Assays of stress enzymes related to active oxygen species were performed by using an in vitro preparation from the liver of a monkey (Japanese Macaque). Ge-132, an organic germanium compound, viz. poly-trans-[(2-carbo...Assays of stress enzymes related to active oxygen species were performed by using an in vitro preparation from the liver of a monkey (Japanese Macaque). Ge-132, an organic germanium compound, viz. poly-trans-[(2-carboxyethyl) germasesquioxane] [(GeCH2CH2COOH)2O3]n, suppressed the activities of NADH-dependent oxidase and NADPH-dependent oxidase [NAD(P)H-OD] and xanthine oxidase (XOD) as superoxide-forming enzymes, while promoting the activities of superoxide dismutase (SOD) as a superoxide-scavenging enzyme and catalase (CAT) as an enzyme responsible for degradation of hydrogen peroxide (H2O2). The evidence suggests that the levels of active oxygen species such as and H2O2 would be reduced by Ge-132. The possible connection between Ge-132 and activities of stress enzymes is discussed on the basis of these results.展开更多
A Mn(II) picolilato complex Mn(2-C5H4NCOO)2(H2O)2?/2CH3CN 1 has been synthesized. Crystal of 1 is of monoclinic, space group C2/c with a = 25.6613(3), b = 8.6357(2), c = 16.8286(2) ? b = 122.835(1), V = 3133.47(9) ?, ...A Mn(II) picolilato complex Mn(2-C5H4NCOO)2(H2O)2?/2CH3CN 1 has been synthesized. Crystal of 1 is of monoclinic, space group C2/c with a = 25.6613(3), b = 8.6357(2), c = 16.8286(2) ? b = 122.835(1), V = 3133.47(9) ?, Mr=355.7, Dc = 1.508 g/cm3, F(000) = 1456, m = 0.874 cm1 and Z = 8. The final refinement gave R = 0.0362 and wR = 0.1096 for 2264 reflections (I > 2s(I)). The Mn(II) atom possesses distorted octahedral coordination geometry and the structural parameters around the Mn ion are close to those of other Mn analogues. Extensive hydrogen bonding interactions between carboxylate and H2O were observed making one-dimensional chains of the Mn monomers.展开更多
The title compound H2SiW12O40·(CH3)2NH was synthesized in mixed solvent of aqueous and acetonitrile, and its crystal structure had been determined using single crystal X ray diffraction. The crystal belongs to mo...The title compound H2SiW12O40·(CH3)2NH was synthesized in mixed solvent of aqueous and acetonitrile, and its crystal structure had been determined using single crystal X ray diffraction. The crystal belongs to monoclinic, space group C2/m, a=2.0654(4)nm, b=1.3306(3)nm, c=1.3194(3)nm, β=119.59(3)°, V=3.1531(11)nm3, Dc=3.606Mg·m-3, Z=2, R=0.0462, Rw=0.0836. The title compound comprises of a 2+ unit, a polyanion and a free (CH3)2NH molecule. The ESR spectrum of the title compound shows that charge transfer between organic groups and polyanion takes place under irradiation of the sunlight in solid state. The TG study of the title compound shows that it had four stages of the weight loss, and the increase of the decomposition temperature for the polyanion shows that the stability of the polyanion was enhanced due to the influence of Zn2+ ion. CCDC:175866.展开更多
A novel three dimensional fluorinated gallium phosphate has been hydrothermally synthesized by using diethylenetriamine as an organic structure directing agent. X ray single crystal structure analysis indicates this c...A novel three dimensional fluorinated gallium phosphate has been hydrothermally synthesized by using diethylenetriamine as an organic structure directing agent. X ray single crystal structure analysis indicates this compound crystallizes in the orthorhombic space group Pbca, a =1.605 6(7) nm, b = 1 011 4 (4) nm, c =1.854 6(5) nm, V =3.011 6(19) nm 3, Z =4. The three dimensional framework based on linkage of corner sharing polyhedron PO 4, GaO 4F and GaO 4F 2 delimit ten ring channels along b axis in which the triply protonated amines are located serving as charge compensating guests and supporters.展开更多
In this paper, a novel polymeric complex [MnNa（Salicylate）2（CH3OH）（H2O）]n·0.5nH2O was obtained and characterized by IR spectra, elemental analysis and single crystal X-ray diffraction. The titled complex is...In this paper, a novel polymeric complex [MnNa（Salicylate）2（CH3OH）（H2O）]n·0.5nH2O was obtained and characterized by IR spectra, elemental analysis and single crystal X-ray diffraction. The titled complex is crystallized in triclinic system, space group P1 with a=0.763 82（15） nm, b= 1.037 1（2） nm, c=1.290 9（3） nm, α= 103.59（3）°, β=104.65（3）°, γ=109.50（3）°, V=0.873 6（3） nm 3, Z=2, Dc=1.556 Mg/m 3, Mr=409.20, μ=0.823 mm -1, F（000）=418, R=0.0614, wR= 0.147 6. The activity in catalyzing the superoxygen anionic free radical dismutation was determinated.展开更多
A new molybdophosphate, (NH3CH2CH2NH3)2Mo5O15(HPO4)2 has been synthesized under hydrothermal conditions and structurally characterized by single crystal X ray diffractions. The compound crystallizes in the monoclinic,...A new molybdophosphate, (NH3CH2CH2NH3)2Mo5O15(HPO4)2 has been synthesized under hydrothermal conditions and structurally characterized by single crystal X ray diffractions. The compound crystallizes in the monoclinic, space group C2/c, a=1.7633(2)nm, b=1.00122(11) nm, c=1.37624(13)nm, β=96.974(5)°, V=2.4117(5)nm3, Z=4, Dc=2.853g·cm-3, μ(MoKα)=2.766mm-1, F(000)=1992. The structure contains the isolated polyanions of [Mo5O15(HPO4)2]4- units around which the portonated ethylenediamine ions are pos itioned. By hydrogen bond interactions the polyanions are interconnected to form a three dimensional network. Other characterizations by powder XRD, IR and thermal analysis are also described. CCDC: 206321.展开更多
文摘Assays of stress enzymes related to active oxygen species were performed by using an in vitro preparation from the liver of a monkey (Japanese Macaque). Ge-132, an organic germanium compound, viz. poly-trans-[(2-carboxyethyl) germasesquioxane] [(GeCH2CH2COOH)2O3]n, suppressed the activities of NADH-dependent oxidase and NADPH-dependent oxidase [NAD(P)H-OD] and xanthine oxidase (XOD) as superoxide-forming enzymes, while promoting the activities of superoxide dismutase (SOD) as a superoxide-scavenging enzyme and catalase (CAT) as an enzyme responsible for degradation of hydrogen peroxide (H2O2). The evidence suggests that the levels of active oxygen species such as and H2O2 would be reduced by Ge-132. The possible connection between Ge-132 and activities of stress enzymes is discussed on the basis of these results.
