65°(P<0.05),颈椎整体ROM、置换节段FE-COR及ROM、手术相邻节段ROM与术前比较均无统计学差异(P>0.05)。81个纳入研究的手术相邻节段(上位43个、下位38个)7个节段发生ASD(8.64%),分属于7例患者(7/43,16.28%),1例患者融合节段未获得骨性融合,但处于稳定状态(ROM<2°),其余患者融合节段均获得骨性融合,未发现与FE-COR横坐标(X)相关的随访指标(|r|<0.5或P>0.05),FE-COR纵坐标(Y)与同节段ROM、平移距离呈负相关(r=-0.674,P<0.05;r=-0.792,P<0.05),与HSAP呈正相关(r=0.754,P<0.05),与其他随访指标无显著相关性(|r|<0.5或P>0.05)。结论:颈椎前路相邻双节段Hybrid手术患者7年以上随访的临床与影像学结果满意,无证据显示融合节段对置换节段运动功能状态产生明显影响。
