According to the theory of Butts and Katz and the new radial dose distribution ofZhang et al., we have calculated inactivation cross sections for the heavy ion bombardmentof E. Coli B/r and Bs-1 which was in agreement...According to the theory of Butts and Katz and the new radial dose distribution ofZhang et al., we have calculated inactivation cross sections for the heavy ion bombardmentof E. Coli B/r and Bs-1 which was in agreement with the measurements of Schafer et al.,made with ions from O to U at energies from 1.5 to 19.5 MeV/u. The data display"thindown", and the decrease in cross section with an increase in stopping power isaccompanied by a decrease in energy of a bombarding ion. Following an earlier展开更多
Track theory rested on the foundation of the radial distribution of dose from δ rays as the central contribution of atomic physics to heavy ion radiobiology.Here,a new calculation of the radial distribution of dose i...Track theory rested on the foundation of the radial distribution of dose from δ rays as the central contribution of atomic physics to heavy ion radiobiology.Here,a new calculation of the radial distribution of dose is applied, in which the classical angular distribution of dose of delta rays and a logarithmic polynomial representation of the electron range-energy relation are used,to form the basis of the present thindown calculation.Calculations of inactivation cross sections for heavy ions in the track width regime displaying thindown for E.Colt B/r and Bs-1,and for Bacillus Subtilus are straightforward for these are 1-hit detectors,Calculations for V-79 hamster cells are more complex.They follow the original development of this model for eucaryotic cells,and make use of the cross sections calculated for hypothetical internal targets which are then asserted to be proportional to the measured cellular inactivation cross sections.The results are in reasonable agreement with experimental data.展开更多
基金Project supported by the U.S.Department of Energy and the National Natural Science Foundation of China.
文摘According to the theory of Butts and Katz and the new radial dose distribution ofZhang et al., we have calculated inactivation cross sections for the heavy ion bombardmentof E. Coli B/r and Bs-1 which was in agreement with the measurements of Schafer et al.,made with ions from O to U at energies from 1.5 to 19.5 MeV/u. The data display"thindown", and the decrease in cross section with an increase in stopping power isaccompanied by a decrease in energy of a bombarding ion. Following an earlier
文摘Track theory rested on the foundation of the radial distribution of dose from δ rays as the central contribution of atomic physics to heavy ion radiobiology.Here,a new calculation of the radial distribution of dose is applied, in which the classical angular distribution of dose of delta rays and a logarithmic polynomial representation of the electron range-energy relation are used,to form the basis of the present thindown calculation.Calculations of inactivation cross sections for heavy ions in the track width regime displaying thindown for E.Colt B/r and Bs-1,and for Bacillus Subtilus are straightforward for these are 1-hit detectors,Calculations for V-79 hamster cells are more complex.They follow the original development of this model for eucaryotic cells,and make use of the cross sections calculated for hypothetical internal targets which are then asserted to be proportional to the measured cellular inactivation cross sections.The results are in reasonable agreement with experimental data.
