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A Contrastive Analysis of Conditionals in English and Moroccan Arabic: Potential problems when learning English conditionals by Moroccan EFL learners
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作者 Boubekri Abdelhakim Elasri Khalid 《宏观语言学》 2019年第2期110-135,共26页
Learning to handle hypothetical situations in a new language is always difficult(Catford,et al.,1974).This rule holds true for Moroccan Arabic(henceforth MA)speakers learning English because grammatical devices in the... Learning to handle hypothetical situations in a new language is always difficult(Catford,et al.,1974).This rule holds true for Moroccan Arabic(henceforth MA)speakers learning English because grammatical devices in the two languages differ in almost all equivalent situations.For instance,while English verb forms are used to indicate tense in conditional sentences,MA uses them to indicate aspect.Adopting the typology of conditional constructions suggested by Dancygier(1999)and Dancygier&Sweetser(2005),this study provides a contrastive analysis of conditionals in English and MA to predict the possible errors EFL/ESL learners are likely to make while learning English.The analysis shows that the main discrepancy between English conditionals and MA conditionals lies in the verb form used by the two systems.Accordingly,if EFL/ESL learners are influenced by verb form in their L1,they are likely to face some challenges while learning English conditionals.That is,they are likely to use the past tense in the protases of English predictive conditionals and generic conditionals since the perfective form of the verb is used in the protases of these two types in MA.Concerning the protases of English non-predictive conditionals,Moroccan EFL/ESL learners are likely to use either the past tense or the present tense since both the perfective and the imperfective forms of the verb are possible in the protases of MA non-predictive conditionals.However,due to the fact that the perfective form is the prototypical form in the protases of conditionals in MA,EFL/ESL learners are likely to use the past tense more often than the present tense.The analysis also shows that EFL/ESL learners tend to use the present tense in the apodoses of English conditionals since the prevalent form in the apodoses of MA conditionals is the imperfective. 展开更多
关键词 conditional constructions contrastive analysis EFL/ESL learners generic conditionals non-predictive conditionals predictive conditionals
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L2 Learning of English Conditionals: Online Versus Traditional Classroom Teaching
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作者 Abdulrahman Alzamil 《Sino-US English Teaching》 2022年第3期79-87,共9页
The issue of whether online teaching could replace traditional classroom(TC)teaching has attracted the attention of researchers in the applied linguistics literature.The current study attempted to shed light on this p... The issue of whether online teaching could replace traditional classroom(TC)teaching has attracted the attention of researchers in the applied linguistics literature.The current study attempted to shed light on this proposition by testing it on the difficult linguistic target of conditional if-clauses in English.The difficulty of these clauses stems from the fact that different tenses are used to express meanings that are sometimes not related to the tense used.The study recruited 49 participants,who were divided into two groups(23 in the online group,26 in the TC teaching group)and given a multiple-choice task containing 20 items.The study adopted a longitudinal research design(pretest and posttest).Each group was pretested before receiving just one two-hour treatment session.Then both groups were posttested.The results showed that both groups struggled with the second and third types of conditionals more than the zero and first types.The TC teaching group improved in the posttest in all types of conditionals.The online group improved in only two types of conditionals(zero and first).The TC teaching group outperformed the online group in the second and third conditionals.The findings indicate that classroom learning is superior to online learning and that,depending on their type,some conditionals in English are more difficult to learn than others. 展开更多
关键词 ONLINE traditional teaching L2 English conditionals ARABIC
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Programming with Conditionals: Epistemic Programming for Scientific Discovery
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作者 Jing\|de Cheng Department of Information and Computer Sciences, Saitama University Urawa, 338 8570, Japan 《Wuhan University Journal of Natural Sciences》 CAS 2001年第Z1期326-332,共7页
