BACKGROUND: Two classification systems exist for subtypes of acute cerebral infarction. One was developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST), based primarily on etiology. The other is the ...BACKGROUND: Two classification systems exist for subtypes of acute cerebral infarction. One was developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST), based primarily on etiology. The other is the Oxfordshire Community Stroke Project (OCSP), based on clinical features. OBJECTIVE: To evaluate the relationship between OCSP and TOAST classifications in terms of stroke location and etiology in 126 patients with acute ischemic stroke confirmed by transcranial magnetic resonance imaging (MRI). DESIGN, TIME AND SETTING: Retrospective case analysis. Transcranial MRI, diffusion weighted imaging, and magnetic resonance angiography were performed in 126 patients with acute stroke during the first 48 hours following admission to the Department of Neurology, Navy General Hospital of Chinese PLA. PARTICIPANTS: A total of 126 patients with acute stroke, comprised of 71 males and 55 females, admitted to the Navy General Hospital of Chinese PLA between December 2005 and April 2006 were included. METHODS: Of 126 patients with acute stroke, 13 exhibited total anterior circulation infarcts (TACI), 51 had partial anterior circulation infarcts (PACI), 28 suffered posterior circulation infarcts (POCI), and 34 had lacunar infarcts (LACI) based on OCSP classification. However, according to TOAST classification, 19 cases were a result of large-artery atherosclerosis, 32 by cardioembolism, 36 by small-vessel occlusion, 1 by stroke of other determined etiology, and 38 by stroke of undetermined etiology. MAIN OUTCOME MEASURES: The corresponding relationship of the subtypes of acute stroke based on OCSP and TOAST. RESULTS: Of patients with TACI, 8 (61.5%) were caused by cardioembolism. Of patients with PACI, 16 (31.4%) were caused by large-artery atherosclerosis and 17 (33.3%) by cardioembolism. Of patients with POCI, 12 (42.8%) were a result of small-vessel occlusion. Of patients with LACI, 17 (50.0%) were caused by hypertension and arteriolar sclerosis. CONCLUSION: (1) The OCSP system is related to anatomical and pathophysiological processes, and can correctly identify the size, location, and cause of cerebral infarcts. It can also act as a reference for prognosis estimation and recurrence prevention of ischemic stroke. (2) The stroke of undetermined etiology occupies the largest percent in the subtypes of stroke, according to TOAST. (3) The classification of OCSP exhibits a close relationship to TOAST.展开更多
目的 验证OCSP(Oxfordshire Community Stroke Poject)分型法在急性脑梗死临床中的使用价值。方法回顾分析我院近2年202例急性脑梗塞早期OCSP分型情况及影像学特征。结果OCSP分型与影像学结果有良好对应关系;我院急性脑梗死的亚型构成...目的 验证OCSP(Oxfordshire Community Stroke Poject)分型法在急性脑梗死临床中的使用价值。方法回顾分析我院近2年202例急性脑梗塞早期OCSP分型情况及影像学特征。结果OCSP分型与影像学结果有良好对应关系;我院急性脑梗死的亚型构成:脑隙性脑梗塞占65.3%,部分前循环梗塞19.3%,完全前循环梗塞9.9%,后循环梗塞5.4%。结论OCSP法可用于急性脑梗死的早期分型、指导治疗、评估预后;我国急性脑梗死的亚型构成中轻型病例多,重型少。展开更多
