In the face of the corona virus disease 2019(COVID-19)pandemic,it is essential to stabilize the security of urban“shopping baskets”.Through a survey and interviews with 46 agricultural cooperatives in Shanghai,this ...In the face of the corona virus disease 2019(COVID-19)pandemic,it is essential to stabilize the security of urban“shopping baskets”.Through a survey and interviews with 46 agricultural cooperatives in Shanghai,this paper analyzes the impact of the pandemic on vegetable production and offers suggestions on agricultural insurance.The research results show that:(1)the pandemic has impacted almost all stages of the vegetable supply chain but has had a greater impact on the sales stage;(2)the market risks of vegetable production have increased significantly,and the gap between the field price and the market price has widened.The sales price difference between traditional channels and e-commerce is notable;(3)farmers’incomes have generally declined due to the COVID-19 pandemic,and traditional small-scale farmers have suffered more losses;and(4)agricultural insurance plays an important role in stabilizing the supply of vegetables to the city.To minimize the impact of the pandemic on vegetable production and to stabilize both urban“shopping baskets”and farmers’incomes,it is necessary to further improve agricultural insurance,especially to provide insurance against market risks.展开更多
The COVID-19 epidemic has exerted an impact on the global food supply chain,and also has contributed to the tendency of food hoarding and short supply;strong food demand has led to a rapid rise in international food p...The COVID-19 epidemic has exerted an impact on the global food supply chain,and also has contributed to the tendency of food hoarding and short supply;strong food demand has led to a rapid rise in international food prices,which has put enormous pressure on China's food import,and domestic food price showed a rise trend accordingly.In order to ensure sufficient and stable supply of China's food market,it is necessary to adhere to the food security strategy of"food self-sufficiency"for a long term.In the spring agricultural production,Shandong Province has taken effective measures to stabilize food production and achieved good results.It has not been greatly affected by the COVID-19 epidemic;however,under the continuous spread of foreign epidemics,we must adhere to the dual hard core operation of epidemic prevention and production,and explore the establishment of technical specifications for agricultural production under normal conditions for epidemic prevention and control to ensure the food security.展开更多
Under the condition of normalized epidemic,how athletes train and compete well has been in the spotlight.This article reported the symptom,hospitalization and training situation of seven confirmed cases of coronavirus...Under the condition of normalized epidemic,how athletes train and compete well has been in the spotlight.This article reported the symptom,hospitalization and training situation of seven confirmed cases of coronavirusdisease-2019(COVID-19)among Chinese national teams.Moreover,the paper summarized the experience of Chinese national teams in terms of epidemic prevention and control,treatment of infection,and safe return to play.Through a scientific combination of medication and non-medical treatment,seven athletes were all discharged from the hospital.These discharged athletes underwent strict isolation and scientific training before returning to sports teams.Before returning to play,continuous monitoring of physical and mental condition was required.All seven athletes returned to play safely and performed excellently.As for hosting large-scale sporting events,the entire enclosed-loop management from immigration to competition was proposed in this paper.This study could serve as a standard of epidemic prevention and control,treatment for infection and safe return to play during competition and training around the world.展开更多
COVID-19 outbreak has great impact on agricultural and rural farmers.In order to effectively cope with the impact of COVID-19 epidemic and promote agricultural and rural development,this paper expounds the impact of t...COVID-19 outbreak has great impact on agricultural and rural farmers.In order to effectively cope with the impact of COVID-19 epidemic and promote agricultural and rural development,this paper expounds the impact of the epidemic from three aspects of agricultural production,farmers and rural development,and puts forward corresponding countermeasures:building development platform for rural electric business,implementing the development mode of"Internet plus agriculture",strengthening the input and publicity of agricultural insurance to benefit farmers,and increasing support for local employment and entrepreneurship of migrant workers.展开更多