In order to provide scientists with a computational methodology and some computational tools to program their epistemic processes in scientific discovery, we are establishing a novel programming paradigm, named ‘Epis... In order to provide scientists with a computational methodology and some computational tools to program their epistemic processes in scientific discovery, we are establishing a novel programming paradigm, named ‘Epistemic Programming’, which regards conditionals as the subject of computing, takes primary epistemic operations as basic operations of computing, and regards epistemic processes as the subject of programming. This paper presents our fundamental observations and assumptions on scientific discovery processes and their automation, research problems on modeling, automating, and programming epistemic processes, and an outline of our research project of Epistemic Programming. 展开更多
关键词 scientific discovery conditional primary epistemic operations strong relevant logic epistemic programs temporal relevant logic
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A Brief Discussion on Conditionals
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作者 李利 《海外英语》 2011年第15期243-246,271,共5页
Conditionals are often divided into two categories: real conditional and unreal conditional. This paper will only discuss the former. As for the latter, it has been explained comparative exhaustively both in tradition... Conditionals are often divided into two categories: real conditional and unreal conditional. This paper will only discuss the former. As for the latter, it has been explained comparative exhaustively both in traditional grammar and contemporary grammar. In fact, real conditional is much more difficult than it is thought, because people have not described it as exhaustively as unreal conditional. 展开更多
关键词 CONDITIONAL CONDITION USAGE
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Combination treatment of inflammatory bowel disease:Present status and future perspectives 被引量:4
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作者 John K Triantafillidis Constantinos G Zografos +1 位作者 Manousos M Konstadoulakis Apostolos E Papalois 《World Journal of Gastroenterology》 SCIE CAS 2024年第15期2068-2080,共13页
The treatment of patients with inflammatory bowel disease(IBD),especially those with severe or refractory disease,represents an important challenge for the clinical gastroenterologist.It seems to be no exaggeration to... The treatment of patients with inflammatory bowel disease(IBD),especially those with severe or refractory disease,represents an important challenge for the clinical gastroenterologist.It seems to be no exaggeration to say that in these patients,not only the scientific background of the gastroenterologist is tested,but also the abundance of“gifts”that he should possess(insight,intuition,determ-ination,ability to take initiative,etc.)for the successful outcome of the treatment.In daily clinical practice,depending on the severity of the attack,IBD is treated with one or a combination of two or more pharmaceutical agents.These combin-ations include not only the first-line drugs(e.g.,mesalazine,corticosteroids,antibiotics,etc)but also second-and third-line drugs(immunosuppressants and biologic agents).It is a fact that despite the significant therapeutic advances there is still a significant percentage of patients who do not satisfactorily respond to the treatment applied.Therefore,a part of these patients are going to surgery.In recent years,several small-size clinical studies,reviews,and case reports have been published combining not only biological agents with other drugs(e.g.,immunosuppressants or corticosteroids)but also the combination of two biologi-cal agents simultaneously,especially in severe cases.In our opinion,it is at least a strange(and largely unexplained)fact that we often use combinations of drugs in a given patient although studies comparing the simultaneous administration of two or more drugs with monotherapy are very few.As mentioned above,there is a timid tendency in the literature to combine two biological agents in severe cases unresponsive to the applied treatment or patients with severe extraintestinal manifestations.The appropriate dosage,the duration of the administration,the suitable timing for checking the clinical and laboratory outcome,as well as the treatment side-effects,should be the subject of intense clinical research shortly.In this editorial,we attempt to summarize the existing data regarding the already applied combination therapies and to humbly formulate thoughts and suggestions for the future application of the combination treatment of biological agents in a well-defined category of patients.We suggest that the application of biomarkers and artificial intelligence could help in establishing new forms of treatment using the available modern drugs in patients with IBD resistant to treatment. 展开更多
关键词 Biologics for immune-mediated conditions Dual-targeted treatment Combination treatment Inflammatory bowel disease Crohn’s
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Assessing the Performance of CMIP6 Models in Simulating Droughts across Global Drylands 被引量:1
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作者 Xiaojing YU Lixia ZHANG +1 位作者 Tianjun ZHOU Jianghua ZHENG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第2期193-208,共16页
Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the curr... Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the current state-of-the-art Coupled Model Intercomparison Project phase 6(CMIP6) models remain unknown. Here, both the strengths and weaknesses of CMIP6 models in simulating droughts and corresponding hydrothermal conditions in drylands are assessed.While the general patterns of simulated meteorological elements in drylands resemble the observations, the annual precipitation is overestimated by ~33%(with a model spread of 2.3%–77.2%), along with an underestimation of potential evapotranspiration(PET) by ~32%(17.5%–47.2%). The water deficit condition, measured by the difference between precipitation and PET, is 50%(29.1%–71.7%) weaker than observations. The CMIP6 models show weaknesses in capturing the climate mean drought characteristics in drylands, particularly with the occurrence and duration largely underestimated in the hyperarid Afro-Asian areas. Nonetheless, the drought-associated meteorological anomalies, including reduced precipitation, warmer temperatures, higher evaporative demand, and increased water deficit conditions, are reasonably reproduced. The simulated magnitude of precipitation(water deficit) associated with dryland droughts is overestimated by 28%(24%) compared to observations. The observed increasing trends in drought fractional area,occurrence, and corresponding meteorological anomalies during 1980–2014 are reasonably reproduced. Still, the increase in drought characteristics, associated precipitation and water deficit are obviously underestimated after the late 1990s,especially for mild and moderate droughts, indicative of a weaker response of dryland drought changes to global warming in CMIP6 models. Our results suggest that it is imperative to employ bias correction approaches in drought-related studies over drylands by using CMIP6 outputs. 展开更多
关键词 DROUGHTS hydrothermal conditions DRYLANDS CMIP6 model evaluation
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Dynamics and genetic regulation of macronutrient concentrations during grain development in maize 被引量:1
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作者 Pengcheng Li Shuangyi Yin +7 位作者 Yunyun Wang Tianze Zhu Xinjie Zhu Minggang Ji Wenye Rui Houmiao Wang Chenwu Xu Zefeng Yang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第3期781-794,共14页
Nitrogen(N), phosphorus(P), and potassium(K) are essential macronutrients that are crucial not only for maize growth and development, but also for crop yield and quality. The genetic basis of macronutrient dynamics an... Nitrogen(N), phosphorus(P), and potassium(K) are essential macronutrients that are crucial not only for maize growth and development, but also for crop yield and quality. The genetic basis of macronutrient dynamics and accumulation during grain filling in maize remains largely unknown. In this study, we evaluated grain N, P, and K concentrations in 206 recombinant inbred lines generated from a cross of DH1M and T877 at six time points after pollination. We then calculated conditional phenotypic values at different time intervals to explore the dynamic characteristics of the N, P, and K concentrations. Abundant phenotypic variations were observed in the concentrations and net changes of these nutrients. Unconditional quantitative trait locus(QTL) mapping revealed 41 non-redundant QTLs, including 17, 16, and 14 for the N, P, and K concentrations, respectively. Conditional QTL mapping uncovered 39 non-redundant QTLs related to net changes in the N, P, and K concentrations. By combining QTL, gene expression, co-expression analysis, and comparative genomic data, we identified 44, 36, and 44 candidate genes for the N, P, and K concentrations, respectively, including GRMZM2G371058 encoding a Doftype zinc finger DNA-binding family protein, which was associated with the N concentration, and GRMZM2G113967encoding a CBL-interacting protein kinase, which was related to the K concentration. The results deepen our understanding of the genetic factors controlling N, P, and K accumulation during maize grain development and provide valuable genes for the genetic improvement of nutrient concentrations in maize. 展开更多
关键词 MAIZE nutrient concentration unconditional QTL mapping conditional QTL mapping dynamic trait
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Asymmetric Drying and Wetting Trends in Eastern and Western China 被引量:1
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作者 Wen WU Fei JI +1 位作者 Shujuan HU Yongli HE 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第2期221-232,共12页
