Phytoecdysterones from Cucubalus baccifer (Caryophyllaceae)

Six phytoecdysterones have been isolated from the n-BuOH portion of Cucubalus baccifer L., a Chinese folk medicinal plant. Their structures were elucidated as ecdysterone (1), 24(28)-ecdysterone (2), 22-deoxyecdysterone (3), 25-hydroxypanuosterone (4), rubrosterone (5) and 2,22-dideoxyecdysterone 3 beta -O-beta -D-glucopyranoside (6) respectively on the basis of spectroscopic and chemical methods. Among them compound 6 was a new phytoecdysterone glycoside and 1-5 were first obtained from this plant.

Cyclopeptides from Polycarpon prostratum (Caryophyllaceae)

Two new cyclic peptides, polycarponin B and C (1, 2), were isolated from the whole plants of Polycarpon prostratum (Forssk.) Aschers. et Schwein. ex Aschers. By detailed spectroscopic analysis, their structures were determined as cyclo(-Gly(1)-Ile-Val(1)-Leu(1)-Val(2)-Gly(2)-Leu(2)-Pro) and cyclo(-Pro(1)-Thr-Leu(1)-Pro(2)-Pro(3)-Val-Leu(2)-Phe), respectively.

New Triterpenoid Saponins from Polycarpon prostratum (Caryophyllaceae)

Three new triterpenoid saponins, namely prostratosides A-C (1-3), were isolated from the whole plant of Polycarpon prostratum (Forssk.) Aschers. et Schwein. ex Aschers. By spectroscopic methods, their structures were determined as 3_O_{β_D_xylopyranosyl_(1→2)_β_D_glucopyranosyl_(1→4)_[β_D_glucopyranosyl_(1→2)]_α_L_arabinopyranoside}_22α_acetoxy_saikogenin G, 3_O_{β_D_xylopyranosyl_(1→2)_β_D_glucopyranosyl_(1→4)_[β_D_glucopyranosyl_(1→2)]_α_L_arabinopyranoside}_16α_hydroxy_22α_acetoxy_saikogenin E and 3_O_{β_D_xylopyranosyl_(1→2)_β_D_glucopyranosyl_(1→4)_[β_D_glucopyranosyl_(1→2)]_α_L_arabinopyranoside}_21β_acetoxy_saikogenin G, respectively.

New Minor Cyclopeptides from Arenaria oreophila (Caryophyllaceae)

New minor cyclic peptides, named arenariphilin C 1 and arenariphilin D 2, were isolated from the whole plants of Arenaria oreophila （Caryophyllaceae）. Their structures were determined as cyclo（Pro^1-Pro2-Leu^1-Leu2-Phe-Ser-Gly-Thr） and cyclo （Ser-Cys） on the basis of spectroscopic data, especially by two-dimension NMR （2D NMR） technologies.

Effects of Intercropping with CaryophyllaceaeAccumulator Plants on Cadmium Accumulation ofCyphomandra betacea Seedlings

The pot experiments were conducted to study the effects of intercropping with Pseudostellaria maximowicziana,Malachiumaquaticum and Stellaria media on Cd accumulation of Cyphomandra betacea seedlings.Compared with the monoculture,intercropping with Caryophyllaceae endarachneyllaceae accumulator plants decreased the biomass of C.betacea seedlings,and also reduced the photosynthetic pigment contents in C.betacea seedlings,which involve chlorophyll a,chlorophyll b,total chlorophyll and carotenoid.Intercropping with P.maximowicziana and M.aquaticum increased the Cd contents in shoots of C.betacea seedlings,which increased by 65.02%and 25.61%,respectively,compared with the monoculture.Intercropping with S.media reduced the Cd contents in shoots of C.betacea seedlings,which were reduced by 4.68%compared with the monoculture.When intercropping with C.betacea seedlings,the Cd accumulation amounts of 3 Caryophyllaceae accumulator plants were ranked as S.media>P.maximowicziana>M.aquaticum.Intercropping with S.media could effectively reduce Cd accumulation of C.betacea seedlings under Cd-contaminated soil condition.