Objective:To understand the current situation of college students'knowledge,cognitive attitude and behavior(KAP)towards the prevention and control of Corona Virus Disease 2019(Corona Virus Disease 2019,COVID-19)du...Objective:To understand the current situation of college students'knowledge,cognitive attitude and behavior(KAP)towards the prevention and control of Corona Virus Disease 2019(Corona Virus Disease 2019,COVID-19)during the epidemic,so as to provide theoretical basis for college students'resumption of study and campus prevention and control.Methods:A questionnaire survey was conducted among 16,410 college students by using the convenient sampling method of,One-Way ANOVA and Logistic regression analysis of the survey data.Results:The total awareness rate of college students on COVID-19 was 85%,the average knowledge score was(70.4±10.0),and the proportion of high cognition was 74.5%.The average attitude score of college students was(3.78±0.55),and only 3.9%of them held a positive attitude.The average score of college students'protective behaviors was(19.35±1.69),and 48.8%of them took good protective behaviors.Binary logistic regression analysis showed that the proportion of students with high cognition who adopt good protective behaviors is higher than that of students with low cognition(95%CI:0.621-0.752).The proportion of students with a positive attitude to adopt good behaviors was higher than that with a negative attitude(95%CI:1.398-2.009),Spearman rank correlation analysis results showed that there was a weak positive correlation between cognition and attitude(r=0.056,P<0.05),and a weak positive correlation between cognition and behavior(r=0.118,P<0.05),and a weak positive correlation between attitude and behavior(r=0.038,P<0.05).Conclusion:College students have a good overall cognition of COVID-19,but their attitudes and protective behaviors need to be further improved.Therefore,knowledge education,behavioral intervention and psychological counseling on COVID-19 epidemic prevention and control among college students should be strengthened to improve their prevention and control ability and physical quality.展开更多
The new coronavirus, officially responsible for COVID-19, has spread rapidly internationally despite multiple countermeasures to limit its transmission. Morocco recorded his first case of COVID-19 on March 02, 2020. T...The new coronavirus, officially responsible for COVID-19, has spread rapidly internationally despite multiple countermeasures to limit its transmission. Morocco recorded his first case of COVID-19 on March 02, 2020. The main data on the pandemic and its evolution come from the Moroccan Ministry of Health. This paper aims to describe the evolution of the pandemic in Morocco and to highlight the different measures taken to stem its progression between March 02 to April 07, 2020. The measures were taken very early since the declaration of the first case in Morocco on March 2, 2020. After 5 weeks of the epidemic, the number of confirmed cases in Morocco reached 1184 including 90 deaths and 93 recoveries. The evolution of the curve seems to be slowed down compared to neighboring countries like Spain. The wearing of a mandatory mask was implemented on April 7 by the Ministry of Health as an additional measure to flatten the curve and allow the health system to effectively cope with the pandemic. The impact of this measure could be assessed by analyzing the evolution of the curve in the coming weeks. Sharing these results can serve as an example to other countries, especially for low-income countries, in their fight against the COVID-19.展开更多
After more than 40 years of development,China's travel agency industry has grown rapidly,but the situation of scattered,small,weak and poor has not fundamentally changed.The unexpected the public health event cris...After more than 40 years of development,China's travel agency industry has grown rapidly,but the situation of scattered,small,weak and poor has not fundamentally changed.The unexpected the public health event crisis of COVID-19 in 2020 has brought great influence on China's travel agency industry,which makes China's travel agency industry face double challenges at home and abroad,but also breeds opportunities for development.In the face of the crisis,China's travel agency industry has responded to it,trying to restore confidence and revive the economy.This paper puts forward some idea from the aspects of crisis management,marketing and product development,including the establishment and implementation of the normalized tourism public crisis response mechanism;the reconstruction of the tourism image of the travel agency industry;the strengthening of marketing,with special attention to new media marketing;the emphasis on natural education,and the enhancement of the upgrading of tourism products.展开更多