As an important factor that directly affects agricultural production, the social economy, and policy implementation,observed changes in dry/wet conditions have become a matter of widespread concern. However, previous ... As an important factor that directly affects agricultural production, the social economy, and policy implementation,observed changes in dry/wet conditions have become a matter of widespread concern. However, previous research has mainly focused on the long-term linear changes of dry/wet conditions, while the detection and evolution of the non-linear trends related to dry/wet changes have received less attention. The non-linear trends of the annual aridity index, obtained by the Ensemble Empirical Mode Decomposition(EEMD) method, reveal that changes in dry/wet conditions in China are asymmetric and can be characterized by contrasting features in both time and space in China. Spatially, most areas in western China have experienced transitions from drying to wetting, while opposite changes have occurred in most areas of eastern China. Temporally, the transitions occurred earlier in western China compared to eastern China. Research into the asymmetric spatial characteristics of dry/wet conditions compensates for the inadequacies of previous studies, which focused solely on temporal evolution;at the same time, it remedies the inadequacies of traditional research on linear trends over centennial timescales. Analyzing the non-linear trend also provides for a more comprehensive understanding of the drying/wetting changes in China. 展开更多
关键词 aridity index EEMD dry/wet conditions asymmetric evolution
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Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis 被引量:1
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作者 Tao Liu Ziqian Ma +8 位作者 Liang Liu Yilun Pei Qichao Wu Songjie Xu Yadong Liu Nan Ding Yun Guan Yan Zhang Xueming Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期1105-1111,共7页
Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery... Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery after spinal cord injury remains unclear.In the present study,we established a rat model of spinal cord injury based on impact injury from a dropped weight and then intraperitoneally injected the rats with conditioned medium from human dental pulp stem cells.We found that the conditioned medium effectively promoted the recovery of sensory and motor functions in rats with spinal cord injury,decreased expression of the microglial pyroptosis markers NLRP3,GSDMD,caspase-1,and interleukin-1β,promoted axonal and myelin regeneration,and inhibited the formation of glial scars.In addition,in a lipopolysaccharide-induced BV2 microglia model,conditioned medium from human dental pulp stem cells protected cells from pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway.These results indicate that conditioned medium from human dental pulp stem cells can reduce microglial pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway,thereby promoting the recovery of neurological function after spinal cord injury.Therefore,conditioned medium from human dental pulp stem cells may become an alternative therapy for spinal cord injury. 展开更多
关键词 BV2 conditioned medium dental pulp stem cells GSDMD MICROGLIA NEUROINFLAMMATION NLRP3 PYROPTOSIS spinal cord injury
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Ambient-Condition Strategy for Production of Hollow Ga_(2)O_(3)@rGO Crystalline Nanostructures Toward Efficient Lithium Storage 被引量:1
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作者 Dongdong Zhang Qiliang Wei +7 位作者 Haili Huang Lan Jiang Jie Teng Ruizhi Yu Qing Zhang Shengxing Liu Lin Wang Weiyou Yang 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第2期75-82,共8页
Crystallineγ-Ga_(2)O_(3)@rGO core-shell nanostructures are synthesized in gram scale,which are accomplished by a facile sonochemical strategy under ambient condition.They are composed of uniformγ-Ga_(2)O_(3)nanosphe... Crystallineγ-Ga_(2)O_(3)@rGO core-shell nanostructures are synthesized in gram scale,which are accomplished by a facile sonochemical strategy under ambient condition.They are composed of uniformγ-Ga_(2)O_(3)nanospheres encapsulated by reduced graphene oxide(rGO)nanolayers,and their formation is mainly attributed to the existed opposite zeta potential between the Ga_(2)O_(3)and rGO.The as-constructed lithium-ion batteries(LIBs)based on as-fabricatedγ-Ga_(2)O_(3)@rGO nanostructures deliver an initial discharge capacity of 1000 mAh g^(-1)at 100 mA g^(-1)and reversible capacity of 600 mAh g^(-1)under 500 mA g^(-1)after 1000 cycles,respectively,which are remarkably higher than those of pristineγ-Ga_(2)O_(3)with a much reduced lifetime of 100 cycles and much lower capacity.Ex situ XRD and XPS analyses demonstrate that the reversible LIBs storage is dominant by a conversion reaction and alloying mechanism,where the discharged product of liquid metal Ga exhibits self-healing ability,thus preventing the destroy of electrodes.Additionally,the rGO shell could act robustly as conductive network of the electrode for significantly improved conductivity,endowing the efficient Li storage behaviors.This work might provide some insight on mass production of advanced electrode materials under mild condition for energy storage and conversion applications. 展开更多
关键词 ambient condition core-shell nanostructures Ga_(2)O_(3) Li-ion batteries rGO
