A four-step synthesis of methyl 6-formyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate(11)that can be used as building block for a facile synthesis of cajaninstilbene acid and its derivatives is reported.The s...A four-step synthesis of methyl 6-formyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate(11)that can be used as building block for a facile synthesis of cajaninstilbene acid and its derivatives is reported.The synthesis of cajaninstilbene acid was accomplished in six steps with an overall yield of 20%starting from commercial materials by a synthesis whose key steps are TiCl4-mediated[3+3]cyclization and McMurry coupling.展开更多
基金supported by the National Natural Science Foundation of China (No. 81673336)
文摘A four-step synthesis of methyl 6-formyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate(11)that can be used as building block for a facile synthesis of cajaninstilbene acid and its derivatives is reported.The synthesis of cajaninstilbene acid was accomplished in six steps with an overall yield of 20%starting from commercial materials by a synthesis whose key steps are TiCl4-mediated[3+3]cyclization and McMurry coupling.
