Two new C-glucoside flavonoids, namely 8-C-b-D-(2-O-acetyl) glucofuranosyl apigenin and 3-O-acetylvitexin, were isolated from leaves of Crataegus pinnatifida Bge. var. major N. E. Br.. Their structures were elucidated...Two new C-glucoside flavonoids, namely 8-C-b-D-(2-O-acetyl) glucofuranosyl apigenin and 3-O-acetylvitexin, were isolated from leaves of Crataegus pinnatifida Bge. var. major N. E. Br.. Their structures were elucidated by the spectroscopic means and chemical evidence.展开更多
A new flavonoid, namely pinnatifine I (1), was isolated from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br.. Its structure was elucidated by spectroscopic analysis and chemical evidence.
Panax japonicus and its approximation varieties,such as Rhizoma Panacis Majoris and Panax japonicus C. A. Mey. var.major （Burk.） C.Y. Wu et K.M. Feng belong to Panax,which are less commonly used traditional Chinese ...Panax japonicus and its approximation varieties,such as Rhizoma Panacis Majoris and Panax japonicus C. A. Mey. var.major （Burk.） C.Y. Wu et K.M. Feng belong to Panax,which are less commonly used traditional Chinese medicine. Because of similar traits and effectiveness,they were always used as one type of medicine for a long time. Aiming at this phenomenon,the chemical composition and contents of P. japonicus and its approximation varieties from different area were compared in order to provide a chemical basis for clarifying the classification of the genus.展开更多
A new franchetine-type C19-diterpenoid alkaloid 3-hydroxyfranchetine 1 and a new aconitine-type C19-diterpenoid alkaloid atropurpursine 2 have been isolated from the roots of Aconitum hemsleyanium var. atropurpureum. ...A new franchetine-type C19-diterpenoid alkaloid 3-hydroxyfranchetine 1 and a new aconitine-type C19-diterpenoid alkaloid atropurpursine 2 have been isolated from the roots of Aconitum hemsleyanium var. atropurpureum. The structures of these new alkaloids were established on the basis of spectral data.展开更多
Two new tartrate derivative glucosides, coelovirin C (1) and D (2), were isolated from rhizomes of Coeloglossum viride ( L.) Hartm. var. bracteatum ( Willd.) Richter (Orchidaceae). Their structures were elucidated as ...Two new tartrate derivative glucosides, coelovirin C (1) and D (2), were isolated from rhizomes of Coeloglossum viride ( L.) Hartm. var. bracteatum ( Willd.) Richter (Orchidaceae). Their structures were elucidated as (2R, 3S)-2-b-D-glucopyranosyl-2-isobutyltartrate1-(4-b-D- glucopyranosyloxybenzyl) ester 1 and (2R, 3S)-2-b-D-glucopyranosyl-2-isobutyltartrate-4-(4-b-D- glucopyranosyloxybenzyl) ester 2 by means of chemical and spectroscopic methods.展开更多
AIM: To study influence of Valeriana officinalis var. latifolia(VOL) on expression of C Fos,C Jun after focal cerebral ischemia. METHODS: Inducing rat model of reversible middle cerebral artery occlusion(MCAO)using Ko...AIM: To study influence of Valeriana officinalis var. latifolia(VOL) on expression of C Fos,C Jun after focal cerebral ischemia. METHODS: Inducing rat model of reversible middle cerebral artery occlusion(MCAO)using Koizumi’s intraluminal suture occlusion method.48 male rats were divided into 5 groups randomly, pseudo operation group, MCAO group, saline control group,VOL group.2 hours after MCAO, we took gastric gavage with VOL and saline, 8 hour per time, and took out of brain to test C Fos,C Jun expression immunohistochemically at the 5th day after operation.RESULTS: There was no positive cell in each hippocampus zone of normal group;we observed C Fos, C Jun positive cells in each Hippocampus zone after MCAO;Density of C Fos,C Jun positive cells of VOL group were apparently lower than that of simple ischemia group. CONCLUSION: VOL can relieve histopathological lesions after cerebral ischemia and promote protection function of rat through inhibiting the expression of C Fos,C Jun expression.展开更多
An investigation of the alkaloids of Delphinium swinanense var. leptopogon resulted in the isolation and identification of two new C(19)-diterpene alkaloids named swinanine A and B, together with one known tatsiensine...An investigation of the alkaloids of Delphinium swinanense var. leptopogon resulted in the isolation and identification of two new C(19)-diterpene alkaloids named swinanine A and B, together with one known tatsiensine. The structures of the new alkaloids were established from spectraf evidence.展开更多
Three new lycoctonine-type C19-diterpenoid alkaloids, laxicymine 1, laxicymisine 2, and laxicyminine 3 have been isolated from the whole herb of Delphinium laxicymosum var. pilostachyum W.T. Wang. Their structures wer...Three new lycoctonine-type C19-diterpenoid alkaloids, laxicymine 1, laxicymisine 2, and laxicyminine 3 have been isolated from the whole herb of Delphinium laxicymosum var. pilostachyum W.T. Wang. Their structures were established by spectra data.展开更多
文摘Two new C-glucoside flavonoids, namely 8-C-b-D-(2-O-acetyl) glucofuranosyl apigenin and 3-O-acetylvitexin, were isolated from leaves of Crataegus pinnatifida Bge. var. major N. E. Br.. Their structures were elucidated by the spectroscopic means and chemical evidence.