基金This work was supported by the State Key Basic Research and Development Plan (G1998010100) NNSFC (No. 29733090 and 29973047)
文摘A Mn(II) picolilato complex Mn(2-C5H4NCOO)2(H2O)2?/2CH3CN 1 has been synthesized. Crystal of 1 is of monoclinic, space group C2/c with a = 25.6613(3), b = 8.6357(2), c = 16.8286(2) ? b = 122.835(1), V = 3133.47(9) ?, Mr=355.7, Dc = 1.508 g/cm3, F(000) = 1456, m = 0.874 cm1 and Z = 8. The final refinement gave R = 0.0362 and wR = 0.1096 for 2264 reflections (I > 2s(I)). The Mn(II) atom possesses distorted octahedral coordination geometry and the structural parameters around the Mn ion are close to those of other Mn analogues. Extensive hydrogen bonding interactions between carboxylate and H2O were observed making one-dimensional chains of the Mn monomers.
文摘The title compound H2SiW12O40·(CH3)2NH was synthesized in mixed solvent of aqueous and acetonitrile, and its crystal structure had been determined using single crystal X ray diffraction. The crystal belongs to monoclinic, space group C2/m, a=2.0654(4)nm, b=1.3306(3)nm, c=1.3194(3)nm, β=119.59(3)°, V=3.1531(11)nm3, Dc=3.606Mg·m-3, Z=2, R=0.0462, Rw=0.0836. The title compound comprises of a 2+ unit, a polyanion and a free (CH3)2NH molecule. The ESR spectrum of the title compound shows that charge transfer between organic groups and polyanion takes place under irradiation of the sunlight in solid state. The TG study of the title compound shows that it had four stages of the weight loss, and the increase of the decomposition temperature for the polyanion shows that the stability of the polyanion was enhanced due to the influence of Zn2+ ion. CCDC:175866.
文摘A novel three dimensional fluorinated gallium phosphate has been hydrothermally synthesized by using diethylenetriamine as an organic structure directing agent. X ray single crystal structure analysis indicates this compound crystallizes in the orthorhombic space group Pbca, a =1.605 6(7) nm, b = 1 011 4 (4) nm, c =1.854 6(5) nm, V =3.011 6(19) nm 3, Z =4. The three dimensional framework based on linkage of corner sharing polyhedron PO 4, GaO 4F and GaO 4F 2 delimit ten ring channels along b axis in which the triply protonated amines are located serving as charge compensating guests and supporters.
文摘In this paper, a novel polymeric complex [MnNa（Salicylate）2（CH3OH）（H2O）]n·0.5nH2O was obtained and characterized by IR spectra, elemental analysis and single crystal X-ray diffraction. The titled complex is crystallized in triclinic system, space group P1 with a=0.763 82（15） nm, b= 1.037 1（2） nm, c=1.290 9（3） nm, α= 103.59（3）°, β=104.65（3）°, γ=109.50（3）°, V=0.873 6（3） nm 3, Z=2, Dc=1.556 Mg/m 3, Mr=409.20, μ=0.823 mm -1, F（000）=418, R=0.0614, wR= 0.147 6. The activity in catalyzing the superoxygen anionic free radical dismutation was determinated.
文摘A new molybdophosphate, (NH3CH2CH2NH3)2Mo5O15(HPO4)2 has been synthesized under hydrothermal conditions and structurally characterized by single crystal X ray diffractions. The compound crystallizes in the monoclinic, space group C2/c, a=1.7633(2)nm, b=1.00122(11) nm, c=1.37624(13)nm, β=96.974(5)°, V=2.4117(5)nm3, Z=4, Dc=2.853g·cm-3, μ(MoKα)=2.766mm-1, F(000)=1992. The structure contains the isolated polyanions of [Mo5O15(HPO4)2]4- units around which the portonated ethylenediamine ions are pos itioned. By hydrogen bond interactions the polyanions are interconnected to form a three dimensional network. Other characterizations by powder XRD, IR and thermal analysis are also described. CCDC: 206321.