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Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases 被引量:1
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作者 Shahzaib Maqbool Maryam Farhan Baloch +2 位作者 Muhammad Abdul Khaliq Khan Azeem Khalid Kiran Naimat 《World Journal of Transplantation》 2024年第1期32-41,共10页
Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,nega... Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been recorded.Multiple conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and Cochrane.Conditioning regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning regimen.In multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/m2.The comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding LFS.In case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of recurrence.However,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and LFS.With respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding OS.Non-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising results.Lastly,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases. 展开更多
关键词 Conditioning regimens Multiple myeloma LYMPHOMA HODGKIN NON-HODGKIN Acute leukemia
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Bi@C nanosphere anode with Na^(+)-ether-solvent cointercalation behavior to achieve fast sodium storage under extreme low temperatures
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作者 Lingli Liu Siqi Li +7 位作者 Lei Hu Xin Liang Wei Yang Xulai Yang Kunhong Hu Chaofeng Hou Yongsheng Han Shulei Chou 《Carbon Energy》 SCIE EI CAS CSCD 2024年第9期325-337,共13页
The low ion transport is a major obstacle for low-temperature(LT)sodium-ion batteries(SIBs).Herein,a core-shell structure of bismuth(Bi)nanospheres coated with carbon(Bi@C)is constructed by utilizing a novel Bi-based ... The low ion transport is a major obstacle for low-temperature(LT)sodium-ion batteries(SIBs).Herein,a core-shell structure of bismuth(Bi)nanospheres coated with carbon(Bi@C)is constructed by utilizing a novel Bi-based complex(1,4,5,8-naphthalenetetracarboxylic dianhydride as the ligand)as the precursor,which provides an effective template to fabricate Bi-based anodes.At-40℃,the Bi@C anode achieves a high capacity,which is equivalent to 96%of that at 25℃,benefitting from the core-shell nanostructured engineering and Na^(+)-ether-solvent cointercalation process.The special Na+-diglyme cointercalation behavior may effectively reduce the activation energy and accelerate the Na+diffusion kinetics,enabling the excellent low-temperature performance of the Bi@C electrode.As expected,the fabricated Na_(3)V_(2)(PO_(4))_(3)//Bi@C full-cell delivers impressive rechargeability in the ether-based electrolyte at-40℃.Density functional theory calculations and electrochemical tests also reveal the fast reaction kinetic mechanism at LT,thanks to a much lower diffusion energy barrier(167 meV)and a lower reaction activation energy(32.2 kJ mol^(-1))of Bi@C anode in comparison with that of bulk Bi.This work provides a rational design of Bi-based electrodes for rechargeable SIBs under extreme conditions. 展开更多
关键词 BISMUTH CORE-SHELL structure LOW-TEMPERATURE conditions sodium-ion batteries
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Aero-Hydro-Elastic-Servo Modeling and Dynamic Response Analysis of A Monopile Offshore Wind Turbine Under Different Operating Scenarios
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作者 XIE Shuang-yi GAO Jian +3 位作者 LI Yong-ran JIANG Shu-xin ZHANG Cheng-lin HE Jiao 《China Ocean Engineering》 SCIE EI CSCD 2024年第3期379-393,共15页
This paper constructs a coupled aero-hydro-elastic-servo simulation framework for a monopile offshore wind turbine(OWT).In this framework,a detailed multi-body dynamics model of the monopile OWT including the gearbox,... This paper constructs a coupled aero-hydro-elastic-servo simulation framework for a monopile offshore wind turbine(OWT).In this framework,a detailed multi-body dynamics model of the monopile OWT including the gearbox,blades,tower and other components(nacelle,hub,bedplate,etc.)has been explicitly established.The effects of pile−soil interaction,controller and operational conditions on the turbine dynamic responses are studied systematically in time domain and frequency domain.The results show that(1)a comprehensive drivetrain model has the capability to provide a more precise representation of the complex dynamic characteristics exhibited by drivetrain components,which can be used as the basis for further study on the dynamic characteristics of the drivetrain.(2)The pile−soil interaction can influence the wind turbine dynamic responses,particularly under the parked condition.(3)The effect of the pile−soil interaction on tower responses is more significant than that on blade responses.(4)The use of the controller can substantially affect the rotor characteristics,which in turn influences the turbine dynamic responses.(5)The tower and blade displacements under the operational condition are much larger than those under the parked condition.The model and methodology presented in this study demonstrate potential for examining complex dynamic behaviors of the monopile OWTs.To ensure accuracy and precision,it is imperative to construct a detailed model of the wind turbine system,while also taking into account simulation efficiency. 展开更多