The outbreak of COVID-19 in December 2019 has exerted a wide and everlasting impact on the world,which has also influenced education enormously.The adjustment of objective learning environment during the COVID-19 pand...The outbreak of COVID-19 in December 2019 has exerted a wide and everlasting impact on the world,which has also influenced education enormously.The adjustment of objective learning environment during the COVID-19 pandemic makes the influence of non-intellectual factors on college students worthy of investigation,research and analysis.Based on this,we have launched a questionnaire survey on 500 college students who have witnessed the pandemic,and referred to related literature,network documents,news reports,contrast and analysis of college students’non-intelligence factors before and after the outbreak of the different levels of change,summing up some new measures to promote the development of college students’non-intelligence factors under the COVID-19 outbreak for online learning and autonomous learning.展开更多
It has been four years since the concept of“new retail”was proposed,and the layout of“new retail”of several major domestic enterprises has been intensified,which has a“unique landscape”compared to the foreign re...It has been four years since the concept of“new retail”was proposed,and the layout of“new retail”of several major domestic enterprises has been intensified,which has a“unique landscape”compared to the foreign retail landscape.The trend,however,the sudden outbreak and continued spread of the COVID-19 has dealt a serious blow to the global economic development,from the domestic point of view,the epidemic caused by the decline in GDP,leading to a negative year-on-year growth in the total retail sales of consumer goods,the new retail industry is still in the development stage suffered a blow.On the other hand,however,the sinking of the new retail market driven by the consumer economy,the surge of private domain traffic on platforms and the rise of the“house economy”prompted the new retail industry to create new development opportunities during the epidemic,clarifying the development of the new retail industry in the post-epidemic era and pointing out the direction.展开更多
目的:分析新型冠状病毒感染(COVID-19)相关心律失常的文献,探索该领域的研究现状、热点并预测未来的趋势,为后来的研究者提供借鉴。方法:选择Web of Science的核心合集数据库,每项研究都进行了文献计量和视觉分析,使用CiteSpace和VOSvie...目的:分析新型冠状病毒感染(COVID-19)相关心律失常的文献,探索该领域的研究现状、热点并预测未来的趋势,为后来的研究者提供借鉴。方法:选择Web of Science的核心合集数据库,每项研究都进行了文献计量和视觉分析,使用CiteSpace和VOSviewer软件生成知识图谱。结果:共鉴定出768篇文章,发文涉及美国、意大利和中国为首的319个国家/地区和4 366个机构,领先的研究机构是梅奥诊所和哈佛医学院。New England Journal of Medicine是该领域最常被引用的期刊。在6 687位作者中,Arbelo Elena撰写的研究最多,Guo T被共同引用的次数最多,心房纤颤是最常见的关键词。结论:随着COVID-19的暴发,对COVID-19所致新发/进行性心律失常事件的研究蓬勃发展,未来的研究者可能会对COVID-19感染后新发或遗留的快速性心律失常/缓慢性心律失常的发生机制进行进一步的探索。展开更多
目的分析COVID-19疫情暴发前后不同国家经季节和日历调整后的生育率(seasonally and calendar adjusted fertility rate,SAFR)趋势的变化及其影响因素。方法使用国际人类生育力数据库(Human Fertility Database,HFD)中28个国家自2012年...目的分析COVID-19疫情暴发前后不同国家经季节和日历调整后的生育率(seasonally and calendar adjusted fertility rate,SAFR)趋势的变化及其影响因素。方法使用国际人类生育力数据库(Human Fertility Database,HFD)中28个国家自2012年1月至2022年12月的月度SAFR数据,以2020年12月(2020年3月疫情暴发起点加9个月妊娠过程)为节点划分为疫情前(2012.1-2020.11)和疫情后(2020.12-2022.12)进行比较,使用中断时间序列方法分析各国疫情前后的SAFR趋势(短期波动和长期趋势)是否发生变化,使用秩和检验分析疫情前SAFR、人均GDP、公共卫生和社会措施(public health and social measures,PHSM)和失业率是否与SAFR趋势变化有关。结果疫情后28个国家中19个国家的SAFR出现短期下降,随后反弹。对于长期趋势,2个国家由下降趋势转为上升趋势,8个国家由上升趋势转为下降趋势,6个国家的SAFR保持不变。SAFR变化率下降主要集中在部分中欧国家以及地中海西岸的国家,而SAFR变化率增加的国家主要分布在北欧以及西欧地区。SAFR无短期波动的国家疫情前的SAFR低于有短期波动的国家(P=0.041),SAFR变化率下降国家的疫情前SAFR(P=0.005)与人均GDP(P=0.027)均低于SAFR变化率上升国家。未发现SAFR短期波动或长期趋势与PHSM严重程度指数或失业率存在关联。结论COVID-19疫情对28个国家的SAFR造成了不同的短期和长期影响,特别是经济水平和疫情前SAFR相对较低的国家可能更易遭到进一步打击。COVID-19疫情对各国人口的更长期影响值得进一步关注。展开更多
BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from...BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the Middle East assessing the post-ICU discharge mental health status of patients who had COVID-19.AIM To evaluate anxiety and depression among patients who had severe COVID-19.METHODS This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for COVID-19.Eligible patients were contacted via telephone.The patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS score.The secondary outcomes were risk factors of anxiety and/or depression.RESULTS Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the questionnaires.The mean age was 56.3±17.2 years.Thirty patients(62.5%)were male.The main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)diseases.The mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),respectively.Results from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;P<0.05].CONCLUSION Six months after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and depression.To compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.展开更多
BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASLD),characterised by hepatic lipid accumulation,causes inflammation and oxidative stress accompanied by cell damage and fibrosis.Liver injury(LI)i...BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASLD),characterised by hepatic lipid accumulation,causes inflammation and oxidative stress accompanied by cell damage and fibrosis.Liver injury(LI)is also frequently reported in patients hospitalised with coronavirus disease 2019(COVID-19),while preexisting MASLD increases the risk of LI and the development of COVID-19-associated cholangiopathy.Mechanisms of injury at the cellular level remain unclear,but it may be significant that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)which causes COVID-19,uses angiotensin-converting expression enzyme 2(ACE2),a key regulator of the‘anti-inflammatory’arm of the renin-angiotensin system,for viral attachment and host cell invasion.AIM To determine if hepatic ACE2 levels are altered during progression of MASLD and in patients who died with severe COVID-19.METHODS ACE2 protein levels and localisation,and histological fibrosis and lipid droplet accumulation as markers of MASLD were determined in formalin-fixed liver tissue sections across the MASLD pathological spectrum(isolated hepatocellular steatosis,metabolic dysfunction-associated steatohepatitis(MASH)+/-fibrosis,end-stage cirrhosis)and in post-mortem tissues from patients who had died with severe COVID-19,using ACE2 immunohistochemistry and haematoxylin and eosin and picrosirius red staining of total collagen and lipid droplet areas,followed by quantification using machine learning-based image pixel classifiers.RESULTS ACE2 staining is primarily intracellular and concentrated in the cytoplasm of centrilobular hepatocytes and apical membranes of bile duct cholangiocytes.Strikingly,ACE2 protein levels are elevated in non-fibrotic MASH compared to healthy controls but not in the progression to MASH with fibrosis and in cirrhosis.ACE2 protein levels and histological fibrosis are not associated,but ACE2 and liver lipid droplet content are significantly correlated across the MASLD spectrum.Hepatic ACE2 levels are also increased in COVID-19 patients,especially those showing evidence of LI,but are not correlated with the presence of SARS-CoV-2 virus in the liver.However,there is a clear association between the hepatic lipid droplet content and the presence of the virus,suggesting a possible functional link.CONCLUSION Hepatic ACE2 levels were elevated in nonfibrotic MASH and COVID-19 patients with LI,while lipid accumulation may promote intra-hepatic SARS-CoV-2 replication,accelerating MASLD progression and COVID-19-mediated liver damage.展开更多
Background:Solid organ transplant(SOT)activities,such as liver transplant,have been greatly influenced by the pandemic of coronavirus disease 2019(COVID-19),a disease caused by severe acute respiratory syndrome corona...Background:Solid organ transplant(SOT)activities,such as liver transplant,have been greatly influenced by the pandemic of coronavirus disease 2019(COVID-19),a disease caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Immunosuppressed individuals of liver transplant recipients(LTRs)tend to have a high risk of COVID-19 infection and related complications.Therefore,COVID-19 vaccination has been recommended to be administered as early as possible in LTRs.Data sources:The keywords“liver transplant”,“SARS-CoV-2”,and“vaccine”were used to retrieve articles published in PubMed.Results:The antibody response following the 1st and 2nd doses of vaccination was disappointingly low,and the immune responses among LTRs remarkably improved after the 3rd or 4th dose of vaccination.Although the 3rd or 4th dose of COVID-19 vaccine increased the antibody titer,a proportion of patients remained unresponsive.Furthermore,recent studies showed that SARS-CoV-2 vaccine could trigger adverse events in LTRs,including allograft rejection and liver injury.Conclusions:This review provides the recently reported data on the antibody response of LTRs following various doses of vaccine,risk factors for poor serological response and adverse events after vaccination.展开更多
基金This study was supported by the Humanity and Social Science Youth Fund of the Ministry of Education of China(18YJC790157)the National Social Science Fund of China(16ZDA019).
