This work analyzes the photometric data of the Oort spike comets C/2019 L3(ATLAS)and C/2019 O3(Palomar)obtained between 2016 and 2023 by the ATLAS network and the Belgian Olmen Observatory.The comets Palomar and ATLAS...This work analyzes the photometric data of the Oort spike comets C/2019 L3(ATLAS)and C/2019 O3(Palomar)obtained between 2016 and 2023 by the ATLAS network and the Belgian Olmen Observatory.The comets Palomar and ATLAS have a typical and unusually high activity level,respectively,based on the Afρparameter corrected to phase angle zero at perihelion.The absolute magnitude of comets ATLAS and Palomar in the o-band is 4.71±0.05 and 4.16±0.02 respectively.The cometary activity of comets ATLAS and Palomar probably began at r>13 au before perihelion and will end at r>14 au after perihelion,which means that they could remain active until the second half of 2026.The nucleus of comet ATLAS has a minimum radius of 7.9 km,and the nucleus of comet Palomar could be a little larger.The c-o colors of the comets ATLAS and Palomar are redder and bluer,respectively,at perihelion than the solar twin YBP 1194.These comets showed a bluish trend in the coma color with decreasing heliocentric distance.Comet Palomar probably had two outbursts after its perihelion,each releasing about 10^(8)kg of dust.The slopes of the photometric profile of the comae of these comets were between 1and 1.5,indicating a steady state during the observation campaign.展开更多
In recent times, lithium-ion batteries have been widely used owing to their high energy density, extended cycle lifespan, and minimal self-discharge rate. The design of high-speed rechargeable lithium-ion batteries fa...In recent times, lithium-ion batteries have been widely used owing to their high energy density, extended cycle lifespan, and minimal self-discharge rate. The design of high-speed rechargeable lithium-ion batteries faces a significant challenge owing to the need to increase average electric power during charging. This challenge results from the direct influence of the power level on the rate of chemical reactions occurring in the battery electrodes. In this study, the Taguchi optimization method was used to enhance the average electric power during the charging process of lithium-ion batteries. The Taguchi technique is a statistical strategy that facilitates the systematic and efficient evaluation of numerous experimental variables. The proposed method involved varying seven input factors, including positive electrode thickness, positive electrode material, positive electrode active material volume fraction, negative electrode active material volume fraction, separator thickness, positive current collector thickness, and negative current collector thickness. Three levels were assigned to each control factor to identify the optimal conditions and maximize the average electric power during charging. Moreover, a variance assessment analysis was conducted to validate the results obtained from the Taguchi analysis. The results revealed that the Taguchi method was an eff ective approach for optimizing the average electric power during the charging of lithium-ion batteries. This indicates that the positive electrode material, followed by the separator thickness and the negative electrode active material volume fraction, was key factors significantly infl uencing the average electric power during the charging of lithium-ion batteries response. The identification of optimal conditions resulted in the improved performance of lithium-ion batteries, extending their potential in various applications. Particularly, lithium-ion batteries with average electric power of 16 W and 17 W during charging were designed and simulated in the range of 0-12000 s using COMSOL Multiphysics software. This study efficiently employs the Taguchi optimization technique to develop lithium-ion batteries capable of storing a predetermined average electric power during the charging phase. Therefore, this method enables the battery to achieve complete charging within a specific timeframe tailored to a specificapplication. The implementation of this method can save costs, time, and materials compared with other alternative methods, such as the trial-and-error approach.展开更多
A new isochromanone,cladosporinisochromanone(1),accompanied by 15 known compounds(2–16)were obtained from secondary metabolites produced by marine-derived fungus Cladosporium sp.DLT-5.NMR and HRESIMS spectra elucidat...A new isochromanone,cladosporinisochromanone(1),accompanied by 15 known compounds(2–16)were obtained from secondary metabolites produced by marine-derived fungus Cladosporium sp.DLT-5.NMR and HRESIMS spectra elucidation determined the planar structure of 1.Subsequent electronic circular dichroism(ECD)experiment assigned the absolute configuration of 1.Compounds 1,2,4–6,and 10 displayed different degrees of neuroprotective activities on human neuroblastoma cells SH-SY5Y.Five compounds(1,3–5,and 13)emerged resistance to protein tyrosine phosphatase 1B(PTP1B),further kinetic analysis and molecular docking study indicated that the most potent compound 13(IC50value of 10.74±0.61μmol/L)was found as a noncompetitive inhibitor for PTP1B.Surface plasmon resonance(SPR)and molecular docking studies also demonstrated the interaction between compound 12 and Niemann-Pick C1 Like 1(NPC1L1),which has been identified as significant therapeutic target for hypercholesteremia.In addition,compounds 3,6,and 14 showed attractive inhibitory activity against the phytopathogenic fungi:Colletotrichum capsici.Therefore,library of Cladosporium metabolites is enriched and new active uses of known compounds are explored.展开更多
