We focus specifically on the rare occurrence of cardiac thrombi in Li-Fraumeni syndrome(LFS).LFS is a hereditary risk to a diverse range of specific,uncommon,malignancies.Children and young adults have a heightened su...We focus specifically on the rare occurrence of cardiac thrombi in Li-Fraumeni syndrome(LFS).LFS is a hereditary risk to a diverse range of specific,uncommon,malignancies.Children and young adults have a heightened susceptibility to many malignancies,particularly soft-tissue and bone tumors,breast malignancies,central nervous system malignancies,adrenocortical carcinoma,and blood cancers.Additionally,LFS patients may experience other cancer types such as gastrointestinal,lung,kidney,thyroid,and skin cancers,along with those affecting gonadal organs(ovaries,testicles,and prostate).An accurate diagnosis of LFS is crucial to enable affected families to access appropriate genetic counseling and undergo surveillance for early cancer detection.展开更多
文摘We focus specifically on the rare occurrence of cardiac thrombi in Li-Fraumeni syndrome(LFS).LFS is a hereditary risk to a diverse range of specific,uncommon,malignancies.Children and young adults have a heightened susceptibility to many malignancies,particularly soft-tissue and bone tumors,breast malignancies,central nervous system malignancies,adrenocortical carcinoma,and blood cancers.Additionally,LFS patients may experience other cancer types such as gastrointestinal,lung,kidney,thyroid,and skin cancers,along with those affecting gonadal organs(ovaries,testicles,and prostate).An accurate diagnosis of LFS is crucial to enable affected families to access appropriate genetic counseling and undergo surveillance for early cancer detection.