文摘In the face of the corona virus disease 2019(COVID-19)pandemic,it is essential to stabilize the security of urban“shopping baskets”.Through a survey and interviews with 46 agricultural cooperatives in Shanghai,this paper analyzes the impact of the pandemic on vegetable production and offers suggestions on agricultural insurance.The research results show that:(1)the pandemic has impacted almost all stages of the vegetable supply chain but has had a greater impact on the sales stage;(2)the market risks of vegetable production have increased significantly,and the gap between the field price and the market price has widened.The sales price difference between traditional channels and e-commerce is notable;(3)farmers’incomes have generally declined due to the COVID-19 pandemic,and traditional small-scale farmers have suffered more losses;and(4)agricultural insurance plays an important role in stabilizing the supply of vegetables to the city.To minimize the impact of the pandemic on vegetable production and to stabilize both urban“shopping baskets”and farmers’incomes,it is necessary to further improve agricultural insurance,especially to provide insurance against market risks.
基金Innovation Project of Shandong Seed Industry Group Co.,Ltd."Research on the Path and Countermeasures for Food Security under the Impact of COVID-19 Epidemic"(20200401)。
文摘The COVID-19 epidemic has exerted an impact on the global food supply chain,and also has contributed to the tendency of food hoarding and short supply;strong food demand has led to a rapid rise in international food prices,which has put enormous pressure on China's food import,and domestic food price showed a rise trend accordingly.In order to ensure sufficient and stable supply of China's food market,it is necessary to adhere to the food security strategy of"food self-sufficiency"for a long term.In the spring agricultural production,Shandong Province has taken effective measures to stabilize food production and achieved good results.It has not been greatly affected by the COVID-19 epidemic;however,under the continuous spread of foreign epidemics,we must adhere to the dual hard core operation of epidemic prevention and production,and explore the establishment of technical specifications for agricultural production under normal conditions for epidemic prevention and control to ensure the food security.
基金supported by the China Association for Science and Technology(Project Number:2021ZZGJB070734)National Key Research and Development Program of China(Project Number:2018YFF0300604)National Key Research and Development Program of China(Project Number:2019YFF0301703).
文摘Under the condition of normalized epidemic,how athletes train and compete well has been in the spotlight.This article reported the symptom,hospitalization and training situation of seven confirmed cases of coronavirusdisease-2019(COVID-19)among Chinese national teams.Moreover,the paper summarized the experience of Chinese national teams in terms of epidemic prevention and control,treatment of infection,and safe return to play.Through a scientific combination of medication and non-medical treatment,seven athletes were all discharged from the hospital.These discharged athletes underwent strict isolation and scientific training before returning to sports teams.Before returning to play,continuous monitoring of physical and mental condition was required.All seven athletes returned to play safely and performed excellently.As for hosting large-scale sporting events,the entire enclosed-loop management from immigration to competition was proposed in this paper.This study could serve as a standard of epidemic prevention and control,treatment for infection and safe return to play during competition and training around the world.