关键词 offshore wind turbine(OWT) pile−soil interaction dynamic response parked condition operating condition
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Chitosan-based triboelectric materials for self-powered sensing at high temperatures
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作者 Wencan Chen Chao Li +3 位作者 Yehan Tao Jie Lu Jian Du Haisong Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第11期2518-2527,共10页
Although biopolymers have been widely utilized as triboelectric materials for the construction of self-powered sensing systems,the annihilation of triboelectric charges at high temperatures restricts the output signal... Although biopolymers have been widely utilized as triboelectric materials for the construction of self-powered sensing systems,the annihilation of triboelectric charges at high temperatures restricts the output signals and sensitivity of the assembled sensors.Herein,a novel chitosan/montmorillonite/lignin(CML)composite film was designed and employed as a tribopositive layer in the assembly of a self-powered sensing system for use under hot conditions(25-70℃).The dense contact surface resulting from the strong intermolecular interaction between biopolymers and nanofillers restrained the volatilization of induced electrons.The optimized CML-TENG delivered the highest open-circuit voltage(V_(oc))of 262 V and maximum instantaneous output power of 429 mW/m^(2).Pristine CH-TENG retained only 39%of its initial Voc at 70℃,whereas the optimized CM_(5)L_(3)-TENG retained 66%of its initial Voc.Our work provides a new strategy for suppressing the annihilation of triboelectric charges at high temperatures,thus boosting the development of self-powered sensing devices for application under hot conditions. 展开更多
关键词 CHITOSAN LIGNIN MONTMORILLONITE triboelectric nanogenerator hot conditions
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Role of outdoor trees on pedestrian wind and thermal conditions around a pre-education building for sustainable energy management
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作者 LI Xiao-jie TANG Hui-li 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第6期2039-2053,共15页
Finding sustainable energy resources is essential to face the increasing energy demand.Trees are an important part of ancient architecture but are becoming rare in urban areas.Trees can control and tune the pedestrian... Finding sustainable energy resources is essential to face the increasing energy demand.Trees are an important part of ancient architecture but are becoming rare in urban areas.Trees can control and tune the pedestrian-level wind velocity and thermal condition.In this study,a numerical investigation is employed to assess the role of trees planted in the windward direction of the building complex on the thermal and pedestrian wind velocity conditions around/inside a pre-education building located in the center of the complex.Compared to the previous studies(which considered only outside buildings),this work considers the effects of trees on microclimate change both inside/outside buildings.Effects of different parameters including the leaf area density and number of trees,number of rows,far-field velocity magnitude,and thermal condition around the main building are assessed.The results show that the flow velocity in the spacing between the first-row buildings is reduced by 30%-40% when the one-row trees with 2 m height are planted 15 m farther than the buildings.Furthermore,two rows of trees are more effective in higher velocities and reduce the maximum velocity by about 50%.The investigation shows that trees also could reduce the temperature by about 1℃around the building. 展开更多
关键词 sustainable management energy trees urban area thermal condition building
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Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition:Harnessing the power of nanotheranostics
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作者 Sagnik Nag Oishi Mitra +11 位作者 Bhanu Maturi Simran Preet Kaur Ankita Saini Muskan Nama Soumik Roy Souvik Samanta Leena Chacko Rohan Dutta Suresh Babu Sayana Vetriselvan Subramaniyan Jasvinder Singh Bhatti Ramesh Kandimalla 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2024年第3期79-101,共23页