BACKGROUND The TGF-β/SMAD3 and VEGFR-1 signaling pathways play important roles in gastric cancer metastasis.SMAD3 phosphorylation is a crucial prognostic marker in gastric cancer.AIM To determine the prognostic value...BACKGROUND The TGF-β/SMAD3 and VEGFR-1 signaling pathways play important roles in gastric cancer metastasis.SMAD3 phosphorylation is a crucial prognostic marker in gastric cancer.AIM To determine the prognostic value and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer.METHODS This was a single-center observational study which enrolled 98 gastric cancer patients and 82 adjacent normal gastric tissues from patients aged 32-84 years(median age 65)between July 2006 and April 2007.Patients were followed up until death or the study ended(median follow-up duration of 28.5 mo).The samples were used to generate tissue microarrays(TMAs)for immunohistochemical(IHC)staining.The expressions of TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 in gastric cancer(GC)tumor tissue and normal tissue were measured by IHC staining using TMAs obtained from 98 GC patients.Prognosis and survival information of the patients was recorded by Outdo Biotech from May 2007 to July 2015.The relationship between TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 protein expression levels was analyzed using Pearson's correlation coefficient.The relationship between protein expression levels and clinicopathological parameters was analyzed using the Chi-squared test.A survival curve was generated using the Kaplan-Meier survival analysis.RESULTS TGFβ-1 and VEGFR-1 expression was significantly upregulated in gastric cancer tissue compared to adjacent noncancerous tissue.The positive expression of phosphorylated isoforms of Smad3 varied depending on the phosphorylation site[pSMAD3C(S423/425):51.0%and pSMAD3L(S204):31.6%].High expression of pSMAD-3L(S204)was significantly correlated with larger tumors(P=0.038)and later N stages(P=0.035).Additionally,high expression of VEGFR-1 was closely correlated with tumor size(P=0.015)and pathological grading(P=0.013).High expression of both pSMAD3L(S204)and VEGFR-1 was associated with unfavorable outcomes in terms of overall survival(OS).Multivariate analysis indicated that high expression of pSMAD3L(S204)and VEGFR-1 were independent risk factors for prognosis in GC patients.VEGFR-1 protein expression was correlated with TGF-β1(r=0.220,P=0.029),pSMAD3C(S423/425)(r=0.302,P=0.002),and pSMAD3L(S204)(r=0.201,P=0.047),respectively.Simultaneous overexpression of pSMAD3L(S204)and VEGFR-1 was associated with poor OS in gastric cancer patients.CONCLUSION Co-upregulation of pSMAD3L(S204)and VEGFR-1 can serve as a predictive marker for poor gastric cancer prognosis,and pSMAD3L(204)may be involved in enhanced gastric cancer metastasis in a VEGFR-1-dependent manner.展开更多
[Objectives] To screen and analyze germplasm resources of wild Coix lacryma-jobi L. with high content of coixin. [Methods] From the 150 kinds of collected wild C. lacryma-jobi L. germplasm resources, 24 kinds of excel...[Objectives] To screen and analyze germplasm resources of wild Coix lacryma-jobi L. with high content of coixin. [Methods] From the 150 kinds of collected wild C. lacryma-jobi L. germplasm resources, 24 kinds of excellent resources were screened and detected. Morphological statistics were carried out, and the content of coixin in the four organ of roots, stems, leaves and seeds were measured, and the approved cultivar white husk Liugu of C. lacryma-jobi L. was taking as the control. [Results] Among the organs of the plant of C. lacryma-jobi L., the roots had the highest content of coixin, so the roots of C. lacryma-jobi L. can be used as the medicinal parts of C. lacryma-jobi L. [Conclusions] The wild C. lacryma-jobi L.Y229, Y164, Y166, Y83, and Y84 stains had excellent yield, and their root coixin content was significantly higher than that of the control variety, so they can be used for cultivation as excellent germplasm, so as to obtain new variety(line) of C. lacryma-jobi L.with higher content of coixin.展开更多
[Objectives] To extract the flavonoids from leaves of Coix lacryma-jobi L. [Methods] Ethanol extraction method was adopted,spectrophotometry was used,and single factor experiment and orthogonal experiment were carried...[Objectives] To extract the flavonoids from leaves of Coix lacryma-jobi L. [Methods] Ethanol extraction method was adopted,spectrophotometry was used,and single factor experiment and orthogonal experiment were carried out to study the effects of ethanol percentage,extraction temperature,solid-to-liquid ratio and extraction time on the extraction of total flavonoids from leaves of C. lacryma-jobi L.[Results] The order of 4 factors influencing the extraction of flavonoids from leaves of C. lacryma-jobi L. was: solid-to-liquid ratio > extraction time > ethanol percentage > extraction temperature. When the extraction temperature was 70℃,the extraction time was 1. 5 h and the solid-liquid ratio was 1: 10,the ethanol percentage was 60%,the extraction effect was the best,extraction of flavonoids was 0. 107 5 mg/m L.[Conclusions] This study is expected to provide a theoretical basis for further development and utilization of C. lacryma-jobi L.展开更多
