Objective： To discuss the epidemic strength of cardia and distant stomach cancers in the high risk region of esophageal cancer along the south Taihang mountain such as in Shexian, Linxian, and Cixian Counties, and to...Objective： To discuss the epidemic strength of cardia and distant stomach cancers in the high risk region of esophageal cancer along the south Taihang mountain such as in Shexian, Linxian, and Cixian Counties, and to clarify the tasks for the control of upper gastrointestinal tract cancer as a whole in the region. Methods： Comparisons of incidence and mortality rates of esophageal, cardia and stomach cancers were made between Cixian, Linxian and Shexian Counties with reference to detection rates of cancer in situ and precancerous lesions of the three upper gastrointestinal cancers by endoscopic screening. The screening was performed from 1999 through 2004 in the three adjacent counties including a total of 6233 local residents aged 40 to 69 years old. Results： The incidence rates for cardia cancer for the male and female from 2000 through 2004 were 69.9 and 41.5, and the mortality rates were 54.3 and 33.2 respectively in Shexian County. Esophageal, cardia, and stomach cancers constitute about 70～80 percent of all malignant disease by incidence or mortality rates. Endoscopic survey with iodine staining can effectively detect squamous cell precancerous lesions in the esophagus, but the method is inadequate for the detection of adeno precancerous lesions of the cardia and stomach. Conclusion： The south Taihang mountain region is a high risk area not only for esophagus cancer, but also for cardia and stomach cancers. To control upper gastrointestinal tract cancers as a whole in the region, special attention should be paid to the control of cardia and stomach cancers. Presently, to find effective screening methods for detecting cardia and stomach precancerous lesions is especially important.展开更多
Objective： To observation the therapeutic effect and the adverse reaction of preoperative induced hypertension chemotherapy （IHC） on the Ⅲ staging cardia or fundus of stomach carcinoma. Methods： 49 cases of the ...Objective： To observation the therapeutic effect and the adverse reaction of preoperative induced hypertension chemotherapy （IHC） on the Ⅲ staging cardia or fundus of stomach carcinoma. Methods： 49 cases of the Ⅲ staging cardia or fundus of stomach carcinoma were divided into two groups at random. The observation group included 19 cases and the control group included 30 cases. Every case used one cycle chemotherapy. The observation group （IHC group） used chemotherapy and AT Ⅱ. The control group （simple chemotherapy group） used simple chemotherapy. All cases of the two groups operated after 3 weeks rest. The specimen＇s DNA was analyzed by flow cytometry. Results： The effective power of observation group was 63.2% （12/19）, exairesis ratio was 84.2% （16/19）. The effective power of control group was 30% （9/30）, exairesis ratio was 63.3% （19/30）. DNA ploid determination： 13 cases were diploid and 5 cases were heteropioid in the observation group, 9 cases were diploid and 16 cases were heteroploid in the control group. The operative complications and risks of the two groups did not increase. Conclusion： IHC can increase the therapeutic effect of Ⅲ staging cardia or fundus of stomach carcinoma obviously. IHC is one of the chemotherapy methods that have good future, it has good value of clinic enlarge trial.展开更多
目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LG...目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LGA共行70次TACE,LIPA共行65次TACE。术前除胃镜和钡餐检查外均行多层螺旋CT三期增强扫描,术中常规行腹主动脉、腹腔动脉及LGA and LIPA造影,准确估计腔内外病变情况,在确认供血范围后将导管逐一超选择至LGA and LIPA支,再分别用碘油-抗癌乳剂栓塞肿瘤末梢血管,然后注入明胶海。结果LGA and LIPA联合化疗栓塞后1、2年、3年生存率分别为88.9%(16/18)、55.6%(10/18)、38.9%(7/18);有4例均行LGA and LIPA化疗栓塞2-3次后行外科手术根治术,已存活4年和5年,目前仍在随访中。未出现一例严重并发症。结论进展期胃底贲门癌术中行腹主动脉、腹腔动脉及LGA and LIPA造影能进一步明确肿瘤的T分期;行LGA and LIPA联合化疗栓塞是一种疗效好、安全性高、科学合理、并发症少且多为自限性的治疗方法。展开更多