Autophagy and mitophagy pose unresolved challenges in understanding the pathology of diabetic heart condition(DHC),which encompasses a complex range of cardiovascular issues linked to diabetes and associated cardiomyo... Autophagy and mitophagy pose unresolved challenges in understanding the pathology of diabetic heart condition(DHC),which encompasses a complex range of cardiovascular issues linked to diabetes and associated cardiomyopathies.Despite significant progress in reducing mortality rates from cardiovascular diseases(CVDs),heart failure remains a major cause of increased morbidity among diabetic patients.These cellular processes are essential for maintaining cellular balance and removing damaged or dysfunctional components,and their involvement in the development of diabetic heart disease makes them attractive targets for diagnosis and treatment.While a variety of conventional diagnostic and therapeutic strategies are available,DHC continues to present a significant challenge.Point-of-care diagnostics,supported by nanobiosensing techniques,offer a promising alternative for these complex scenarios.Although conventional medications have been widely used in DHC patients,they raise several concerns regarding various physiological aspects.Modern medicine places great emphasis on the application of nanotechnology to target autophagy and mitophagy in DHC,offering a promising approach to deliver drugs beyond the limitations of traditional therapies.This article aims to explore the potential connections between autophagy,mitophagy and DHC,while also discussing the promise of nanotechnology-based theranostic interventions that specifically target these molecular pathways. 展开更多
关键词 AUTOPHAGY DIABETES Diabetic heart condition MITOPHAGY Nanotheranostics NANOMEDICINE
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AN OPTIMAL CONTROL PROBLEM FOR A LOTKA-VOLTERRA COMPETITION MODEL WITH CHEMO-REPULSION
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作者 Diana I.HERNÁNDEZ Diego A.RUEDA-GOMEZ Élder J.VILLAMIZAR-ROA 《Acta Mathematica Scientia》 SCIE CSCD 2024年第2期721-751,共31页
In this paper we study a bilinear optimal control problem for a diffusive Lotka-Volterra competition model with chemo-repulsion in a bounded domain of ℝ^(ℕ),N=2,3.This model describes the competition of two species in... In this paper we study a bilinear optimal control problem for a diffusive Lotka-Volterra competition model with chemo-repulsion in a bounded domain of ℝ^(ℕ),N=2,3.This model describes the competition of two species in which one of them avoid encounters with rivals through a chemo-repulsion mechanism.We prove the existence and uniqueness of weak-strong solutions,and then we analyze the existence of a global optimal solution for a related bilinear optimal control problem,where the control is acting on the chemical signal.Posteriorly,we derive first-order optimality conditions for local optimal solutions using the Lagrange multipliers theory.Finally,we propose a discrete approximation scheme of the optimality system based on the gradient method,which is validated with some computational experiments. 展开更多
关键词 LOTKA-VOLTERRA chemo-repulsion optimal control optimality conditions
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Features of rare earth elements geochemistry in coals of Central Kazakhstan
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作者 Aiman Nygmetovna Kopobayeva Altynay Amangeldikyzy +1 位作者 Gulim Galymzhanovna Blyalova Nazym Srajadinkyzy Askarova 《Acta Geochimica》 EI CAS CSCD 2024年第5期876-888,共13页
This research presents the results of a comprehensive study of mineralogical and geochemical features of REE distribution in coals of Central Kazakhstan deposits—Karaganda coal basin and Shubarkol deposit,which have ... This research presents the results of a comprehensive study of mineralogical and geochemical features of REE distribution in coals of Central Kazakhstan deposits—Karaganda coal basin and Shubarkol deposit,which have large hard coal reserves and are industrially important for the coal industry of Kazakhstan;the research is based on 205 samples of clayey interlayers and coal seams.It shows basic patterns of distribution and features of concentration for impurity elements,gives an estimate of the impurity elements concentration,including REE,defines conditions and factors of their accumulation,and studies features of their forms in coal and coal-bearing rocks,which allows estimating the mechanisms of their migration and conditions of accumulation.According to the results of geochemical indicators,the article establishes the factors of REE dislocation,reveals the composition of margin rocks that have influenced REE concentration in coal seams,and the presented latest data on mineralogy allowed to establish the ways of their transportation to the paleobasin during the synand epigenetic periods of formation of the coal deposits of Central Kazakhstan being researched.It was found that the coals are insignificantly enriched with heavy lanthanides from Ho to Lu.The distribution curves of UCC normalized REE values in the coals are similar and coincide,but they are less than the average value for world coal,and amount to only one-third of the UCC.It was found that the highest concentrations of all REE are characteristic of clayey interlayers and oxidized coals.The La/Yb ratio in this case increases upwards along the section,indicating mainly clastogenic mechanism of REE delivery to the coals.In coal and clay samples,the predominant mineral form of REE is light lanthanide phosphates.Identified particles of REE from minerals and their composition peculiarities suppose autigene nature of their formation.The formation of the bulk of autigene minerals occurred during the maturation of brown coals and their transformation into hard ones. 展开更多
