研究了基于CIM(City Information Modeling,城市信息模型)的城市规划辅助决策系统实现的关键技术,包括模型轻量化、场景优化与加速绘制及基于空间的规划分析算法技术;介绍了系统的总体架构,以及一种适应规划业务需求的数据库设计。在系...研究了基于CIM(City Information Modeling,城市信息模型)的城市规划辅助决策系统实现的关键技术,包括模型轻量化、场景优化与加速绘制及基于空间的规划分析算法技术;介绍了系统的总体架构,以及一种适应规划业务需求的数据库设计。在系统实现方面,介绍了场景组织浏览、景观视线分析、规划方案评审及规划辅助分析等模块的实现。实践表明,该系统在城市规划决策中具有较高的可行性和实用性。展开更多
城市信息模型(City Information Modeling,CIM)的兴起和广泛应用为城市高质量发展和智慧城市建设提供了重要支撑。本文面向智慧城市规建管需求,构建基于CIM的集“规划—投资—设计—建设—管理—运营—双碳—元宇宙”八大功能于一体的...城市信息模型(City Information Modeling,CIM)的兴起和广泛应用为城市高质量发展和智慧城市建设提供了重要支撑。本文面向智慧城市规建管需求,构建基于CIM的集“规划—投资—设计—建设—管理—运营—双碳—元宇宙”八大功能于一体的产城管理平台,实现线下物理城市与线上数字城市的深度融合,助力产城科学规划、高效建设和优质运营。在此基础上解析CIM平台的自我学习过程,提出数据迭代-模型迭代-服务迭代的多层次未来城市场景迭代框架,并分析其场景应用与反馈机制,助力产城全场景穿透,提高政府管理软实力。展开更多
Genetic improvement of drought resistance is one of the main breeding goals for common bean,so molecular markers must be identified to facilitate drought resistance breeding.In this study,we evaluated the proline,treh...Genetic improvement of drought resistance is one of the main breeding goals for common bean,so molecular markers must be identified to facilitate drought resistance breeding.In this study,we evaluated the proline,trehalose,raffinose,and stachyose contents of 210 common bean accessions under two watering conditions and found large variations in all four.The coefficients of variation ranged from 21.21%for proline content to 78.69%for stachyose content under well-watered conditions,and from 20.11%for proline content to 50.08%for trehalose content under drought stress.According to our genome-wide association analysis,32 quantitative trait loci were associated with drought resistance,seven of which overlapped with known loci.Four hotspot regions were identified at Pv01,Pv07 and Pv11.A set of candidate genes was identified,including genes encoding MYB,bZIP,bHLH,ERF,and protein kinases.Among these genes,Phvul.001G189400,Phvul.007G273000 and Phvul.008G270500 were annotated as bZIP,ERF and WRKY,respectively.These genes are reportedly involved in drought stress responses in Arabidopsis thaliana and were induced by drought stress in common bean.Significant SNPs in six candidate gene regions formed different haplotypes,and phenotypic analysis revealed significant differences among the haplotypes.These results provide new insight into the genetic basis of drought resistance in common bean and reveal candidate genes and superior natural variations that will be useful for improving common bean.展开更多
While endoscopic retrograde cholangiopancreatography(ERCP)remains the primary treatment modality for common bile duct stones(CBDS)or choledocho-lithiasis due to advancements in instruments,surgical intervention,known ...While endoscopic retrograde cholangiopancreatography(ERCP)remains the primary treatment modality for common bile duct stones(CBDS)or choledocho-lithiasis due to advancements in instruments,surgical intervention,known as common bile duct exploration(CBDE),is still necessary in cases of difficult CBDS,failed endoscopic treatment,or altered anatomy.Recent evidence also supports CBDE in patients requesting single-step cholecystectomy and bile duct stone removal with comparable outcomes.This review elucidates relevant clinical anatomy,selection indications,and outcomes to enhance surgical understanding.The selection between trans-cystic(TC)vs trans-choledochal(TD)approaches is described,along with stone removal techniques and ductal closure.Detailed surgical techniques and strategies for both the TC and TD approaches,including instrument selection,is also provided.Additionally,this review comprehensively addresses operation-specific complications such as bile leakage,stricture,and entrapment,and focuses on preventive measures and treatment strategies.This review aims to optimize the management of CBDS through laparoscopic CBDE,with the goal of improving patient outcomes and minimizing risks.展开更多
In this paper,we present a distal-scanning common path probe for optical coherence tomography(OCT)equipped with a hollow ultrasonic motor and a simple and specially designed beam-splitter.This novel probe proves to be...In this paper,we present a distal-scanning common path probe for optical coherence tomography(OCT)equipped with a hollow ultrasonic motor and a simple and specially designed beam-splitter.This novel probe proves to be able to effectively circumvent polarization and dispersion mismatch caused by fiber motion and is more robust to a variety of interfering factors during the imaging process,experimentally compared to a conventional noncommon path probe.Furthermore,our design counteracts the attenuation of backscattering with depth and the fall-off of the signal,resulting in a more balanced signal range and greater imaging depth.Spectral-domain OCT imaging of phantom and biological tissue is also demonstrated with a sensitivity of∼100dB and a lateral resolution of∼3μm.This low-cost probe offers simplified system configuration and excellent robustness,and is therefore particularly suitable for clinical diagnosis as one-off medical apparatus.展开更多