Levels of T1 (Thallium) in soil from 0 (control) to 50 μg/L through 0.2, 0.5, 1 and 2.5μg/L were directly and positively correlated to levels of T1 in plant tissue, the accumulation being maximum in roots, inter...Levels of T1 (Thallium) in soil from 0 (control) to 50 μg/L through 0.2, 0.5, 1 and 2.5μg/L were directly and positively correlated to levels of T1 in plant tissue, the accumulation being maximum in roots, intermediate in leaves and minimum in stems. Thallium, especially at higher concentrations, adversely affected photosynthesis (as judged based on chlorophyll fluorescence parameters), suggesting inhibition of photo-activation of PSII (Photosystems II), and also decreased the rate of photosynthesis, the rate of transpiration and stomatal conductivity drastically. Exposure to TI also increased the activity of CAT (Catalase) (except at 1 μg/L) and POD (Peroxidase) (except at 0.2 μg/L), suggesting that the antioxidant systems in Coix lacryma-jobi were the main contributors of CAT and SOD (Superoxide Dismutase) and that the tolerance of C. lacryma-jobi to T1 is mainly due to this induced antioxidant machinery.展开更多
[Objectives]The paper was to study the effects of different herbicides on weed control,agronomic characters and grain quality of Coix lacryma-jobi L.[Methods]Six commonly used herbicides were selected for the trial,in...[Objectives]The paper was to study the effects of different herbicides on weed control,agronomic characters and grain quality of Coix lacryma-jobi L.[Methods]Six commonly used herbicides were selected for the trial,including atrazine SC,butachlor SC,monosulfuron WP,MCPA-starane EC,clopyralid AS and tribenuron-methyl WP.[Results](i)Atrazine,butachlor and monosulfuron had no chemical injury to C.lacryma-jobi L.,while clopyralid caused slight chemical injury.(ii)The fresh weight control effects of atrazine,butachlor and monosulfuron on weeds increased first and then decreased.The initial control effect of MCPA-starane and clopyralid reached more than 90%;the control effect of monosulfuron increased gradually in the late stage,reaching 97%at 60 d post spraying,and the overall control effect was optimal.(iii)Compared with manual weeding,herbicides had no significant effect on plant height of C.lacryma-jobi L.However,compared with no weeding,other herbicides except tribenuron-methyl inhibited plant growth to a certain extent.Herbicides had different effects on main stem diameter,tiller number per plant and grain number per plant of C.lacryma-jobi L.(iv)Different herbicides had no significant effect on 100-grain weight,but had significant effect on yield.(v)Compared with manual weeding,atrazine,butachlor and clopyralid decreased the protein content of C.lacryma-jobi L.,and the use of atrazine,butachlor,monosulfuron,MCPA-starane and tribenuron-methyl decreased the fat content of C.lacryma-jobi L.;butachlor and MCPA-starane decreased the glycerol trioleate content of C.lacryma-jobi L.Compared with no weeding,chemical herbicides had no significant effect on the protein content,while atrazine decreased the fat content,and butachlor and MCPA-starane decreased the glycerol trioleate content of C.lacryma-jobi L.[Conclusions]The use of herbicides significantly increases crop yield compared with no weeding,but has an impact on agronomic characters and grain quality.展开更多
基金The ATLAS project is primarily funded to search for near-earth asteroids through NASA grants NN12AR55G,80NSSC18K0284,and 80NSSC18K1575funded by Kepler/K2 grant J1944/80NSSC19K0112 and HST GO-15889,and STFC grants ST/T000198/1 and ST/S006109/1。
文摘This work analyzes the photometric data of the Oort spike comets C/2019 L3(ATLAS)and C/2019 O3(Palomar)obtained between 2016 and 2023 by the ATLAS network and the Belgian Olmen Observatory.The comets Palomar and ATLAS have a typical and unusually high activity level,respectively,based on the Afρparameter corrected to phase angle zero at perihelion.The absolute magnitude of comets ATLAS and Palomar in the o-band is 4.71±0.05 and 4.16±0.02 respectively.The cometary activity of comets ATLAS and Palomar probably began at r>13 au before perihelion and will end at r>14 au after perihelion,which means that they could remain active until the second half of 2026.The nucleus of comet ATLAS has a minimum radius of 7.9 km,and the nucleus of comet Palomar could be a little larger.The c-o colors of the comets ATLAS and Palomar are redder and bluer,respectively,at perihelion than the solar twin YBP 1194.These comets showed a bluish trend in the coma color with decreasing heliocentric distance.Comet Palomar probably had two outbursts after its perihelion,each releasing about 10^(8)kg of dust.The slopes of the photometric profile of the comae of these comets were between 1and 1.5,indicating a steady state during the observation campaign.