关键词 Coal REE Impurity elements Accumulation conditions Concentration factors
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Dynamic Vision-Based Machinery Fault Diagnosis With Cross-Modality Feature Alignment
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作者 Xiang Li Shupeng Yu +2 位作者 Yaguo Lei Naipeng Li Bin Yang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第10期2068-2081,共14页
Intelligent machinery fault diagnosis methods have been popularly and successfully developed in the past decades,and the vibration acceleration data collected by contact accelerometers have been widely investigated.In... Intelligent machinery fault diagnosis methods have been popularly and successfully developed in the past decades,and the vibration acceleration data collected by contact accelerometers have been widely investigated.In many industrial scenarios,contactless sensors are more preferred.The event camera is an emerging bio-inspired technology for vision sensing,which asynchronously records per-pixel brightness change polarity with high temporal resolution and low latency.It offers a promising tool for contactless machine vibration sensing and fault diagnosis.However,the dynamic vision-based methods suffer from variations of practical factors such as camera position,machine operating condition,etc.Furthermore,as a new sensing technology,the labeled dynamic vision data are limited,which generally cannot cover a wide range of machine fault modes.Aiming at these challenges,a novel dynamic vision-based machinery fault diagnosis method is proposed in this paper.It is motivated to explore the abundant vibration acceleration data for enhancing the dynamic vision-based model performance.A crossmodality feature alignment method is thus proposed with deep adversarial neural networks to achieve fault diagnosis knowledge transfer.An event erasing method is further proposed for improving model robustness against variations.The proposed method can effectively identify unseen fault mode with dynamic vision data.Experiments on two rotating machine monitoring datasets are carried out for validations,and the results suggest the proposed method is promising for generalized contactless machinery fault diagnosis. 展开更多
关键词 Condition monitoring domain generalization eventbased camera fault diagnosis machine vision
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GmAP1d regulates flowering time under long-day photoperiods in soybean
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作者 Shiyu Guo Yanfei Li +9 位作者 Hongmei Qiu Guoyu Hu Chaosen Zhao Ruizhen Wang Hao Zhang Yu Tian Xiaoyu Li Bin Liu Ying-hui Li Li-juan Qiu 《The Crop Journal》 SCIE CSCD 2024年第3期845-855,共11页
Flowering time is important for adaptation of soybean(Glycine max)to different environments.Here,we conducted a genome-wide association study of flowering time using a panel of 1490 cultivated soybean accessions.We id... Flowering time is important for adaptation of soybean(Glycine max)to different environments.Here,we conducted a genome-wide association study of flowering time using a panel of 1490 cultivated soybean accessions.We identified three strong signals at the qFT02-2 locus(Chr02:12037319–12238569),which were associated with flowering time in three environments:Gongzhuling,Mengcheng,and Nanchang.By analyzing linkage disequilibrium,gene expression patterns,gene annotation,and the diversity of variants,we identified an AP1 homolog as the candidate gene for the qFT02-2 locus,which we named GmAP1d.Only one nonsynonymous polymorphism existed among 1490 soybean accessions at position Chr02:12087053.Accessions carrying the Chr02:12087053-T allele flowered significantly earlier than those carrying the Chr02:12087053-A allele.Thus,we developed a cleaved amplified polymorphic sequence(CAPS)marker for the SNP at Chr02:12087053,which is suitable for marker-assisted breeding of flowering time.Knockout of GmAP1d in the‘Williams 82’background by gene editing promoted flowering under long-day conditions,confirming that GmAP1d is the causal gene for qFT02-2.An analysis of the region surrounding GmAP1d revealed that GmAP1d was artificially selected during the genetic improvement of soybean.Through stepwise selection,the proportion of modern cultivars carrying the Chr02:12087053-T allele has increased,and this allele has become nearly fixed(95%)in northern China.These findings provide a theoretical basis for better understanding the molecular regulatory mechanism of flowering time in soybean and a target gene that can be used for breeding modern soybean cultivars adapted to different latitudes. 展开更多
关键词 SOYBEAN Flowering time GWAS GmAP1d Long-day conditions
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