文摘COVID-19 outbreak has great impact on agricultural and rural farmers.In order to effectively cope with the impact of COVID-19 epidemic and promote agricultural and rural development,this paper expounds the impact of the epidemic from three aspects of agricultural production,farmers and rural development,and puts forward corresponding countermeasures:building development platform for rural electric business,implementing the development mode of"Internet plus agriculture",strengthening the input and publicity of agricultural insurance to benefit farmers,and increasing support for local employment and entrepreneurship of migrant workers.
基金Hainan University Scientific Research Project(No.HNKY2020-44)
文摘Objective:To understand the current situation of college students'knowledge,cognitive attitude and behavior(KAP)towards the prevention and control of Corona Virus Disease 2019(Corona Virus Disease 2019,COVID-19)during the epidemic,so as to provide theoretical basis for college students'resumption of study and campus prevention and control.Methods:A questionnaire survey was conducted among 16,410 college students by using the convenient sampling method of,One-Way ANOVA and Logistic regression analysis of the survey data.Results:The total awareness rate of college students on COVID-19 was 85%,the average knowledge score was(70.4±10.0),and the proportion of high cognition was 74.5%.The average attitude score of college students was(3.78±0.55),and only 3.9%of them held a positive attitude.The average score of college students'protective behaviors was(19.35±1.69),and 48.8%of them took good protective behaviors.Binary logistic regression analysis showed that the proportion of students with high cognition who adopt good protective behaviors is higher than that of students with low cognition(95%CI:0.621-0.752).The proportion of students with a positive attitude to adopt good behaviors was higher than that with a negative attitude(95%CI:1.398-2.009),Spearman rank correlation analysis results showed that there was a weak positive correlation between cognition and attitude(r=0.056,P<0.05),and a weak positive correlation between cognition and behavior(r=0.118,P<0.05),and a weak positive correlation between attitude and behavior(r=0.038,P<0.05).Conclusion:College students have a good overall cognition of COVID-19,but their attitudes and protective behaviors need to be further improved.Therefore,knowledge education,behavioral intervention and psychological counseling on COVID-19 epidemic prevention and control among college students should be strengthened to improve their prevention and control ability and physical quality.
文摘The new coronavirus, officially responsible for COVID-19, has spread rapidly internationally despite multiple countermeasures to limit its transmission. Morocco recorded his first case of COVID-19 on March 02, 2020. The main data on the pandemic and its evolution come from the Moroccan Ministry of Health. This paper aims to describe the evolution of the pandemic in Morocco and to highlight the different measures taken to stem its progression between March 02 to April 07, 2020. The measures were taken very early since the declaration of the first case in Morocco on March 2, 2020. After 5 weeks of the epidemic, the number of confirmed cases in Morocco reached 1184 including 90 deaths and 93 recoveries. The evolution of the curve seems to be slowed down compared to neighboring countries like Spain. The wearing of a mandatory mask was implemented on April 7 by the Ministry of Health as an additional measure to flatten the curve and allow the health system to effectively cope with the pandemic. The impact of this measure could be assessed by analyzing the evolution of the curve in the coming weeks. Sharing these results can serve as an example to other countries, especially for low-income countries, in their fight against the COVID-19.
文摘After more than 40 years of development,China's travel agency industry has grown rapidly,but the situation of scattered,small,weak and poor has not fundamentally changed.The unexpected the public health event crisis of COVID-19 in 2020 has brought great influence on China's travel agency industry,which makes China's travel agency industry face double challenges at home and abroad,but also breeds opportunities for development.In the face of the crisis,China's travel agency industry has responded to it,trying to restore confidence and revive the economy.This paper puts forward some idea from the aspects of crisis management,marketing and product development,including the establishment and implementation of the normalized tourism public crisis response mechanism;the reconstruction of the tourism image of the travel agency industry;the strengthening of marketing,with special attention to new media marketing;the emphasis on natural education,and the enhancement of the upgrading of tourism products.
基金This paper is part of the achievements of the CFL’s Undergraduate Project:An Investigation on the Influence of COVID-19 on Non intellectual Factors of College Students at USST in 2022.
