This three-year study, based on the Guangzhou Institute of Respiratory Disease （GRID）, chronic obstructive pulmonary disease （COPD） Biobank, was conducted in 36 COPD patients to estimate whether changes in levels ...This three-year study, based on the Guangzhou Institute of Respiratory Disease （GRID）, chronic obstructive pulmonary disease （COPD） Biobank, was conducted in 36 COPD patients to estimate whether changes in levels of leukocytes, erythrocytes, hemoglobin, and platelets were related to changes in air pollutant concentration. Daily NO2 levels exhibited significant differences between baseline years and the 2010 Asian Game period. We observed significant reductions in leukocyte and neutrophils counts levels, by 15.51% and 23.01%, from pre-Asian Games to during-Asian Games, respectively. In the post-Asian Game period, most pollutants approximated pre-Asian Game period levels, and similar effects were demonstrated in leukocyte and neutrophil counts. For both items, we identified significant increases resulting from elevated NO2 at lag days 0-2/5-6. We concluded that reductions in pollutants during the intervention period were associated with inactivation of hematological events in COPD.展开更多
Objective:To study the effects of multidisciplinary nursing model on self-care ability,lung function,exercise endurance,negative emotion and quality of life of elderly patients with chronic obstructive pulmonary disea...Objective:To study the effects of multidisciplinary nursing model on self-care ability,lung function,exercise endurance,negative emotion and quality of life of elderly patients with chronic obstructive pulmonary disease(COPD).Methods:80 patients with COPD hospitalized in the Aerospace Center Hospital from August 2019 to August 2020 were recruited.They were randomly divided into control group and experimental group,with 40 patients in each group.The patients in the control group received routine nursing,and the patients in the experimental group received multidisciplinary nursing intervention on the basis of routine nursing.The nursing observation time of the two groups was 8 weeks.Results:after 8 weeks of nursing intervention,it was found that FEV1/FVC and 6MWD in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in SAS score and SDS score between the two groups before nursing,but it was significantly lower in the observation group after nursing.The difference between the above data was statistically significant(P<0.05).The SGRQ score of the observation group was significantly lower than that of the control group(P<0.05).Conclusion:the application of multidisciplinary nursing model can effectively improve the exercise endurance of elderly patients with COPD,eliminate the negative emotions of patients,and improve the quality of life of patients.The comprehensive application value is significant.展开更多
目的:系统评价太极拳对老年COPD患者肺功能和运动能力的干预效果,以期为其提供科学有效的康复处方。方法:计算机检索Science Direct、Web of science、CNKI等数据库,检索年限均从1998年1月至2019年3月,收集太极拳对老年COPD患者肺功能...目的:系统评价太极拳对老年COPD患者肺功能和运动能力的干预效果,以期为其提供科学有效的康复处方。方法:计算机检索Science Direct、Web of science、CNKI等数据库,检索年限均从1998年1月至2019年3月,收集太极拳对老年COPD患者肺功能和运动能力影响的随机对照实验研究,采用效应量与其对应95%置信区间为效应尺度。结果:16篇研究符合纳入标准,文献质量为A级的9篇,为B级的7篇。Meta分析结果:太极拳干预后老年患者FEV1(SMD=0.46,95%CI:0.20~0.72)、FEV1%(SMD=0.35,95%CI:0.21~0.48)、FEV1/FVC%(SMD=0.51,95%CI:0.05~0.97)显著提高,呼吸困难指数明显降低(SMD=-0.38,95%CI:-0.62^-0.13),6WMD明显提高,提高了20.35 m。由于研究间异质性较大,通过单因素Meta回归、亚组分析、敏感性分析探索研究间的异质性来源,同时还发现文献质量A级、干预周期>6个月、每周锻炼频率为3次、每次锻炼时间为>40 min对患者运动能力改善效果最佳。结论:太极拳锻炼能有效改善老年患者肺功能,使患者呼吸更佳顺畅,运动能力明显提高。建议临床工作者制订COPD康复方案时采用此处方。展开更多
基金supported by grants from National Natural Science Foundation of China[81520108001,81700043]the 973 Key Scheme of China[2015CB553406]+2 种基金Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2014,W Lu)Guangzhou Department of Education for Innovative Team[13C08]Guangdong Natural Science Foundation[2016A030313593]
文摘This three-year study, based on the Guangzhou Institute of Respiratory Disease （GRID）, chronic obstructive pulmonary disease （COPD） Biobank, was conducted in 36 COPD patients to estimate whether changes in levels of leukocytes, erythrocytes, hemoglobin, and platelets were related to changes in air pollutant concentration. Daily NO2 levels exhibited significant differences between baseline years and the 2010 Asian Game period. We observed significant reductions in leukocyte and neutrophils counts levels, by 15.51% and 23.01%, from pre-Asian Games to during-Asian Games, respectively. In the post-Asian Game period, most pollutants approximated pre-Asian Game period levels, and similar effects were demonstrated in leukocyte and neutrophil counts. For both items, we identified significant increases resulting from elevated NO2 at lag days 0-2/5-6. We concluded that reductions in pollutants during the intervention period were associated with inactivation of hematological events in COPD.
文摘Objective:To study the effects of multidisciplinary nursing model on self-care ability,lung function,exercise endurance,negative emotion and quality of life of elderly patients with chronic obstructive pulmonary disease(COPD).Methods:80 patients with COPD hospitalized in the Aerospace Center Hospital from August 2019 to August 2020 were recruited.They were randomly divided into control group and experimental group,with 40 patients in each group.The patients in the control group received routine nursing,and the patients in the experimental group received multidisciplinary nursing intervention on the basis of routine nursing.The nursing observation time of the two groups was 8 weeks.Results:after 8 weeks of nursing intervention,it was found that FEV1/FVC and 6MWD in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in SAS score and SDS score between the two groups before nursing,but it was significantly lower in the observation group after nursing.The difference between the above data was statistically significant(P<0.05).The SGRQ score of the observation group was significantly lower than that of the control group(P<0.05).Conclusion:the application of multidisciplinary nursing model can effectively improve the exercise endurance of elderly patients with COPD,eliminate the negative emotions of patients,and improve the quality of life of patients.The comprehensive application value is significant.
