Alzheimer’s disease(AD)is a prevalent neurodegenerative disease in the aged population1.Etiology of AD remains largely unknown and no effective drugs are available in clinical settings to reverse or delay the disease...Alzheimer’s disease(AD)is a prevalent neurodegenerative disease in the aged population1.Etiology of AD remains largely unknown and no effective drugs are available in clinical settings to reverse or delay the disease progress2.In recent years,the brain’s lymphatic systems,including glymphatic3 that exists in the brain interstitial space and meningeal lymphatic vessels4 that presents within the dural sinuses,have been found to play an important role in the AD pathogenesis.展开更多
基金supported by a project(32271220)from the National Natural Science Foundation of China to Jianping Ye.
文摘Alzheimer’s disease(AD)is a prevalent neurodegenerative disease in the aged population1.Etiology of AD remains largely unknown and no effective drugs are available in clinical settings to reverse or delay the disease progress2.In recent years,the brain’s lymphatic systems,including glymphatic3 that exists in the brain interstitial space and meningeal lymphatic vessels4 that presents within the dural sinuses,have been found to play an important role in the AD pathogenesis.