文摘In recent times, lithium-ion batteries have been widely used owing to their high energy density, extended cycle lifespan, and minimal self-discharge rate. The design of high-speed rechargeable lithium-ion batteries faces a significant challenge owing to the need to increase average electric power during charging. This challenge results from the direct influence of the power level on the rate of chemical reactions occurring in the battery electrodes. In this study, the Taguchi optimization method was used to enhance the average electric power during the charging process of lithium-ion batteries. The Taguchi technique is a statistical strategy that facilitates the systematic and efficient evaluation of numerous experimental variables. The proposed method involved varying seven input factors, including positive electrode thickness, positive electrode material, positive electrode active material volume fraction, negative electrode active material volume fraction, separator thickness, positive current collector thickness, and negative current collector thickness. Three levels were assigned to each control factor to identify the optimal conditions and maximize the average electric power during charging. Moreover, a variance assessment analysis was conducted to validate the results obtained from the Taguchi analysis. The results revealed that the Taguchi method was an eff ective approach for optimizing the average electric power during the charging of lithium-ion batteries. This indicates that the positive electrode material, followed by the separator thickness and the negative electrode active material volume fraction, was key factors significantly infl uencing the average electric power during the charging of lithium-ion batteries response. The identification of optimal conditions resulted in the improved performance of lithium-ion batteries, extending their potential in various applications. Particularly, lithium-ion batteries with average electric power of 16 W and 17 W during charging were designed and simulated in the range of 0-12000 s using COMSOL Multiphysics software. This study efficiently employs the Taguchi optimization technique to develop lithium-ion batteries capable of storing a predetermined average electric power during the charging phase. Therefore, this method enables the battery to achieve complete charging within a specific timeframe tailored to a specificapplication. The implementation of this method can save costs, time, and materials compared with other alternative methods, such as the trial-and-error approach.
基金Supported by the China Agriculture Research System of MOF and MARA(CARS-21)the Financial Fund of the Ministry of Agriculture and Rural Affairs,China(No.NFZX2021)the National Natural Science Foundation of China(No.81973568)。
文摘A new isochromanone,cladosporinisochromanone(1),accompanied by 15 known compounds(2–16)were obtained from secondary metabolites produced by marine-derived fungus Cladosporium sp.DLT-5.NMR and HRESIMS spectra elucidation determined the planar structure of 1.Subsequent electronic circular dichroism(ECD)experiment assigned the absolute configuration of 1.Compounds 1,2,4–6,and 10 displayed different degrees of neuroprotective activities on human neuroblastoma cells SH-SY5Y.Five compounds(1,3–5,and 13)emerged resistance to protein tyrosine phosphatase 1B(PTP1B),further kinetic analysis and molecular docking study indicated that the most potent compound 13(IC50value of 10.74±0.61μmol/L)was found as a noncompetitive inhibitor for PTP1B.Surface plasmon resonance(SPR)and molecular docking studies also demonstrated the interaction between compound 12 and Niemann-Pick C1 Like 1(NPC1L1),which has been identified as significant therapeutic target for hypercholesteremia.In addition,compounds 3,6,and 14 showed attractive inhibitory activity against the phytopathogenic fungi:Colletotrichum capsici.Therefore,library of Cladosporium metabolites is enriched and new active uses of known compounds are explored.
