Objective:To explore the efficacy of Lianhua Qingwen Capsule(莲花清瘟胶囊)on upper respiratory tract infection,to understand the impact of Lianhua Qingwen Capsule(莲花清瘟胶囊)on the treatment outcome of upper respira...Objective:To explore the efficacy of Lianhua Qingwen Capsule(莲花清瘟胶囊)on upper respiratory tract infection,to understand the impact of Lianhua Qingwen Capsule(莲花清瘟胶囊)on the treatment outcome of upper respiratory tract infection,and provide reference for rational clinical drug use.Methods:The HIS database based on 18 large third-grade class-A hospitals was selected to match 1:1 for upper respiratory tract infection patients using and without Lianhua Qingwen Capsule(莲花清瘟胶囊)according to certain standards.The recombination of treatment outcome as"recovery"and"improvement"in the database was defined as effective treatment,"ineffectiveness","death"and"other"as ineffectivetreatment populations,and the effectiveness of treatment outcomes in the remerged 2 groups was compared by propensity score method.Results:After matching,454 cases were in both the patients treated by(experimental group)and without(control group)Lianhua Qingwen Capsule(莲花清瘟胶囊).Analysis was performed by three Logistic regression methods,all showing regression coefficients greater than 0 and statistically significant differences(P<0.05).Conclusion:Patients with upper respiratory tract infection treated by Lianhua Qingwen Capsule(莲花清瘟胶囊)are more effective than that without Lianhua Qingwen Capsule(莲花清瘟胶囊),it can improve the clinical efficacy of patients with upper respiratory tract infection。展开更多
目的观察莲花清瘟胶囊联合阿奇霉素治疗高龄患者急性细菌性上呼吸道感染的临床疗效。方法选择7 8例高龄急性细菌性上呼吸道感染患者,随机分成对照组和观察组各39例。对照组予阿奇霉菌治疗,观察组予莲花清温胶囊联合阿奇霉菌治疗,观察对...目的观察莲花清瘟胶囊联合阿奇霉素治疗高龄患者急性细菌性上呼吸道感染的临床疗效。方法选择7 8例高龄急性细菌性上呼吸道感染患者,随机分成对照组和观察组各39例。对照组予阿奇霉菌治疗,观察组予莲花清温胶囊联合阿奇霉菌治疗,观察对比两组患者体温、血白细胞计数(W B C)、超敏C反应蛋白(C R P)和降钙素原(P C T)情况及临床疗效。结果治疗前,两组体温、 W B C、 C R P、 P C T比较,无明显差异(P> 0.0 5);治疗3d后,观察组患者体温、W B C、 C R P、 P C T均明显低于对照组,差异有统计学意义(P <0. 0 5)。观察组临床疗效明显优于对照组,差异有统计学意义(P <0.0 5)。结论莲花清瘟胶囊联合阿奇霉素治疗高龄患者急性细菌性呼吸道感染疗效确切,值得推广。展开更多
基金China Academy of Chinese Medical Sciences Project approval:Science and technology innovation project of China Academy of Chinese Medical Sciences(ci2021a00702)approval:National key R&D plan"demonstration study on evidence-based evaluation and effect mechanism of ten large varieties of Chinese patent medicines and classic famous prescriptions in the treatment of major diseases after listing(2018yfc1707400)。
文摘Objective:To explore the efficacy of Lianhua Qingwen Capsule(莲花清瘟胶囊)on upper respiratory tract infection,to understand the impact of Lianhua Qingwen Capsule(莲花清瘟胶囊)on the treatment outcome of upper respiratory tract infection,and provide reference for rational clinical drug use.Methods:The HIS database based on 18 large third-grade class-A hospitals was selected to match 1:1 for upper respiratory tract infection patients using and without Lianhua Qingwen Capsule(莲花清瘟胶囊)according to certain standards.The recombination of treatment outcome as"recovery"and"improvement"in the database was defined as effective treatment,"ineffectiveness","death"and"other"as ineffectivetreatment populations,and the effectiveness of treatment outcomes in the remerged 2 groups was compared by propensity score method.Results:After matching,454 cases were in both the patients treated by(experimental group)and without(control group)Lianhua Qingwen Capsule(莲花清瘟胶囊).Analysis was performed by three Logistic regression methods,all showing regression coefficients greater than 0 and statistically significant differences(P<0.05).Conclusion:Patients with upper respiratory tract infection treated by Lianhua Qingwen Capsule(莲花清瘟胶囊)are more effective than that without Lianhua Qingwen Capsule(莲花清瘟胶囊),it can improve the clinical efficacy of patients with upper respiratory tract infection。
文摘目的观察莲花清瘟胶囊联合阿奇霉素治疗高龄患者急性细菌性上呼吸道感染的临床疗效。方法选择7 8例高龄急性细菌性上呼吸道感染患者,随机分成对照组和观察组各39例。对照组予阿奇霉菌治疗,观察组予莲花清温胶囊联合阿奇霉菌治疗,观察对比两组患者体温、血白细胞计数(W B C)、超敏C反应蛋白(C R P)和降钙素原(P C T)情况及临床疗效。结果治疗前,两组体温、 W B C、 C R P、 P C T比较,无明显差异(P> 0.0 5);治疗3d后,观察组患者体温、W B C、 C R P、 P C T均明显低于对照组,差异有统计学意义(P <0. 0 5)。观察组临床疗效明显优于对照组,差异有统计学意义(P <0.0 5)。结论莲花清瘟胶囊联合阿奇霉素治疗高龄患者急性细菌性呼吸道感染疗效确切,值得推广。