目的探讨急性脑梗死牛津郡社区卒中项目(OCSP)分型与影像学分型的对应关系。方法回顾性分析236例急性脑梗死患者早期OCSP分型情况及其影像学特征。结果按OCSP分型:完全性前循环梗死(TAC I)28例(11.9%),部分性前循环梗死(PAC I)71例(30.1...目的探讨急性脑梗死牛津郡社区卒中项目(OCSP)分型与影像学分型的对应关系。方法回顾性分析236例急性脑梗死患者早期OCSP分型情况及其影像学特征。结果按OCSP分型:完全性前循环梗死(TAC I)28例(11.9%),部分性前循环梗死(PAC I)71例(30.1%),腔隙性梗死(LAC I)94例(39.8%),后循环梗死(POC I)43例(18.2%)。临床分型与影像学分型一致者共有171例,分型总准确率72.5%(171/236);各亚型分型准确率分别为TAC I 76%(25/33),PAC I 81%(34/42),LAC I71%(81/114),POC I 66%(31/47)。结论OCSP分型能正确预测梗阻部位和大小,与影像学检查结果有良好的对应关系。展开更多
文摘BACKGROUND: Two classification systems exist for subtypes of acute cerebral infarction. One was developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST), based primarily on etiology. The other is the Oxfordshire Community Stroke Project (OCSP), based on clinical features. OBJECTIVE: To evaluate the relationship between OCSP and TOAST classifications in terms of stroke location and etiology in 126 patients with acute ischemic stroke confirmed by transcranial magnetic resonance imaging (MRI). DESIGN, TIME AND SETTING: Retrospective case analysis. Transcranial MRI, diffusion weighted imaging, and magnetic resonance angiography were performed in 126 patients with acute stroke during the first 48 hours following admission to the Department of Neurology, Navy General Hospital of Chinese PLA. PARTICIPANTS: A total of 126 patients with acute stroke, comprised of 71 males and 55 females, admitted to the Navy General Hospital of Chinese PLA between December 2005 and April 2006 were included. METHODS: Of 126 patients with acute stroke, 13 exhibited total anterior circulation infarcts (TACI), 51 had partial anterior circulation infarcts (PACI), 28 suffered posterior circulation infarcts (POCI), and 34 had lacunar infarcts (LACI) based on OCSP classification. However, according to TOAST classification, 19 cases were a result of large-artery atherosclerosis, 32 by cardioembolism, 36 by small-vessel occlusion, 1 by stroke of other determined etiology, and 38 by stroke of undetermined etiology. MAIN OUTCOME MEASURES: The corresponding relationship of the subtypes of acute stroke based on OCSP and TOAST. RESULTS: Of patients with TACI, 8 (61.5%) were caused by cardioembolism. Of patients with PACI, 16 (31.4%) were caused by large-artery atherosclerosis and 17 (33.3%) by cardioembolism. Of patients with POCI, 12 (42.8%) were a result of small-vessel occlusion. Of patients with LACI, 17 (50.0%) were caused by hypertension and arteriolar sclerosis. CONCLUSION: (1) The OCSP system is related to anatomical and pathophysiological processes, and can correctly identify the size, location, and cause of cerebral infarcts. It can also act as a reference for prognosis estimation and recurrence prevention of ischemic stroke. (2) The stroke of undetermined etiology occupies the largest percent in the subtypes of stroke, according to TOAST. (3) The classification of OCSP exhibits a close relationship to TOAST.
文摘目的 验证OCSP(Oxfordshire Community Stroke Poject)分型法在急性脑梗死临床中的使用价值。方法回顾分析我院近2年202例急性脑梗塞早期OCSP分型情况及影像学特征。结果OCSP分型与影像学结果有良好对应关系;我院急性脑梗死的亚型构成:脑隙性脑梗塞占65.3%,部分前循环梗塞19.3%,完全前循环梗塞9.9%,后循环梗塞5.4%。结论OCSP法可用于急性脑梗死的早期分型、指导治疗、评估预后;我国急性脑梗死的亚型构成中轻型病例多,重型少。
文摘目的探讨急性脑梗死牛津郡社区卒中项目(OCSP)分型与影像学分型的对应关系。方法回顾性分析236例急性脑梗死患者早期OCSP分型情况及其影像学特征。结果按OCSP分型:完全性前循环梗死(TAC I)28例(11.9%),部分性前循环梗死(PAC I)71例(30.1%),腔隙性梗死(LAC I)94例(39.8%),后循环梗死(POC I)43例(18.2%)。临床分型与影像学分型一致者共有171例,分型总准确率72.5%(171/236);各亚型分型准确率分别为TAC I 76%(25/33),PAC I 81%(34/42),LAC I71%(81/114),POC I 66%(31/47)。结论OCSP分型能正确预测梗阻部位和大小,与影像学检查结果有良好的对应关系。