Background: In Japan, due to the COVID-19 pandemic, various behavioral restrictions were implemented from March 2020, resulting in an increased number of elderly people with reduced participation in care and rehabilit...Background: In Japan, due to the COVID-19 pandemic, various behavioral restrictions were implemented from March 2020, resulting in an increased number of elderly people with reduced participation in care and rehabilitation. As a result, the decline in motor and cognitive functions became more pronounced. Purpose: The study examined how activities combining passive horticultural therapy, which is always introduced, with active functional recovery training, which is used in the functional recovery training of patients with hemiplegia, influence the behavior of elder people using the facility. Methods: 36 elder people with care need 1 or 2 who regularly used the day-care facilities after the pandemic ended and who agreed to participate in the study was included. The assessment data were every three months from December 2021 to December 2023 after the COVID-19 pandemic, the MMSE and Moca-J, TMIG-Index, and GDS15. AI-based text mining was used to compare changes in visit reports before and after the introduction of the Posture Chart and Red Code, and the relationship between the language used. Results: The results of MMSE and Moca-J were both significantly higher in Group B and C than in Group A. TIMG assessment, was significantly higher in Group B and C than in Group A, and Group C was significantly higher than Group B. The GDS, an assessment of depression in old age, tended to be significantly higher in Group A than in Groups B and C. In the “Co-Occurrence Network Analysis” shown after the introduction of the latest functional recovery training equipment such as the Red Cord, its results showed a high association between the words Bathing and CARE and words such as POSTURE, Red-Code, and AI, App, which are used in functional training and rehabilitation, and their analysis. Conclusion: At day-care facilities specializing in functional recovery training and rehabilitation, a combination of horticultural therapy and the latest functional training equipment found to help maintain the physical and mental health of elderly people certified as requiring nursing care. Since this is a short-term study following behavioral restrictions, long-term research should continue to study the effects of adding functional training, handled by rehabilitation professionals, to horticultural therapy.展开更多
<strong>Background:</strong> Human immunodeficiency virus (HIV) and hepatitis virus (HBV) coinfection are common due to shared modes of transmission between these viruses. Also studies have shown that HIV ...<strong>Background:</strong> Human immunodeficiency virus (HIV) and hepatitis virus (HBV) coinfection are common due to shared modes of transmission between these viruses. Also studies have shown that HIV appears to be a risk factor for reactivation of hepatitis B in patients who have developed hepatitis B surface antibodies HBsAg which is considered as a marker of chronic HBV infection. The magnitude of HIV/HBV coinfection among people living with HIV in Tanzania is not well known.<strong> Objective:</strong> The aim of this study was to determine the prevalence and associated factors of HBsAg among HIV Positive Clients at CTC at Mawenzi Regional Hospital. <strong>Methods:</strong> It was a cross sectional study that included 100 HIV Positive CTC clients at Mawenzi Regional Hospital. Ethical clearance was obtained at KCMUCo ethical committee, structured questionnaires with closed-ended question were used to collect the information needed done by interviewing the person, blood sample was collected from median cubital vein and HBsAg Rapid Test Strips were used. Data processing and analysis were done using SPSS version 20. <strong>Results:</strong> Of 100 HIV patients, only 8 (8%) tested positively for HBsAg. There was a significant association between residence and HBV infection. People from rural areas had high prevalence compared to urban areas (OR 8.71, 95% CI: 1.029 - 73.66). Other social demographic and clinical characteristics in this study had no significant association with HBsAg positivity. <strong>Conclusion: </strong>Significant numbers of 8% HIV patients are HBsAg positive. HIV patients from rural residency are more likely to acquire HBV than Urban residents that showed significant association.展开更多
New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individua...New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.展开更多