文摘The outbreak of COVID-19 in December 2019 has exerted a wide and everlasting impact on the world,which has also influenced education enormously.The adjustment of objective learning environment during the COVID-19 pandemic makes the influence of non-intellectual factors on college students worthy of investigation,research and analysis.Based on this,we have launched a questionnaire survey on 500 college students who have witnessed the pandemic,and referred to related literature,network documents,news reports,contrast and analysis of college students’non-intelligence factors before and after the outbreak of the different levels of change,summing up some new measures to promote the development of college students’non-intelligence factors under the COVID-19 outbreak for online learning and autonomous learning.
文摘It has been four years since the concept of“new retail”was proposed,and the layout of“new retail”of several major domestic enterprises has been intensified,which has a“unique landscape”compared to the foreign retail landscape.The trend,however,the sudden outbreak and continued spread of the COVID-19 has dealt a serious blow to the global economic development,from the domestic point of view,the epidemic caused by the decline in GDP,leading to a negative year-on-year growth in the total retail sales of consumer goods,the new retail industry is still in the development stage suffered a blow.On the other hand,however,the sinking of the new retail market driven by the consumer economy,the surge of private domain traffic on platforms and the rise of the“house economy”prompted the new retail industry to create new development opportunities during the epidemic,clarifying the development of the new retail industry in the post-epidemic era and pointing out the direction.
文摘目的:分析新型冠状病毒感染(COVID-19)相关心律失常的文献,探索该领域的研究现状、热点并预测未来的趋势,为后来的研究者提供借鉴。方法:选择Web of Science的核心合集数据库,每项研究都进行了文献计量和视觉分析,使用CiteSpace和VOSviewer软件生成知识图谱。结果:共鉴定出768篇文章,发文涉及美国、意大利和中国为首的319个国家/地区和4 366个机构,领先的研究机构是梅奥诊所和哈佛医学院。New England Journal of Medicine是该领域最常被引用的期刊。在6 687位作者中,Arbelo Elena撰写的研究最多,Guo T被共同引用的次数最多,心房纤颤是最常见的关键词。结论:随着COVID-19的暴发,对COVID-19所致新发/进行性心律失常事件的研究蓬勃发展,未来的研究者可能会对COVID-19感染后新发或遗留的快速性心律失常/缓慢性心律失常的发生机制进行进一步的探索。
文摘目的分析COVID-19疫情暴发前后不同国家经季节和日历调整后的生育率(seasonally and calendar adjusted fertility rate,SAFR)趋势的变化及其影响因素。方法使用国际人类生育力数据库(Human Fertility Database,HFD)中28个国家自2012年1月至2022年12月的月度SAFR数据,以2020年12月(2020年3月疫情暴发起点加9个月妊娠过程)为节点划分为疫情前(2012.1-2020.11)和疫情后(2020.12-2022.12)进行比较,使用中断时间序列方法分析各国疫情前后的SAFR趋势(短期波动和长期趋势)是否发生变化,使用秩和检验分析疫情前SAFR、人均GDP、公共卫生和社会措施(public health and social measures,PHSM)和失业率是否与SAFR趋势变化有关。结果疫情后28个国家中19个国家的SAFR出现短期下降,随后反弹。对于长期趋势,2个国家由下降趋势转为上升趋势,8个国家由上升趋势转为下降趋势,6个国家的SAFR保持不变。SAFR变化率下降主要集中在部分中欧国家以及地中海西岸的国家,而SAFR变化率增加的国家主要分布在北欧以及西欧地区。SAFR无短期波动的国家疫情前的SAFR低于有短期波动的国家(P=0.041),SAFR变化率下降国家的疫情前SAFR(P=0.005)与人均GDP(P=0.027)均低于SAFR变化率上升国家。未发现SAFR短期波动或长期趋势与PHSM严重程度指数或失业率存在关联。结论COVID-19疫情对28个国家的SAFR造成了不同的短期和长期影响,特别是经济水平和疫情前SAFR相对较低的国家可能更易遭到进一步打击。COVID-19疫情对各国人口的更长期影响值得进一步关注。
基金the Researchers Supporting Project number,King Saud University,Riyadh,Saudi Arabia,No.RSPD2024R919.