基金Supported by National Nature Science Foundation of China,No.82060450,No.82360517,No.81460374,and No.31460304Nature Science Foundation of Jiangxi Province of China,No.20232BAB206086,No.20192BAB205072,No.20203BBGL73206,No.2017BCB23086,No.2017BAB205062,and No.20181BAB205050.
文摘BACKGROUND The TGF-β/SMAD3 and VEGFR-1 signaling pathways play important roles in gastric cancer metastasis.SMAD3 phosphorylation is a crucial prognostic marker in gastric cancer.AIM To determine the prognostic value and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer.METHODS This was a single-center observational study which enrolled 98 gastric cancer patients and 82 adjacent normal gastric tissues from patients aged 32-84 years(median age 65)between July 2006 and April 2007.Patients were followed up until death or the study ended(median follow-up duration of 28.5 mo).The samples were used to generate tissue microarrays(TMAs)for immunohistochemical(IHC)staining.The expressions of TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 in gastric cancer(GC)tumor tissue and normal tissue were measured by IHC staining using TMAs obtained from 98 GC patients.Prognosis and survival information of the patients was recorded by Outdo Biotech from May 2007 to July 2015.The relationship between TGF-β1,pSMAD3C(S423/425),pSMAD3L(S204),and VEGFR-1 protein expression levels was analyzed using Pearson's correlation coefficient.The relationship between protein expression levels and clinicopathological parameters was analyzed using the Chi-squared test.A survival curve was generated using the Kaplan-Meier survival analysis.RESULTS TGFβ-1 and VEGFR-1 expression was significantly upregulated in gastric cancer tissue compared to adjacent noncancerous tissue.The positive expression of phosphorylated isoforms of Smad3 varied depending on the phosphorylation site[pSMAD3C(S423/425):51.0%and pSMAD3L(S204):31.6%].High expression of pSMAD-3L(S204)was significantly correlated with larger tumors(P=0.038)and later N stages(P=0.035).Additionally,high expression of VEGFR-1 was closely correlated with tumor size(P=0.015)and pathological grading(P=0.013).High expression of both pSMAD3L(S204)and VEGFR-1 was associated with unfavorable outcomes in terms of overall survival(OS).Multivariate analysis indicated that high expression of pSMAD3L(S204)and VEGFR-1 were independent risk factors for prognosis in GC patients.VEGFR-1 protein expression was correlated with TGF-β1(r=0.220,P=0.029),pSMAD3C(S423/425)(r=0.302,P=0.002),and pSMAD3L(S204)(r=0.201,P=0.047),respectively.Simultaneous overexpression of pSMAD3L(S204)and VEGFR-1 was associated with poor OS in gastric cancer patients.CONCLUSION Co-upregulation of pSMAD3L(S204)and VEGFR-1 can serve as a predictive marker for poor gastric cancer prognosis,and pSMAD3L(204)may be involved in enhanced gastric cancer metastasis in a VEGFR-1-dependent manner.
基金Supported by Special Project of Guizhou Academy of Agricultural Sciences(Qian Nong Ke Yuan Yuan Zhuan Xiang[2014]010)Science and Technology Research Project for Social Development of Guizhou Province(Qian Ke He SY Zi[2015]3023-4)+1 种基金Special Project of Guizhou Academy of Agricultural Sciences(Qian Nong Ke Yuan Yuan Zhuan Xiang [2014]032)Project of Talent Work Leading Group Office of Guizhou Province(Qian Ren Ling Fa[2016]22)
文摘[Objectives] To screen and analyze germplasm resources of wild Coix lacryma-jobi L. with high content of coixin. [Methods] From the 150 kinds of collected wild C. lacryma-jobi L. germplasm resources, 24 kinds of excellent resources were screened and detected. Morphological statistics were carried out, and the content of coixin in the four organ of roots, stems, leaves and seeds were measured, and the approved cultivar white husk Liugu of C. lacryma-jobi L. was taking as the control. [Results] Among the organs of the plant of C. lacryma-jobi L., the roots had the highest content of coixin, so the roots of C. lacryma-jobi L. can be used as the medicinal parts of C. lacryma-jobi L. [Conclusions] The wild C. lacryma-jobi L.Y229, Y164, Y166, Y83, and Y84 stains had excellent yield, and their root coixin content was significantly higher than that of the control variety, so they can be used for cultivation as excellent germplasm, so as to obtain new variety(line) of C. lacryma-jobi L.with higher content of coixin.