目的探讨3D急救模式在胸痛中心抢救中的应用效果。方法选取2019年4月至8月英德市人民医院急诊科胸痛中心收治的58例胸痛患者为观察组,2017年1月至2018年6月同院未成立胸痛中心期间收治的37例胸痛患者为对照组。对照组采用常规急救流程,...目的探讨3D急救模式在胸痛中心抢救中的应用效果。方法选取2019年4月至8月英德市人民医院急诊科胸痛中心收治的58例胸痛患者为观察组,2017年1月至2018年6月同院未成立胸痛中心期间收治的37例胸痛患者为对照组。对照组采用常规急救流程,观察组采用胸痛中心3D急救模式。比较两组入门至球囊扩张时间(D to B时间)、首次医疗接触到首份心电图时间、首份心电图完成至首份心电图确诊时间、肌钙蛋白获得时间、导管室激活时间及远程传输比例。结果观察组D to B时间、首次医疗接触到首份心电图时间、首份心电图完成至首份心电图确诊时间、肌钙蛋白获得时间、导管室激活时间短于对照组,远程传输比例高于对照组,差异有统计学意义(P<0.05)。结论3D急救模式应用于胸痛中心抢救中,利于缩短各项诊治环节所需时间,提高救治效率,值得临床应用。展开更多
文摘Background: In Japan, due to the COVID-19 pandemic, various behavioral restrictions were implemented from March 2020, resulting in an increased number of elderly people with reduced participation in care and rehabilitation. As a result, the decline in motor and cognitive functions became more pronounced. Purpose: The study examined how activities combining passive horticultural therapy, which is always introduced, with active functional recovery training, which is used in the functional recovery training of patients with hemiplegia, influence the behavior of elder people using the facility. Methods: 36 elder people with care need 1 or 2 who regularly used the day-care facilities after the pandemic ended and who agreed to participate in the study was included. The assessment data were every three months from December 2021 to December 2023 after the COVID-19 pandemic, the MMSE and Moca-J, TMIG-Index, and GDS15. AI-based text mining was used to compare changes in visit reports before and after the introduction of the Posture Chart and Red Code, and the relationship between the language used. Results: The results of MMSE and Moca-J were both significantly higher in Group B and C than in Group A. TIMG assessment, was significantly higher in Group B and C than in Group A, and Group C was significantly higher than Group B. The GDS, an assessment of depression in old age, tended to be significantly higher in Group A than in Groups B and C. In the “Co-Occurrence Network Analysis” shown after the introduction of the latest functional recovery training equipment such as the Red Cord, its results showed a high association between the words Bathing and CARE and words such as POSTURE, Red-Code, and AI, App, which are used in functional training and rehabilitation, and their analysis. Conclusion: At day-care facilities specializing in functional recovery training and rehabilitation, a combination of horticultural therapy and the latest functional training equipment found to help maintain the physical and mental health of elderly people certified as requiring nursing care. Since this is a short-term study following behavioral restrictions, long-term research should continue to study the effects of adding functional training, handled by rehabilitation professionals, to horticultural therapy.
文摘<strong>Background:</strong> Human immunodeficiency virus (HIV) and hepatitis virus (HBV) coinfection are common due to shared modes of transmission between these viruses. Also studies have shown that HIV appears to be a risk factor for reactivation of hepatitis B in patients who have developed hepatitis B surface antibodies HBsAg which is considered as a marker of chronic HBV infection. The magnitude of HIV/HBV coinfection among people living with HIV in Tanzania is not well known.<strong> Objective:</strong> The aim of this study was to determine the prevalence and associated factors of HBsAg among HIV Positive Clients at CTC at Mawenzi Regional Hospital. <strong>Methods:</strong> It was a cross sectional study that included 100 HIV Positive CTC clients at Mawenzi Regional Hospital. Ethical clearance was obtained at KCMUCo ethical committee, structured questionnaires with closed-ended question were used to collect the information needed done by interviewing the person, blood sample was collected from median cubital vein and HBsAg Rapid Test Strips were used. Data processing and analysis were done using SPSS version 20. <strong>Results:</strong> Of 100 HIV patients, only 8 (8%) tested positively for HBsAg. There was a significant association between residence and HBV infection. People from rural areas had high prevalence compared to urban areas (OR 8.71, 95% CI: 1.029 - 73.66). Other social demographic and clinical characteristics in this study had no significant association with HBsAg positivity. <strong>Conclusion: </strong>Significant numbers of 8% HIV patients are HBsAg positive. HIV patients from rural residency are more likely to acquire HBV than Urban residents that showed significant association.
文摘New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.
文摘目的探讨3D急救模式在胸痛中心抢救中的应用效果。方法选取2019年4月至8月英德市人民医院急诊科胸痛中心收治的58例胸痛患者为观察组,2017年1月至2018年6月同院未成立胸痛中心期间收治的37例胸痛患者为对照组。对照组采用常规急救流程,观察组采用胸痛中心3D急救模式。比较两组入门至球囊扩张时间(D to B时间)、首次医疗接触到首份心电图时间、首份心电图完成至首份心电图确诊时间、肌钙蛋白获得时间、导管室激活时间及远程传输比例。结果观察组D to B时间、首次医疗接触到首份心电图时间、首份心电图完成至首份心电图确诊时间、肌钙蛋白获得时间、导管室激活时间短于对照组,远程传输比例高于对照组,差异有统计学意义(P<0.05)。结论3D急救模式应用于胸痛中心抢救中,利于缩短各项诊治环节所需时间,提高救治效率,值得临床应用。