文摘研究了基于CIM(City Information Modeling,城市信息模型)的城市规划辅助决策系统实现的关键技术,包括模型轻量化、场景优化与加速绘制及基于空间的规划分析算法技术;介绍了系统的总体架构,以及一种适应规划业务需求的数据库设计。在系统实现方面,介绍了场景组织浏览、景观视线分析、规划方案评审及规划辅助分析等模块的实现。实践表明,该系统在城市规划决策中具有较高的可行性和实用性。
文摘城市信息模型(City Information Modeling,CIM)的兴起和广泛应用为城市高质量发展和智慧城市建设提供了重要支撑。本文面向智慧城市规建管需求,构建基于CIM的集“规划—投资—设计—建设—管理—运营—双碳—元宇宙”八大功能于一体的产城管理平台,实现线下物理城市与线上数字城市的深度融合,助力产城科学规划、高效建设和优质运营。在此基础上解析CIM平台的自我学习过程,提出数据迭代-模型迭代-服务迭代的多层次未来城市场景迭代框架,并分析其场景应用与反馈机制,助力产城全场景穿透,提高政府管理软实力。
基金supported by the National Key Research and Development Program of China(2019YFD1001300 and 2019YFD1001305)the Fundamental Research Funds for the Central Universities,China(SWUKQ22042)+1 种基金the China Agriculture Research System of MOF and MARA(CARS-08)the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences。
文摘Genetic improvement of drought resistance is one of the main breeding goals for common bean,so molecular markers must be identified to facilitate drought resistance breeding.In this study,we evaluated the proline,trehalose,raffinose,and stachyose contents of 210 common bean accessions under two watering conditions and found large variations in all four.The coefficients of variation ranged from 21.21%for proline content to 78.69%for stachyose content under well-watered conditions,and from 20.11%for proline content to 50.08%for trehalose content under drought stress.According to our genome-wide association analysis,32 quantitative trait loci were associated with drought resistance,seven of which overlapped with known loci.Four hotspot regions were identified at Pv01,Pv07 and Pv11.A set of candidate genes was identified,including genes encoding MYB,bZIP,bHLH,ERF,and protein kinases.Among these genes,Phvul.001G189400,Phvul.007G273000 and Phvul.008G270500 were annotated as bZIP,ERF and WRKY,respectively.These genes are reportedly involved in drought stress responses in Arabidopsis thaliana and were induced by drought stress in common bean.Significant SNPs in six candidate gene regions formed different haplotypes,and phenotypic analysis revealed significant differences among the haplotypes.These results provide new insight into the genetic basis of drought resistance in common bean and reveal candidate genes and superior natural variations that will be useful for improving common bean.
文摘While endoscopic retrograde cholangiopancreatography(ERCP)remains the primary treatment modality for common bile duct stones(CBDS)or choledocho-lithiasis due to advancements in instruments,surgical intervention,known as common bile duct exploration(CBDE),is still necessary in cases of difficult CBDS,failed endoscopic treatment,or altered anatomy.Recent evidence also supports CBDE in patients requesting single-step cholecystectomy and bile duct stone removal with comparable outcomes.This review elucidates relevant clinical anatomy,selection indications,and outcomes to enhance surgical understanding.The selection between trans-cystic(TC)vs trans-choledochal(TD)approaches is described,along with stone removal techniques and ductal closure.Detailed surgical techniques and strategies for both the TC and TD approaches,including instrument selection,is also provided.Additionally,this review comprehensively addresses operation-specific complications such as bile leakage,stricture,and entrapment,and focuses on preventive measures and treatment strategies.This review aims to optimize the management of CBDS through laparoscopic CBDE,with the goal of improving patient outcomes and minimizing risks.
基金supported in part by the National Natural Science Foundation of China under Grants 61975091,61905015,61575108,and 61505034by the Tsinghua Precision Medicine Foundation and“Bio-Brain+X”Advanced Imaging Instrument Development Seed Grant.
文摘In this paper,we present a distal-scanning common path probe for optical coherence tomography(OCT)equipped with a hollow ultrasonic motor and a simple and specially designed beam-splitter.This novel probe proves to be able to effectively circumvent polarization and dispersion mismatch caused by fiber motion and is more robust to a variety of interfering factors during the imaging process,experimentally compared to a conventional noncommon path probe.Furthermore,our design counteracts the attenuation of backscattering with depth and the fall-off of the signal,resulting in a more balanced signal range and greater imaging depth.Spectral-domain OCT imaging of phantom and biological tissue is also demonstrated with a sensitivity of∼100dB and a lateral resolution of∼3μm.This low-cost probe offers simplified system configuration and excellent robustness,and is therefore particularly suitable for clinical diagnosis as one-off medical apparatus.
