This paper presents an alternative representation of a system of differential equations qualitatively showing the behavior of the biological rhythm of a crayfish during their transition from juvenile to adult stages. ...This paper presents an alternative representation of a system of differential equations qualitatively showing the behavior of the biological rhythm of a crayfish during their transition from juvenile to adult stages. The model focuses on the interaction of four cellular oscillators coupled by diffusion of a hormone, a parameter μ is used to simu- late the quality of communication among the oscillators, in biological terms, it mea- sures developmental maturity of the crayfish. Since some quorum-sensing mechanism is assumed to be responsible for the synchronization of the biological oscillators, it is nat- ural to investigate the possibility that the underlying diffusion process is not standard, i.e. it may be a so-called anomalous diffusion. In this case, it is well understood that diffusion equations with fractional derivatives describe these processes in a more realis- tic way. The alternative formulation of these equations contains fractional operators of Liouville-Caputo and Caputo-Fabrizio type. The numerical simulations of the equations reflect synchronization of ultradian rhythms leading to a circadian rhythm. The classical behavior is recovered when the order of the fractional derivative is V = 1. We discuss possible biological implications.展开更多
文摘This paper presents an alternative representation of a system of differential equations qualitatively showing the behavior of the biological rhythm of a crayfish during their transition from juvenile to adult stages. The model focuses on the interaction of four cellular oscillators coupled by diffusion of a hormone, a parameter μ is used to simu- late the quality of communication among the oscillators, in biological terms, it mea- sures developmental maturity of the crayfish. Since some quorum-sensing mechanism is assumed to be responsible for the synchronization of the biological oscillators, it is nat- ural to investigate the possibility that the underlying diffusion process is not standard, i.e. it may be a so-called anomalous diffusion. In this case, it is well understood that diffusion equations with fractional derivatives describe these processes in a more realis- tic way. The alternative formulation of these equations contains fractional operators of Liouville-Caputo and Caputo-Fabrizio type. The numerical simulations of the equations reflect synchronization of ultradian rhythms leading to a circadian rhythm. The classical behavior is recovered when the order of the fractional derivative is V = 1. We discuss possible biological implications.
