A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature,short and stubby hands and feet,language disorders and mental retardation.He developed bilateral angle closu...A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature,short and stubby hands and feet,language disorders and mental retardation.He developed bilateral angle closure glaucoma,ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani syndrome.The child was successfully treated by combined CO_(2) laser-assisted sclerectomy surgery and trabeculectomy.展开更多
目的探究窄带成像联合显微镜下CO_(2)激光手术治疗声带白斑的临床效果及应用价值。方法选取该院2018年5月—2021年4月收治的声带白斑患者40例,根据简单随机抽样的原则分为研究组和对照组,各20例。研究组行窄带成像(narrow band imaging,...目的探究窄带成像联合显微镜下CO_(2)激光手术治疗声带白斑的临床效果及应用价值。方法选取该院2018年5月—2021年4月收治的声带白斑患者40例,根据简单随机抽样的原则分为研究组和对照组,各20例。研究组行窄带成像(narrow band imaging,NBI)联合显微镜下CO_(2)激光手术治疗,对照组行电子喉镜下手术治疗,对比两组术中声带损伤情况、术后声嘶改善和声带恢复效果,以及追踪声带白斑复发情况。结果在NBI模式下对研究组20例患者的病变声带进行分型,结果显示:Ⅲ型12例(60%),Ⅳ型2例(10%),Va型6例(30%)。根据术后病理学检查结果所示:单纯增生10例(50%),轻度不典型增生1例(5%),中度不典型增生2例(10%),重度不典型增生2例(10%),原位癌5例(25%)。对照组治疗有效率仅为75%,明显低于研究组的90%,差异有统计学意义(P<0.05)。与病理分型结果对比,可得,研究组NBI内镜的准确判断性为83.3%,采用Kappa一致性检验法,NBI内镜判断结果与病理结果存在一致性(Κ=0.659,P<0.001)。研究组声带白斑的复发率为0%,显著低于对照组的25%,差异有统计学意义(P<0.05);研究组并发症发生率为5%,对照组为10%,差异无统计学意义(P>0.05)。结论窄带成像联合显微镜下CO_(2)激光手术治疗,可以提高病变组织分型的诊断正确率,有效减少术中声带损伤,减少并发症,降低复发率,更有效安全,有良好的临床效果和应用价值。展开更多
BACKGROUND This case of gestational gingival tumor is huge and extremely rare in clinical practice.As the growth location of this gingival tumor is in the upper anterior tooth area,it seriously affects the pregnant wo...BACKGROUND This case of gestational gingival tumor is huge and extremely rare in clinical practice.As the growth location of this gingival tumor is in the upper anterior tooth area,it seriously affects the pregnant woman's speech and food,causing great pain to the patient.The use of Nd:YGA water mist laser to remove the gingival tumor resulted in minimal intraoperative bleeding,minimal adverse reactions,and good postoperative healing,which is worthy of clinical promotion and application.CASE SUMMARY The patient,a pregnant woman,reported a large lump in her mouth on the first day of postpartum treatment.Based on medical history and clinical examination,the diagnosis was diagnosed as gestational gingival tumor.Postoperative pathological biopsy also confirmed this diagnosis.The use of Nd:YAG water mist laser to remove the tumor resulted in minimal intraoperative bleeding,clear surgical field of view,short surgical time,and good postoperative healing.CONCLUSION In comparison to traditional surgery,Nd:YAG water mist laser surgery is minimally invasive,minimizes cell damage,reduces bleeding,ensures a clear field of vision,and virtually eliminates postoperative edema,carbonization,and the risk of cross infection.It has unique advantages in oral soft tissue surgery for pregnant patients.Therefore,the clinical application of Nd:YAG water mist laser for the treatment of gestational gingival tumors is an ideal choice.展开更多
AIM: To investigate which surgical techniques and perioperative regimens yielded the best survival rates for diabetic rats undergoing gastric bypass. METHODS: We performed Roux-en-Y gastric bypass with reserved gastri...AIM: To investigate which surgical techniques and perioperative regimens yielded the best survival rates for diabetic rats undergoing gastric bypass. METHODS: We performed Roux-en-Y gastric bypass with reserved gastric volume, a procedure in which gastrointestinal continuity was reestablished while excluding the entire duodenum and proximal jejunal loop. We observed the procedural success rate, long-term survival, and histopathological sequelae associated with a number of technical modifications. These included: use of anatomical markers to precisely identify Treitz's ligament; careful dissection along surgical planes; careful attention to the choice of regional transection sites; reconstruction using full-thickness anastomoses; use of a minimally invasive procedure with prohemostatic pretreatment and hemorrhage control; prevention of hypo-thermic damage; reduction in the length of the procedure; and accelerated surgical recovery using fast-track surgical modalities such as perioperative permissive underfeeding and goal-directed volume therapy. RESULTS: The series of modif ications we adopted reduced operation time from 110.02 ± 12.34 min to 78.39 ± 7.26 min (P < 0.01), and the procedural success rate increased from 43.3% (13/30) to 90% (18/20) (P < 0.01), with a long-term survival of 83.3% (15/18) (P < 0.01). CONCLUSION: Using a number of fast-track and damage control surgical techniques, we have successfully established a stable model of gastric bypass in diabetic rats.展开更多
文摘A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature,short and stubby hands and feet,language disorders and mental retardation.He developed bilateral angle closure glaucoma,ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani syndrome.The child was successfully treated by combined CO_(2) laser-assisted sclerectomy surgery and trabeculectomy.
