Determination of the Stability Studies of the Sudanese Camel Insulin

The main objective of the presented study was to characterize the stability of the Sudanese camel insulin after 6 months of its extraction, purification and formulation from the fresh pancreatic glands of the camel, slaughtered for local and export consumption. The stability and purity of the formulated insulin samples were compared to standard insulin sam-ples that of the leading manufacturing companies using some analytical techniques such as HPLC, gel electrophoresis and atomic absorption. In another part of the study, the direct transfer method was used to accomplish sterility test by complete immersion of the insulin samples into thioglycollate and soybean medium. The data were presented as mean ± S.E.M (standard error of means) for the comparison of zinc (mg/units) and nitrogen (in percentage) concentrations in standard and testing camel insulin samples, respectively. Similarly, the linear equation was derived and the coefficient factors for standard and testing insulin samples were compared to determine the peak area and the concentrations of the camel insulin samples (mean ± S.E.M) after HPLC elution. The P value,

骆驼奶中脂肪酸含量的测定与分析

采用气相色谱和气相质谱测定了骆驼奶、牛奶、羊奶、人奶中的脂肪酸组成和含量.结果表明:在骆驼奶中共检测出11种脂肪酸,其中,不饱和脂肪酸在总脂肪酸中的比例(65.02%)极显著高于牛奶(40.76%)、羊奶(40.23%)、人奶(58.17%)(P<0.01),尤其是骆驼奶中的亚麻酸(C18:3)含量(5.09%)极显著高于牛奶(0.36%)、羊奶(0.34%)、人奶(2.96%)(P<0.01).

新疆双峰驼乳中胰岛素含量测定

采用酶联免疫法（ELISA）对7峰新疆双峰驼乳中的胰岛素含量（浓度）进行了测定。结果显示,驼乳中胰岛素平均含量为63.76±7.77μU/m L,测定结果范围为56.25~74.90μU/m L。

甘肃双峰驼乳对糖尿病大鼠的辅助治疗效果

研究骆驼乳对高脂饮食造成的糖尿病大鼠模型的辅助治疗效果。应用高脂饲料制造大鼠的糖尿病模型,筛选血糖值高于正常对照组均数加标准差的糖尿病大鼠作为作为实验组。分别给予蒸馏水、药物、药物加驼乳及驼乳,灌胃8周后处死动物检测空腹血糖、甘油三酯、总胆固醇和胰岛素,计算胰岛素抵抗指数。结果表明,与空白对照组比较,病例对照组各指标均有显著性差异(P﹤0.05)。其余3个实验组与空白组比较各指标差异无显著性(P﹥0.05),与病例对照组相比差异有统计学意义(P﹤0.05)。骆驼乳对糖尿病大鼠有辅助治疗作用,具有极大的开发和利用价值。

驼乳对Ⅱ型糖尿病小鼠的糖脂代谢及胰岛素抵抗的影响

本文研究了驼乳对Ⅱ型糖尿病小鼠糖脂代谢及胰岛素抵抗的影响。通过链脲佐菌素(STZ)与高脂饲料联合诱导建立Ⅱ型糖尿病小鼠为模型,检测驼乳对糖尿病小鼠空腹血糖(FBG)、口服葡萄糖耐量(OGTT)、胰岛素耐量(ITT)、总胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白(DL)、高密度脂蛋白(HDL)、胰岛素抵抗等指标的影响。结果显示:与糖尿病模型组(DC)相比,驼乳干预组(CM)小鼠的空腹血糖值极显著降低(P<0.01),胰岛素耐量与葡萄糖耐量显著改善,小鼠的血清总胆固醇、甘油三脂以及低密度脂蛋白含量显著降低(P<0.05),高密度脂蛋白/总胆固醇的比值极显著提高(P<0.01)。驼乳干预后小鼠的血清胰岛素水平、胰岛素抵抗指数与胰岛素敏感指数与DC相比,存在极显著差异。试验结果证实,驼乳能够改善Ⅱ型糖尿病小鼠糖脂代谢及胰岛素抵抗。