文摘A new flavonoid, namely pinnatifine I (1), was isolated from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br.. Its structure was elucidated by spectroscopic analysis and chemical evidence.
基金Supported by the National Natural Foundation of China(30873383)~~
文摘Panax japonicus and its approximation varieties,such as Rhizoma Panacis Majoris and Panax japonicus C. A. Mey. var.major （Burk.） C.Y. Wu et K.M. Feng belong to Panax,which are less commonly used traditional Chinese medicine. Because of similar traits and effectiveness,they were always used as one type of medicine for a long time. Aiming at this phenomenon,the chemical composition and contents of P. japonicus and its approximation varieties from different area were compared in order to provide a chemical basis for clarifying the classification of the genus.
文摘A new franchetine-type C19-diterpenoid alkaloid 3-hydroxyfranchetine 1 and a new aconitine-type C19-diterpenoid alkaloid atropurpursine 2 have been isolated from the roots of Aconitum hemsleyanium var. atropurpureum. The structures of these new alkaloids were established on the basis of spectral data.
文摘Two new tartrate derivative glucosides, coelovirin C (1) and D (2), were isolated from rhizomes of Coeloglossum viride ( L.) Hartm. var. bracteatum ( Willd.) Richter (Orchidaceae). Their structures were elucidated as (2R, 3S)-2-b-D-glucopyranosyl-2-isobutyltartrate1-(4-b-D- glucopyranosyloxybenzyl) ester 1 and (2R, 3S)-2-b-D-glucopyranosyl-2-isobutyltartrate-4-(4-b-D- glucopyranosyloxybenzyl) ester 2 by means of chemical and spectroscopic methods.
文摘AIM: To study influence of Valeriana officinalis var. latifolia(VOL) on expression of C Fos,C Jun after focal cerebral ischemia. METHODS: Inducing rat model of reversible middle cerebral artery occlusion(MCAO)using Koizumi’s intraluminal suture occlusion method.48 male rats were divided into 5 groups randomly, pseudo operation group, MCAO group, saline control group,VOL group.2 hours after MCAO, we took gastric gavage with VOL and saline, 8 hour per time, and took out of brain to test C Fos,C Jun expression immunohistochemically at the 5th day after operation.RESULTS: There was no positive cell in each hippocampus zone of normal group;we observed C Fos, C Jun positive cells in each Hippocampus zone after MCAO;Density of C Fos,C Jun positive cells of VOL group were apparently lower than that of simple ischemia group. CONCLUSION: VOL can relieve histopathological lesions after cerebral ischemia and promote protection function of rat through inhibiting the expression of C Fos,C Jun expression.
文摘An investigation of the alkaloids of Delphinium swinanense var. leptopogon resulted in the isolation and identification of two new C(19)-diterpene alkaloids named swinanine A and B, together with one known tatsiensine. The structures of the new alkaloids were established from spectraf evidence.
文摘Three new lycoctonine-type C19-diterpenoid alkaloids, laxicymine 1, laxicymisine 2, and laxicyminine 3 have been isolated from the whole herb of Delphinium laxicymosum var. pilostachyum W.T. Wang. Their structures were established by spectra data.