基金This work was supported by the grants from The Natural Scientific Foundation of Hebei Province (No. C 2005000797 Hebei Significant Topic of Tackle Key Programs (No. 03276198D) Hebei Technology Program Item (No. 032761100D-1)
文摘Objective： To discuss the epidemic strength of cardia and distant stomach cancers in the high risk region of esophageal cancer along the south Taihang mountain such as in Shexian, Linxian, and Cixian Counties, and to clarify the tasks for the control of upper gastrointestinal tract cancer as a whole in the region. Methods： Comparisons of incidence and mortality rates of esophageal, cardia and stomach cancers were made between Cixian, Linxian and Shexian Counties with reference to detection rates of cancer in situ and precancerous lesions of the three upper gastrointestinal cancers by endoscopic screening. The screening was performed from 1999 through 2004 in the three adjacent counties including a total of 6233 local residents aged 40 to 69 years old. Results： The incidence rates for cardia cancer for the male and female from 2000 through 2004 were 69.9 and 41.5, and the mortality rates were 54.3 and 33.2 respectively in Shexian County. Esophageal, cardia, and stomach cancers constitute about 70～80 percent of all malignant disease by incidence or mortality rates. Endoscopic survey with iodine staining can effectively detect squamous cell precancerous lesions in the esophagus, but the method is inadequate for the detection of adeno precancerous lesions of the cardia and stomach. Conclusion： The south Taihang mountain region is a high risk area not only for esophagus cancer, but also for cardia and stomach cancers. To control upper gastrointestinal tract cancers as a whole in the region, special attention should be paid to the control of cardia and stomach cancers. Presently, to find effective screening methods for detecting cardia and stomach precancerous lesions is especially important.
基金a grant from the Science Foundation of Handan City (No. 02115-3).
文摘Objective： To observation the therapeutic effect and the adverse reaction of preoperative induced hypertension chemotherapy （IHC） on the Ⅲ staging cardia or fundus of stomach carcinoma. Methods： 49 cases of the Ⅲ staging cardia or fundus of stomach carcinoma were divided into two groups at random. The observation group included 19 cases and the control group included 30 cases. Every case used one cycle chemotherapy. The observation group （IHC group） used chemotherapy and AT Ⅱ. The control group （simple chemotherapy group） used simple chemotherapy. All cases of the two groups operated after 3 weeks rest. The specimen＇s DNA was analyzed by flow cytometry. Results： The effective power of observation group was 63.2% （12/19）, exairesis ratio was 84.2% （16/19）. The effective power of control group was 30% （9/30）, exairesis ratio was 63.3% （19/30）. DNA ploid determination： 13 cases were diploid and 5 cases were heteropioid in the observation group, 9 cases were diploid and 16 cases were heteroploid in the control group. The operative complications and risks of the two groups did not increase. Conclusion： IHC can increase the therapeutic effect of Ⅲ staging cardia or fundus of stomach carcinoma obviously. IHC is one of the chemotherapy methods that have good future, it has good value of clinic enlarge trial.
文摘目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LGA共行70次TACE,LIPA共行65次TACE。术前除胃镜和钡餐检查外均行多层螺旋CT三期增强扫描,术中常规行腹主动脉、腹腔动脉及LGA and LIPA造影,准确估计腔内外病变情况,在确认供血范围后将导管逐一超选择至LGA and LIPA支,再分别用碘油-抗癌乳剂栓塞肿瘤末梢血管,然后注入明胶海。结果LGA and LIPA联合化疗栓塞后1、2年、3年生存率分别为88.9%(16/18)、55.6%(10/18)、38.9%(7/18);有4例均行LGA and LIPA化疗栓塞2-3次后行外科手术根治术,已存活4年和5年,目前仍在随访中。未出现一例严重并发症。结论进展期胃底贲门癌术中行腹主动脉、腹腔动脉及LGA and LIPA造影能进一步明确肿瘤的T分期;行LGA and LIPA联合化疗栓塞是一种疗效好、安全性高、科学合理、并发症少且多为自限性的治疗方法。
