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Activation of Carcinogenic Non-aminoazo Compounds iu Horseradish Peroxidase/H_2O_2 System
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作者 Min ZHU Xue Mei HUANG and Han Xi SHEN (Department of Chemistry, Nankai University, Tianjin, 300071) 《Chinese Chemical Letters》 SCIE CAS CSCD 1997年第11期979-982,共4页
Eriochrome black T and Nitrosulfophenol S were advocated as the chemical models of carcinogenic non-aminoazo compounds. The main products of their oxidative cleavage in horseradish peroxidase/H2O2 system was identifie... Eriochrome black T and Nitrosulfophenol S were advocated as the chemical models of carcinogenic non-aminoazo compounds. The main products of their oxidative cleavage in horseradish peroxidase/H2O2 system was identified as the benezenediazonium ion, the ultimate carcinogens, which could bind to DNA. The reaction conditions were investigated preliminarily. Some inhibitors and inducers of the reaction were discovered. 展开更多
关键词 MILLER Activation of carcinogenic Non-aminoazo compounds in Horseradish Peroxidase/H2O2 System
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