基金Supported by Project of National Natural Science Foundation(81360684)Natural Science Foundation Project of Guangxi(2011GXNSFA018046)+3 种基金the 12th Five-Year TCM Key Discipline Chinese Medicine Chemistry Construction Program of State Administration of Traditional Chinese Medicine(Guo Zhong Yi Yao Ren Jiao Fa[2012]32)Key Discipline Chinese Medicine Chemistry Construction Program of Guangxi(Gui Jiao Ke Yan[2013]16)Program of Key Laboratory of Guangxi Universities on National Medicine in Youjiang River Basin(Gui Jiao Ke Yan[2014]14)Student’s Platform for Innovation and Entrepreneurship Training Program of Guangxi in 2015(201510599026)
文摘[Objectives] To extract the flavonoids from leaves of Coix lacryma-jobi L. [Methods] Ethanol extraction method was adopted,spectrophotometry was used,and single factor experiment and orthogonal experiment were carried out to study the effects of ethanol percentage,extraction temperature,solid-to-liquid ratio and extraction time on the extraction of total flavonoids from leaves of C. lacryma-jobi L.[Results] The order of 4 factors influencing the extraction of flavonoids from leaves of C. lacryma-jobi L. was: solid-to-liquid ratio > extraction time > ethanol percentage > extraction temperature. When the extraction temperature was 70℃,the extraction time was 1. 5 h and the solid-liquid ratio was 1: 10,the ethanol percentage was 60%,the extraction effect was the best,extraction of flavonoids was 0. 107 5 mg/m L.[Conclusions] This study is expected to provide a theoretical basis for further development and utilization of C. lacryma-jobi L.
文摘Levels of T1 (Thallium) in soil from 0 (control) to 50 μg/L through 0.2, 0.5, 1 and 2.5μg/L were directly and positively correlated to levels of T1 in plant tissue, the accumulation being maximum in roots, intermediate in leaves and minimum in stems. Thallium, especially at higher concentrations, adversely affected photosynthesis (as judged based on chlorophyll fluorescence parameters), suggesting inhibition of photo-activation of PSII (Photosystems II), and also decreased the rate of photosynthesis, the rate of transpiration and stomatal conductivity drastically. Exposure to TI also increased the activity of CAT (Catalase) (except at 1 μg/L) and POD (Peroxidase) (except at 0.2 μg/L), suggesting that the antioxidant systems in Coix lacryma-jobi were the main contributors of CAT and SOD (Superoxide Dismutase) and that the tolerance of C. lacryma-jobi to T1 is mainly due to this induced antioxidant machinery.
基金Key Technology R&D Program of Guizhou Province(QKHZC[2021]247)QKHZC[2018]2310。
文摘[Objectives]The paper was to study the effects of different herbicides on weed control,agronomic characters and grain quality of Coix lacryma-jobi L.[Methods]Six commonly used herbicides were selected for the trial,including atrazine SC,butachlor SC,monosulfuron WP,MCPA-starane EC,clopyralid AS and tribenuron-methyl WP.[Results](i)Atrazine,butachlor and monosulfuron had no chemical injury to C.lacryma-jobi L.,while clopyralid caused slight chemical injury.(ii)The fresh weight control effects of atrazine,butachlor and monosulfuron on weeds increased first and then decreased.The initial control effect of MCPA-starane and clopyralid reached more than 90%;the control effect of monosulfuron increased gradually in the late stage,reaching 97%at 60 d post spraying,and the overall control effect was optimal.(iii)Compared with manual weeding,herbicides had no significant effect on plant height of C.lacryma-jobi L.However,compared with no weeding,other herbicides except tribenuron-methyl inhibited plant growth to a certain extent.Herbicides had different effects on main stem diameter,tiller number per plant and grain number per plant of C.lacryma-jobi L.(iv)Different herbicides had no significant effect on 100-grain weight,but had significant effect on yield.(v)Compared with manual weeding,atrazine,butachlor and clopyralid decreased the protein content of C.lacryma-jobi L.,and the use of atrazine,butachlor,monosulfuron,MCPA-starane and tribenuron-methyl decreased the fat content of C.lacryma-jobi L.;butachlor and MCPA-starane decreased the glycerol trioleate content of C.lacryma-jobi L.Compared with no weeding,chemical herbicides had no significant effect on the protein content,while atrazine decreased the fat content,and butachlor and MCPA-starane decreased the glycerol trioleate content of C.lacryma-jobi L.[Conclusions]The use of herbicides significantly increases crop yield compared with no weeding,but has an impact on agronomic characters and grain quality.