文摘BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the Middle East assessing the post-ICU discharge mental health status of patients who had COVID-19.AIM To evaluate anxiety and depression among patients who had severe COVID-19.METHODS This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for COVID-19.Eligible patients were contacted via telephone.The patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS score.The secondary outcomes were risk factors of anxiety and/or depression.RESULTS Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the questionnaires.The mean age was 56.3±17.2 years.Thirty patients(62.5%)were male.The main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)diseases.The mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),respectively.Results from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;P<0.05].CONCLUSION Six months after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and depression.To compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.
基金Supported by University of Edinburgh Hepatology Laboratory Internal Fundingthe Liver Endowment Funds of the Edinburgh&Lothian Health Foundation.
文摘BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASLD),characterised by hepatic lipid accumulation,causes inflammation and oxidative stress accompanied by cell damage and fibrosis.Liver injury(LI)is also frequently reported in patients hospitalised with coronavirus disease 2019(COVID-19),while preexisting MASLD increases the risk of LI and the development of COVID-19-associated cholangiopathy.Mechanisms of injury at the cellular level remain unclear,but it may be significant that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)which causes COVID-19,uses angiotensin-converting expression enzyme 2(ACE2),a key regulator of the‘anti-inflammatory’arm of the renin-angiotensin system,for viral attachment and host cell invasion.AIM To determine if hepatic ACE2 levels are altered during progression of MASLD and in patients who died with severe COVID-19.METHODS ACE2 protein levels and localisation,and histological fibrosis and lipid droplet accumulation as markers of MASLD were determined in formalin-fixed liver tissue sections across the MASLD pathological spectrum(isolated hepatocellular steatosis,metabolic dysfunction-associated steatohepatitis(MASH)+/-fibrosis,end-stage cirrhosis)and in post-mortem tissues from patients who had died with severe COVID-19,using ACE2 immunohistochemistry and haematoxylin and eosin and picrosirius red staining of total collagen and lipid droplet areas,followed by quantification using machine learning-based image pixel classifiers.RESULTS ACE2 staining is primarily intracellular and concentrated in the cytoplasm of centrilobular hepatocytes and apical membranes of bile duct cholangiocytes.Strikingly,ACE2 protein levels are elevated in non-fibrotic MASH compared to healthy controls but not in the progression to MASH with fibrosis and in cirrhosis.ACE2 protein levels and histological fibrosis are not associated,but ACE2 and liver lipid droplet content are significantly correlated across the MASLD spectrum.Hepatic ACE2 levels are also increased in COVID-19 patients,especially those showing evidence of LI,but are not correlated with the presence of SARS-CoV-2 virus in the liver.However,there is a clear association between the hepatic lipid droplet content and the presence of the virus,suggesting a possible functional link.CONCLUSION Hepatic ACE2 levels were elevated in nonfibrotic MASH and COVID-19 patients with LI,while lipid accumulation may promote intra-hepatic SARS-CoV-2 replication,accelerating MASLD progression and COVID-19-mediated liver damage.
基金the National Natural Science Foundation of China(82103662).
文摘Background:Solid organ transplant(SOT)activities,such as liver transplant,have been greatly influenced by the pandemic of coronavirus disease 2019(COVID-19),a disease caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Immunosuppressed individuals of liver transplant recipients(LTRs)tend to have a high risk of COVID-19 infection and related complications.Therefore,COVID-19 vaccination has been recommended to be administered as early as possible in LTRs.Data sources:The keywords“liver transplant”,“SARS-CoV-2”,and“vaccine”were used to retrieve articles published in PubMed.Results:The antibody response following the 1st and 2nd doses of vaccination was disappointingly low,and the immune responses among LTRs remarkably improved after the 3rd or 4th dose of vaccination.Although the 3rd or 4th dose of COVID-19 vaccine increased the antibody titer,a proportion of patients remained unresponsive.Furthermore,recent studies showed that SARS-CoV-2 vaccine could trigger adverse events in LTRs,including allograft rejection and liver injury.Conclusions:This review provides the recently reported data on the antibody response of LTRs following various doses of vaccine,risk factors for poor serological response and adverse events after vaccination.