<i>Drymaria cordata</i>(Linn.) Willd (Caryophyllaceae): Ethnobotany, Pharmacology and Phytochemistry

In the present paper the isolation and characterization of seven major glycolipid classes (stigmasterol, acylated stigmasteryl glucoside, stigmasteryl glucoside, monogalactosyldiacylglycerol, digalactosyldiacylglycerol, cerebroside and glucocerebroside) from Drymaria cordata (Linn.) Willd (Caryophyllaceae Family) are reported after an attempt has been made to congregate the traditional and pharmacological studies done on this important medicinal plant. Drymaria cordata is a weak spreading herb found widely dispersed in damp places all over the tropics of Africa, Asia and the Americas. There are many reports on its folk and traditional uses that include snake bite, skin diseases, peptic ulcer, headaches or nephritis, female infertility, sleeping disorders, convulsions, and febrile conditions in children. The plant has been examined on the basis of scientific in vitro and in vivo evaluations possessing the major pharmacological activities that include analgesic activity, antitussive activity, anxiolytic activity, antipyretic activity, antinociceptive activity, anti-inflammatory and antibacterial activities. The information summarized here is intended to serve as a reference tool for practitioners in the fields of ethnopharmacology, natural product chemistry and drug discovery related research.

Cyclopeptidic Constituents from Arenaria oreophila J.D,Hooker(Caryophyllaceae)

To further investigate the cyclopeptldes of the Caryophyllaceae family, two new cyclopeptldes, named Arenarlphilin E （compound 1） and Arenariphilin F （compound 2）, were obtained from Arenaria oreophUe J. D. Hooker using some Isolation methods, e. g. normal and reverse silica gel. By detailed spectroscopic analysis, such as FAB^＋-MS, 1 D NMR, 2D NMR, the structures of Arenariphilin E （compound 1） and Arenariphilln F （compound 2） were determined as cyclo（lle^1-Gly-Val^1-Ala-Leu-lle^3-lle^2-Val^2-Pro） and cyclo（Pro^2-Pro^1-Gly^2-lle-Val-Leu-Gly^1-AiaThr- Gly^3）, respectively.

New Minor Cyclic Peptides from Brachystemma calycinum

From the ethanol extract of the roots of Brachystemma calycinum D. Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1 - 4) have been isolated. Their structures were established as cyclo (Pro(1)-Phe-Leu-Ala(1)-Thr-Pro(2)-Ala(2)-Gly) (1), cyclo (Pro(1)-Ala-Phe-Trp-Asp-Pro(2)-Leu-Gly) (2), cyclo (Pro(1)-Ile-Gly-Pro(2)-Val-Ala(1)-Ala(2)-Tyr) (3) and cyclo ( Pro-OMet-Trp-Ile-Gly-Ala-Leu-Asp) (4) respectively by means of extensive spectral methods.

Segetoside L, A New Triterpenoid Saponin from Vaccaria segetalis

A new triterpenoid saponin, named segetoside L, was isolated from the seeds of Vaccaria segetalis. On the basis of spectral data and chemical reaction, its structure was established as 28-O-b-D-glucopyranosyl-(16)-b-D-glucopyranosyl oleanolic acid 3-O-b-D- glucopyranosyl-(13)-[b-D-galactopyranosyl-(12)]-b-D-galactopyranoside.

A new cyclopeptide from Dianthus caryophyllus

A new cyclopeptide as well as a known cyclopeptide were isolated from the whole plants of Dianthus caryophyllus. Their structures were elucidated as cyclo （-Thr-Gly-Pro-Tyr-Phe-） （1） and cyclo （-Ala-Gly-Ser-IIe-Phe-Phe-） （2） by means of chemical and spectroscopic methods including MS, 1D and 2D NMR techniques.

A New Cyclopeptide from Polycarpon prostratum

A new cyclic peptide named polycarponin A, was isolated from the whole plants of Polycarpon prostratum. Its structure was determined by detailed spectroscopic analysis.

