Microbiological diagnosis of chronic osteoarticular infections remains a major challenge,particularly when the clinical presentation is atypical and the pathogen is uncommon.In this unique case,Capnocytophaga canimors...Microbiological diagnosis of chronic osteoarticular infections remains a major challenge,particularly when the clinical presentation is atypical and the pathogen is uncommon.In this unique case,Capnocytophaga canimorsus,a microorganism belonging to the oral microbiota of some domestic animals,caused septic arthritis and multifocal osteomyelitis in the long bone of a 43-year-old immunocompetent man.The patient was treated with two-stage surgery and local and systemic antibiotic therapy,and had a successful recovery.C.canimorsus should be considered as a possible etiological agent in patients with osteoarticular pathology and a history of exposure to domestic animals.展开更多
目的鉴定1株脑梗死患者血液中分离的生痰二氧化碳嗜纤维菌。方法用血培养仪对脑梗死患者静脉血标本进行需氧和厌氧培养,分离培养阳性培养物,用生化鉴定卡进行生化鉴定,用质谱分析及16S r RNA基因序列分析进行补充鉴定,并用KB法进行药敏...目的鉴定1株脑梗死患者血液中分离的生痰二氧化碳嗜纤维菌。方法用血培养仪对脑梗死患者静脉血标本进行需氧和厌氧培养,分离培养阳性培养物,用生化鉴定卡进行生化鉴定,用质谱分析及16S r RNA基因序列分析进行补充鉴定,并用KB法进行药敏试验。结果该菌为革兰阴性细梭状杆菌,常规的方法无法鉴定至种。结合质谱分析及16S r RNA基因序列分析结果,鉴定为生痰二氧化碳嗜纤维菌。该菌对阿米卡星、环丙沙星、红霉素、阿奇霉素抑菌环均为6 mm,对其他药物的抑菌环较大。结论质谱分析和16S r RNA基因序列分析为常规方法无法鉴定至种的细菌鉴定提供了可靠依据,将本例细菌鉴定为生痰二氧化碳嗜纤维菌。展开更多
文摘Microbiological diagnosis of chronic osteoarticular infections remains a major challenge,particularly when the clinical presentation is atypical and the pathogen is uncommon.In this unique case,Capnocytophaga canimorsus,a microorganism belonging to the oral microbiota of some domestic animals,caused septic arthritis and multifocal osteomyelitis in the long bone of a 43-year-old immunocompetent man.The patient was treated with two-stage surgery and local and systemic antibiotic therapy,and had a successful recovery.C.canimorsus should be considered as a possible etiological agent in patients with osteoarticular pathology and a history of exposure to domestic animals.
文摘目的鉴定1株脑梗死患者血液中分离的生痰二氧化碳嗜纤维菌。方法用血培养仪对脑梗死患者静脉血标本进行需氧和厌氧培养,分离培养阳性培养物,用生化鉴定卡进行生化鉴定,用质谱分析及16S r RNA基因序列分析进行补充鉴定,并用KB法进行药敏试验。结果该菌为革兰阴性细梭状杆菌,常规的方法无法鉴定至种。结合质谱分析及16S r RNA基因序列分析结果,鉴定为生痰二氧化碳嗜纤维菌。该菌对阿米卡星、环丙沙星、红霉素、阿奇霉素抑菌环均为6 mm,对其他药物的抑菌环较大。结论质谱分析和16S r RNA基因序列分析为常规方法无法鉴定至种的细菌鉴定提供了可靠依据,将本例细菌鉴定为生痰二氧化碳嗜纤维菌。