文摘目的探究窄带成像联合显微镜下CO_(2)激光手术治疗声带白斑的临床效果及应用价值。方法选取该院2018年5月—2021年4月收治的声带白斑患者40例,根据简单随机抽样的原则分为研究组和对照组,各20例。研究组行窄带成像(narrow band imaging,NBI)联合显微镜下CO_(2)激光手术治疗,对照组行电子喉镜下手术治疗,对比两组术中声带损伤情况、术后声嘶改善和声带恢复效果,以及追踪声带白斑复发情况。结果在NBI模式下对研究组20例患者的病变声带进行分型,结果显示:Ⅲ型12例(60%),Ⅳ型2例(10%),Va型6例(30%)。根据术后病理学检查结果所示:单纯增生10例(50%),轻度不典型增生1例(5%),中度不典型增生2例(10%),重度不典型增生2例(10%),原位癌5例(25%)。对照组治疗有效率仅为75%,明显低于研究组的90%,差异有统计学意义(P<0.05)。与病理分型结果对比,可得,研究组NBI内镜的准确判断性为83.3%,采用Kappa一致性检验法,NBI内镜判断结果与病理结果存在一致性(Κ=0.659,P<0.001)。研究组声带白斑的复发率为0%,显著低于对照组的25%,差异有统计学意义(P<0.05);研究组并发症发生率为5%,对照组为10%,差异无统计学意义(P>0.05)。结论窄带成像联合显微镜下CO_(2)激光手术治疗,可以提高病变组织分型的诊断正确率,有效减少术中声带损伤,减少并发症,降低复发率,更有效安全,有良好的临床效果和应用价值。
文摘BACKGROUND This case of gestational gingival tumor is huge and extremely rare in clinical practice.As the growth location of this gingival tumor is in the upper anterior tooth area,it seriously affects the pregnant woman's speech and food,causing great pain to the patient.The use of Nd:YGA water mist laser to remove the gingival tumor resulted in minimal intraoperative bleeding,minimal adverse reactions,and good postoperative healing,which is worthy of clinical promotion and application.CASE SUMMARY The patient,a pregnant woman,reported a large lump in her mouth on the first day of postpartum treatment.Based on medical history and clinical examination,the diagnosis was diagnosed as gestational gingival tumor.Postoperative pathological biopsy also confirmed this diagnosis.The use of Nd:YAG water mist laser to remove the tumor resulted in minimal intraoperative bleeding,clear surgical field of view,short surgical time,and good postoperative healing.CONCLUSION In comparison to traditional surgery,Nd:YAG water mist laser surgery is minimally invasive,minimizes cell damage,reduces bleeding,ensures a clear field of vision,and virtually eliminates postoperative edema,carbonization,and the risk of cross infection.It has unique advantages in oral soft tissue surgery for pregnant patients.Therefore,the clinical application of Nd:YAG water mist laser for the treatment of gestational gingival tumors is an ideal choice.
基金Supported by Scientific Research Fund of Heilongjiang Provincial Education Department, No. 11541200Harbin Medical University First Affi liated Hospital, No. 2007098
文摘AIM: To investigate which surgical techniques and perioperative regimens yielded the best survival rates for diabetic rats undergoing gastric bypass. METHODS: We performed Roux-en-Y gastric bypass with reserved gastric volume, a procedure in which gastrointestinal continuity was reestablished while excluding the entire duodenum and proximal jejunal loop. We observed the procedural success rate, long-term survival, and histopathological sequelae associated with a number of technical modifications. These included: use of anatomical markers to precisely identify Treitz's ligament; careful dissection along surgical planes; careful attention to the choice of regional transection sites; reconstruction using full-thickness anastomoses; use of a minimally invasive procedure with prohemostatic pretreatment and hemorrhage control; prevention of hypo-thermic damage; reduction in the length of the procedure; and accelerated surgical recovery using fast-track surgical modalities such as perioperative permissive underfeeding and goal-directed volume therapy. RESULTS: The series of modif ications we adopted reduced operation time from 110.02 ± 12.34 min to 78.39 ± 7.26 min (P < 0.01), and the procedural success rate increased from 43.3% (13/30) to 90% (18/20) (P < 0.01), with a long-term survival of 83.3% (15/18) (P < 0.01). CONCLUSION: Using a number of fast-track and damage control surgical techniques, we have successfully established a stable model of gastric bypass in diabetic rats.