With the completion of the Human Genome Project new opportunities have been arisen to more fully characterize the genomic factor contributing to human susceptibility to chemical and pharmacological toxicity. Over 6 mi...With the completion of the Human Genome Project new opportunities have been arisen to more fully characterize the genomic factor contributing to human susceptibility to chemical and pharmacological toxicity. Over 6 million single nucleotide polymorphisms(SNPs) have been identified and cataloged in public databases. Research efforts are now underway to identify which SNPs are associated with variation in disease risk, chemical sensitivity, drug toxicity, as well as drug responsiveness.展开更多
文摘With the completion of the Human Genome Project new opportunities have been arisen to more fully characterize the genomic factor contributing to human susceptibility to chemical and pharmacological toxicity. Over 6 million single nucleotide polymorphisms(SNPs) have been identified and cataloged in public databases. Research efforts are now underway to identify which SNPs are associated with variation in disease risk, chemical sensitivity, drug toxicity, as well as drug responsiveness.