Three New Saikosaponin-like Compounds from Polycarpon prostratum

Three new saikosaponin-like compounds (named prostratoside F-H) were isolated from the whole plants of Polycarpon prostratum (Forssk.) Aschers. et Schwein. ex Aschers. By detailed spectroscopic analysis, their structures were determined as 13 beta, 28-epoxy-16-keto-22 alpha, 23-dihydroxyolean-11-en-3 beta -yl-alpha -L-arabinopyranoside, 13 beta, 28-epoxy-16-keto-23-hydroxy-olean-11-en-3 beta -yl-alpha -L-arabinopyranoside and 13 beta, 28-epoxy-16-keto-22 alpha -hydroxyolean-11-en-3 beta -yl-alpha -L-arabinopyranoside, respectively.

A New Cyclopeptide from Brachystemma calycinum

A new cyclopeptide, brachystemin A, has been isolated from the roots of Brachystemma calycinum. The structure was elucidated by spectral methods.

A Triterpenoid Saponin from Polycarpon prostratum

A new triterpenoid saponin, named prostratoside A. was isolated from the whole plants of Polycarpon prostratum. Its structure nas determined to be 3-O-{beta-D-xylopyranosyl- (1-->2)- beta-D-glucopranosyl-(1-->4)-[ beta- D-plucopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl}- 22 alpha- acetoxy saikogenin G by spectroscopic methods..

Stellarins F and G, two new cyclopeptides from Stellaria yunnanensis

In the previous papers, we reported the structural elucidation of stellarins A-E, five new cyclopeptides from the fresh roots of Stellaria yunnanensis Franch. Further chemical study on this plant led to the isolation of two other new cyclopeptide named stellarins F(1) and G(2). By a combination of 2D-NMR, enzymatic degradation and FABMS, their structures were established to by cyclo(Gly-Ala-Gly-Ser-Pro-Trp-Phe-Pro) and cyclo(Gly-Ala-Tyr-Leu-Ala), respectively.

Three New Flavone Glycosides from Drymaria diandra B1.

In order to find new structural and biologically active compounds, the constituents from the whole plant of Drymaria diandra B1. （Caryophyllaceae） were investigated and three new flavone glycosides, named drymariatins B （1）, C （2）, and D （3）, were isolated by solvent partition, Si gel, sephadex LH-20, and Rp- 18 column chromatography. Using spectroscopic methods, including two-dimensional nuclear magnetic resonance analysis, the structures of these compounds were elucidated as 6-C-（2-deoxy-β-D-fucopyranosyl）- 5,7,4＇-trihydroxyl-flavone, 6-C-（2-deoxy-β-D-fucopyranosyl）-7-O-（β-D-glucopyranosyl）-5,4＇-dibydroxyl- flavone, and 6-C-（3-keto-β-digitoxopyranosyl）-7-O-（β-D-glucopyranosyl）-5,4＇-dihydroxyl-flavone.

Two new β-carboline-type alkaloids from Stellaria dichotoma var.lanceolata

Two new β-carboline-type alkaloids, dichotomine K （1） and dichotomine L （2）, were isolated from the roots of Chinese medicinal plant Stellaria dichotoma L. vat. lanceolata Bge. Structures of 1 and 2 were determined on the basis of chemical and spectroscopic means.

Triterpenoid Saponins from Roots of Gypsophila pacifica

Objective To study the chemical constituents from the roots of Gypsophila pacifica.Methods The chemical constituents were isolated by various column chromatographic methods and their structures were identified by spectral data together with physicochemical analysis.Results Five compounds were isolated and identified as 3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl gypsogenin 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside(1),3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl quillaic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside(2),3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl gypsogenin 28-O-β-D-glucopyranosyl-(1→3)-[β-D-xylopyranosyl-(1→4)]-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside(3),3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl quillaic acid 28-O-β-D-glucopyranosyl-(1→3)-[β-D-xylopyranosyl-(1→4)]-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside(4),3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl quillaic acid 28-O-α-L-arabino-pyranosyl-(1→4)-α-L-arabinopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside(5).Conclusion The five compounds are isolated from this plant for the first time.